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Interactions Between Genetic Risk Score and Healthy Plant Diet Index on Cardiometabolic Risk Factors Among Obese and Overweight Women

  • Fatemeh Gholami;Mahsa Samadi;Niloufar Rasaei;Mir Saeid Yekaninejad;Seyed Ali Keshavarz;Gholamali Javdan;Farideh Shiraseb;Niki Bahrampour;Khadijeh Mirzaei
    • Clinical Nutrition Research
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    • v.12 no.3
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    • pp.199-217
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    • 2023
  • People with higher genetic predisposition to obesity are more susceptible to cardiovascular diseases (CVDs) and healthy plant-based foods may be associated with reduced risks of obesity and other metabolic markers. We investigated whether healthy plant-foods-rich dietary patterns might have inverse associations with cardiometabolic risk factors in participants at genetically elevated risk of obesity. For this cross-sectional study, 377 obese and overweight women were chosen from health centers in Tehran, Iran. We calculated a healthy plant-based diet index (h-PDI) in which healthy plant foods received positive scores, and unhealthy plant and animal foods received reversed scores. A genetic risk score (GRS) was developed based on 3 polymorphisms. The interaction between GRS and h-PDI on cardiometabolic traits was analyzed using a generalized linear model (GLM). We found significant interactions between GRS and h-PDI on body mass index (BMI) (p = 0.02), body fat mass (p = 0.04), and waist circumference (p = 0.056). There were significant gene-diet interactions for healthful plant-derived diets and BMI-GRS on high-sensitivity C-reactive protein (p = 0.03), aspartate aminotransferase (p = 0.04), alanine transaminase (p = 0.05), insulin (p = 0.04), and plasminogen activator inhibitor 1 (p = 0.002). Adherence to h-PDI was more strongly related to decreased levels of the aforementioned markers among participants in the second or top tertile of GRS than those with low GRS. These results highlight that following a plant-based dietary pattern considering genetics appears to be a protective factor against the risks of cardiometabolic abnormalities.

Application of Photogrammetry Method to Measurement of Ground-Surface Displacement on the Slope (사면의 지표변위계측을 위한 사진측량기법의 적용)

  • Han, Jung-Geun;Bae, Sang-Ho;Oh, Da-Young
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.4 no.3
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    • pp.10-18
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    • 2001
  • The existing measurement system to ground-surface displacement survey of the slope has been including the hazard for the measure in site and the difficulty for install, maintenance and control of expensive instruments, which are impossible of whole survey on the slope surface. To overcome of those defects, Softcopy Photogrammertry method is used, which can measure displacement of ground-surface on the slope and structure deformation vectors. Recently, the survey methods applying the advantages of Photogrammetry and Digital Photogrammetry Survey are widely used. In this study, therefore, the development and application of the new instrument mechanism on the the site example are studied. Through the application of Softcopy Photogrammetry, the 3-D data of ground surface on the dangerous slope could be effectively obtained at the long distance, which are obtained through the reform process of contour line. Those are different to the results of the Close-Range Photogrammetry analysis. In ground instrumentation parts, the new practical system shall be the technical base to improve of the instrument machine as well as can be widely applied in civil engineering and others branch.

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The Influence of Medium Frequency Currents According to Frequency on Sensory Threshold (중주파 전류의 주파수가 감각 역치에 미치는 영향)

  • Yu, Jin-Ho;Hwang, Tae-Yeon;Jeong, Jin-Gyu
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.7 no.1
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    • pp.23-27
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    • 2009
  • Purpose : The purpose of this study was to examine the effects of different medium frequency currents on afferent fibers. Methods : Thirty healthy volunteers who had no known history of neurological disorders were equally assigned to one of three groups; 2500Hz, 4000Hz, and control and each group was applied to the left wrist in palmer cutaneous branch of radial nerve by different medium frequency currents for 15 min. We measured the changes of thresholds for tactile, two-point discrimination, and thresholds for pain. Results : The results showed that the medium frequency currents stimulation increased thresholds for tactile, two-point discrimination, and thresholds for pain. However, there is no statistically significant difference between group 2500Hz and group 4000Hz. Conclusion : This may explain thresholds for tactile, two-point discrimination, and thresholds for pain plain medium frequency currents stimulation inhibits the excitability of afferent fibers, but the effect of the frequency difference within medium frequency currents is not demonstrated.

Pressure analysis in grouting and water pressure test to achieving optimal pressure

  • Amnieh, Hassan Bakhshandeh;Masoudi, Majid;Kolahchi, Reza
    • Geomechanics and Engineering
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    • v.13 no.4
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    • pp.685-699
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    • 2017
  • In order to determine the rate of penetrability, water pressure test is used before the grouting. One of the parameters which have the highest effect is pressure. Mathematical modeling is used for the first time in this study to determine the optimum pressure. Thus, the joints that exist in the rock mass are simulated using cylindrical shell model. The joint surroundings are also modeled through Pasternak environment. In order to validate the modeling, pressure values obtained by the model were used in the sites of Seymareh and Aghbolagh dams and the relative error rates were measured considering the differences between calculated and actual pressures recorded in these operations. In water pressure test, in Seymareh dam, the error values were equal to 4.75, 3.93, 4.8 percent and in the Aghbolagh dam, were 22.43, 5.22, 2.6 percent and in grouting operation in Seymareh dam were equal to 9.09, 32.50, 21.98, 5.57, 29.61 percent and in the Aghbolagh dam were 2.96, 5.40, 4.32 percent. Due to differences in rheological properties of water and grout and based on the overall results, modeling in water pressure test is more accurate than grouting and this error in water pressure test is 7.28 percent and in grouting is 13.92 percent.

Numerical investigation on the bifurcation of natural convection in a horizontal concentric annulus (수평동심환상공간내 자연대류의 다중해에 관한 수치적 연구)

  • Jeong, Jae-Dong;Kim, Chan-Jung;Lee, Jun-Sik;Yu, Ho-Seon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.21 no.2
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    • pp.252-263
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    • 1997
  • Steady-state two-dimensional natural convective heat transfer in horizontal cylindrical annuli was studied by solving the governing equations based on the primitive variables. Emphasis was put on the occurrence of the multiple solutions at a given set of parameter values, and on the determination of the bifurcation points at which those multiple solutions begin to branch out. The multicellular flow pattern from the results of melting process in an isothermally heated horizontal cylinder for high Rayleigh numbers, was used as initial guesses for the field variables. This was succeeded in new bifurcation point to tetracellular solutions for an identical set of parameter variables of previous works. The close examination of flow pattern transition around bifurcation point was also conducted. It was found that the mechanisms of flow transition are different depending on the critical Rayleigh number of bifurcation point.

Analysis of Ventricular Septal Defect (심실중격결손증의 외과적 고찰)

  • 신제균
    • Journal of Chest Surgery
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    • v.18 no.2
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    • pp.151-156
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    • 1985
  • A clinical analysis was done on 50 cases of ventricular septal defect, operated from April 1981 to March 1984 at the department of Thoracic and Cardiovascular Surgery, School of Medicine, Keimyung University. Among 50 cases, 34 cases were males and 16 cases were females. Their age ranged from 1 to 26 years and the mean age was 9.7 years. The main symptoms at admission were frequent upper respiratory infection [50%], exertional dyspnea [42%] and palpitation [34%]. In anatomical classification by Kirklin, type I constituted 20%, type II 76%, type IV 4%. Associated congenital cardiac lesions were pulmonic stenosis [6 cases], patent foramen ovale [5 cases], aortic insufficiency [3 cases] and persistent left superior vena cava [1 case]. When a normal electrocardiogram pattern was present, Qp/Qs, Rp/Rs and pulmonary artery systolic pressure and Pp/Ps were relatively low. Among cases of above 1 cm2/M2 BSA in size of defect, Pp/Ps and pulmonary artery systolic pressure were increased than the cases of below 1 cm2/M2 BSA [P=0.01]. The postoperative right bundle branch block was occurred in 21 cases [75%] among 28 cases of right ventriculotomy approach. The operative mortality was 2% [1 case] among 50 cases and complication rate was 14% [7 cases].

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Adaptive Mean Value Cross Decomposition Algorithms for Capacitated Facility Location Problems (제한용량이 있는 설비입지결정 문제에 대한 적응형 평균치교차분할 알고리즘)

  • Kim, Chul-Yeon;Choi, Gyung-Hyun
    • Journal of Korean Institute of Industrial Engineers
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    • v.37 no.2
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    • pp.124-131
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    • 2011
  • In this research report, we propose a heuristic algorithm with some primal recovery strategies for capacitated facility location problems (CFLP), which is a well-known combinatorial optimization problem with applications in distribution, transportation and production planning. Many algorithms employ the branch-and-bound technique in order to solve the CFLP. There are also some different approaches which can recover primal solutions while exploiting the primal and dual structure simultaneously. One of them is a MVCD (Mean Value Cross Decomposition) ensuring convergence without solving a master problem. The MVCD was designed to handle LP-problems, but it was applied in mixed integer problems. However the MVCD has been applied to only uncapacitated facility location problems (UFLP), because it was very difficult to obtain "Integrality" property of Lagrangian dual subproblems sustaining the feasibility to primal problems. We present some heuristic strategies to recover primal feasible integer solutions, handling the accumulated primal solutions of the dual subproblem, which are used as input to the primal subproblem in the mean value cross decomposition technique, without requiring solutions to a master problem. Computational results for a set of various problem instances are reported.

An Impedance Transformer with Unequal Split Based on S-Parameter Conversion (S-파라미터 변환을 통한 비대칭 분배되는 임피던스 변환기)

  • Kim, Young
    • Journal of Advanced Navigation Technology
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    • v.20 no.4
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    • pp.361-366
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    • 2016
  • This paper presents an arbitrary impedance transformer with unequal split, based on S- to admittance parameter conversion. When compared even/ odd- mode analysis, the parameter conversion design method constitutes a simple design method to include phase delay information and arbitrary port impedances and asymmetrical configurations. To validate this design method, we designed a 50 to $12.5{\Omega}$ impedance transformer with a 3:1 unequal power split, at an operating frequency of 1 GHz. To implement the proposed impedance transformer, the low impedance transmission lines of calculated result are fabricated by the transmission line connected shunt open stub. Good experimental performances were obtained, in full agreement with simulated results.

몽산 덕이와 고려 인물들과의 교류

  • 남권희
    • Journal of Korean Library and Information Science Society
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    • v.21
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    • pp.363-399
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    • 1994
  • This article aims at bibliographical analysis of the and historical research of Buddhism in the period of king ChungYeul. The analysis is made in the respects of: 1) physical form 2) historical aspect of the Zen Buddhism in the latter period of Koryo Dynasty 3) related persons who corresponded with Mongsan First, this books is consist of 56 records about tripitaka, biography of Mongsan, poets of Zen Buddhism, and abstracts of Buddhist books. Secondly, the new trends of Buddhism in the 13th century was influenced by Mongsan Son(contemplate school, zen). He was corresponded with some political persons and the elite class of Koryo Buddhism. Because of these meetings, LimJae Son were adopted main stream of zen Buddism in Koryo Dynasty by Mongsan and his accompanies. Thirdly, these political groups want to meet Mongsan and his teaching about zen Buddism, but he suggest three questions to the gourp instead of meeting. And he explained 10 kinds of methods to study zen Buddism comparing visited ten persons with ten pinetrees. In the Koryo Dynasty, Buddism was very inportant in history of throughts and social functions. But there had been little research on Mongsan who afford theoretical base on zen Buddism in Chosun Dynasty. On the point of the relation to Koryo and Yuan dynasty in zen Buddism. The is a new and important records that afford some solutions of religious branch and trends in early periods of Chosun Dynasty.

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Thermal Sensor Allocation and Placement Algorithm on FPGA Based Design (FPGA 기반 설계의 온도 센서 최적 배치 알고리즘)

  • Hyeon, Cheol-Hwan;Nam, Hyoung-Wook;Kim, Yong-Ju;Kim, Tae-Whan
    • Proceedings of the Korean Information Science Society Conference
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    • 2008.06b
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    • pp.292-297
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    • 2008
  • 본 논문은 FPGA 기반 설계에서 주변보다 급격한 온도 변화를 보이는 hotspot들을 탐지하기 위한 열 감지 센서 수를 정하고, 센서의 놓여야 할 배치 장소를 결정하는 알고리즘을 제안한다. 열 감지 센서로는 동적으로 설계가 가능한 ring oscillator 센서 기술을 사용한다는 가정 하에, 센서의 사용 개수를 최소화함과 동시에 최적의 센서 배치 위치 찾는다. 기존의 연구의 단점은 센서가 감지하는 영역 범위를 적당한 크기의 정사각형으로 간주하였기에, 실제 원형의 관측 범위를 보이는 센서 감지 영역의 현실을 올바로 반영하지 못하였으며, 또한 잘 알려진 회로 분할(partition) 기법에 의존한 휴리스틱으로 최적의 결과를 보장하지는 못하였다. 이와는 달리 본 연구에서는 센서의 관측 범위를 원형으로 할 수도 있게 함과 동시에 최적의 해를 보장하는 센서 할당 및 배치 알고리즘을 제안한다. 구체적으로 본 제안 알고즘에서는 소위 “Candidate Coloring 기법”을 통해 센서가 놓여야 할 모든 후보 영역을 표시하며, “Candidate Filtering 기법”을 통해 불필요한 후보 영역들을 완전히 삭제하여 탐색 공간을 줄이게 되며 (해의 최적 해는 항상 유지 되도록 하면서), 마지막으로 Branch-and-Bound 알고리즘을 적용해 최적의 센서 할당 및 배치 결과를 찾아내었다.

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