• Korean Journal of Exercise Nutrition
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• v.25 no.1
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• pp.1-6
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• 2021

[Purpose] We determined the effect of partial sleep deprivation (PSD) after an exercise session on exercise performance on the following morning. [Methods] Eleven male athletes performed either a normal sleep trial (CON) or a PSD trial. On the first day (day 1), all subjects performed an exercise session consisting of 90 min of running (at 75% ${\dot{V}}O_{2max}$) followed by 100 drop jumps. Maximal strength (MVC) was evaluated before and after exercise. In the CON trial, the sleep duration was 23:00-7:00, while in the PSD trial, the sleep duration was shortened to 40% of the regular sleep duration. On the following morning (day 2), MVC, the metabolic responses during 20 min of running (at 75% ${\dot{V}}O_{2max}$), and time to exhaustion (TTE) at 85% ${\dot{V}}O_{2max}$ were evaluated. [Results] On day 2, neither the MVC nor ${\dot{V}}O_2$ during 20 min of running differed significantly between the two trials. However, the respiratory exchange ratio was significantly lower in the PSD trial than in the CON trial (p = 0.01). Moreover, the TTE was significantly shorter in the PSD trial than in the CON trial (p = 0.01). [Conclusion] A single night of PSD after an exercise session significantly decreased endurance performance without significantly changing muscle strength or cardiopulmonary response.

• Journal of Veterinary Clinics
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• v.30 no.6
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• pp.421-427
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• 2013

There are many intramuscularly injectable drugs commonly used for anesthesia in dogs and combination of drugs were used for decrease the side effects. The objective of this study was to evaluate the anesthetic and cardiopulmonary effects of butorphanol-tiletamine-zolazepam-medetomidine and tramadol-tiletamine-zolazepam-medetomidine in dogs. Ten healthy beagle dogs (intact male; mean body weight : $9.5{\pm}1.60$ kg) were used in the study. Experimental animals were divided into two groups (n=5, each) and received 0.2 mg/kg of butorphanol (BZM) and 2 mg/kg of tramadol (TZM) according to the group after injection of $Zoletil^{(R)}$ (5 mg/kg) and medetomidine (10 ug/kg). All drugs were administered intramuscularly. Anesthesia and recovery, sedation and analgesia score, cardiovascular and respiratory parameters were measured. Induction and recovery time were not significantly different between the groups. Anesthesia time was $117.4{\pm}25.64$ minute and $81.2{\pm}12.50$ minute in BZM and TZM groups, respectively. Sedation and analgesia were satisfied in both groups. In both groups, common side effects related to the medetomidine, significant bradycardia and hypertension were not observed. There were no significant changes in respiratory data. In conclusion, tiletamine-zolazepam-medetomidine in combination with either butorphanol or tramadol can be suitable anesthetic protocol for minor procedures in dogs. They produced adequate anesthesia characterized by rapid induction, adequate analgesia and muscle relaxation without remarkable side effects.

• The Korean Journal of Physiology
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• v.20 no.2
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• pp.279-288
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• 1986

In an attempt to observe the to long-term training effects, the exercise of rope-skipping was regularly loaded to nine soldiers for nine weeks. And some physical characteristics, cardiopulinonary functions. some blood constituents were measured before, during and after the load of test exercise. treadmill running, and were compared with the pre-trained values. The results obtained were as follows: 1) Body weight, body surface area, skinfold thickness and total body fat decreased sifnificantly after the training. 2) The post-trained values of MVV and $FEF_{25%}$, increased significantly. 3) By the training, heart rates decreased very significantly in the resting, exercising and recovery periods. 4) After the training, the systolic blood pressures of the resting and recovery periods decreased meaningfully, while diastolic blood pressures increased significantly through the recovery stages. 5) In spite of the training, the respiration rates never change in both the resting and the recovery periods. 6) After the training, total cholesterol concentration of the venous blood decreased significantly in the resting the early recovery phases while the blood levels of glucose and HDL-cholesterol decreased very slightly. 7) Blood lactate concentration decreased through the recovery periods and the value of the recovery 20 and 60 minutes decreased obviously, in comparison with the pre-trained values. The above results suggest that the 9 week-training of the rope-skipping brings about the decrease of the body fat contents, the enhancement of cardiopulmonary functions and some changes in the blood constituents.

• Journal of Chest Surgery
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• v.6 no.2
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• pp.131-142
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• 1973

Studies of cardiopulmonary function and acid-base balance were performed on 29 dogs during control period, during oligemic hypotension and following return of blood to the animals. Intravenous morphine and local anesthesia were used. Fifteen of the 29 animals survived the complete experiment. The 14 animals that failed to survive the experimental period died between 15 to 90 minutes after the onset of bleeding. The results were as follows. 1. The heart rate increased after the onset of bleeding and failed to return to control level following reinfusion. Stroke volume decreased markedly after bleeding and failed to recover after return of blood from the reservoir. Cardiac output also decreased during oligemic hypotension and was maintained at this level after re-infusion. Total peripheral resistance decreased significantly immediately after bleeding, however it increased soon over the pre-bleeding level. Central venous pressure decreased after the onset of bleeding and remained at lower level for the rest of the experimental period. Arterial blood pressure, clown to 40-45 mmHg by acute hemorrhage, was elevated near to control level. Left ventricular work decreased tremendously during oligemic hypotension and failed to return to control level with the re-infusion of blood. Hematocrit value showed no significant decrease after bleeding and increased after re-infusion. Hemoglobin decreased after the onset of bleeding and recovered to control value after re-infusion. 2. The respiratory rate fell rapidly after bleeding from 124 to 29 and remained at this lower level for the remainder of the experiment. The tidal volume increased after bleeding and was maintained at this level for the remainder of the experiment. The respiratory minute volume showed no significant changes throughout the experimental period. Oxygen consumption fell lightly in all animals during oligemic hypotension and returned to normal levels following re-infusion. Arterial oxygen content and arterial oxygen saturation decreased following bleeding and the values returned to normal levels after the return of blood from the reservoir The arterio-venous oxygen difference increased after the onset of bleeding. It failed to return to normal values following re-infusion. Arterial $Pco_2$ decreased in all animals after the beginning of the bleeding. Partial pressure of $Co_2$ continued to fall until re-infusion, after which the values returned toward normal. Animals became acidotic. The pH fell to lower level following bleeding. Lactic acid and lactate: pyruvate ratio also increased during same period. Arterial pH and lactic acid failed to return to control value and lactate: pyruvate ratio increased more after re-infusion. Sodium bicarbonate decreased after bleeding and returned to control value following re-infusion.

• Journal of Yeungnam Medical Science
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• v.14 no.2
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• pp.350-358
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• 1997

We studied the effects of adding a single bolus(500 mg) of sodium thiopental to a continuous infusion of low-dose fentanyl on plasma beta-endorphin immunoreactivity(iBE) responses to cardiopulmonary bypass(CPB) in 28 patients undergoing elective coronary artery bypass grafting or valve procedures. Thiopental was injected just prior to the initiation of CPB. The iBE levels and the hemodynamic indices such, as mean arterial pressure, cardiac output and systemic vascular resistance were measured before CPB, at 30 min and again at 60 min after the initiation of the bypass. The results were as follows. After the initiation of CPB, iBE levels increased at 30 min and 60 min(P=0.006, P=0.004 respectively) in the control group, but not in the thiopental group. There were significant differences in the changes of iBE levels between the groups(F=8.7, G-G=0.002, P=0.001). The hemodynamic indices were similar in both groups. In conclusion, pretreatment with thiopental just before the initiation of CPB prevents the stress-induced beta-endorphin response to CPB.

• Journal of Life Science
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• v.17 no.4 s.84
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• pp.515-521
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• 2007

Aprotinin, a serine protease inhibitor, has been used to ameliorate the inevitable consequences, including blood component injury after cardiac surgery with cardiopulmonary bypass (CPB). However, there are many arguments on its dosage or usage. We assessed whether administration of low dose of aprotinin in only priming solution has any beneficial effect or reduces its side effects on cardiac surgery. Thirty patients scheduled for elective cardiac surgery were randomly assigned to aprotinin group (n=15) which received aprotinin in priming solution (two million kallikrein inhibitory unit, KIU) and added one million KIU at 1 hour after the beginning of CPB or control group (n=15) which did not receive it. Hematological and biochemical variables, cytokines and cardiac marker levels, and postoperative outcomes were compared between two groups at before, during or after operation. Platelet count in aprotinin group was higher than that of control group at postoperative 24 hr. Activated partial thromboplastin time in aprotinin group was longer than that of control group at intensive care unit (ICU). Troponin-I level and postoperative blood loss volumes in aprotinin group were lower than those of control group at ICU. There were no significant differences between the two groups on the others. These results showed that low dosage of only priming solution during cardiac surgery with CPB reduced platelet destruction and postoperative bleeding, and attenuates myocardial damage. However, further studies need to be carried out with more population or pediatric patients for evaluating various aprotinin usage.

• Korean Journal of Health Education and Promotion
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• v.23 no.4
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• pp.155-171
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• 2006

Objective: The purpose of this study was to apply the Basic CPR(Cardiopulmonary resuscitation) training education program and identify its effects on knowledge of Basic CPR and skills of Basic CPR in second grade high school students. Methods: The training program was conducted for 16 weeks between March 26 and July 9, 2005 using a non-equivalent control group pretest-post test design by dividing 60 students in a half for both the experimental group and the control group. General characteristics, the effect of the education were evaluated with $x^2-test$, t-test, ANCOVA, Repeated Measure ANOVA and Bonferonni with SPSS 11.0/pc. Result: After the CPR education program application, knowledge score in the experimental group increased to 20.57 right after the education from 9.32, the score measured before the training, 19.11 after 8 weeks and 18.29 after 12 weeks. On the contrary, the control group's score showed no significant before the training. According to the result of knowledge score comparison between the experimental and control group at each point in time, the experimental group had a significantly high score in knowledge at every point(p<0.001). In the effect durability for knowledge of the training education program in process time after the training program in the experimental group, the durability of effect was identified despite the elapsing time. Scores of skills for Basic CPR increased from 1.21, the score measured before the training program, to 30.07 right after the education, 23.50 after 8 weeks and 17.57 after 12 weeks in experimental group. On the contrary, the control group showed an immaterial increase. According to the result of skill score comparison between the experimental and control group at each point in time, the experimental group had a significantly high score in skill at every point(p<0.001). The score for skill increased significantly right after the education compared to the score prior to the education. Conclusions: These findings suggest that Basic CPR training education program facilitate knowledge of CPR and skill of CPR in high school students. Therefore, it would be necessary to include the Basic CPR training program in high school education curriculum. However, the effect of Basic CPR knowledge maintains for a few period, and the effect of maintaining the skill is shorter than the maintenance of knowledge so regular reeducation is considered to be needed.

• The Journal of the Korea Contents Association
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• v.13 no.4
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• pp.320-330
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• 2013

The purpose of this study is to increase efficiency of CPR through comparing the chest-compression quality between rescuer's simplified verbal order method and the continued verbal order method by utilizing voice meter during CPR. Subjects were 89 people(45 people for the experimental group, 44 people for the control group) who completed the 15-week CPR curriculum as undergraduates for the department of Emergency Medical Technology in C Province and were carried out by being randomly extracted. The group division was set for the experimental group as the group with the simplified verbal order and for the control group as the group with the continued verbal order. The period of measurement was progressed primarily(November 10, November 28, 2011) and secondarily(September 3-September 4, 2012). An analysis was used SPSS WIN 12.0 program. As a result of research, as for the implementation of appropriate chest compression(time, %), the quality was higher(p<.05) in the experimental group(102.86 times, 67.79%) than the control group(85.31 times, 55.84%). As a result of research, the chest compression(time, %) in the experimental group(102.86 times, 67.79%) had the higher effect of chest compression quality(p<.05) than the control group(85.31 times, 55.84%). On the other hand, the operation of weak chest compression(time) was higher in control group(61.13 times) than experimental group(35.54 times). The proper chest compression was shown(p<.05) in men of the experimental group as for gender and in over 60kg of the experimental group as for weight.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.9
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• pp.4437-4446
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• 2013

The purpose of this study was to development and evaluate the effects of cardiocerebrovascular disease prevention program for taxi drivers on physiological variables(blood pressure, blood sugar, serum lipids) and physical variables(body fat, muscle endurance, cardiopulmonary endurance, balance). This study consisted of two phases: developing the program and evaluating its effectiveness. 1 phase, 321 taxi drivers investigated a health condition and a life habit and an educational need and developed a program with the ground which will reach. 2 phases, The effectiveness of the program was tested in October 2011, with 51 taxi driver. The experimental group was given 12 weeks period exercise 1 weeks 3 time, disease education 4 time, 2 nutrition consultations. Although there was no significant reduction in blood pressure, heart rate, blood sugar, serum lipids, there were statistically significant increases in muscle endurance (t=-7.62 p<.001), cardiopulmonary endurance (t=-3.39, p<.001), balance(t=-4.13, p<.001) and decreased body fat (t= -3.11, p<.015) in before compared to after. These findings suggest that an integrated cardiocerebro-vascular disease prevention program improves physical fitness.

• Journal of Chest Surgery
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• v.15 no.1
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• pp.61-66
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• 1982

The present study was performed to evaluate hemodynamic effects on the pericardial patch graft for stenosis of right ventricle outflow tract in 19 patients of tetralogy of Fallot. The stenosis of right ventricle outflow tract was associated with or without pulmonary annular nar-rowing, pulmonary valvular stenosis, and hypoplastic narrowing of pulmonary artery. Total correction of tetralogy of Fallot was performed under cardiopulmonary bypass with moderate hypothermia and cardioplegic cardiac arrest. Ventricular septal defects were closed with Teflon patch graft. The chamber pressures in the heart were measured before and after a total correction of tetralogy of Fallot. The data of pressure measurement and the results of postoperative observation of pericardial patch were as followings: 1. Systolic and diastolic pressure of right ventricle was decreased after operation from $96.0{\pm}14.7/10.0{\pm}14.4mmHg$ to $61.0{\pm}13.1/8.0{\pm}9.3mmHg$. 2. Systolic and diastolic pressure of pulmonary artery was increased after operation from $18.0{\pm}5.6/10.0{\pm}5.5mmHg$ to $31.0{\pm}10.7/14.0{\pm}4.9mmHg$. 3. Preoperative pressure gradient between right ventricle and pulmonary artery was decreased immediately after operation from 78.0mmHg to 30.0mmHg. 4. It was observed that excellent widening effects of right ventricle outflow tract was resulted from pericardial patch graft. 5. No postoperative bleeding from pericardial patch graft was observed. 6. Aneurysm formation of pericardial patch was not be observed during 1 to 6 years postoperative periods.