• 한국임상수의학회지
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• 제15권2호
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• pp.410-416
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• 1998

These experiments were designed to evaluate the possibility of brain-stem auditory evoked responses(BAER) as a diagnostic tool for deafness in dogs. The BAER was recorded from three different groups of dogs; the normal dogs,'dog with otitis externa and dogs with unilateral destruction of cochlear. BAER of the normal dogs was consisted of distinct five peaks(I, II, III-IV, V). Furthermore, the clear shapes of waveform were observed at 85 dB. The latency of BAER was increased with reducing the intensity of sound-stimulus. The highest threshold of BAER was measured at 2 KHz with 10-30 dB. Dog with otitis externs demonstrated unclear shapes of BAER compared to the that of normal dogs. In the dogs with unilateral destruction of cochlear, the flat and indistinct waveform of BAER was recorded from the cochlear destroyed ear while that of BAER from normal side of ears did not show any differences from the normal BAER. These results indicate that the BAER can be clinically used in order to diagnose the deafness in dogs.

• 대한의용생체공학회:의공학회지
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• 제3권2호
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• pp.105-112
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• 1982

Using electronic cochlear implant system, we studied in cats the difference in the response of the brain stem evoked response (BER) during the stimulation with the acoustic signals and the electric signals. These brain stem electric responses were analyzed using the integral pulse frequency modulation method of the auditory nervous system. Animal experimental results and the analysis show that the carrier wave hasimprored the frequency specificity. of the electronic auditory prosthesis.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 심포지엄 논문집 정보 및 제어부문
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• pp.141-142
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• 2008

Hearing loss is the most common birth defect among infants. Yet most hearing-impaired children are not identified until 1 to 3 years of age - which is well beyond the critical period(6 month) for healthy speech and language development. However, if a hearing-impairment is identified and treated in its early stages, child's speech and language skills will be comparable to his or her normal- hearing peers. For these reasons, hearing screening at birth and routinely throughout childhood is extremely important. Auditory brain-stem response(ABR) is nowadays one of the most reliable diagnostic tools in the early detection of hard of hearing. In this study, we developed the system that detects auditory evoked potential using micro-processor. Furthermore, it is required to develop a portable system to measure in not only soundproof room but also nursery for infants.

• Journal of Korean Neurosurgical Society
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• 제39권3호
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• pp.183-187
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• 2006

Objective : Hemifacial spasm has characteristic and specific electrophysiological finding, lateral spread response[LSR]. We study the correlation between change of lateral spread response during microvascular decompression[MVD] and clinical outcome after MVD. Methods : Sixty two patients with hemifacial spasm who were treated with microvascular decompression from March 2000 to February 2003 were included in this study. The monitoring of intraoperative facial electromyography[EMG] and brain stem auditory evoked potential were performed. Results : In 28 [44.7%] patients, there was persistence of lateral spread response after vascular decompression in root exit zone of facial nerve. Among these 28 patients, 9 had mild hemifacial spasm at discharge. Three out of 34 patients who had intraoperative disappearance of lateral spread response after MVD had mild hemifacial spasm. But Both groups, disappearance of LSR [Group I], and persistence [Group II] had only 2 patients with mild hemifacial spasm, and 5 patients at 3 months, respectively. Conclusion : Although intraoperative EMG monitoring is very useful in assessing the efficacy of MVD, the clinical outcome of MVD in patient with hemifacial spasm does not always correlate with EMG finding. The prognostic value of intraoperative LSR monitoring in the long-term results is questionable.

• Clinical and Experimental Pediatrics
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• 제60권11호
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• pp.353-358
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• 2017

Purpose: To develop and evaluate a simple screening tool to assess hearing loss in newborns. A derived score was compared with the standard clinical practice tool. Methods: This cohort study was designed to screen the hearing of newborns using transiently evoked otoacoustic emission and auditory brain stem response, and to determine the risk factors associated with hearing loss of newborns in 3 tertiary hospitals in Northern Thailand. Data were prospectively collected from November 1, 2010 to May 31, 2012. To develop the risk score, clinical-risk indicators were measured by Poisson risk regression. The regression coefficients were transformed into item scores dividing each regression-coefficient with the smallest coefficient in the model, rounding the number to its nearest integer, and adding up to a total score. Results: Five clinical risk factors (Craniofacial anomaly, Ototoxicity, Birth weight, family history [Relative] of congenital sensorineural hearing loss, and Apgar score) were included in our COBRA score. The screening tool detected, by area under the receiver operating characteristic curve, more than 80% of existing hearing loss. The positive-likelihood ratio of hearing loss in patients with scores of 4, 6, and 8 were 25.21 (95% confidence interval [CI], 14.69-43.26), 58.52 (95% CI, 36.26-94.44), and 51.56 (95% CI, 33.74-78.82), respectively. This result was similar to the standard tool (The Joint Committee on Infant Hearing) of 26.72 (95% CI, 20.59-34.66). Conclusion: A simple screening tool of five predictors provides good prediction indices for newborn hearing loss, which may motivate parents to bring children for further appropriate testing and investigations.

• 전자공학회논문지SC
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• 제46권2호
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• pp.15-21
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• 2009

난청은 가장 흔한 선천성 장애이다. 이 질병의 발생 빈도는 신생아 1000명 출생 당 $1{\sim}3$명 정도로 상당히 높다. 이러한 청력 장애가 조기에 발견된다면 수술적인 치료 등으로 예방할 수 있으나, 그렇지 못할 경우 언어와 학습장애를 초래하게 된다. 이런 관점을 근거로 신생아를 대상으로 한 선천성 난청의 선별검사는 큰 의미를 가지며 난청환자의 조기발견을 위한 노력이 필수적이라 할 수 있다. 기존의 수동 청력검사 시스템은 신생아 청력 평가 시 검사자의 주관성에 의존하게 되므로, 청성뇌간 반응의 뇌파 분석이 잘못될 가능성이 커진다. 따라서 본 연구에서는 난청여부를 자동으로 판독하여 결과를 나오도록 개발하고자 하였으며, 또한 기존 제품들과 차별화하기 위하여 휴대용으로 개발하여 차폐실이 아닌 일반 병실에서도 검사가 가능하도록 함에 따라 유소아의 청각 장애를 극복시키는데 기여하고자 하였다.