• Title/Summary/Keyword: carbon tetra-chloride

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Changes of Biochemical Composition and Activity of Enzyme in the Serum Exposed to Carbon Tetrachloride in Mice (사염화탄소를 투여한 MICE 혈청내 효소 활성 및 생화학적 조성의 변화)

  • 김순태;손재권;김상윤
    • Korean Journal of Veterinary Service
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    • v.16 no.2
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    • pp.127-137
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    • 1993
  • Carbon tetrachloride ($CCl_4$) has been used to treat a variety of parasitic infection in both large and small animals, including Fasciola hepatica. Recently, we can easily contest with carbon tetrachloride in air, food, water, rain and Industry area etc. and it is using in order to induce liver injury in laboratory. In this study. we investigated activitis of LDH, ALP, AST and ALT and amount of cholesterol, triacylglycerol, glucose and BUN in mice serum exposed to $CCl_4.$ The mice divided Into a Naive control(A), corn oil control(B) and experimental group(C, D). Naive control group(A) was given feed and water only. Corn oil control group(B) was given corn oil 1ml /100g of body weight(B.W). Experimental group(C) was given carbon tetrachloride 1ml /100g B.W. ($CCl_4$: corn oil=1:20(V /V) ), Experimental group(D) was given carbon teterachloride 1ml /100g B.W. ($CCl_4$: corn oil=1:10(V /V) ). The results obtained were summarized as follows : 1) The body weight was declined after the l0th day In mice exposed to carbon tetra-chloride. 2) The total protein level in serum was significantly in mice exposed to carbon tetra-chloride($P{\leq}0.05$). The albumin and A /G ratio was decresed significantly in mice exposed to carbon tetrachloride($P{\leq}0.01$) 3) All of the activity of LDH, AST, ALT and ALP in mice serum exposed to carbon tetra chloride inclosed significantly activity of LDH ($P{\leq}0.05$), inclosed significantly activity of AST($P{\leq}0.05, \;p {\leq}0.01$), inclosed significantly activityof ALT 3nd ALP($P {\leq}0.05,\;p {\leq}0.01$). 4) The amount of cholesterol and triacylglycerol, lipid metabolite products in serum was inclosed in case of cholesterol but did not change in case of triacylglycerol.

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Antilipoperoxidant Activity of the Root Polygonum cuspidatum on Carbon Tetrachloride Induced Hepatotoxicity (호장근의 사염화탄소로 유도된 지질과산화 저해활성)

  • 김지연;양기숙
    • YAKHAK HOEJI
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    • v.43 no.5
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    • pp.572-576
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    • 1999
  • The root of Polygonum cuspidatum (Polygonaceae) has been used as treatments of hyperlipidemia, dermatitis, gonorrhea, favus athlete's foot, inflammation in traditional medicine. In order to examine anti-lipidperoxidation activity, hexane, EtOAc, BuOH and water fractions of its methanol extract were administered to carbon tetrachloride intoxicated rats. Ethylacetate fraction exhibited antilipidperoxidative effect on liver lipid homogenate and the radical scavenging effect on DPPH. Serum transaminase, AlP, triglyceride and total cholesterol contents significantly decreased by administrations of ethylacetate fraction.

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Breakthrough behaviour of NBC canister against carbon tetrachloride: a simulant for chemical warfare agents

  • Srivastava, Avanish Kumar;Shah, D.;Mahato, T.H.;Singh, Beer;Saxena, A.;Verma, A.K.;Shrivastava, S.;Roy, A.;Yadav, S.S.;Shrivastava, A.R.
    • Carbon letters
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    • v.13 no.2
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    • pp.109-114
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    • 2012
  • A nuclear, biological, chemical (NBC) canister was indigenously developed using active carbon impregnated with ammoniacal salts of copper (II), chromium (VI) and silver (I), and high efficiency particulate aerosol filter media. The NBC canister was evaluated against carbon tetra chloride ($CCl_4$) vapours, which were used as a simulant for persistent chemical warfare agents under dynamic conditions for testing breakthrough times of canisters of gas masks in the National Approval Test of Respirators. The effects of $CCl_4$ concentration, test flow rate, temperature, and relative humidity (RH) on the breakthrough time of the NBC canister against $CCl_4$ vapour were also studied. The impregnated carbon that filled the NBC canister was characterized for surface area and pore volume by $N_2$ adsorption-desorption isotherm at liquid nitrogen temperature. The study clearly indicated that the NBC canister provides adequate protection against $CCl_4$ vapours. The breakthrough time decreased with the increase of the $CCl_4$ concentration and flow rate. The variation in temperature and RH did not significantly affect the breakthrough behaviour of the NBC canister at high vapour concentration of $CCl_4$, whereas the breakthrough time of the NBC canister was reduced by an increase of RH at low $CCl_4$ vapour concentration.

Properties and Photocatalytic Activity of Pitch-binded ACF/TiO2Composites

  • Oh, Won-Chun;Jung, Ah-Reum
    • Journal of the Korean Ceramic Society
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    • v.45 no.3
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    • pp.150-156
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    • 2008
  • Pitch-binded activated carbon fiber(ACF)/$TiO_2$ composite photocatalysts were prepared by Carbon Tetra Chloride (CTC) solvent mixing method with different mixing ratios of anatase to ACF. The result of the textural surface properties demonstrated that there is a slight increase in the Brunauer, Emmett and Teller (BET) surface area of composites with an increase of the amount of ACF. The surfaces structure morphologies of the composites were observed using an Scanning Electron Microscope (SEM). In the XRD patterns for all ACF/$TiO_2$ composites, the diffraction peaks showed the formation of anatase crystallites. The EDX spectra showed the presence of C, O and Si with strong Ti peaks. Most of these samples were richer in carbon and major Ti metal than any other elements. From the photo-decomposition results, the excellent activity of the ACF/$TiO_2$ composites between c/$c_0$ for methylene blue and UV irradiation time could be attributed to both the effects of the photocatalysis of the supported $TiO_2$ and adsorptivity of activated carbon fiber and another carbon derived from pitch.

The Studies on Treatment of Liver Disease Using Lasers and Acupuncture in Dogs (개에서 Lasers 및 침술을 이용한 간장질환 치료에 관한 연구)

  • 김명철;신상태;변흥섭;남윤이;김종만;김무강;이경렬;남치주
    • Journal of Veterinary Clinics
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    • v.15 no.2
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    • pp.319-324
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    • 1998
  • 본 연구의 목적은 개에서 사염화탄소에 의하여 실험적으로 유발된 급성 간장질환에 대 한 침술의 치료효과를 알아보는데 있다. 잡종의 성견 24두를 실험에 사용하였다. 사염화탄소 를 동량의 광유에 회석하고, 24두의 개에 kg당 2 ml을 피하로 주사하였으며, 그리고 6두는 laserpuncture로 치료하였고, 6두는 침으로 치료하였으며, 6두는 전침으로 치료하였고, 6두는 대조군으로서 처치를 안 하였다. 치료는 매일 1회씩 4일동안 실시하였다. 적용된 경혈은 간유 와 영태이었다. 침술의 치료효과는 임상증상, 혈액화학치 및 심전도에 의하여 측정되었다. 치 료후에, laserpuncture군이 다른 군들에 비하여 임상중상, 혈액화학치 및 심전도에 있어서 비 교적 빠른 회복을 나타내었다. 전침 및 침군은 대조군에 비하여 약간 빠른 회복을 나타내었다.

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Stability on Chemical Treatment of Niosquitocidal delta-endotoxin from Bacillus thuringiensis subsp. darmstadiensis 73E10-2 (모기유충에 살충력이 있는 Bacillus thuringiensis subsp. darmstadiensis 73E10-2의 delta-endotoxin의 화학적 처치에 따른 안정성)

  • 김광현;조경순;이광배
    • Microbiology and Biotechnology Letters
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    • v.19 no.3
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    • pp.308-312
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    • 1991
  • The delta-endotoxin from B. thuringiensis subsp. damstadienszs 73E10-2 was resistant to high concentration of salt (4M NaBr), organic solvents (50% acetone), denaturants (4 M urea), and neutral detergents (10% triton X-100). In contrast, the toxin was inactivated by treating with charged detergents as well as guanidine hydrochloride or carbon tetra-chloride. The delta-endotoxin is not a sulfhydryl activated toxin, but modification of the lysine side chains eliminated toxicity against mosquito larvae.

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Ultrasonographic and radiographic evaluation for the quantitative diagnosis of diffuse hepatic disease in dogs (개에서 미만성 간장병변의 정량적 진단을 위한 초음파 및 방사선학적 평가)

  • Sung, Jai-ki;Lee, Hee-chon;Yoon, Jung-hee;Lee, Young-won;An, Yong-joo;Choi, Ho-jung;Choi, Ji-hye
    • Korean Journal of Veterinary Research
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    • v.38 no.4
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    • pp.918-928
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    • 1998
  • The present study was done with two aims. First, to evaluate the radiographic measurements of liver volumes in normal and hepatomegaly dogs induced by carbon tetrachloride. Second, to investigate quantitative tissue echo pattern by ultrasonography. Gray level histogram of the normal liver and the kidney were estimated with carbon tetra-chloride intoxication. In normal, r-square for liver volume to body weight was 0.93372, and this showed direct linear regression. Gray level histograms of the normal liver and the kidney were $19.150{\pm}2.490$(mean${\pm}$SD) and $13.175{\pm}2.686$(mean${\pm}$SD) respectively(p < 0.01). Liver parenchymal echogenicity was more hyperechogenic than kidney cortex echogenicity. Liver/Kidney ratio was $1.504{\pm}0.313$ and it can be used relative comparison of liver and kidney parenchymal echogenicity. In carbon-tetrachloride($CCl_4$) intoxication, changes of liver volume appeared to increase up to 24 hours after administration (p < 0.05), and decreased gradually to normal level after 2~5 days. Gray level histogram of liver parenchyma decreased up to 24hours (p < 0.01) after intoxication and then gradually increased to normal level. But that of kidney cortex had no significant change. Liver/Kidney ratio also decreased by 2 days(p < 0.01) and then gradually increased to normal level. On histopathologic features of hepatic tissues in carbon tetrachloride intoxication, both coagulative necrosis of hepatic cell and hemorrhage of centrilobular & midzonal area were identified. Conclusively, plain radiography is a useful diagnostic method for evaluating liver volume in mild hepatomegaly. Especially, it is considered that an adequate numerical processing of the liver length, depth and thoracic width and depth measurement would be helpful. Using gray level histogram, ultrasonographic evaluation was useful objective methods in early diagnosis of diffuse hepatic disease.

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Antioxidant Activity of Different Lipid Extracts from Squid Viscera (오징어 내장으로부터 추출한 지질성분의 항산화효과)

  • JEONG Yong-Sil;HONG Jeong-Hwa;BYUN Dae-Seok
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.27 no.6
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    • pp.696-703
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    • 1994
  • To utilize waste of squid effectively, antioxidant properities of squid viscera were elucidated. Major fatty acids of total lipid, neutral lipid and phospholipid were $C_{16:0},\;C_{18:1}\;and\;C_{20:5},\;C_{22:6}$ and consisted $63{\sim}71\%$ of total fatty acids. Total lipid did not show significant antioxidant activity when added to the fish oil at the concentration below $5.0\%$, Antioxidant activity of hexane extract was lower than total lipid or tetra carbon chloride-methanol($CCl_4-MeOH$) extract. Extracts with $CCl_4-MeOH$ exerted higher antioxidant activity as the methanol ratio was increased, suggesting that polar lipid plays and important role.

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Study for Reducement of Polymerization Time and Improvement of Stability in Manufacturing Carboxylated Styrene-butadiene Latex (카르복실화 스티렌-부타디엔 라텍스의 중합시간 단축과 안정성 개선을 위한 연구)

  • Cho, Ur-Ryong
    • Elastomers and Composites
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    • v.37 no.1
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    • pp.31-38
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    • 2002
  • Polymerization of carboxylated styrene-butadiene latex takes longer time than that of acrylic emulsion due to delocalization of radical in butadiene unit having conjugated double bond. A latex stability is the most important properties owing to use intact without separating polymer from base latex. For reducing polymerization time without decreasing any properties of latex, carbon tetra-chloride which has been used as the most popular chain transfer agent was replaced to combination of tert-dodecylmercaptane and ${\alpha}$-methylstyrene dimer. The replacement yielded reducement or 2 hr in polymerization time. In the increment step, charge amount of acrylic acid was limited to 0.3 part to restrain viscosity enhancement. Just after initial step, addition of 0.1 part acrylamide prevent polymer chain from diffusing between two region followed by giving hardness and final good adhesive force to latex particles.