• International Journal of Oral Biology
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• 제44권4호
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• pp.152-159
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• 2019

The oral care probiotic strain Weissella cibaria CMU (oraCMU) inhibits volatile sulphur compounds associated with halitosis, presumably by inhibiting the growth of associated oral pathogens. In the present study, we investigated whether oraCMU inhibits the production of these compounds by suppressing the expression of mgl. This gene encodes L-methionine-α-deamino-γ-mercaptomethane-lyase (METase) and is involved in the production of methyl mercaptan (CH₃SH) by Porphyromonas gingivalis. Therefore, we specifically investigated the effects of oraCMU on the growth, CH₃SH production, METase activity, and mgl expression of P. gingivalis. The minimum inhibitory concentrations of cell-free supernatant and secreted proteins from oraCMU were 125 mg/mL and 800 ㎍/mL, respectively. At sub-minimum inhibitory concentration levels, these metabolites inhibited CH₃SH production, but they also reduced P. gingivalis viability. Only heat-killed oraCMU decreased CH₃SH production without affecting P. gingivalis viability. Heat-killed oraCMU also inhibited METase activity toward L-methionine and mgl mRNA expression (p < 0.05). In summary, we demonstrated the inhibition of volatile sulphur compounds via the antimicrobial action of oraCMU and, for the first time, the inhibition of such compounds by heat-killed oraCMU, which occurred at the molecular level.

• 한국멀티미디어학회논문지
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• 제21권9호
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• pp.1076-1089
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• 2018

Respiration is the process of moving air into and out of the lung. Respiration changes the temperature in the chamber while exchanging energy. Especially the temperature of the face. Respiration monitoring using an infrared camera measures the temperature change caused by breathing. The conventional method assumes that motion is not considered and measures respiration. These assumptions can not accurately measure the respiration rate when breathing moves. In addition, the respiration rate measurement is performed by counting the number of peaks of the breathing waveform by displaying the position of the peak in a specific window, and there is a disadvantage that the breathing rate can not be measured accurately. In this paper, we use KLT tracking and block matching to calibrate limited weak movements during breathing and extract respiration waveform. In order to increase the accuracy of the respiration rate, the position of the peak used in the breath calculation is calculated by converting from a single point to a high resolution. Through this process, the respiration signal could be extracted even in weak motion, and the respiration rate could be measured robustly even in various time windows.

• Journal of Nutrition and Health
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• 제32권8호
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• pp.908-917
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• 1999

This study was done to compare nutrient intakes, anthropometric indices, and psychosocial factors related to smoking by smoking status among adolescent girls in Seoul. Subjects were high school students, and smokers were 17.6%. Nutrient intakes were analyzed by convenient method, and anthropometric measurements were done by Inbody 2.0. Psychosocial factors of smoking were examined based on the Theory of Planned Behavior : 26 attitudinal, 9 normative, and 17 control beliefs were used. Smokers smoked 5-7 cigarettes a day on average, with 1.26 pack-years of smoking, There were no significant differences in anthropometric characteristics, except fat distribution, between smoking(n=92) and nonsmoking(n=92) and nonsmoking(n=94) group. The percentage of alcohol groups. Especially, caloric intake (63.6% of RDA) were much below the recommended level. With respect to psychosocial factors, 18 out of 26 attitudinal beliefs were significantly different between smokers and nonsmokers. Smokers responded less negatively on the items of bad health effects of relax(p<0.001). In addition, smokers were more convinced of advantages of smoking (test, etc.)but responded less negatively on the disadvantages of smoking(bothering others, yellow teeth, bad breath, etc.). Smokers expressed less pressure for not smoking from siblings, friends, school seniors than nonsmokers. In addition, smokers, expressed less confidence in controlling the urge to smoker or quitting smoking in several situations, such as 'after a meal', 'feel bored', 'with friends', 'when angry' offered a cigarette by friends', 'drinking coffee or tea', 'drinking alcohol', 'seeing others smoke'(p<0.001). Smokers also felt less developing in applying specific skills for controlling the urge to smoker or quitting smoking. These findings suggest the need for developing smoking cessation programs for adolescent females, focusing on specific beliefs identified in this study.

• 대한통합의학회지
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• 제9권1호
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• pp.183-192
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• 2021

Purpose : The purpose of this study was to investigate the impact of postural correction training on pulmonary function on 28 college students suspected of turtle neck syndrome, and the following conclusions were obtained. Methods : Turtle neck syndrome suspicion 28 person were randomly divided into a posture training group (n = 14) and group that does not perform posture training (n = 14). Respiratory function was measured by SPIROVIT SP-1 and respiratory gas analyzer. The posture training group performed balloon blowing and stair climbing after 20 minutes of posture training, and the group without posture training carried out balloon blowing training and stair climbing. Five times a week and for two weeks. Results : 1. The comparison of the FVC before and after experiments caused by balloon blowing showed a higher level of effortful pulmonary function in the control group than in the experimental group. 2. Comparison of PEFs before and after the experiment by balloon blowing showed that the experimental group's peak flow rate was higher than that of the control group. 3. Comparison of the FIVC before and after experiments with balloon blowing showed that the comparison of the FIVC showed a higher level of effortless intake pulmonary function in the control group than in the experimental group. 4. The comparison of the maximum ventilation volume(VE) before and after the experimental gas measurement showed that the maximum ventilation rate of the experimental group was higher than that of the control group. 5. The comparison of pre-test and post-test heart rate(HR) by breath gas measurement showed that the heart rate of the control group was higher than that of the experimental group. Conclusion : the results of this study showed that postural correction training, balloon blowing training, and stair climbing could have a positive impact on improving pulmonary function. However, the two-week experiment conducted five times a week showed an increase in pulmonary function, but it was difficult to see the effect due to the short study period. Therefore, it is hoped that later studies will be conducted more systematically on the effects of breathing exercises on improving pulmonary function after post-postural correction training for patients with pulmonary function problems.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2008년도 춘계종합학술대회 A
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• pp.894-897
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• 2008

스트레스는 현대 인간 문명사회에서의 피할 수 없는 결과이며 복잡한 현상이다. 또한 이의 통제 유무에 따라 인간의 활동능력은 심각한 변화를 받을 수 있다. 스트레스는 자극 호르몬인 아드레날린이나 다른 스트레스 호르몬이 혈중 내로 분비되어 우리 몸을 보호하려고 하는 반응으로 위험으로부터 싸우거나 멀리 피해버리는 힘과 에너지를 제공한다. 이러한 변화는 근유, 뇌, 심장에 더 많은 피를 보낼 수 있도록 맥박과 혈압을 증가시키고 더 많은 산소를 얻기 위해 호흡이 빨라지는 현상이 나타난다. 이에 본 논문에서는 스트레스를 통해 증가된 맥박과 혈압, 호흡수를 측정한 후 스트레스를 완화시키기 위한 방편으로 음악을 이용한 감성 기반 매칭 시스템을 설계한다. 음악에 따른 HRV와 APG의 변화율을 살펴보고 Zigbee를 이용하여 맥박, 혈압, 호흡수를 측정한 후 감성 음악을 기반으로 하여 스트레스를 완화시킬 수 있는 시스템을 제안한다.

• 해양환경안전학회지
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• 제19권2호
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• pp.219-224
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• 2013

해양유류오염사고가 발생한 경우에 필요한 모든 방제자원을 사전에 확보하고 사고에 대응하는 것이 가장 효과적이지만 현실적으로는 한계가 있는 실정이다. 그러므로 대규모 유류오염사고에 대비하여 유류오염으로 피해를 입게 되는 오염지역의 어선을 활용하는 방안이 중요한 대안이 될 수 있다. 미국 등 선진국에서도 지역 어선을 이용한 임시방제정 프로그램이 개발되어 운영되고 있는 사례를 찾아볼 수 있다. 본 연구는 국내 소형어선에 적합한 기름방제용 스위핑 암 시스템을 검토하였다. 모델로 선정된 소형 선박은 연안유자망어선 및 연안복합어선으로 2.5~3.5톤, 길이 8~9 m, 폭 2.5~2.8 m, 마력 200~250 HP, 선질 FRP인 어선이다. 개발된 장치는 모델 선박에 간편하게 장착할 수 있고 이동이 가능한 구조로 설계되었다. 조립 및 분해를 쉽게 하기위해 각 부품의 무게를 10 kg 이하로 구성함으로써 현장 실용성을 높였다.

• 분석과학
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• 제14권2호
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• pp.180-190
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• 2001

화합물에 포함된 냄새를 유발하는 물질은 다양한 성분으로 되어 있다. 냄새를 유발하는 휘발성 화합물의 분석에는 GC 또는 GC/MSD 등이 많이 사용된다. 그러나, 이들 분석기기는 전체 휘발성 성분의 profile이나 특정성분의 함량을 정량적으로 분석할 수는 있으나, 냄새를 유발하는 지배적인 성분이 무엇인지 파악하기가 어렵다. 이러한 문제점을 해결하기 위해 사용되는 방법에는 GC-Sniffing 또는 GC-Olfactometry법 등이 있다. 본 연구에서는 복합적인 냄새성분을 검출하기 위해 사람의 후각을 이용하는 olfactometry를 기존 GC에 결합시켜 분리컬럼에서 분리된 시료가 동시에 검출되는 GC/FID/Olfactometry를 개발하였다. FID와 ODP 신호간의 시간차이는 물질의 종류와 농도, 그리고 패널에 따라 다르게 나타났다. 일반적으로 휘발성과 냄새강도는 큰 물질일수록, 패널의 호흡주기가 짧을수록 두 신호간의 시간차이가 적었다. 그러므로, 정확한 냄새 원인물질의 규명에는 이들 신호의 관계에 대한 고찰이 필요하다.

• Radiation Oncology Journal
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• 제33권3호
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• pp.250-255
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• 2015

Purpose: To compare audio-only biofeedback to conventional audiovisual biofeedback for regulating patients' respiration during four-dimensional radiotherapy, limiting damage to healthy surrounding tissues caused by organ movement. Materials and Methods: Six healthy volunteers were assisted by audiovisual or audio-only biofeedback systems to regulate their respirations. Volunteers breathed through a mask developed for this study by following computer-generated guiding curves displayed on a screen, combined with instructional sounds. They then performed breathing following instructional sounds only. The guiding signals and the volunteers' respiratory signals were logged at 20 samples per second. Results: The standard deviations between the guiding and respiratory curves for the audiovisual and audio-only biofeedback systems were 21.55% and 23.19%, respectively; the average correlation coefficients were 0.9778 and 0.9756, respectively. The regularities between audiovisual and audio-only biofeedback for six volunteers' respirations were same statistically from the paired t-test. Conclusion: The difference between the audiovisual and audio-only biofeedback methods was not significant. Audio-only biofeedback has many advantages, as patients do not require a mask and can quickly adapt to this method in the clinic.

• Environmental Analysis Health and Toxicology
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• 제17권2호
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• pp.147-160
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• 2002

Volatile organic compounds (VOCs) are an important public health issue in Korea and many important questions remain to be addressed with respect to assessing exposure to these compounds. Because they are ubiquitous and highly volatile, special techniques must be applied in their analytic determination Valid Personal exposure assessment methods are needed to evaluate exposure frequency, duration and intensity, as well as their relationship to personal exposure characteristics. Biological monitoring is also important since it may contribute significantly in risk assessment by allowing the estimation of effective absorbed doses. This study was on ducted to establish the environmental measurement, personal dosimetry and biological monitoring methods for VOCs. These methods are needed to compare blood, urinary and exhalation breath VOC levels and to provide tools for risk assessment of VOC exposure. Passive monitors (badge type) and a active samplers (trap) for the VOCs collection were used for air sampling. Methods development included determining the minimum detectable amounts of VOCs in each media, as well as evaluating collection methods and developing analytical procedures. Method reliability was assessed by determining breakthrough volumes and comparing results between laboratories and with other methods. A total capacity of trap used in this study was 60ι. Although variable by compound, the average breakthrough was 20％. Also, there was no loss of compounds in trap even if keep for 45 day in -7$0^{\circ}C$. The recovery of active and passive methods was 69％ ~ 126％ and method detection limit was 0.24 $\mu\textrm{g}$/trap and 0.07 $\mu\textrm{g}$/badge. There was no statistical difference (P > 0.05) between active and passive methods.

• BMB Reports
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• 제36권1호
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• pp.95-109
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• 2003

Inflammatory lung diseases are characterized by chronic inflammation and oxidant/antioxidant imbalance. The sources of the increased oxidative stress in patients with chronic inflammatory lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) derive from the increased burden of inhaled oxidants, and from the increased amounts of reactive oxygen species (ROS) generated by several inflammatory, immune and various structural cells of the airways. Increased levels of ROS produced in the airways is reflected by increased markers of oxidative stress in the airspaces, sputum, breath, lungs and blood in patients with lung diseases. ROS, either directly or via the formation of lipid peroxidation products such as 4-hydroxy-2-nonenal may play a role in enhancing the inflammation through the activation of stress kinases (JNK, MAPK, p38) and redox sensitive transcription factors such as NF-${\kappa}B$ and AP-1. Recent evidences have indicated that oxidative stress and pro-inflammatory mediators can alter nuclear histone acetylation/deacetylation allowing access for transcription factor DNA binding leading to enhanced pro-inflammatory gene expression in various lung cells. Understanding of the mechanisms of redox signaling, NF-${\kappa}B$/AP-1 regulation, the balance between histone acetylation and deacetylation and the release and expression of pro- and anti-inflammatory mediators may lead to the development of novel therapies based on the pharmacological manipulation of antioxidants in lung inflammation and injury. Antioxidants that have effective wide spectrum activity and good bioavailability, thiols or molecules which have dual antioxidant and anti-inflammatory activity, may be potential therapeutic agents which not only protect against the direct injurious effects of oxidants, but may fundamentally alter the underlying inflammatory processes which play an important role in the pathogenesis of chronic inflammatory lung diseases.