• Journal of Chest Surgery
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• 제27권8호
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• pp.650-655
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• 1994

The author analyzed 99patients with VSD weighting less than 10kg of body weight who underwent surgical correction from 1981 to 1992 at cardiovascular department of Hanyang University hospital. Patients occupied 29.3% of total cases who were underwent surgical corrections for congenital heart diseases during that time. Of the 99 patients, 51 patients were male [52%] and 48 patients[48%] were female. Age ranged from 28 days to 36 months with mean age of 13.6 months. Mean body weight was 7.53kg. According to Kirklin`s anatomical classification, type II defect was most common [61.6%]. Associated anomaly was found in 48 patients [48.5%]. Patent foramen ovale was most commonly associated cardiac anomaly [14.1%] and followed by atrial septal defect [12.1%], patent ductus arteriosus [10.1%]. Cardiac catheterization data were analyzed. The most common range of Qp/Qs, Rp/Rs, Pp/Ps were above 3.0, 0.1 - 0.25, and above 0.75 respectively. Among the indications of surgical correction, there were pulmonary hypertention in 69 patients, congestive heart failure in 44 patients, frequent respiratory infection in 47 patients, growth retardation in 33 patients. The most common surgical approach and method for VSD closure were right atriotomy[48.3%] and dacron patch closure[93.3%]. Complication rate was 13.1% [13 cases], and overall mortality was 17.1% [17 cases]. The cause of death consisted of low cardiac output syndrome[11 cases], acute renal failure[3 cases], sepsis[2 cases] and pulmonary insufficiency[1 case] in order of frequency.

• International Journal of Control, Automation, and Systems
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• 제1권3호
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• pp.368-375
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• 2003

Data fusion approach is investigated to avoid suction in the left ventricular assist system (LVAS) using a nonpulsatile pump. LVAS requires careful control of pump speed to support the heart while preventing suction in the left ventricle and providing proper cardiac output at adequate perfusion pressure to the body. Since the implanted sensors are usually unreliable for long-term use, a sensorless approach is adopted to detect suction. The pump model is developed to provide the load coefficient as a necessary signal to the data fusion system without the implanted sensors. The load coefficient of the pump mimics the pulsatility property of the actual pump flow and provides more comparable information than the pump flow after suction occurs. Four signals are generated from the load coefficient as inputs to the data fusion system for suction detection and a neural fuzzy method is implemented to construct the data fusion system. The data fusion approach has a good ability to classify suction status and it can also be used to design a controller for LVAS.

• Journal of Chest Surgery
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• 제22권4호
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• pp.687-692
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• 1989

Aneurysm of the sinus of Valsalva is an uncommon cardiac anomaly, usually congenital in origin, which may occur as an isolated defect or in conjunction with other cardiac malformation. This report is a case of a ruptured sinus of Valsalva aneurysm with ventricular septal defect in a 18-year-old female patient who complained progressive exertional dyspnea. She underwent operative management using total cardiopulmonary bypass. The fistula originated from the right coronary sinus and ruptured into the right ventricle and coexistent lesion was supracristal ventricular septal defect. The repair was done through aortic and right ventricular approach. The ruptured sinus of Valsalva was closed with pledget suture and the ventricular septal defect was closed with patch. The postoperative result was good.

• Journal of Chest Surgery
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• 제18권1호
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• pp.62-68
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• 1985

10 patients with mitral regurgitation associated with various congenital cardiac anomalies were treated by reconstructive techniques in the Department of Thoracic and Cardiovascular Surgery, Hanyang University Hospital during the period of 2 years from 1982 to 1984. There were mitral valvular cleft in one case, chordae tendineae rupture associated with congenital multiple cardiac-anomalies [VSD, PDA, prolapse of aortic non-coronary cusp through VSD] in one case, elongated chordae tendineae after removal of left atrial myxoma in one case, and mitral annular dilatation associated with VSD in 3 cases, large PDA in 2 cases, aortic regurgitation [bicuspid valve] in one case, and unknown origin in one case. Owing to the various pathology above mentioned, reconstructive surgical approach to mitral incompetence is accordingly complicated and a combination of the following different procedures were properly used case by case, that is, suture of chordae tendineae, shortening of elongated chordae tendineae, closure of VSD, ligation of PDA, aortic valvuloplasty, mitral annuloplasty with mattress suture, etc. All patients were survived and they have been excellent postoperative results.

• Journal of Chest Surgery
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• 제53권6호
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• pp.403-407
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• 2020

To validate the technique of the single Heartstring aortotomy for multiple off-pump venous bypass grafts (described in 2015), the results of a 38-month follow-up study of 18 patients, including high-risk patients, are presented. No early deaths or cardiac or cerebral complications occurred. During the follow-up period, 2 patients died of non-cardiac causes, and 3 developed coronary ischemia. Ischemia occurred due to late graft occlusion in 2 patients, both of whom had normal postoperative courses and correct graft flow. The presence of acute symptoms 24 months after surgery in these patients indicated that technical graft failure was unlikely. This safe technique combines the advantages of simple and reproducible revascularization, the off-pump approach, and minimal aortic manipulation.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.212-213
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• 2002

Using the isolated perfused rat heart this study investigated 1) the cardiac uptake of idarubicin (IDA), 2) the role of P-glycoprotein (P-gp) in the uptake process, 3) the formation of IDOL from IDA in the heart, and 4) the effect of P-gp inhibitors (verapamil, amiodarone, PSC 833), doxorubicin, hypothermia, xanthine derivatives (caffeine, theophylline) and metabolism inhibitors (rutin, phenobarbital) on the pharmacokinetics and pharmacodynamics of IDA using a mathematical modeling approach. A minimal model was constructed; the differential equations were numerically solved and fitted to the data using the ADAPT II-software package using maximum likelihood estimation assuming that the measurement error has a standard deviation which is a linear function of the measured quantity［1］. (omitted)

• Journal of Chest Surgery
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• 제23권6호
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• pp.1168-1173
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• 1990

From 1981 to 1990, we performed operation on 6 patients with cardiac myxomas, which were located in the left atrium in 5, in the biatrium in 1. There were 3 male and 3 female patients ranging in age from 13 years to 69 years. Symptoms included exertional dyspnea, palpitation and signs of systemic illness. Diagnosis was accomplished by angiography[3 patients] and echocardiography [3 patients]. In all cases, myxomas were excised successfully through incision of interatrial septum There were no operative deaths or intraoperative embolic episode. Follow-up has been 40.0\ulcorner40.6 months[ranging from 1 month to 9 years], results of each patient were excellent We suggested that excision of intracardiac myxomas is curative and follow-up results are excellent. The transseptal approach provides adequate exposure and allows complete removal of the tumor regardless of its location.

• 대한치과의사협회지
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• 제53권8호
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• pp.538-544
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• 2015

In a dental treatment, a dentist has to know the possibility to happen all kinds of the emergency and to prepare for managing that situation. Especially, the cardiac arrest is the most serious emergent problem. If the accident were happened, most dentists got embarrassed. The American Heart Association (AHA) is offering the Basic Life Support (BLS), Advanced Cardiopulmonary Life Support (ACLS) and Pediatric Advanced Life Support (PALS) programs for the healthcare who need to prepare the life threatening situation. The PALS is specialized to someone who participate in pediatric health-care field. This program is composed of three major emergency problems, such as respiratory emergencies, shock and cardiac arrests. The main concepts of the PALS are early recognition and systemic team approach. The purpose of this study was to introduce about PALS and to prepare response system for emergencies in the dental environment.

• Journal of Chest Surgery
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• 제52권5호
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• pp.372-375
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• 2019

A 55-year-old man was admitted to the trauma center after a car accident. Cardiac tamponade, traumatic aortic injury, and hemoperitoneum were diagnosed by ultrasonography. The trauma surgeon, cardiac surgeon, and interventional radiologist discussed the prioritization of interventions. Multi-detector computed tomography was carried out first to determine the severity and extent of the injuries, followed by exploratory sternotomy to repair a left auricle rupture. A damage control laparotomy was then performed to control mesenteric bleeding. Lastly, a descending thoracic aorta injury was treated by endovascular stenting. These procedures were performed in the hybrid-angio room. The patient was discharged on postoperative day 135, without complications.

• Journal of Chest Surgery
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• 제31권3호
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• pp.255-261
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• 1998

영남대학교 흉부외과학교실에서는 93년7월부터 95년 5월까지 흉부 둔상에 의한 심장파열로 발생한 심장압전 환자에서 다음과 같은 결과를 얻었다. 남녀비는 10:1로 남자가 절대적으로 많았으며, 평균 41세로 주로 활동하는 젊은 남자였다. 원인은 대부분 환자가 교통사고에 의해서 발생하였으며 압박사고와 추락에 의한 경우가 각 1례씩이었다. 수상후 내원까지는 평균 139분이 소요되었으나 그 중 다른 병원을 거쳐서 내원한 경우는 비교적 많은 227분이 소요되었고, 내원후 수술 까지는 평균 117분이 소요되었으며, 수술 지연시간은 평균 25분이었다. 발생부위는 우심실이 2례, 우심방이 5례 좌심실이 2례, 좌심방이 1례로서 확인되지 않은 1례를 제외하고 우측 심장에서 더 많이 발생하였다. 내원시 호소하는 증상으로는 호흡곤란, 흉통과 오심 및 구토이 많았으며, 대다수의 환자들이 특징적인 심장압전의 증상을 나타냈다. 수술은 정중 흉골절개를 통한 직접 봉합이 대부분이었으나 직접 봉합이 어려웠던 1례에서는 심폐기를 사용하여 시행되었고 1례를 제외한 전례에서 양호한 결과를 얻을 수 있었다.