• Title/Summary/Keyword: case-controlled study

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A Review of the Domestic Study Trends on Climacteric Syndrome Treated with Pharmacopuncture (갱년기 증후군의 약침 치료에 대한 국내 연구 동향 고찰)

  • Hwang, Hyeon-Ji;Ahn, Soo-Yeon;Kim, Dong-Chul
    • The Journal of Korean Obstetrics and Gynecology
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    • v.34 no.3
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    • pp.79-95
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    • 2021
  • Objectives: The purpose of this review is to analyze the domestic study trends on climacteric syndrome treated with pharmacopuncture. Methods: We investigated the studies on pharmacopuncture for climacteric syndrome via searching 6 online databases. Results: 18 studies were selected. There were 2 case reports, 1 randomised controlled trial, and 15 animal experiments. There were 14 studies about osteoporosis, 1 study about hot flush and sweating, 1 study about abdominal obesity, 1 study about neck pain, and 1 study about learning disability and memory disorder. Nokyong was most frequently used for pharmacopuncture, followed by Honghwa. 陰谷 (KI10) was most frequently used for acupuncture point, followed by 腎兪 (BL23). Conclusions: This study shows that pharmacopuncture could be one of the effective treatments for climacteric syndrome. More well-designed clinical studies using pharmacopuncture for climacteric syndrome will be needed.

Integration of Laser Scanning and Three-dimensional Models in the Legal Process Following an Industrial Accident

  • Eyre, Matthew;Foster, Patrick;Speake, Georgina;Coggan, John
    • Safety and Health at Work
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    • v.8 no.3
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    • pp.306-314
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    • 2017
  • Background: In order to obtain a deeper understanding of an incident, it needs to be investigated to "peel back the layers" and examine both immediate and underlying failures that contributed to the event itself. One of the key elements of an effective accident investigation is recording the scene for future reference. In recent years, however, there have been major advances in survey technology, which have provided the ability to capture scenes in three dimension to an unprecedented level of detail, using laser scanners. Methods: A case study involving a fatal incident was surveyed using three-dimensional laser scanning, and subsequently recreated through virtual and physical models. The created models were then utilized in both accident investigation and legal process, to explore the technologies used in this setting. Results: Benefits include explanation of the event and environment, incident reconstruction, preservation of evidence, reducing the need for site visits, and testing of theories. Drawbacks include limited technology within courtrooms, confusion caused by models, cost, and personal interpretation and acceptance in the data. Conclusion: Laser scanning surveys can be of considerable use in jury trials, for example, in case the location supports the use of a high-definition survey, or an object has to be altered after the accident and it has a specific influence on the case and needs to be recorded. However, consideration has to be made in its application and to ensure a fair trial, with emphasis being placed on the facts of the case and personal interpretation controlled.

A Case Study of the Underwater Blasting Using Emulsion Explosives (에멀젼폭약을 사용한 수중발파 사례)

  • An, Bong-Do;Lee, Ik-Joo;Heo, The-Moon
    • Explosives and Blasting
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    • v.25 no.2
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    • pp.71-78
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    • 2007
  • In many cases of underwater blasting in South Korea, the special blasting is mainly used for deepening harbor, installing gas pipes, or well blasting to build a bridge. The procedure of well blasting is almost same with shaft blasting, but the difference is that water is filled in before blasting. In case of deepening blasting under water, the first step like drilling, arranging explosives, and wire connection is done on a barge, then the next step such as charging and tamping is accomplished under water by expert divers. Therefore, underwater blasting needs precise and exact plan before blasting. In this paper, authors would like to introduce a case of underwater blasting for deepening the Busan new port with emulsion explosives and non-electric detonators in order to get some of 8,500TEU out sized container vessels entered into the port and to make safe. Considering environment and vibration, the blasting was controlled to minimized the damage to the lighthouse nearby. It will be great help to many other blasting sites where emulsion explosives and non-electric detonators are used for underwater blasting through this case.

Regulation of Transforming Growth Factor ${\beta}1$, Platelet-Derived Growth Factor, and Basic Fibroblast Growth Factor by Silicone Gel Sheeting in Early-Stage Scarring

  • Choi, Jaehoon;Lee, Eun Hee;Park, Sang Woo;Chang, Hak
    • Archives of Plastic Surgery
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    • v.42 no.1
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    • pp.20-27
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    • 2015
  • Background Hypertrophic scars and keloids are associated with abnormal levels of growth factors. Silicone gel sheets are effective in treating and preventing hypertrophic scars and keloids. There has been no report on the change in growth factors in the scar tissue following the use of silicone gel sheeting for scar prevention. A prospective controlled trial was performed to evaluate whether growth factors are altered by the application of a silicone gel sheet on a fresh surgical scar. Methods Four of seven enrolled patients completed the study. Transforming growth factor (TGF)-${\beta}1$, platelet-derived growth factor (PDGF), and basic fibroblast growth factor (bFGF) were investigated immunohistochemically in biopsies taken from five scars at 4 months following surgery. Results In both the epidermis and the dermis, the expression of TGF-${\beta}1$ (P=0.042 and P=0.042) and PDGF (P=0.043 and P=0.042) was significantly lower in the case of silicone gel sheet-treated scars than in the case of untreated scars. The expression of bFGF in the dermis was significantly higher in the case of silicone gel sheet-treated scars than in the case of untreated scars (P=0.042), but in the epidermis, the expression of bFGF showed no significant difference between the groups (P=0.655). Conclusions The levels of TGF-${\beta}1$, PDGF, and bFGF are altered by the silicone gel sheet treatment, which might be one of the mechanisms of action in scar prevention.

Effects of weight bearing training on symmetrical weight supporting rate (체중부하 훈련이 대칭적 체중지지율에 미치는 효과)

  • Park, Joong-Suk;Lee, Suk-Min
    • Journal of Korean Physical Therapy Science
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    • v.9 no.1
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    • pp.53-59
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    • 2002
  • This study is research for effect of the involved lower limb weight bearing training on symmetrical weight supporting rate improvement by practicing involved lower limb weight bearing training of three weeks period to improve standing equilibrium problem with asymmetric weight supporting rate of hemiplegia. In result of the study, it has shown that P-value incase of involved supporting rate is lower than level of significance $\alpha$<.05 and mean improvement rate of experienced group is higher in comparison with controlled group and experienced group. In changing quantity of involved maximum supporting rate, P-value is .26 and higher than level of significance $\alpha$<.05, and so it did not show significant difference statistically. But in case of experienced group between pre and post-test, involved side supporting rate and involved side maximum supporting rate showed significant improvement in all. In comparison of relative characteristic training effect difference, it was shown that train-learning effect on case of 40-60 years old, hemorrhagic patient and standard body bun of patient is valuable, which showed significant improvement in case of paralytic side and disease period, it did not show significant difference on excercise learning effect in two above cases. In the above result, we can say that continuous weight bearing training on the involved lower limb for three weeks period help improve the involved side supporting rate of hemiplegia. Accordingly, the weight bearing training on the involved lower limb is training method that patient can easily train with simple guidance of therapists, without being special expensive equipment. Furthermore it can be helpful to establish home therapeutic plan for hemiplegia through education of a patron.

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Zolpidem Use and Risk of Fracture in Elderly Insomnia Patients

  • Kang, Dong-Yoon;Park, So-Young;Rhee, Chul-Woo;Kim, Ye-Jee;Choi, Nam-Kyong;Lee, Joong-Yub;Park, Byung-Joo
    • Journal of Preventive Medicine and Public Health
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    • v.45 no.4
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    • pp.219-226
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    • 2012
  • Objectives: To evaluate the risk of fractures related with zolpidem in elderly insomnia patients. Methods: Health claims data on the entire South Korean elderly population from January 2005 to June 2006 were extracted from the Health Insurance Review and Assessment Service database. We applied a case-crossover design. Cases were defined as insomnia patients who had a fracture diagnosis. We set the hazard period of 1 day length prior to the fracture date and four control periods of the same length at 5, 10, 15, and 20 weeks prior to the fracture date. Time independent confounding factors such as age, gender, lifestyle, cognitive function level, mobility, socioeconomic status, residential environment, and comorbidity could be controlled using the case-crossover design. Time dependent confounding factors, especially co-medication of patients during the study period, were adjusted by conditional logistic regression analysis. The odds ratios and their 95% confidence intervals (CIs) were estimated for the risk of fracture related to zolpidem. Results: One thousand five hundred and eight cases of fracture were detected in insomnia patients during the study period. In our data, the use of zolpidem increased the risk of fracture significantly (adjusted odds ratio [aOR], 1.72; 95% CI, 1.37 to 2.16). However, the association between benzodiazepine hypnotics and the risk of fracture was not statistically significant (aOR, 1.00; 95% CI, 0.83 to 1.21). Likewise, the results were not statistically significant in stratified analysis with each benzodiazepine generic subgroup. Conclusions: Zolpidem could increase the risk of fracture in elderly insomnia patients. Therefore zolpidem should be prescribed carefully and the elderly should be provided with sufficient patient education.

A Case Study on the Improvement of Nonelectronic Records Management System for University Archive (대학기록관의 비전자기록관리시스템 개선사례 연구)

  • Jang, Hyun-Jong;Lee, Eun-Ju
    • Journal of Korean Society of Archives and Records Management
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    • v.22 no.3
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    • pp.143-150
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    • 2022
  • With the enactment of the "Public Records Management Act" in 1999 and its revision in 2020, a records management system was established in the domestic public institutions. However, as the focus is on the management of public records, there are difficulties in managing the historical records of the university archives controlled by the nonelectronic records management system. To overcome these difficulties, this study looked at the case of Pusan National University Archives, which attempted to improve the function of the nonelectronic records management system using the "University Innovation Support Project." In particular, it is a case in which the function of the nonelectronic records management system was improved, catalogs reflecting the characteristics of resources were produced, and then the shelves were organized. It is hoped that the improvement of the nonelectronic records management system in Busan National University Archives will provide a positive direction for related organizations facing similar difficulties in the future.

A Review of Acupuncture Treatment Methods for Polycystic Ovary Syndrome (다낭성난소증후군의 침 치료법에 대한 고찰)

  • Ji-Ha Bak;Su-Ji Choi
    • The Journal of Korean Obstetrics and Gynecology
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    • v.37 no.2
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    • pp.75-108
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    • 2024
  • Objectives: The purpose of this study is to review the acupuncture treatment for Polycystic ovary syndrome (PCOS) in women. Methods: We searched articles in 3 search engines with keywords related to 'Polycystic ovary syndrome', 'PCOS', and 'Stein-leventhal' in February 2024. Clinical researches and case reports that used acupuncture on PCOS were included. Animal studies and non clinical data were excluded. Data on acupuncture treatment such as methods, site, duration, frequency, and period were analyzed. Results: Of 60 selected articles, there were 51 randomized controlled trials, 5 clinical trials and 4 case reports. Studies were conducted using manual acupuncture, electro acupuncture, auricular acupuncture, thread embedding acupuncture, warm needling and laser acupuncture. Most studies used more than one acupoint, and there were 78 acupoints selected for acupuncture treatment for PCOS. The most commonly used acupoint was 三陰交 (SP6)(n=50). By analyzing the network of acupoints, 關元 (CV4), 氣海 (CV6), 中脘 (CV12), 三陰交 (SP6), 血海 (SP10), 天樞 (ST25), 足三里 (ST36) were located in center of the network. The mean treatment time, number of treatments, and duration were 28.63±4.48 minutes, 34.52±29.26 times, and 98.18±38.25 days. Conclusions: The results of this study could be useful in establishing the evidence for performing standardized acupuncture treatment for Polycystic ovary syndrome.

A Review of Clinical Research Trends in the Treatment of Primary Headache Disorders with Pharmacopuncture (일차성 두통의 약침 치료에 대한 임상연구 동향)

  • Shin, Hee-yeon;Lee, Sang-hwa;Kim, Ha-ri;Kim, Jeong-hwa;Yang, Seung-bo;Cho, Seung-yeon;Park, Jung-mi;Ko, Chang-nam;Park, Seong-uk
    • The Journal of Internal Korean Medicine
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    • v.39 no.6
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    • pp.1191-1205
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    • 2018
  • Objectives: This study was performed to review clinical research trends in the treatment of primary headache disorders with pharmacopuncture. Methods: We searched clinical studies on primary headache disorders treated with pharmacopuncture in four electronic databases including OASIS, RISS, CNKI, and Pubmed. The selected studies were analyzed with regard to study design, subject, intervention, evaluation, and result. Results: Five randomized controlled trials, one non-randomized controlled trial, one before-and-after study, and six case series were selected. Most of the studies showed that pharmacopuncture treatment was significantly effective in treating primary headache disorders; however, the quality of the randomized controlled trials was low. Conclusions: According to this study, pharmacopuncture could be a useful treatment option for primary headache disorders. Based on these results, further studies on the effectiveness and safety of pharmacopuncture for primary headache disorders should be performed in the near future.

A Review of Clinical Studies for Treatment of Multiple System Atrophy Using the CNKI Database (다계통 위축증의 치료에 대한 임상연구 동향 - CNKI검색을 중심으로)

  • Kim, Min-ji;Won, Seo-young;Kim, Hae-yoong;Ryu, Ju-young;Jung, Eun-sun;Yoo, Ho-ryong;Seol, In-chan;Kim, Yoon-sik
    • The Journal of Internal Korean Medicine
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    • v.41 no.4
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    • pp.612-623
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    • 2020
  • Objectives: The aim of this research was to investigate and review the trends in recent clinical studies of multiple system atrophy (MSA) in China. Methods: We searched for clinical studies discussing Oriental medicine-based treatments for MSA in the China National Knowledge Infrastructure (CNKI) database. The search focused on the authors; publication year; type of study; method and duration of treatment; evaluation criteria; and results of the selected articles. Results: Among the articles retrieved from the database, eight case series, two randomized controlled trials (RCTs), and one non-randomized controlled trial (nRCT) were analyzed. Eight articles used acupuncture; ten used herbal medicine. The most frequently used acupoints were GV20, GV24, GB20, PC6, Hyeopcheok Acupoint, CV4, EX-HN3, and GV17. Jihwangeumja was the most commonly used herbal prescription. All 13 studies confirmed the efficacy of Oriental medicine treatments. Conclusions: More varied and scientifically designed clinical studies are required to develop treatments for MSA. The results of this study may provide guidance for further studies of MSA.