• Computers and Concrete
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• v.13 no.4
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• pp.423-436
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• 2014

Ground Granulated Blast Furnace Slag (GGBFS) is widely used as an effective partial cement replacement material. GGBFS inclusion has already been proven to improve several performance characteristics of concrete. GGBFS provides enhanced durability, including high resistance to chloride penetration and protection against alkali silica reaction. In this paper results of an experimental research work on influence of low-reactivity GGBFS (which is largely available in Iran) on the properties of mortars and concretes are reported. In the first stage, influence of GGBFS replacement level and fineness on the compressive strength of mortars was investigated using Taguchi method. The analysis of mean (ANOM) statistical approach was also adopted to develop the optimal conditions. Next, based on the obtained results, concrete mixtures were designed and water penetration, capillary absorption, surface resistivity, and compressive strength tests were carried out on highstrength concrete specimens at different ages up to 90 days. The results indicated that 7-day compressive strength is adversely affected by GGBFS inclusion, while the negative effect is less evident at later ages. Also, it was inferred that use of low-reactivity GGBFS (at moderate levels such as 20% and 30%) can enhance the impermeability of high-strength concrete since 28 days age.

• Korean Chemical Engineering Research
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• v.58 no.2
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• pp.286-292
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• 2020

This study presents an angular-based measurement on three-dimensional paper-based analytical devices (3D-PADs) for quantitative detection of albumin without using an image analyzer. We demonstrate a simple quantitative and straightforward approach based on the angle of the discolored area as detection criteria. 3D-PADs are rapidly fabricated by the wax-printing and laminating process. The 3D-PADs are treated with citrate buffer and tetrabromophenol blue to react with albumin in a sample solution. Dropping sample solution into sample pad in the 3D-PAD, fluid flows toward the assay zone laterally and vertically by capillary action. We find that the change of angle of the discolored area correctly reflects the concentration of albumin and is reliable determinant for the measurement of the albumin concentration. It is the first demonstration of angular-based detection as a simple, inexpensive, and equipment-free approach for point-of-care diagnosis.

• The Journal of the Korean bone and joint tumor society
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• v.8 no.3
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• pp.76-82
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• 2002

Purpose: Benign bone tumor of the talar body have rarely been evaluated according to the therapeutic methods because of the scarcity of their incidence. Here, we report our experience of 8 cases who were treated by using of posterior approach and curettage through the posterior process of the talus. Materials and Methods: Between February 1986 and October 2001, we experienced 8 cases of benign bone tumor occurring in the talar body. They included two osteoid osteomas, two giant cell tumors, one capillary hemangioma, one chondroblastoma, one simple bone cyst, and one osteochondroma. Their mean age was 22.1 years (ranging from 10 to 41 years). Mean follow-up period was 7.7 years (ranging from 1 to 16 years). All patients were treated by using of posterior approach. Two osteoid osteomas and one osteochondroma were treated by excision of tumors. Other cases were treated with curettage through the cortical window on the posterior process of the talus. Results: There was no recurrence during the follow-up period. one infection occurred. Except this case, all patients had no pain in weight-bearing, and complete range of movement at the ankle joint was reserved in each case. Conclusion: In this study, we suppose that posterior approach to the talar body may be a safe method with minimal damage of normal tissues and sufficient of curettage is capable through the cortical window on the posterior process of the talus.

• Journal of the Korea institute for structural maintenance and inspection
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• v.17 no.6
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• pp.122-129
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• 2013

Since electrical resistivity of concrete can be measured in a more rapid and simple way than chloride diffusivity, it should be primarily regular quality control of the electrical resistivity of concrete which provides the basis for indirect of quality control of chloride diffusivity during concrete construction. If this is realized, the electrical resistivity of concrete can be a crucial parameter to establish maintenance strategy for marine concrete structures. The purpose of this study is to develop, design and test a surface electrical resistivity measurement protocol. Microstructural affecting factors such as capillary water, porosity, tourtousity, and so on, on the electrical resistivity of concrete were examined taking into account for mixing proportion properties, and hydration stage. This study can provide a non-destructive approach for durability design of marine concrete. From the relationship between electrical resistivity and chloride diffusivity, it is expected that the result is subsequently used as a calibration curve for an indirect control of the chloride diffusivity based on regular measurements of the electrical resistivity during concrete construction.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.85-89
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• 2021

Background : Klippel-Trenaunay-Weber syndrome (KTS) is a rare congenital medical condition characterized by complex vascular malformation. KTS consists of a classic triad of capillary malformation (hemangioma), venous malformations and bone or soft tissue hypertrophy causing limb asymmetry. The aim of this report is to describe management for gait disturbance and foot pain in a Patient with KTS using custom-made total contact insole. Case presentation : A 32-year-old man with KTS presented with a 3-year history of gait disturbance on hard surface due to right first toe pain and Achilles tendon tightness. The patient had soft tissue hypertrophy, varicose veins and port-wine stains over the right lower limb associated with KTS. True leg length discrepancy was 2 cm. We prescribed custom-made total contact insole to protect his deformed foot and correct leg length discrepancy. The insole of right side included wedge shaped heel lift and the insole of left side included full length lift to add extra support on unaffected side. Also, we provided compression stocking and physiotherapy including manual lymphatic drainage for lymphedema and stretching exercise for tightness in right lower extremity. At 3 years follow-up, postural alignment including pelvic obliquity was improved using a custom-made total contact insole. The degree of scoliosis and foot pain were also reduced. Conclusion : An individualized and multidisciplinary approach is essential regarding the complexity of comorbidities in patients with KTS. For patients with KTS, orthotic management should be considered to prevent and correct deformities related to KTS. Active orthotic management, compression stocking and physiotherapy can enhance the quality of life and function in patients.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.2
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• pp.228-233
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• 2022

Arteriovenous malformations (AVMs) are rare congenital anomalies characterized by direct communication between arteries and veins that bypass the capillary bed. AVMs may not manifest clinically until late infancy or childhood. In particular, facial AVMs can cause urgent life-threatening dental events. A 5-year-old girl without a medical history visited the hospital because of spontaneous gingival bleeding around the posterior gingival area of the lower left 2nd primary molar. Angiography through the femoral approach under general anesthesia was performed for differential diagnosis and therapeutic option. The blood flow was effectively reduced after arterial embolization alone, and there was no evidence of recurrence at the 5-month follow-up. The present study reports that embolization of the affected vessels can be a more effective and safe method than surgical resection for the treatment of AVM during the growth period.

• Journal of the Korean Geotechnical Society
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• v.29 no.1
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• pp.93-107
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• 2013

Thermal conduction of the particulate composites or granular materials can be widely used in porous materials and geotechnical engineering. And it has continued to develop "effective thermal conductivity" of medium by modeling energy relationship among particles in medium. This study focuses on the development of the effective thermal conductivity at the unsaturated conditions of soils using the modified network model approach assisted by synthetic 3D random packed systems (DEM method, Discrete Element Method) at the particle scale. To verify the network model, three kinds of glass beads and the Jumunjin sand are used to obtain experimental values at various unsaturated conditions. The PPE (Pressure Plate Extractor) test is then performed to obtain SWCC (Soil-Water Characteristic Curve) of soil samples. In the modified network model, SWCC is used to adjust the equivalent radius of thermal cylinder at contact area between particles. And cutoff range parameter to define the effective zone is also adjusted according to the SWCC at given conditions. From a series of laboratory tests and the proposed network model, the modified network model which adopts a SWCC shows a good agreement in modeling thermal conductivity of granular soils at given conditions. And an empirical correlation between the fraction of the mean radius (${\chi}$) and thermal conductivity at given saturated condition is provided, which can be used to expect thermal conductivity of the granular soils, to estimate thermal conductivity of granular soils.

• Analytical Science and Technology
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• v.30 no.6
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• pp.348-354
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• 2017

In this study, patterns of proteome expression were monitored and specifically expressed proteins in human milk were detected in collected human milk after 1 week, 3 weeks, and 6 weeks from delivery. A quantitative shotgun proteomic approach was used to identify human milk proteins and reveal their relative expression amounts. For each sample, two independent human milk samples from two mothers were pooled, and then three replicated shotgun proteomic analyses were carried out. Casein, which is a highly abundant protein in human milk, was removed, and then trypsin was treated to produce a digested peptide mixture. The peptides were loaded in the home-made reversed-phase C18 fused-silica capillary column, and then the eluted peptides were analyzed by using a linear ion-trap mass spectrometer. The relative quantitation of proteins was performed by the normalized spectral count method. For each sample, 81-109 non-redundant proteins were identified. The identified proteins consisted of glycoproteins, metabolic enzyme, and chaperon enzymes such as lactoferrin, carboxylic ester hydrolase, and clusterin. The comparative analysis for the 63 proteins, which were reproducibly identified in all three replications, revealed that 25 proteins were statically significant differentially expressed. Among the differentially expressed proteins, Ig lambda-7 chain C region and tenascin drastically decreased with the delivery time.

• Applied Chemistry for Engineering
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• v.18 no.6
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• pp.643-649
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• 2007

Lipase-catalyzed esterification of structural butanol isomers and n-butyric acid was investigated in supercritical carbon dioxide. The experiments were performed in a high pressure cell for 5 hrs with a stirring rate of 150 rpm at 323.15 K and 130 bar. The Candida Antarctica lipase B (CALB) was used in whole system as a catalyst. The experimental results were analyzed by GC-FID using a INNOWax capillary column. The conversion yield and the tendency of the esterification in supercritical carbon dioxide were compared with estimated results by molecular dynamics simulation. Based on the Ping-Pong Bi-Bi mechanism with competitive inhibition, each step of the reaction was optimized; using this result the transition state was predicted. Conformational preference of isomers was also analyzed using molecular dynamics simulations. This kind of approach will be further extended to the prediction of enzyme-catalyzed reactions using computers.

• Journal of Korean Ophthalmic Optics Society
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• v.14 no.3
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• pp.17-27
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• 2009

Purpose: This review article was written to determine the effects of parameters characterizing a hard contact lens (RGP included), such as BCs, diameters, edge angles, on the time interval for tight fitted lens to return to the equilibrium when it was decentered from blinking. Methods: A mathematical formulation was established to relate or calculate the restoring forces and thickness of lacrimal layer beneath the cornea with the various lens parameters when the tight fitted lens was decentered from blinking. Based on this formulation the differential equations and their numerical solution program were set up to describe the time dependence of the lens on the position and to estimate the time for the lens's return to the equilibrium after blink. Results: It is found that the time interval for the tight fitted lens to return to the equilibrium decreases as either the BC decreases or the diameter increases because both the reduction in BC and increase in diameter result in the increase in the lacrimal layer thickness between the lens and cornea increase which yielded the lowering of the viscous friction in the lens motion. As the edge angle of tight fitted lens increases the time for recentering decreases due to the increase in restoring force without change in lacrimal thickness beneath the lens. In the case of flat fitted hard lens (RGP included), the lacrimal layer thickness under the lens increases as either BC or diameter increases which results in reduction in viscous friction so that the time for the lens's return to the equilibrium were to decrease. The edge angle of flat fitted lens does not affect the lens motion. Conclusions: The effect of BCs on the lens motion (time to approach the equilibrium) was concluded to be significant with both tight and flat fitted lens where its results are contrary with each other. The edge angle of lens only affects the motion in tight fitted lenses.