• Journal of Korea Entertainment Industry Association
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• v.6 no.4
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• pp.82-92
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• 2012

Recently people who enjoy social game via mobile devices significantly are increasing depending on the rapid adoption of smart phones and the development of the network such as LTE. Most of them are enjoying the casual gaming mobile social games that you are able to play easily, but social issues like health problems due to long play time are emerging. The users, however, do not last long because of the simplicity of the game, and there are few people who actually buy game items even though they play it long time. This study has been conducted aiming to overcome such difficulties. This study suggests ways to generate constantly revenue avoiding short-term box-office after the release of mobile social games based on the analysis for market trend and profitability of the mobile social game. In addition, by applying profitability model analyzed to Japan's most successful game practices, this paper suggests the concrete methods about the commitment of the users. For summarizing the main achievements of this paper, providing the latest market information about mobile social games, analysis of profitability, practical implications for the commitment of the users are presented.

• Journal of Microbiology and Biotechnology
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• v.33 no.9
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• pp.1206-1212
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• 2023

The Wnt/β-catenin pathway plays essential roles in regulating various cellular behaviors, including proliferation, survival, and differentiation [1-3]. The intracellular β-catenin level, which is regulated by a proteasomal degradation pathway, is critical to Wnt/β-catenin pathway control [4]. Normally, casein kinase 1 (CK1) and glycogen synthase kinase-3β (GSK-3β), which form a complex with the scaffolding protein Axin and the tumor suppressor protein adenomatous polyposis coli (APC), phosphorylate β-catenin at Ser45, Thr41, Ser37, and Ser33 [5, 6]. Phosphorylated β-catenin is ubiquitinated by the β-transducin repeat-containing protein (β-TrCP), an F-box E3 ubiquitin ligase complex, and ubiquitinated β-catenin is degraded via a proteasome pathway [7, 8]. Colorectal cancer is a significant cause of cancer-related deaths worldwide. Abnormal up-regulation of the Wnt/β-catenin pathway is a major pathological event in intestinal epithelial cells during human colorectal cancer oncogenesis [9]. Genetic mutations in the APC gene are observed in familial adenomatous polyposis coli (FAP) and sporadic colorectal cancers [10]. In addition, mutations in the N-terminal phosphorylation motif of the β-catenin gene were found in patients with colorectal cancer [11]. These mutations cause β-catenin to accumulate in the nucleus, where it forms complexes with transcription factors of the T-cell factor/lymphocyte enhancer factor (TCF/LEF) family to stimulate the expression of β-catenin responsive genes, such as c-Myc and cyclin D1, which leads to colorectal tumorigenesis [12-14]. Therefore, downregulating β-catenin response transcription (CRT) is a potential strategy for preventing and treating colorectal cancer. Plant cytokinins are N⁶-substituted purine derivatives; they promote cell division in plants and regulate developmental pathways. Natural cytokinins are classified as isoprenoid (isopentenyladenine, zeatin, and dihydrozeatin), aromatic (benzyladenine, topolin, and methoxytopolin), or furfural (kinetin and kinetin riboside), depending on their structure [15, 16]. Kinetin riboside was identified in coconut water and is a naturally produced cytokinin that induces apoptosis and exhibits antiproliferative activity in several human cancer cell lines [17]. However, little attention has been paid to kinetin riboside's mode of action. In this study, we show that kinetin riboside exerts its cytotoxic activity against colon cancer cells by suppressing the Wnt/β-catenin pathway and promoting intracellular β-catenin degradation.

• Geophysics and Geophysical Exploration
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• v.26 no.4
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• pp.211-228
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• 2023

Ground-penetrating radar (GPR) surveys are commonly used to monitor embankments, which is a nondestructive geophysical method. The results of GPR surveys can be complex, depending on the situation, and data processing and interpretation are subject to expert experiences, potentially resulting in false detection. Additionally, this process is time-intensive. Consequently, various studies have been undertaken to detect cavities in GPR survey data using deep learning methods. Deep-learning-based approaches require abundant data for training, but GPR field survey data are often scarce due to cost and other factors constaining field studies. Therefore, in this study, a deep- learning-based model was developed for embankment GPR survey cavity detection using data augmentation strategies. A dataset was constructed by collecting survey data over several years from the same embankment. A you look only once (YOLO) model, commonly used in computer vision for object detection, was employed for this purpose. By comparing and analyzing various strategies, the optimal data augmentation approach was determined. After initial model development, a stepwise process was employed, including box clustering, transfer learning, self-ensemble, and model ensemble techniques, to enhance the final model performance. The model performance was evaluated, with the results demonstrating its effectiveness in detecting cavities in embankment GPR survey data.

• Korea Trade Review
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• v.48 no.2
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• pp.217-243
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• 2023

This study revealed practical implications by analyzing the clauses and disputable issues of the Korea Service Contract. Korea introduced Servcie Contract in the container part since Hanjin Shipping's bankrupcy and distributed the standard form(2019). After that, the standard form was revised during the supply chain crisis(2022). In the standard form, there are clause that require agreement due to conflicting interests of shipper and carrier. Therefore, the main clauses of the standard form were analyzed to derive the practical meaning to the both parties. In addition, in the process of introducing the standard form, the most disputable issues, liquidated damages and minimum quality commitment, were deeply analyzed to explain how shipper and carriers' benefit and loss differ as the clause changes. In conclusion, both parties must set LD at a very reasonable level so that they do not proceed separately with penalty. In addition, 'evenly' is a much more important than quantity for carrier in the establishment of MQC, so extra box option for shipper even during the peak season is needed to accommodate with service contract.

• Journal of Environmental Health Sciences
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• v.49 no.6
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• pp.334-343
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• 2023

Background: South Korea's Act on Registration and Evaluation, etc. of Chemicals (known as K-REACH) was established to protect public health and the environment from hazardous chemicals. 4,4'-Methylenedianiline (MDA), which is used as a major intermediate in industrial polymer production and as a vulcanizing agent in South Korea, is classified as a toxic substance under the K-REACH act. Although MDA poses potential ecological risks due to industrial emissions and hazards to aquatic ecosystems, no ecological risk assessment has been conducted. Objectives: The aim of this study is to assess the ecological risk of MDA by identifying the actual exposure status based on the K-REACH act. Methods: Various toxicity data were collected to establish predicted no effect concentrations (PNECs) for water, sediment, and soil. Using the SimpleBox Korea v2.0 model with domestic release statistical data and EU emission factors, predicted environmental concentrations (PECs) were derived for ten sites, each referring to an MDA-using company. Hazard quotient (HQ) was calculated by ratio of the PECs and PNECs to characterize the ecological risk posed by MDA. To validate the results of modeling-based assessment, concentration of MDA was measured using in-site freshwater samples (two to three samples per site). Results: PNECs for water, sediment, and soil were 0.000525 mg/L, 4.36 mg/kg dw, and 0.1 mg/kg dw, respectively. HQ for surface water and sediment at several company sites exceeded 1 due to modeling data showing markedly high PEC in each environmental compartment. However, in the results of validation using in-site surface water samples, MDA was not detected. Conclusions: Through an ecological risk assessment conducted in accordance with the K-REACH act, the risk level of MDA emitted into the environmental compartments in South Korea was found to be low.

• Journal of the Korea institute for structural maintenance and inspection
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• v.27 no.6
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• pp.138-143
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• 2023

In this study, the crack healing performance of each crack healing agent manufacturing method was analyzed by adding crack healing agents in the form of alginate gel and spore suspension inoculated with endospores of calcium carbonate-forming bacteria to mortar. In addition, by applying it to an full-scale structure in the form of a box-type culvert, we attempted to create an environment in which the developed crack healing agent can be applied not only to a laboratory environment but also to an actual field. The crack healing agent using the dry heat drying method showed crack healing performance, but in the case of the freeze drying method, many spores were killed by freeze hardening and therefore the crack healing performance was lost. As a result of SEM and XRD pattern analysis of the presumed crack healing material extracted from the crack of a full-scale structure, it was found to be calcite, one of the calcium carbonate crystals produced by microorganisms applied to the crack healing agent. In conclusion, it was found that the crack healing by microorganisms can be implemented in a real structure.

• Korean Chemical Engineering Research
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• v.61 no.4
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• pp.542-549
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• 2023

Since the growing interest in surrogate modeling, there has been continuous research aimed at simulating nonlinear chemical processes using data-driven machine learning. However, the opaque nature of machine learning models, which limits their interpretability, poses a challenge for their practical application in industry. Therefore, this study aims to analyze chemical processes using Explainable Artificial Intelligence (XAI), a concept that improves interpretability while ensuring model accuracy. While conventional sensitivity analysis of chemical processes has been limited to calculating and ranking the sensitivity indices of variables, we propose a methodology that utilizes XAI to not only perform global and local sensitivity analysis, but also examine the interactions among variables to gain physical insights from the data. For the ammonia synthesis process, which is the target process of the case study, we set the temperature of the preheater leading to the first reactor and the split ratio of the cold shot to the three reactors as process variables. By integrating Matlab and Aspen Plus, we obtained data on ammonia production and the maximum temperatures of the three reactors while systematically varying the process variables. We then trained tree-based models and performed sensitivity analysis using the SHAP technique, one of the XAI methods, on the most accurate model. The global sensitivity analysis showed that the preheater temperature had the greatest effect, and the local sensitivity analysis provided insights for defining the ranges of process variables to improve productivity and prevent overheating. By constructing alternative models for chemical processes and using XAI for sensitivity analysis, this work contributes to providing both quantitative and qualitative feedback for process optimization.

• Journal of the Korean Society of Marine Environment & Safety
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• v.29 no.6
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• pp.620-627
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• 2023

Ship noise is one of the important factors for the living and health of seafarers, and ef orts to reduce ship noise are actively underway. There are two methods of noise reduction: passive noise Control (PNC) and active noise control (ANC). Unlike cars and airplanes, ANC is not widely used for noise reduction on ships. This study aimed to reduce the noise generated in the engine room by using soundproof panels and high-frequency vibration generators, as well as active noise control (ANC). For this purpose, an experimental model was made using an acrylic box, and the noise reduction effect was measured under four conditions. The experimental results are as follows: First, the soundproof panel had a noise reduction effect in all ranges from 55 dB to 85 dB. In the case of using a high-frequency vibration generator, there was no ef ect in the low noise range such as 55 dB(A), but there was a noise reduction effect in the high noise range such as 70.8 dB(A) and 85 dB(A).Second, when the soundproof panel and the high-frequency vibration generator were used simultaneously, the noise reduction ef ect was up to -2.2 dB(A). The results of this experiment were obtained from an experimental model made of acrylic, and they may be different from actual ships made of steel plate. In future studies, we plan to experiment using iron plate (considering the material, thickness, and structure) used in actual ships. We hope that this study will help to improve the living environment and health of seafarers on ships.

• Communications of Mathematical Education
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• v.37 no.3
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• pp.329-348
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• 2023

This study is necessary for the stable settlement of the 2022 revised mathematics curriculum 'data and possibility' area. This study was conducted centering on literature analysis. The purpose of this study is to realize statistics education in line with the 2022 revised mathematics curriculum. This purpose was achieved by examining the statistics learning contents of the 2022 revised curriculum, analyzing Chinese mathematics curriculum, and analyzing Chinese mathematics textbooks. In this study, the following studies were conducted. First, five elements were extracted through the analysis of the 'statistics and probability' area of the Chinese mathematics curriculum. The extracted elements are the 4th grade goals, synthesis and practice content areas, achievement standards for statistics and probability (6), (9), and (11). Second, examples presented in Chinese mathematics textbooks and Chinese curriculum appendices related to the extracted elements were analyzed. Regarding the 4th grade goal, the statistical problem-solving process of the 7th grade 2nd semester mathematics textbook was analyzed. Regarding the synthesis and practice content area, the data analysis unit of the 8th grade 2nd semester mathematics textbook was analyzed. In relation to the achievement standard (6), Example 85 of the curriculum appendix was analyzed, in relation to the achievement standard (9), Example 86 was analyzed, and in relation to the achievement standard (11), Example 87 was analyzed. Third, based on the analysis results, implications for the development of new curriculum and 'textbook development, teaching and learning methods' according to the 2022 revised middle school mathematics curriculum were derived. Through the results of this study, we expect the successful realization of the 2022 revised middle school mathematics and curriculum statistics education.

• Resources Recycling
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• v.33 no.1
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• pp.69-76
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• 2024

In an effort to achieve the goal of carbon neutrality, countries around the world are aiming to phase out coal-fired power plants. Due to various reasons, electricity production through coal-fired power generation and sulfur oxide (SOx) emissions are expected to continue in the future. In the South Korea, sodium bicarbonate (NaHCO₃) and lime materials are used to treat SOx, and most of the sodium bicarbonate is imported. Therefore, this research was conducted to replace sodium bicarbonate by improving the physical properties of lime materials using domestic limestone. Limestone was heat-treated through a box-type electric furnace and a vertical electric furnace. Due to the structural characteristics of the vertical electric furnace, a lime material(quicklime) was possible to improve the physical properties like a specific surface area and a pore volume. Then, they were reached to 22.33 m²/g specific area and 0.14 cc/g pore volume.