• 동의생리병리학회지
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• 제25권3호
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• pp.551-557
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• 2011

The purpose of this study is to investigate the relation between brachial-ankle pulse wave velocity and the features of metabolic syndrome, and differences according to sex in patients diagnosed cerebral infarction. The study group comprised 61 patients over age 30 who were diagnosed cerebral infarction, accompanied with metabolic syndrome. The brachial-ankle pulse wave velocity, blood pressure, lipid profiles, fasting blood glucose, body mass index were measured. Also we checked past history of patients. Then we analyzed the association between brachial-ankle pulse wave velocity and the features of metabolic syndrome. Pearson correlation analysis reflected the variables affecting the brachial-ankle pulse wave velocity as follows : Age, SBP(systolic blood pressure), DBP(diastolic blood pressure), FBS(fasting blood glucose) were positively correlated. As a result of regression analysis, in patients with cerebral infarction accompanied with metabolic syndrome, the brachial-ankle pulse wave velocity is affected by age to men, SBP, FBS, DBP to women. The brachial-ankle pulse wave velocity is not affected by the components of metabolic syndrome, except blood pressure, FBS, in patients with ischemic stroke.

• 한국산학기술학회논문지
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• 제20권2호
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• pp.673-680
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• 2019

본 연구는 2016년 4월 1일부터 2016년 10월 31일까지 종합병원 건강검진센터에 내원한 435명을 대상으로 혈장 호모시스테인 농도가 정상 호모시스테인 군과 무증상 고호모시스테인 군 간에 발목-상완 pulse wave velocity에 유의한 차이가 있는지를 비교해 심혈관 질환 발생의 향후 예측인자로서 호모시스테인 검사와 동맥의 경직도를 간접적으로 반영하는 상완-발목 pulse wave velocity의 직접적인 상호 연관성을 비교해보고자 시도되었다. 연구결과 고 호모시스테인혈증 군에서 정상 호모시스테인 군에 비해 연령, 허리둘레, BUN, 혈장 크레아티닌이 유의하게 높았고, HDL은 유의하게 낮았다. 또한, 고 호모시스테인혈증은 흡연 및 음주 여부와 관련이 있었으며, 남성에서 유의하게 많았다. 관련 변수를 보정하기 전에는 고 호모시스테인 군에서 우측 및 좌측 상완-발목 맥파 속도가 유의하게 높았으나 관련 변수를 보정한 후에는 두 군의 상완-발목 맥파 속도는 유의한 차이를 보이지 않았다. 따라서, 향후 국내 수검자를 대상으로 호모시스테인 농도를 낮추는 중재적 치료 후 심혈관질환 예방에 대한 독립적 연관성 및 호모시스테인과 신장 기능의 관련성에 대한 추가 연구가 필요하겠다.

• 대한임상검사과학회지
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• 제47권1호
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• pp.28-34
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• 2015

Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring arterial stiffness. Increased arterial stiffness measured by PWV stands for progressive arteriosclerosis and is caused by atherosclerotic risk factors. This study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to the leading risk factors for arteriosclerosis or atherosclerosis. Subjects were 114, 69 males and 45 females who are in 60's and had baPWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbA1c, total cholesterol, BSBP (brachial artery systolic blood pressure), BDBP (brachial artery diastolic blood pressure), CSBP (central artery systolic blood pressure), CDBP (central artery diastolic blood pressure), augmentation index (AIx) and diabetes mellitus. Correlation analysis between baPWV and atherosclerotic risk factor showed significant relationship in age, HbA1c, LDL cholesterol, BSBP, BDBP, CSBP, CDBP and augmentation index. baPWV was independently related to age and BSBP in multiple linear regression analysis. The group with increased arterial stiffness was independently related to BDBP in multiple logistic regression analysis. This study might be meaningful in evaluating the relationship between arterial stiffness and atherosclerotic risk factor in a new way, and be helped to make various studies for cardiovascular disease.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2009년도 추계학술대회
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• pp.441-443
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• 2009

Piezo Film Sensor를 이용하여 팔뚝의 상완 동맥에서 맥박 측정을 위한 센서부 최적 구조에 관한 연구를 하였다. 탈부착이 쉬운 팔뚝형 밴드 형태에 Piezo Film Sensor를 삽입하여 생체 신호를 측정 하였다. 센서부의 최적 구조를 알기 위해서 센서패드 구조물의 형태에서 매질 및 두께를 변화시켜 가면서 생체 신호의 크기를 비교하였다.

• Archives of Plastic Surgery
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• 제49권6호
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• pp.755-759
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• 2022

Brachial artery aneurysms are rare diseases that may be caused by infection or trauma. We report a case of a 71-year-old man who presented with a mass in his right antecubital fossa that increased in size slowly over time. Three years ago, the patient underwent ascending and total-arch replacement with artificial vessel graft to treat aortic root and ascending aorta aneurysm. Preoperative physical examination of right upper extremity showed a nonpulsatile mass with normal pulse of axillary, brachial, and radial arteries. The mass was removed and brachial artery reconstruction was done initially using saphenous vein graft. Two months later, the patient revisited with recurrent pseudoaneurysm, involving the bifurcation point of brachial artery. Aneurysm was totally resected and the brachial artery was reconstructed by interposition graft using a bifurcated GORE-TEX artificial vessel graft. The patient healed without complication and no recurrence was observed. Artificial vessel graft is an available option for reconstruction, and revascularization of vessel defect after excision of brachial artery aneurysm may involve bifurcation point.

• 한국방사선학회논문지
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• 제13권6호
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• pp.873-878
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• 2019

뇌혈관 질환은 우리나라의 주요 10대 사망 원인 중 3대 사인에 해당하며, 이러한 질환은 동맥경화와 관련이 있으므로 동맥경화를 예측할 수 있는 인자의 진단 방향의 제시가 필요하다. 본 논문에서는 연령대별 상완-발목동맥 맥파전달속도와 뇌동맥 혈관 협착 및 혈압, 비만도, 복부비만과의 유의성을 평가하였으며, 뇌동맥 혈관 협착과 연령대별 유의성 평가는 50대의 연령대에서만 유의한 결과를 나타내었으며, 동맥경화의 위험인자인 혈압, 비만, 복부비만의 경우 전체 연령대에서 유의한 결과를 나타내었다. 그리고 상완-발목동맥 맥파전달속도가 상승하였을 경우, 뇌동맥 혈관 협착은 전체 1,376명중 788명으로 57.2%의 분포를 나타내었으며, 위험인자인 혈압의 경우, 전체 7,557명중 3,255명으로 43%, 비만도는 2,708로 35.8%, 복부비만은 2,941명으로 38.9%의 분포를 나타내었다. 이러한 결과를 통하여 상완-발목동맥 맥파전달속도 검사 시, 동맥경화가 의심된다면 우선적으로 뇌동맥 혈관 협착을 의심하고 뇌동맥 혈관 검사를 시행할 것을 권한다. 동맥경화의 위험인자인 혈압, 비만, 복부비만과의 유의성 평가를 통하여 향 후 유사 연구 시, 기초자료로 활용될 것이라고 사료된다.

• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.777-785
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• 2007

In this paper, Finger-Toe Index (FTI) is proposed as an analytic parameter for the characterization of arterial vessel. Different from the currently being employed pulse wave velocity (PWV) information of the volume pulse wave measured from 4 arterial channels, the proposed FTI uses the ratio of the shorter of the two up-stroke time of PPG from fingers ($UT_{finger}$) and that of PPG (Photoplethysmography) from toes ($UT_{toe}$). To verify the usefulness of the proposed method, Finger-Toe Indexes were derived from the volume pulse waves acquired from 50 people under examination aged from 12 to 81 years old, and they were then compared with blood pressure ankle-brachial index (ABI). It was successfully demonstrated that the arterial stiffness can be estimated with respect to age and FTI is more strongly correlated with the pulse transit time than ABI. From the regression analysis, we also found that FTI has significant correlation PWV for a quantitative index of arterial stiffness and provides more accurate information than ABI for the characterization of arterial vessel.

• Nutrition Research and Practice
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• 제11권4호
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• pp.327-333
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• 2017

BACKGROUND/OBJECTIVES: Complications of diabetes, such as cardiovascular disease, are associated with increased mortality among type 2 diabetes mellitus patients. Homocysteine has been recently identified as a predictor of cardiovascular disease-related complications in diabetes. We investigated whether or not supplementation with folic acid tablets can lower homocysteine levels and improve parameters related with vascular complications. SUBJECTS/METHODS: We conducted a non-randomized 8-week trial involving postmenopausal diabetic women (n = 25) supplemented with $800{\mu}g$ of folic acid ($400{\mu}g$ twice a day) daily. Subjects' serum levels of folate, homocysteine, and vitamin $B_{12}$ were measured, along with vascular function and brachial-ankle pulse wave velocity. RESULTS: Folic acid supplementation significantly increased serum folate levels (P < 0.0001), reduced homocysteine levels (P < 0.0001), and increased vitamin $B_{12}$ levels (P = 0.0063). There were significant decreases in low-density lipoprotein cholesterol levels as well as the ratios of low-density lipoprotein cholesterol to high-density lipoprotein cholesterol and total cholesterol to high-density lipoprotein cholesterol. Brachial-ankle pulse wave velocities were not altered by supplementation. Changes in serum vitamin $B_{12}$ after folic acid supplementation were negatively correlated with changes in brachial-ankle pulse wave velocity. CONCLUSIONS: In this study on postmenopausal Korean women with type 2 diabetes mellitus, folic acid supplementation reduced serum homocysteine levels, increased serum folate and vitamin $B_{12}$ levels, and lowered lipid parameters.

• 대한임상검사과학회지
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• 제46권4호
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• pp.143-149
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• 2014

Pulse wave velocity (PWV) is used to non-invasively estimate the severity of arteriosclerosis by measuring the patient's arterial stiffness comparing with each normal reference range according to their ages. Increased arterial stiffness is closely related to both atherosclerosis and arteriosclerosis, which have been known for causes of cardiovascular disease and stroke, also negatively affects the prognosis and the re-occurrence in patients with stroke. The study is focused on how brachial-ankle pulse wave velocity (baPWV) is related to cardiovascular disease risk factors in patients with acute stroke. There were 114 subjects, 69 males and 45 females, all in their 60's and had PWV test for acute stroke. The results are as follows: the group with increased arterial stiffness showed significant increase in HbAlc, total cholesterol, RSBP (resting systolic blood pressure), CSBP (central systolic blood pressure) and CDBP (central diastolic blood pressure). Cross tabulation test showed that there was a significant relationship only between the group with increased arterial stiffness and diabetes mellitus (DM). Therefore, it might be useful for preventing re-occurrence and making a favorable prognosis to promptly adjust DM and hypertension-related risk factors in patients with acute stroke.

• 한국방사선학회논문지
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• 제8권5호
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• pp.271-278
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• 2014

상완신경총에서 STIR(short TI inversion recovery) 지방소거 강조영상과 SPAIR(spectral adiabatic inversion recovery) T2, T1 지방소거 강조영상기법을 비교 평가하여 최적의 지방소거 기법을 알아보고자 하였다. 총 30 명 상완신경총에 질환이 없는 정상인 지원자를 대상으로 3.0 T MRI 기기를 이용하여 검사를 하였고, 분석방법으로 세 기법에 대하여 SNR, CNR 및 4단계 점수로 평가를 하였다. 정량적 분석 결과로 SPAIR T1 기법에 대한 SNR, CNR 값은 상완신경총기시부($03.07{\pm}0.98$, $-2.25{\pm}0.54$), 상완신경총몸체($06.70{\pm}1.81$, $36.31{\pm}2.17$)에서 높은 값을 제공하였다 (p<0.05). 정성적 분석결과 상완신경총 묘출도와 지방소거 정도, 영상의 인공물은 SPAIR T1($3.2{\pm}0.70$, $3.6{\pm}0.51$, $3.4{\pm}0.10$)기법이 의미 있게 높게 나타났다(p<0.05).