• Transportation Technology and Policy
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• v.11 no.6
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• pp.19-23
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• 2014

• Korean Institute of Interior Design Journal
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• v.13 no.2
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• pp.80-90
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• 2004

Scientism is a kind of paradigm since the birth of Modernism. Architectural design was also effected from scientism in the 1st Machine age, and being effected still In the End Machine age. But many architects in the 2nd Machine age express scientism in architectural design as a "science for kick" as SF. The design of Rem Koolhaas follows the line of Modernism which was effected from scientism in many ways. However he shows modified machine aesthetics as SF pataphysics mixed with literary imagination, and now shows new science paradigm in post-modern age. He expresses many new science theory like indeterminacy theory, chaos, catastrophe theory in his works. And those are expressed as indeterminate program that proceeds in non-linear way, rhizome in space, order out of chaos, topological metamorphosis as a catastrophe. This study analyzes the expression of scientism in architectural design of Rem Koolhaas since 1970s.nce 1970s.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1871-1877
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• 2014

Enhancing of radioresponsiveness of tumors by using radiosensitizers is a promising approach to increase the efficacy of radiation therapy. Recently, the ethanolic extract of the medicinal plant, Derris scandens Benth has been identified as a potent radiosensitizer of human colon cancer HT29 cells. However, cell death mechanisms underlying radiosensitization activity of D scandens extract have not been identified. Here, we show that treatment of HT-29 cells with D scandens extract in combination with gamma irradiation synergistically sensitizes HT-29 cells to cell lethality by apoptosis and mitotic catastrophe. Furthermore, the extract was found to decrease Erk1/2 activation. These findings suggest that D scandens extract mediates radiosensitization via at least two distinct modes of cell death and silences pro-survival signaling in HT-29 cells.

• Journal of Internet Computing and Services
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• v.16 no.3
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• pp.105-116
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• 2015

The Sewol ferry catastrophe that took place on April 16 2014 was unprecedented in terms of its sociopolitical implications, which had reverberated throughout the Korean nation. Mindful of such distinct characteristics of the Sewol ferry catastrophe, this thesis looks into the salience of the agendas portrayed in Twitter and Portal News coverage on the disaster and the correlation between the attribute-specific agendas of the foregoing mediums by making use of the agenda rank order correlation method. Extraction and analysis of big data revealed that first, while the hypothesis that there were little difference in terms of salience among the main agendas between Twitter and Portal News was dismissed, the rank order correlation proved to be high as regards the main agendas on Twitter and Portal News. This signifies that Twitter agendas exert influence over those on Portal News. Next, and regarding the five main agendas on the incident, there existed differences in salience between the attribute-specific agendas of the two mediums, with low figures for corresponding rank order correlations. Such results signify that Twitter and Portal News have little influence over each other as regards their agenda rank order correlation.

• Fire Protection Technology
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• s.11
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• pp.9-12
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• 1991

Together with the development of which being sharp scientific civilization everydays,it is the situation that cannot forecast and analyse with common sense due to being malformation of every kinds of disaster appearance. So, I suggest the theory of new protection and new system with most sensors, contrd box, and reconsideration and develop for it's assembly for the protection of such a catastrophe.

• Wind and Structures
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• v.23 no.5
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• pp.449-464
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• 2016

Catastrophe models appraise the natural risk of the built-infrastructure simulating the interaction of its exposure and vulnerability with a hazard. Because of unique configurations and reduced number, mid/high-rise buildings present singular challenges to the assessment of their damage vulnerability. This paper presents a novel approach to estimate the vulnerability of mid/high-rise buildings (MHB) which is used in the Florida Public Hurricane Loss Model, a catastrophe model developed for the state of Florida. The MHB vulnerability approach considers the wind pressure hazard exerted over the building's height as well as accompanying rain. The approach assesses separately the damages caused by wind, debris impact, and water intrusion on building models discretized into typical apartment units. Hurricane-induced water intrusion is predicted combining the estimates of impinging rain with breach and pre-existing building defect size estimates. Damage is aggregated apartment-by-apartment and story-by-story, and accounts for vertical water propagation. The approach enables the vulnerability modeling of regular and complex building geometries in the Florida exposure and elsewhere.

• Geomechanics and Engineering
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• v.14 no.5
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• pp.439-451
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• 2018

The stress path characteristics of surrounding rock in the formation of gob were analysed and the unloading was solved. Taking Chengchao Iron Mine as the engineering background, the model for analysing the instability of deep gob was established based on the mechanism of stress relief in deep mining. The energy evolution law was investigated by introducing the local energy release rate index (LERR), and the energy criterion of instability of surrounding rock was established based on the cusp catastrophe theory. The results showed that the evolution equation of the local energy release energy of the surrounding rock was quartic function with one unknown and the release rate increased gradually during the mining. The calculation results showed that the gob was stable. The LERR per unit volume of the bottom structure was relatively smaller, which mean the stability was better. The LERR distribution showed that there was main energy release in the horizontal direction and energy concentration in the vertical direction which meet the characteristics of deep mining. In summary, this model could effectively calculate the stability of surrounding rock in the formation of gob. The LERR could reflect the dynamic process of energy release, transfer and dissipation which provided an important reference for the study of the stability of deep mined out area.

• The Korean Journal of Applied Statistics
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• v.13 no.2
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• pp.247-263
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• 2000

Natural catastrophe is defined as all damages caused by natural phenomenon such as typhoon, flood, inundation, windstorm, tidal wave, tremendous snowfall, drought,earthquake and to on It is classified at a huge hazard because of the large severity ofdamage In Korea, Fire Insurance policy includet the coverage clauses and rates of naturalcatastrophe like'Flood , Inundation Coverage Clause'and'Earthquake Coverage Clause'These clauses and rates do not reflect accurate risk of flood, inundation and earthauakein Korea. because those are tariff from other countries Hence, we determine the claimsize distributions and the rates for typhoon coverage and flood-inundation coverage byusing statistical methods which have not been used so far in Korean non-life insurance,and calculate appropriate premium for policyholder's interest

• The Journal of the Korea Contents Association
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• v.16 no.12
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• pp.539-550
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• 2016

The news coverage of Sewol Ferry catastrophe has reprimanded from numbers of people because of false reports and mediamorphosis such as distorted news. Thus, the purpose of this study is to examine the news coverage of television news programs about the Sewol Ferry catastrophe. Specifically, this study was conducted to figure out problems with the disaster news reports of several broadcasting stations such as, KBS, MBC, SBS and JTBC. Furthermore, the study also explores about how they reported without following the rules of disaster news coverage and policy of disaster news coverage by content analysis.

• BMB Reports
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• v.39 no.1
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• pp.9-15
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• 2006

To prove whether error catastrophe /lethal mutagenesis is the primary antiviral mechanism of action of ribavirin against foot-and-mouth disease virus (FMDV). Ribavirin passage experiments were performed and supernatants of $Rp_1$ to $Rp_5$ were harvested. Morphological alterations as well as the levels of viral RNAs, proteins, and infectious particles in the BHK-21 cells infected using the supernatants of $Rp_1$ to $Rp_5$ and control were measured by microscope, real-time RT-PCR, western-blotting and plaque assays, respectively. The mutation frequency was measured by sequencing the complete P1- and 3D-encoding region of FMDV after a single round of virus infection from ribavirin-treated or untreated FMDV-infected cells. Ribavirin treatment for FMDV caused dramatically inhibition of multiplication in cell cultures. The levels of viral RNAs, proteins, and infectious particles in the BHK-21 cells infected were more greatly reduced along with the passage from $Rp_1$ to $Rp_5$, moreover, nucleocapsid protein could not be detected and no recovery of infectious virus in the supernatant or detection of intracellular viral RNA was observed at the $Rp_5$-infected cells. A high mutation rate, giving rise to an 8-and 11-fold increase in mutagenesis and resulting in some amino acid substitutions, was found in viral RNA synthesized at a single round of virus infection in the presence of ribavirin of $1000\;{\mu}M$ and caused a 99.7% loss in viral infectivity in contrast with parallel untreated control virus. These results suggest that the antiviral molecular mechanism of ribavirin is based on the lethal mutagenesis/error catastrophe, that is, the ribavirin is not merely an antiviral reagent but also an effective mutagen.