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Correlation between Gait Speed and Velocity of Center of Pressure Progression during Stance Phase in the Older Adults with Cognitive Decline: A Pilot Study

  • Seon, Hee-Chang;Lee, Han-Suk;Ko, Man-Soo;Park, Sun-Wook
    • Journal of the Korean Society of Physical Medicine
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    • v.15 no.4
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    • pp.67-74
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    • 2020
  • PURPOSE: The progression of the center of pressure (COP) velocity of the stance phase may have important roles for predicting gait speed in older adults with cognitive decline. This study was conducted to identify the correlation between gait speed and the velocity of COP progression during the stance phase in older adults with cognitive decline. METHODS: Forty adults aged 65 years or older (twenty participants without cognitive decline, 20 participants with cognitive decline) were recruited. The COP progression velocity was measured using an F-scan pressure-sensitive insole system. The stance phase was divided into four sub-stages. (loading response, mid-stance, terminal stance, and pre-swing). Gait speed, double support phase, and cadence were also measured. Correlations and multiple regression analyses were performed. RESULTS: Gait speed was associated with the COP progression velocity in midstance (r = .719, p < .05), cadence (r = .719, p < .05) and the COP progression velocity in loading response velocity (r = .515, p < .05) in older adults with cognitive decline. However, no correlation was found in older adults without cognitive decline. In multiple regression analysis using gait speed as a dependent variable, the COP progression velocity in midstance and cadence were significant predictors of gait speed, with the COP progression velocity being the most significant predictor. CONCLUSION: The COP progression velocity is an important factor for predicting gait speed in older adults with cognitive decline, suggesting that the cognitive function influences gait speed and the velocity of COP progression.

SIMULATION OF REGIONAL DAILY FLOW AT UNGAGED SITES USING INTEGRATED GIS-SPATIAL INTERPOLATION (GIS-SI) TECHNIQUE

  • Lee, Ju-Young;Krishinamursh, Ganeshi
    • Water Engineering Research
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    • v.6 no.2
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    • pp.39-48
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    • 2005
  • The Brazos River is one of the longest rivers contained entirely in the state of Texas, flowing over 700 miles from northwest Texas to the Gulf of Mexico. Today, the Brazos River Authority and Texas Commission on Environmental Quality interest in drought protection plan, waterpower project, and allowing the appropriation of water system-wide and water right within the Brazos River Basin to meet water needs of customers like farmers and local civilians in the future. Especially, this purpose of this paper primarily intended to provide the data for the engineering guidelines and make easily geological mapping tool. In the Brazos River basin, many stream-flow gage station sites are not working, and they can not provide stream-flow data sets enough for development of the Probable Maximum Flood (PMF) for use in the evaluation of proposed and existing dams and other impounding structures. Integrated GIS-Spatial Interpolation (GIS-SI) tool are composed of two parts; (1) extended GIS technique (new making interface for hydrological regionalization parameters plus classical GIS mapping skills), (2) Spatial Interpolation technique using weighting factors from kriging method. They are obtained from the relationship among location and elevation of geological watershed and existing stream-flow datasets. GIS-SI technique is easily used to compute parameters which get drainage areas, mean daily/monthly/annual precipitation, and weighted values. Also, they are independent variables of multiple linear regressions for simulation at un gaged stream-flow sites. In this study, GIS-SI technique is applied to the Brazos river basin in Texas. By assuming the ungaged flow at the sites of Palo Pinto, Bryan and Needville, the simulated daily/monthly/annual time series are compared with observed time series. The simulated daily/monthly/annual time series are highly correlated with and well fitted to the observed times series.

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Serologic survey of the ruminant bacterial infectious diseases in farmed deer and wild water deer in Jeonbuk province (사육사슴 및 야생고라니에서 소 세균성 전염병에 대한 혈청학적 연구)

  • Jo, Young-Suk;Chung, Yun-Shin;So, Seung-Young;Seol, Min-Suk;Cho, Ho-Seong;Kim, Bum-Seok;Lim, Chae-Woong
    • Korean Journal of Veterinary Service
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    • v.33 no.3
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    • pp.249-254
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    • 2010
  • Deer can be one of the susceptible animals to bovine infectious diseases, and thus, may play a role either as a reservoir or amplifier host for spreading the diseases to other species such as cattle and goat. This study was conducted to determine the serum antibodies to bacterial infectious diseases for brucellosis, tuberculosis (TB), paratuberculosis (Johne's disease) in deer. Serum samples were randomly collected from 78 deer from 31 farms at Jeonbuk province, and 7 wild water deer from Jeonbuk wild animal treatment center during 2005 to 2007, respectively. Four farm deer (5.1%) showed antibodies to tuberculosis using Antigen Rapid Bovine TB Ab Test Kit. One elk (1.3%) and one wild water deer had antibodies for paratuberculosis. Antibody against Brucellosis was not detected in tube agglutination test (TAT) and enzyme-linked immunosorbent assay (ELISA). These data suggest that caution should be applied to inspection of velvet, deer blood and meat for human consumption from deer because of zoonotic bacterial diseases in deer. In addition, farmed deer can be a transmissible host for zoonotic disease to diary or raising farm.

Deep Seawater Increases Dendritic Branches of Cultured Rat Hippocampal Neurons (해양심층수에 의한 해마신경세포 가지돌기 수의 증가)

  • Lee, Hyun-Sook;Nam, Kyung-Soo;Shon, Yun-Hee;Moon, Il-Soo
    • Journal of Life Science
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    • v.18 no.6
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    • pp.897-901
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    • 2008
  • Deep seawater (DSW; deep ocean water) is pure, rich in inorganic materials which have attracted attention for various applications. In this study we investigated the effects of the DSW upwelled from the East Sea, offshore Yang Yang (Korea) on the morphological differentiation of cultured rat hippocampal neurons, which were grown in the minimal essential medium containing 10% (v/v) fetal bovine serum and 25% (v/v) DSW with various hardness. DSW had no effect on initial morphological differentiation (17 hr post-plating). When observed on DIV3, 7, 14, and 17, low hardness (0 and 200) DSW reduced dendritic branching. However, dendritic branches within $80\;{\mu}m$ diameter from the center of soma nearly doubled in neurons grown in hardness 1,000 DSW-containing media. DSW with hardness 600 was more or less same as control groups. These results indicate that DSW with appropriate hardness ameliorates neuronal health.

Evaluating the bond strength of FRP in concrete samples using machine learning methods

  • Gao, Juncheng;Koopialipoor, Mohammadreza;Armaghani, Danial Jahed;Ghabussi, Aria;Baharom, Shahrizan;Morasaei, Armin;Shariati, Ali;Khorami, Majid;Zhou, Jian
    • Smart Structures and Systems
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    • v.26 no.4
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    • pp.403-418
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    • 2020
  • In recent years, the use of Fiber Reinforced Polymers (FRPs) as one of the most common ways to increase the strength of concrete samples, has been introduced. Evaluation of the final strength of these specimens is performed with different experimental methods. In this research, due to the variety of models, the low accuracy and impact of different parameters, the use of new intelligence methods is considered. Therefore, using artificial intelligent-based models, a new solution for evaluating the bond strength of FRP is presented in this paper. 150 experimental samples were collected from previous studies, and then two new hybrid models of Imperialist Competitive Algorithm (ICA)-Artificial Neural Network (ANN) and Artificial Bee Colony (ABC)-ANN were developed. These models were evaluated using different performance indices and then, a comparison was made between the developed models. The results showed that the ICA-ANN model's ability to predict the bond strength of FRP is higher than the ABC-ANN model. Finally, to demonstrate the capabilities of this new model, a comparison was made between the five experimental models and the results were presented for all data. This comparison showed that the new model could offer better performance. It is concluded that the proposed hybrid models can be utilized in the field of this study as a suitable substitute for empirical models.

Study on the Dietetic Internship Program of Catering Company (일부 급식 서비스 기업의 인턴 교육 프로그램에 관한 연구)

  • Jang, Seong-Mi;Lee, Young-Mee
    • Korean Journal of Community Nutrition
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    • v.12 no.3
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    • pp.322-332
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    • 2007
  • The purposes of this research were to examine the effect of the catering company's dietetic internship program through a self-evaluating ability test about management performance between pre and post internship programs and consequently to suggest improvement in the internship program. In this study, two types of questionnaires were conducted in July and October 2006, targeting 41 dietetic interns who trained in a 6 months internship program. Except the 4 dropped interns, data from 37 interns were collected and used for statistical analysis, using the SPSS Win 11.0 version. The results of this study were as follows: First of all, the analysis on the effect of the internship program according to classified management segments showed significant improvements in the following order: purchase management (p<0.001), computer program management (p<0.001), facilities management (p<0.001), accounting management (p<0.01), personnel management (p<0.01), retention management (p<0.01), sanitation management (p<0.01), service management (p<0.01) and foodservice management (p<0.01). However, there was no significantly improvement in management of clients. Secondly, the result of the analysis on the details of each management segment that were significant improvement and changing score was the top 5 duties were as follows: In the purchase management, the score of weekly and daily order management was increased 1.0 (p<0.001), the score of weekly inventory management was 0.81 (p<0.001). In the computation office management, expenses handling through a computer program was 0.65 (p<0.01). In the personnel management, the score of work schedule management increased 0.81 (p<0.001). In the accounting management, the score of monthly profit and loss account management was 0.65 (p<0.001). Furthermore, qualified educational programs connected with the internship program will have to be systematically developed and continually carried out in order to improve service and management abilities of branch managers.

Evaluating the impacts of using piles and geosynthetics in reducing the settlement of fine-grained soils under static load

  • Shariati, Mahdi;Azar, Sadaf Mahmoudi;Arjomand, Mohammad-Ali;Tehrani, Hesam Salmani;Daei, Mojtaba;Safa, Maryam
    • Geomechanics and Engineering
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    • v.20 no.2
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    • pp.87-101
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    • 2020
  • The construction of combined pile-raft foundations is considered as the main option in designing foundations in high-rise buildings, especially in soils close to the ground surface which do not have sufficient bearing capacity to withstand building loads. This paper deals with the geotechnical report of the Northern Fereshteh area of Tabriz, Iran, and compares the characteristics of the single pile foundation with the two foundations of pile group and geogrid. Besides, we investigate the effects of five principal parameters including pile diameter and length, the number of geogrid layers, the depth of groundwater level, and pore water pressure on vertical consolidation settlement and pore water pressure changes over a year. This study assessed the mechanism of the failure of the soil under the foundation using numerical analysis as well. Numerical analysis was performed using the two-dimensional finite element PLAXIS software. The results of fifty-four models indicate that the diameter of the pile tip, either as a pile group or as a single pile, did not have a significant effect on the reduction of the consolidation settlement in the soil in the Northern Fereshteh Street region. The optimum length for the pile in the Northern Fereshteh area is 12 meters, which is economically feasible. In addition, the construction of four-layered ten-meter-long geogrids at intervals of 1 meter beneath the deep foundation had a significant preventive impact on the consolidation settlement in clayey soils.

Potential Industrial Applications and Evolution of Carbohydrolases and Glycansucrases

  • Kim, Do-Man;Seo, Eun-Seong;Lee, Jin-Ha;Kang, Hee-Kyoung;Cho, Jae-Young
    • Proceedings of the Korean Society for Applied Microbiology Conference
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    • 2004.06a
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    • pp.215-218
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    • 2004
  • Dextrans make up a class of polysaccharides that are D-glucans of various structures with contiguous $\alpha$-1longrightarrow6 ~6 glycosidic linkages in the main chains and $\alpha$-1longrightarrow2, $\alpha$-1longrightarrow3, or $\alpha$-1longrightarrow4 branch glycosidic linkages, depending on the specificity of the particular dextransucrase. Glucansucrases that catalyze glucans synthesis from sucrose. When other carbohydrates, in addition to sucrose, are present in the enzyme digest, the enzyme transfers glucose to the carbohydrate acceptors in the secondary reaction that diverts some of the glucose from incorporation into glucan. Many carbohydrate acceptors have been recognized and the products that result are dependent on the particular enzyme and the structure of the particular acceptor. Because of these unique catalytic characteristics, various dextransucrases have many important industrial and medical uses. To improve the understanding of their action mode and extend their applications, this study describes mechanism of glucan synthesis and potential industrial uses of dextransucrases, and our recent findings on the structural, functional organization and directed evolution of the glucansucrases to offer for designing glucansucrases with improved properties.

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Optimization of Gaussian Mixture in CDHMM Training for Improved Speech Recognition

  • Lee, Seo-Gu;Kim, Sung-Gil;Kang, Sun-Mee;Ko, Han-Seok
    • Speech Sciences
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    • v.5 no.1
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    • pp.7-21
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    • 1999
  • This paper proposes an improved training procedure in speech recognition based on the continuous density of the Hidden Markov Model (CDHMM). Of the three parameters (initial state distribution probability, state transition probability, output probability density function (p.d.f.) of state) governing the CDHMM model, we focus on the third parameter and propose an efficient algorithm that determines the p.d.f. of each state. It is known that the resulting CDHMM model converges to a local maximum point of parameter estimation via the iterative Expectation Maximization procedure. Specifically, we propose two independent algorithms that can be embedded in the segmental K -means training procedure by replacing relevant key steps; the adaptation of the number of mixture Gaussian p.d.f. and the initialization using the CDHMM parameters previously estimated. The proposed adaptation algorithm searches for the optimal number of mixture Gaussian humps to ensure that the p.d.f. is consistently re-estimated, enabling the model to converge toward the global maximum point. By applying an appropriate threshold value, which measures the amount of collective changes of weighted variances, the optimized number of mixture Gaussian branch is determined. The initialization algorithm essentially exploits the CDHMM parameters previously estimated and uses them as the basis for the current initial segmentation subroutine. It captures the trend of previous training history whereas the uniform segmentation decimates it. The recognition performance of the proposed adaptation procedures along with the suggested initialization is verified to be always better than that of existing training procedure using fixed number of mixture Gaussian p.d.f.

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The Effects of Research and Development Expenditure on the Firm Value: Focusing on the Portfolio's Excess Return

  • Choi, Shi Yeong;Kim, Kun Woo
    • Asia Pacific Journal of Business Review
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    • v.1 no.2
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    • pp.37-62
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    • 2017
  • To analyze the effects of R&D expenditure on the firm value of Korean firms, we classified portfolios based on R&D activity levels. After that, we conducted a time-series analysis to assess excess returns from the portfolios. To carry out such an analysis, an empirical analysis of excess returns in the capital market was performed by using the monthly earning rate of stocks from 2000 to 2013. The purpose of this research is to provide basic data on investment to stakeholders in the capital market by analyzing the effects of R&D on the firm value and to overcome scholarly limitations by offering a new model of analysis. The criteria for classifying the portfolios were based on R&D expenditure levels. The analysis models follow the Fama-French Three-Factor Model and the Carhart Four-Factor Model. The analyses results are as follows. Extrapolating monthly profit rates based on R&D expenditure levels, portfolios with low R&D expenditures showed higher earning rates than those with high R&D expenditures. This suggests that high R&D expenditures did not translate into high earning rates. The investor depreciates the R&D expenditures related profitability and the possibility of success in the market, leading to falls in stock prices and a failure to give a positive effect on the firm value. Our research differs from the previous investigations as we carried out an empirical analysis based on the actual investors' attitudes about R&D expenditures and how these can generate excess earnings. Our research results show that the data related to R&D expenditure are not reflected fully in the market.