• Korean Journal of Environmental Biology
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• v.33 no.1
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• pp.1-6
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• 2015

Increased harmful algal blooms by cyanobacteria are threatening public health and limiting human activities related with freshwater ecosystems. Phosphorus (P) has long been suggested as a critical nutrient for cyanobacterial bloom through field research in Canada during the 1970s, proposing a P-based freshwater management guideline. However, recently, nitrogen (N) has also been highlighted as an impacting nutrient on cyanobacterial harmful algal blooms (CyanoHABs). Due to the intensive and frequent observation of Microcystis, this kind of paradigm shift from P limitation to season-dependent N or P limitation has an important implication for a dual nutrient management strategy in eutrophic freshwaters. Through recent international researches, general strategies to control CyanoHABs in lakes and reservoirs are as follows: a dual nutrient (N & P) reduction, wastewater collection and treatment, pre-treatment of influent water in buffer zones, dredging of sediment, reduction of residence time, algal collection, and precipitation and flocculation of cyanobacteria. In addition, sustainable and integrative freshwater algae management should be carried out, based on the ecological aspect, because cyanobacteria are not the target organism to be eradicated, but an essential microbial member in the freshwater ecosystem.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.06a
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• pp.208-208
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• 2009

최근 광섬유 센서기술의 수요는 전 산업분야에 걸쳐 높아지고 있으며, 이에 비례하여 기업 간, 국가 간 경쟁이 첨예화되고 있다. 또한 소형화, 경량화, 고성능화 센서에 대한 요구도 높아지고 있어 종래의 각종 센서들의 형태와 개선을 위한 연구개발이 매우 활발하게 전개되고 있으므로 이를 대체할 수 있는 광섬유 센서의 수요가 급격히 늘어날 전망이다. 기존 침입자 감지 시스템은 태풍, 낙뢰, 폭설, 폭우 등의 기상변화나 지반 흔들림, 통행차량 진동 및 전자기 간섭 등에 영향을 받아 오작동, 오경보가 빈번히 발생된다. 이러한 문제의 해결책으로 광섬유 센서 케이블을 이용한 시스템이 대안으로 부각되고 있다. 현재 국내에서 군부대, 공항을 중심으로 펜스와 휴전선 철책에 힘입자 감지를 위하여 도입되고 있다. 광섬유 센서 케이블을 사용하는 광망경비시스템은 광섬유 센서 케이블을 그물망 형태(광망)로 만들어 경계 지역에 설치된다. 광망경비시스템의 원리는 광섬유에 광펄스를 입사시켜 순환시키는데 침입자가 광망을 절단하거나 외력을 가할 경우 발생되는 레일리 산란에 기인하는 후방산란과 접속점과 파단점에서 생기는 반사광을 OTDR(Optical Time Domain Reflectometer)로 검출하여 침입상황 및 침입위치를 탐지한다. 그러나 이러한 침입자 감지를 위한 광망경비시스템의 핵심부품인 광섬유 센서 케이블은 기존에 전량 해외수입에 의존하고 있는 실정이며, 지금까지 국내에서 생산하기 위한 제작 기술과 노하우가 초보단계에 머물러 있다. 이러한 광섬유 센서 케이블 제작에 있어서 중요한 부분이 패키징 기술이라 할 수 있다. 이는 광섬유 센서를 일반적인 피복 구조로 패키징하게 되면, 센서 고유의 특성이 패키징 과정과 운반과정, 포설과정에서 변하게 되고 센서로써의 신뢰성이 크게 저하된다. 본 연구에서는 힘입자 감지용 광섬유 센서 케이블의 설계와 제작을 위한 제조공법을 확립하고, 이를 이용해 제작된 광섬유 센서 케이블의 신뢰성 특성을 평가하였다. 설계 제작된 광섬유 센서 케이블의 구조는 멀티모드광섬유(MMF) 에 0.9 mm Tight buffer를 코팅하고, 광심선 주위에 아라미드 얀을 삽입시킨 후 고문자 수지를 적용하여 외부 피복 (jacket)을 하였다. 제작된 광섬유 센서 케이블의 외경 측정결과 기준치 ($2.95\;{\pm}\;0.03$ mm)를 모두 만족하였고, 850 nm 파장에서의 광 손실 측정 결과 4.0 dB/km 이하였다. 또한 주요 항목의 신뢰성 특성 시험결과, 인장강도는 8~10 kg의 인장력을 갖으며 온도순환시험 ($-30^{\circ}C\;{\sim}\;+75^{\circ}C$)에서의 광 손실은 0.6 dB 이하로 나타나 침입자 감지용 광섬유 센서 케이블로 적합함을 확인할 수 있었다.

• The Korean Journal of Mycology
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• v.27 no.2 s.89
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• pp.112-118
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• 1999

Strains of Fusarium oxysporum f. sp. lycopersici isolated from Korea, Japan and U.S.A. were used for electrophoretic karyotype (EK) analysis. Chromosome separations on FastLane agarose gels (FMC BioProducts, Rockland, ME), called pulsed field gel electrophoresis (PFGE), were performed by CHEF-DRII apparatus (Bio-Rad Laboratories, Melville, NY) using TAE as a running buffer. To obtain optimal condition for separation of chromosome sized DNAs, variable running conditions such as field strengths, swithching intervals, and running time were applied in CHEF gel electrophoresis. We were able to resolve 9 to 11 chromosome sized DNAs ranging in size from 0.76 to 6.41 Mb in isolates from Korea and estimate that the total genome size was ranging from 35.29 to 38.92 Mb. Distinct differences in length range and genome size exist among isolates from different countries. Isolates from Japan and U.S.A. were resolved 9 to 11 chromosome sized DNAs ranging in size from 1.24 to 6.85 Mb and estimated that the total genome size was ranging from 35.32 to 43.87 Mb. Isolates from variable provinces in Korea had the same or similar chromosomal polymorphism and showed different chromosomal DNA patterns compared to isolates from the other countries.

• Journal of Korea Multimedia Society
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• v.8 no.4
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• pp.439-449
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• 2005

Distributed main memory database management systems (DMM-DBMSs) store the database in main memories of the participating sites. They provide high performance through fast access to the local databases and high speed communication among the sites. Recently, a lot of research results on DMM- DBMSs has been reported. However, to the best of our knowledge, there is no known research result on the performance of the catalog management schemes for DMM-DBMSs. In this work, we evaluated the performance of the partitioned catalog management schemes through experimental analysis. First, we classified the partitioned catalog management schemes into three categories : Partitioned Catalogs Without Caching (PCWC), Partitioned Catalogs With Incremental Caching (PCWIC), and Partitioned Catalogs With Full Caching (PCWFC). Experiments were conducted by varying the number of sites, the number of terminals per site, buffer size, write query ratio, and local query ratio. Experiments show that PCWFC outperforms the other two schemes in all cases. It also means that the performance of PCWIC gradually increases as time goes by. It should be noted that PCWFC does not guarantee high performance for disk-based distributed DBMSs in cases when the workload of individual site is high, catalog write ratio is high, or remote data objects are accessed very frequently. Main reason that PCWFC outperforms for DMM-DBMSs is that query compilation and remote catalog access can be done in a very high speed, even when the catalogs of the remote data objects are frequently updated.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• autumn
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• pp.353-358
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• 2003

Recently there has been huge efforts to improve performance in construction process by applying emerging techniques such as the Lean principle, Just-in-time concept and so on. However, little achievement as we expected has come out in reality due to the lack of strategy to set a definite goal of the execution and differences of personal viewpoints on construction productivity. Accordingly, it is the most important to promote the circumstances for the construction process improvement by quantifying the goals of respective unit activity groups. This research explores feasible solutions for the improvement of construction projects performance by combining the six-sigma principle for the generic administrative innovation based on the idea of construction process performance. For this purpose, mutual comparisons of various current approaches are performed in an attempt to establish the advantages in applying six-sigma idea and to provide its fundamental strategy. Furthermore, through a case study with the simulation of applying six-sigma to a unit activity group in construction process, this paper verifies that the overall performance improves as the degree of sigma level gets advanced.

• Journal of Pharmaceutical Investigation
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• v.33 no.3
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• pp.237-243
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• 2003

Erdosteine, the thiol derivatives chemically related to cysteine, is a mucolytic and mucoregulator agent which modulates mucus production and viscosity and increases mucociliary transport. The purpose of the present study was to evaluate the bioequivalence of two erdosteine capsules, Erdos (Dae Woong Pharmaceutical Co., Korea) and Erblon (Kuhn Il Pharmaceutical Co., Korea), according to the guidelines of Korea Food and Drug Administration (KFDA). The erdosteine release from the two erdosteine capsules in vitro was tested using KP VII Apparatus II method with various different kinds of dissolution media (pH 1.2, 4.0, 6.8 buffer solution and water). Twenty four healthy male subjects, $23.33{\pm}2.06$ years in age and $66.18{\pm}8.19\;kg$ in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After three capsules containing 300 mg as erdosteine were orally administered, blood was taken at predetermined time intervals and the concentations of erdosteine in serum were determined using HPLC method with UV detector. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as $AUC_t,\;C_{max}\;and\;T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t\;and\;C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the Erdos were 0.20%, 1.10% and -9.44% for $AUC_t,\;C_{max}\;and\;T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25) $(e.g.,\;log(0.94){\sim}log(1.22)\;and\;log(0.92){\sim}log(1.20)\;for\;AUC_t\;and\;C_{max},\;respectively$. Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating Erblon capsule and Erdos capsule are bioequivalent.

• The Transactions of the Korea Information Processing Society
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• v.4 no.1
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• pp.237-245
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• 1997

In this paper, a flow control mechanism is proposed which is based on the priority control between communication path of a node. In this scheme, demanding length of a data queue for any pre-defined, then each node in that path is forced to maintains buffer size under the limit by controlling priority level of the path. The communication path which requires higher bandwidth sets its demanding queue length smaller. By providing relationship between the priority of a path and length of its queue, the high bandwidth requesting path has a better chance to get high bandwidth by defining the smaller demanding queue size. And also, by forcing a path which has high flow rate to maintain small queue size in the path of the communication, the scheme keep the transmission delay of the path small. The size of the demanding queue of a path is regularly adjusted to meet the applications requirement, and the load status of the network during the life time of the communication. The priority control based on the demanding queue size is also provided in the intermediate nodes as well as the end nodes. By that the flow control can provide a quicker result than end to-end flow control, it provides better performance advantage especially for the high speed network.

• Journal of Nutrition and Health
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• v.19 no.6
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• pp.363-373
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• 1986

This study was devised to elucidate whether soused shrimp exhibits a digestive action on boiled pork meats. and the mechanism by which sousing with a high concentration of sodium chloride preserves nutrients in foods for a prolonged pe\ulcornerriod. Protease was isolated from soused shrimp using a combination of ammonium sulfate fractionation. DEAE - cellulose ion exchange chromatography and gel filtra\ulcornertion. The isolated protease had specific activity of 1.560 units. 210 purification fo\ulcornerld with an yield of 38%. Its optimum pH and temperature were 8.0 and $43^{\circ}C$ respectively. The molecular weight of the enzyme was 35.000. The Km value of the enzyme for casein was 1.6 x $10^{-6}$ M The e=yme required the presence of cu\ulcornerpric ion to exhibit its full activity. Eighty eight percent of the enzyme activity was in\ulcornerhibited by 3.5M NaCI showing a reversibly linear decrease of the enzyme activity as NaCI concentration increased. The nature of the inhibition by NaCl was rever\ulcornersible and noncompetitive. The protease activity in soused shrimp was well preser\ulcornerved with the elapse of time at least in part due to NaCI induced suppression of autodigestion. The enzyme was denatured by acid easily. i.e. 1% of the original activity remained after staying at pH 2 for 10 minutes. which is within the norm\ulcorneral range of pH of the human stomach. Soused shrimp was observed to be one of those containing the highest protease activity compared with the other soused foo\ulcornerds such as soused oyster. squid. clam. and Pollack intestine with respect to spec\ulcornerific activities of dialized 1:4 whole homogenates(w/v) in 5 mM sodium phospha\ulcornerte - 2.4 mM j3 - mercaptoethanol buffer. pH 8.0. Casein and boiled meats including pork, beef, and chicken appeared to be the good substrates for the protease. Casein was the best. Therefore. the ingestion of boiled meats including pork together with soused sh\ulcornerrimp would help digestion of boiled pork in human not only by increasing appe\ulcornertite also by the direct proteolytic digestion of boiled meats by soused shrimp to\ulcorner some extent. And a high concentration of sodium chloride inhibited the protease activity reversibly in a remarkable degree, which ensued in a significant retardat\ulcornerion of autodigestion of protein in foods by proteases, and hereby contributed to the preservation of foods for an extended period.

• Biomedical Science Letters
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• v.6 no.3
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• pp.223-228
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• 2000

The purpose of this study was to find out the effect of He-Ne, IR laser therapy for 4 and 10 minutes on healing of septic arthritis. Sprague-Bawley rats (212.1$\pm$10 g) were randomly assigned to one control and three arthritis groups. Septic arthritis groups were divided into arthritis control, 4 or 10 minute laser therapy groups. Arthritis was experimentally induced by intraperitoneally administration of staphylococcus aureus in citrate buffer(pH 4.3). These result were obtained as follows: AST, LDH, ALP, CK activities and IgG concentration in 10 minute laser group were signifantly increased compare with those in the arthritis group. AST, LDH and CK activities in 4 minute laser group were significantly decreased compare with those in the arthritis group. We think that laser therapy in 4 minute may effective on the healing of septic arthritis. And we will have to study of the effect of laser therapy on healing mechanism, appropriate time of septic arthritis.

• Journal of Soil and Groundwater Environment
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• v.10 no.1
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• pp.1-5
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• 2005

Nitrate reduction with zero valent iron $(Fe^0)$ has been extensively studied, but the proper treatment for ammonium byproduct has not been reported yet. In groundwater, however, ammonium is regarded as contaminant species, and particularly, its acceptable level is regulated to 0.5 mg-N/L. for drinking water. This study is focused on developing new material to reduce nitrate and properly remove ammonium by-products. A new material, Fe-loaded zeolite, is derived from zeolite modified by Fe(II) chloride followed by reduction with sodium borohydride. Batch experiments were performed without buffer at two different pH to evaluate the removal efficiency of Fe-loaded zeolite. After 80 hr reaction time, Fe loaded zeolite showed about $60\%$ nitrate removal at initial pH of 3.3 and $40\%$ at pH of 6 with no ammonium release. Although iron filing showed higher removal efficiency than Fe-loaded zeolite at each pH, it released a considerable amount of ammonium stoichiometrically equivalent to that of reduced nitrate. In terms of nitrogen species including $NO_3-N$ and $NH_4^+-N$, Fe-loaded zeolite removed about $60\%\;and\;40\%$ of nitrogen in residual solution at initial pH of 3.3 and 6, respectively, while the removal efficiency of iron filing was negligible.