• 한국동물위생학회지
• /
• 제16권2호
• /
• pp.127-137
• /
• 1993

Carbon tetrachloride ($CCl_4$) has been used to treat a variety of parasitic infection in both large and small animals, including Fasciola hepatica. Recently, we can easily contest with carbon tetrachloride in air, food, water, rain and Industry area etc. and it is using in order to induce liver injury in laboratory. In this study. we investigated activitis of LDH, ALP, AST and ALT and amount of cholesterol, triacylglycerol, glucose and BUN in mice serum exposed to $CCl_4.$ The mice divided Into a Naive control(A), corn oil control(B) and experimental group(C, D). Naive control group(A) was given feed and water only. Corn oil control group(B) was given corn oil 1ml /100g of body weight(B.W). Experimental group(C) was given carbon tetrachloride 1ml /100g B.W. ($CCl_4$： corn oil=1：20(V /V) ), Experimental group(D) was given carbon teterachloride 1ml /100g B.W. ($CCl_4$: corn oil=1：10(V /V) ). The results obtained were summarized as follows : 1) The body weight was declined after the l0th day In mice exposed to carbon tetra-chloride. 2) The total protein level in serum was significantly in mice exposed to carbon tetra-chloride($P{\leq}0.05$). The albumin and A /G ratio was decresed significantly in mice exposed to carbon tetrachloride($P{\leq}0.01$) 3) All of the activity of LDH, AST, ALT and ALP in mice serum exposed to carbon tetra chloride inclosed significantly activity of LDH ($P{\leq}0.05$), inclosed significantly activity of AST($P{\leq}0.05, \;p {\leq}0.01$), inclosed significantly activityof ALT 3nd ALP($P {\leq}0.05,\;p {\leq}0.01$). 4) The amount of cholesterol and triacylglycerol, lipid metabolite products in serum was inclosed in case of cholesterol but did not change in case of triacylglycerol.

• 약학회지
• /
• 제43권5호
• /
• pp.572-576
• /
• 1999

The root of Polygonum cuspidatum (Polygonaceae) has been used as treatments of hyperlipidemia, dermatitis, gonorrhea, favus athlete's foot, inflammation in traditional medicine. In order to examine anti-lipidperoxidation activity, hexane, EtOAc, BuOH and water fractions of its methanol extract were administered to carbon tetrachloride intoxicated rats. Ethylacetate fraction exhibited antilipidperoxidative effect on liver lipid homogenate and the radical scavenging effect on DPPH. Serum transaminase, AlP, triglyceride and total cholesterol contents significantly decreased by administrations of ethylacetate fraction.

• Carbon letters
• /
• 제13권2호
• /
• pp.109-114
• /
• 2012

A nuclear, biological, chemical (NBC) canister was indigenously developed using active carbon impregnated with ammoniacal salts of copper (II), chromium (VI) and silver (I), and high efficiency particulate aerosol filter media. The NBC canister was evaluated against carbon tetra chloride ($CCl_4$) vapours, which were used as a simulant for persistent chemical warfare agents under dynamic conditions for testing breakthrough times of canisters of gas masks in the National Approval Test of Respirators. The effects of $CCl_4$ concentration, test flow rate, temperature, and relative humidity (RH) on the breakthrough time of the NBC canister against $CCl_4$ vapour were also studied. The impregnated carbon that filled the NBC canister was characterized for surface area and pore volume by $N_2$ adsorption-desorption isotherm at liquid nitrogen temperature. The study clearly indicated that the NBC canister provides adequate protection against $CCl_4$ vapours. The breakthrough time decreased with the increase of the $CCl_4$ concentration and flow rate. The variation in temperature and RH did not significantly affect the breakthrough behaviour of the NBC canister at high vapour concentration of $CCl_4$, whereas the breakthrough time of the NBC canister was reduced by an increase of RH at low $CCl_4$ vapour concentration.

• 한국세라믹학회지
• /
• 제45권3호
• /
• pp.150-156
• /
• 2008

Pitch-binded activated carbon fiber(ACF)/$TiO_2$ composite photocatalysts were prepared by Carbon Tetra Chloride (CTC) solvent mixing method with different mixing ratios of anatase to ACF. The result of the textural surface properties demonstrated that there is a slight increase in the Brunauer, Emmett and Teller (BET) surface area of composites with an increase of the amount of ACF. The surfaces structure morphologies of the composites were observed using an Scanning Electron Microscope (SEM). In the XRD patterns for all ACF/$TiO_2$ composites, the diffraction peaks showed the formation of anatase crystallites. The EDX spectra showed the presence of C, O and Si with strong Ti peaks. Most of these samples were richer in carbon and major Ti metal than any other elements. From the photo-decomposition results, the excellent activity of the ACF/$TiO_2$ composites between c/$c_0$ for methylene blue and UV irradiation time could be attributed to both the effects of the photocatalysis of the supported $TiO_2$ and adsorptivity of activated carbon fiber and another carbon derived from pitch.

• 한국약용작물학회:학술대회논문집
• /
• 한국약용작물학회 2011년도 추계학술발표회
• /
• pp.244-245
• /
• 2011

• 한국임상수의학회지
• /
• 제15권2호
• /
• pp.319-324
• /
• 1998

본 연구의 목적은 개에서 사염화탄소에 의하여 실험적으로 유발된 급성 간장질환에 대 한 침술의 치료효과를 알아보는데 있다. 잡종의 성견 24두를 실험에 사용하였다. 사염화탄소 를 동량의 광유에 회석하고, 24두의 개에 kg당 2 ml을 피하로 주사하였으며, 그리고 6두는 laserpuncture로 치료하였고, 6두는 침으로 치료하였으며, 6두는 전침으로 치료하였고, 6두는 대조군으로서 처치를 안 하였다. 치료는 매일 1회씩 4일동안 실시하였다. 적용된 경혈은 간유 와 영태이었다. 침술의 치료효과는 임상증상, 혈액화학치 및 심전도에 의하여 측정되었다. 치 료후에, laserpuncture군이 다른 군들에 비하여 임상중상, 혈액화학치 및 심전도에 있어서 비 교적 빠른 회복을 나타내었다. 전침 및 침군은 대조군에 비하여 약간 빠른 회복을 나타내었다.

• 한국미생물·생명공학회지
• /
• 제19권3호
• /
• pp.308-312
• /
• 1991

B.thuringiensis subsp. darmstadiensis 73E10-2의 내독소에 대한 화학적 처리에서 고농도의 중성염(4M NaBr), 유기용매(50% acetone), 변성제(4M urea) 및 중성 계면활성제(10% triton X-100)로 내독소를 처리하였을 때 모기유충에 대한 독력의 소실이 거의 나타나지 않았으나, guanidine HCL이나 $CCl_4$ 또는 양이온 및 음이온 계면활성제로 처리함으로써 그 독력이 크게 소실되었다. 또한, 내독소의 sulfhydryl기의 변형은 모기유충에 대한 독력에 영향을 나타내지 못하였으나, lysine기 변형으로 내독소의 독력이 거의 완전히 소실되었다.

• 대한수의학회지
• /
• 제38권4호
• /
• pp.918-928
• /
• 1998

The present study was done with two aims. First, to evaluate the radiographic measurements of liver volumes in normal and hepatomegaly dogs induced by carbon tetrachloride. Second, to investigate quantitative tissue echo pattern by ultrasonography. Gray level histogram of the normal liver and the kidney were estimated with carbon tetra-chloride intoxication. In normal, r-square for liver volume to body weight was 0.93372, and this showed direct linear regression. Gray level histograms of the normal liver and the kidney were $19.150{\pm}2.490$(mean${\pm}$SD) and $13.175{\pm}2.686$(mean${\pm}$SD) respectively(p < 0.01). Liver parenchymal echogenicity was more hyperechogenic than kidney cortex echogenicity. Liver/Kidney ratio was $1.504{\pm}0.313$ and it can be used relative comparison of liver and kidney parenchymal echogenicity. In carbon-tetrachloride($CCl_4$) intoxication, changes of liver volume appeared to increase up to 24 hours after administration (p < 0.05), and decreased gradually to normal level after 2~5 days. Gray level histogram of liver parenchyma decreased up to 24hours (p < 0.01) after intoxication and then gradually increased to normal level. But that of kidney cortex had no significant change. Liver/Kidney ratio also decreased by 2 days(p < 0.01) and then gradually increased to normal level. On histopathologic features of hepatic tissues in carbon tetrachloride intoxication, both coagulative necrosis of hepatic cell and hemorrhage of centrilobular & midzonal area were identified. Conclusively, plain radiography is a useful diagnostic method for evaluating liver volume in mild hepatomegaly. Especially, it is considered that an adequate numerical processing of the liver length, depth and thoracic width and depth measurement would be helpful. Using gray level histogram, ultrasonographic evaluation was useful objective methods in early diagnosis of diffuse hepatic disease.

• 한국수산과학회지
• /
• 제27권6호
• /
• pp.696-703
• /
• 1994

수산 폐기물의 효과적인 이용을 위하여 오징어 내장의 지질을 추출하여 용매를 달리하여 분리한 후 어유에 첨가하여 산화효과를 검토하였다. 오징어 내장의 주요 지방산은 팔미틴산($C_{16:0}$), 올레산($C_{18:1}$), 아이코산펜타엔산($C_{20:5}$), 그리고 도코사헥사엔산($C_{22:6}$)으로 추출용매의 종류에 따라 $64{\sim}71\%$를 차지하였으며 그 중 오메가-3 고도불포화지방산(n-3 PUFA)의 함량이 $41\%$ 이상이었다. 조지질을 정제어유에 각각 $5\%,\;1\%,\;0.5\%$ 첨가하여 $40^{\circ}C$에서 저장하면서 산화억제정도를 검토한 결과 적정농도 ($5\%$) 이하로 첨가할 경우의 효과는 미약한 것으로 나타났다. 헥산 추출물은 조지질이나 사염화탄소-메탄올추출물 보다 산화억제효과가 낮았으며 사염화탄소-메탄올(1 : 1, 1 : 3, 1 :9 v/v)추출물은 극성이 높을 수록 효과가 큰 것으로 미루어 볼 때 극성지질이 산화억제에 중요한 역할을 하는 것으로 추정할 수 있었다.

• Elastomers and Composites
• /
• 제37권1호
• /
• pp.31-38
• /
• 2002

카르복실화 스티렌-부타디엔 라텍스의 중합시간은 사용되는 부타디엔 모노머가 공액 이중결합을 가진 화학적 구조로 인하여 라디칼 중합시 홀 전파의 비편재화로 인해 아크릴 에멀젼의 제조시 보다 중합시간이 매우 길다. 또한 라텍스 자체가 고분자와 분산매의 분리 없이 사용되기 때문에 라텍스의 안정성은 대단히 중요하다. 물성의 저하없이 반응시간을 단축하기 위하여 기존에 사용하던 연쇄이동제인 사염화탄소 대신 tert-dodecylmercaptane 과 ${\alpha}$-methylstyrene dimer를 혼합 사용하여 반응시간을 14시간에서 12시간으로 줄일 수 있었다. 반응 성장단계에서 아크릴산의 투입량을 0.3 part로 제한하여 라텍스의 점도 상승을 막고 초기중합단계 직후에 아크릴아미드를 0.1 part 첨가하여 라텍스 입자의 내부영역과 외부영역의 고분자 사슬의 상호간확산을 막아 단단하면서도 접착력을 유지할 수 있는 라텍스의 합성 결과를 얻었다.