• Title/Summary/Keyword: box

Search Result 6,629, Processing Time 0.038 seconds

Temporal Regulation of Ovine Interferon-tau Gene by the Transcription Factor Eomesodermin in the Peri-Implantation Period

  • Kim, Min-Su;Lim, Hyun-Joo;Lee, Ji Hwan;Hur, Tae Young;Son, Jun Kyu
    • Journal of Animal Reproduction and Biotechnology
    • /
    • v.34 no.4
    • /
    • pp.292-299
    • /
    • 2019
  • Interferon tau (IFNT) regulation, an anti-luteolytic factor produced by conceptuses of the ruminant ungulates, is essential for the maintenance of early pregnancy, but a definitive mechanism for its temporal transcription has not been elucidated. We and others have observed the T-box protein eomesodermin (EOMES) exhibited high mRNA expression in the ovine embryonic trophectoderm; thus, both caudal-relatedhomeobox-2 (CDX2) and EOMES coexist during the early stages of conceptus development. Objective of this study was to examine the effect of EOMES on ovine IFNT gene transcription when evaluated with CDX2, ETS2 and AP1 transcription factors implicated in the control of cell differentiation in the trophectoderm. In this study, quantitatively via reverse transcription-polymerase chain reaction (RT-PCR) analysis between ovine trophoblast cells was initially performed, finding that transcription factors CDX2 and 'EOMES transcription factor mRNAs' were specific to trophectoderm cells. These mRNAs were also found in days 15, 17, and 21 ovine conceptuses. Furthermore, human choriocarcinoma JEG3 cells (trophoblast cell line) were cotransfected with an ovine IFNT (-654bp)-luciferase reporter (-654-oIFNT-Luc) construct and several transcription factor expression plasmids. Cotransfection of the reporter construct with CDX2, ETS2 and AP1 increased transcription of -654-oIFNT-Luc by about 11-fold compared with transfection of the construct alone. When cells were initially transfected with EOMES followed by transfection with CDX2, ETS2 and/or AP1, the expression of -654-oIFNT-Luc was decreased. Also, EOMES factor inhibited the stimulatory activity of CDX2 alone. These results suggest that when conceptuses attach to the uterine epithelium, ovine IFNT gene transcription is down-regulated by an increase of EOMES factor expression in the attached ovine trophoblast cells.

KoDSat System Level EMC(Electro Magnetic Compatibility) Test and an Analysis of the Test Results (검증위성 시스템레벨 전자기파(EMC) 시험 및 결과에 대한 분석)

  • Seo, Min-Seok;Park, Seok-Jun;Sim, Eun-Seop;Kim, Se-Yeon;Chae, Jang-Su
    • Journal of the Korean Society for Aeronautical & Space Sciences
    • /
    • v.34 no.4
    • /
    • pp.102-109
    • /
    • 2006
  • In this paper, the system level EMC radiated emission test results of KoDSat(Korea Demonstration Satellite), its affects upon the Launch vehicle and H/W improving methods regarding its over exceed value of EMC specification are discussed. Regarding its over exceed value, we estimated that DAU of KoDSat generated the exceeded EMC noise source, and these test results were analyzed using the EMC2000 tool to find out how did it affect the FTS(Flight Termination Subsystem) of KSLV-1(Korea Small Launch Vehicle). To diminish the EMC noise source of UHF(430.1Mhz) band level, we redesigned the DAU power board to be applied the various schemes for EMI noise reduction such as grounding, shielding and EMI filtering, and also verified these reworks to analyze its diminishing affects in UHF band level by means of performing the DAU box level EMC test and performing the second KoDSat's system level EMC test.

Design of PFRP I and Box Shape Compression Members Considering Stress Distribution in the Cross-section (단면 내 응력분포를 고려한 I형 및 Box형 단면의 PFRP 압축재의 설계)

  • Choi, Jin-Woo;Kim, Jae-Wook;Joo, Hyung-Joong;Yoon, Soon-Jong
    • Journal of the Korean Society for Advanced Composite Structures
    • /
    • v.2 no.1
    • /
    • pp.15-22
    • /
    • 2011
  • Pultruded fiber reinforced polymeric plastic (PFRP) structural members may be one of attractive alternatives of the structural members in the civil engineering applications because of its many advantageous mechanical properties. However, they have relatively low modulus of elasticity and also cross-sections of structural shapes are composed of thin plate components such as flange and web. Therefore, structural stability is an important issue in the design of pultruded structural compression members. For the design of pultruded structural member under compression, buckling and post-buckling strengths of plate components may be taken into account. In the structural steel design following AISC/LRFD, in addition to the buckling strength, the nonuniform stress distribution in the section is incorporated with a form factor. In this paper, the form factor for the design of PFRP structural member under compression is investigated through the analytical study. Furthermore, the process for the determination of the form factor is suggested.

The Formative Characteristics of Hats Shown in Prêt-à-porter Collection (프레타포르테 컬렉션에 나타난 모자의 조형적 특성)

  • Yoo, Hyun Jeong;Kim, Jeong Mee
    • Journal of the Korea Fashion and Costume Design Association
    • /
    • v.18 no.4
    • /
    • pp.141-158
    • /
    • 2016
  • The objective of this study is to examine the type and characteristics of hat, and also to analyze the formative characteristics of hats shown in $Pr{\hat{e}}t-{\grave{a}}$-porter Collection. The literature review focused on the relevant technical books and preceding researches while the case study targeted 1,561 photos of hats shown in the 'Donga TV Collection'. The research range was from the S/S season of 2012 to the F/W season of 2015/16. The results of this study are as follows. 1. A hat is composed of crown and brim. In the results of classifying hats based on it, there were 572 crown-type hats, 533 hat-type, 219 cap-type, 156 irregular-type, and 81 brim-type in the order. 2. For the crown-type hats, they were mainly like cylindrical-type, bell-type, dome-type, and circle-type, using colors like black, beige, brown, red, mustard, and grey, and materials like wool, fur, velvet, straw, and metal while they were decorated with bead or lace. 3. For the hat-type hats, they were mainly like bell-type, ladder-type, and hemisphere-type, using colors like peach, white, gold, brown, and khaki, and materials like silk, cotton, straw, and wool while they were decorated with feather and ribbon. 4. For the cap-type hats, they were mainly like hemisphere-type, using colors like white, black, khaki, mustard, and purple, and materials like fur, leather, and wool while they were decorated with wappen and chain. 5. For the irregular-type hats, they were mainly like sandglass-type, box-type, animal-type, trumpet-type, and bell-type, using colors like purple, orange, pink, yellow, and sky-blue, and materials like metal, feather, mesh, plastic, straw, and linen while they were decorated with ribbon, net, bell, and flower. 6. For the brim-type visor, they were mainly like square-type, using colors like transparent, yellow, and black, and materials like plastic, cotton, leather, and metal.

  • PDF

An Analysis of Ordinary Mail Service Quality Attributes using Kano Model and Decision Tree Model (카노모형에서 의사결정나무모형을 이용한 통상우편서비스 품질속성 분석)

  • Choi, Hyeon Deok;Riew, Moon Charn
    • Journal of Korean Society for Quality Management
    • /
    • v.44 no.4
    • /
    • pp.883-895
    • /
    • 2016
  • Purpose: The demand for ordinary mail services supplied by 'Korea POST' is decreasing due to the opening of mail service market and the growth of alternative communication media such as e-mail and SNS. To overcome this situation it is urgent to introduce new services that can be able to appeal customers and to improve existing services. Methods: A field survey is conducted to corporate customers who send ordinary mails and individual customers who receive these mails, respectively. Quality attributes of ordinary mail services are classified by two-dimensional perspectives in terms of Kano model. Decision tree model is utilized for classifying the quality attributes. Comparative analyses are done whether there are perceived differences on each quality attributes between corporate customers and individual customers. Results: Quality attributes such as 'discount postal charges', 'sending small packages by simply dropping it into a mail box', 'sending a mail of any appearance', 'delivering a mail anywhere', and 'receiving a mail at a preferred time where a customer is located ' are classified differently according to some market segments, while most of the quality attributes are classified as attractive or one-dimensional. Conclusion: Decision tree model has been found to be most effective to classify quality attributes for each market segment especially when trying to classify quality attributes belonging to 'gray areas'. Based on the perceived differences on quality attributes among customers, strategic implications are suggested to obtain potential customers and to have competitive advantages.

Differentiation of Chest of Drawers in Traditional Furniture - Focusing on Korea, Japan, and the West - (전통 가구의 서랍장 비교 - 한국, 일본, 서구 중심으로 -)

  • Moon, Sun-Ok
    • Journal of the Korea Furniture Society
    • /
    • v.22 no.2
    • /
    • pp.101-111
    • /
    • 2011
  • The intention is to explore the differentiation or evolution of the chest of drawers in traditional Korean, Western, and Japanese furniture in order to know how the drawers currently becoming popular in Korea were developed historically. The Korean furniture centered in $Jang$, $Nong$, and $Bandazi$ used in the tradition generally, the Western furniture involved in drawers, and the Japanese furniture called $Tansu$ in Japanese called the chest of drawers were focused on the study because the Western and Japanese drawers affected the development of the chest of drawers in Korean furniture during the late 19th century and the Japanese Ruling Era, respectively. As a result, the Korean furniture was not shown the chest of drawers but only small drawers that store small items located in the upper part of $Jang$, $Nong$, and $Bandazi$ mostly used as wardrobe, while the traditional Japanese furniture developed from Edo period (1607-1868) had showed a wide variety of chest of drawers like $Isho-dansu$, $Mizuya-dansu$, $Kusuri-dansu$, $Cho-dansu$, $Funa-dansu$, $Kaidan-dansu$, $Nagamochi-dansu$, $Kuruma-dansu$, and so on, for specialized storage. And in the traditional Western furniture were presented the chest like a large-box form, mule chest, chest of drawers, cabinet, commode, highboy, tallboy, wardrobe, secretary drawer and bureau with document drawer invented and evolved throughout the 15th-18th century. Therefore, the chest of drawers in contemporary Korean furniture is supposed to adopt the Japanese and Western drawer form and to ensure the continual production from the obvious utility of the design with decoration for our current everyday lives.

  • PDF

Robust Response Transformation Using Outlier Detection in Regression Model (회귀모형에서 이상치 검색을 이용한 로버스트 변수변환방법)

  • Seo, Han-Son;Lee, Ga-Yoen;Yoon, Min
    • The Korean Journal of Applied Statistics
    • /
    • v.25 no.1
    • /
    • pp.205-213
    • /
    • 2012
  • Transforming response variable is a general tool to adapt data to a linear regression model. However, it is well known that response transformations in linear regression are very sensitive to one or a few outliers. Many methods have been suggested to develop transformations that will not be influenced by potential outliers. Recently Cheng (2005) suggested to using a trimmed likelihood estimator based on the idea of the least trimmed squares estimator(LTS). However, the method requires presetting the number of outliers and needs many computations. A new method is proposed, that can solve the problems addressed and improve the robustness of the estimates. The method uses a stepwise procedure, suggested by Hadi and Simonoff (1993), to detect outliers that determine response transformations.

Reliability Analysis for Fatigue Damage of Steel Bridge Details (강교 부재의 피로손상에 대한 신뢰성 해석)

  • Park, Yeon Soo;Han, Suk Yeol;Suh, Byoung Chal
    • Journal of Korean Society of Steel Construction
    • /
    • v.15 no.5 s.66
    • /
    • pp.475-487
    • /
    • 2003
  • This study developed an analysis model of estimating fatigue damage using the linear elastic fracture mechanics method. Stress history occurring to an element when a truck passed over a bridge was defined as block loading and crack closure theory explaining load interaction effect was applied. Stress range frequency analysis considering dead load stress and crack opening was done. Probability of stress range frequency distribution was applied and the probability distribution parameters were estimated. The Monte Carlo simulation of generating the probability various of distribution was performed. The probability distribution of failure block numbers was obtained. With this the fatigue reliability of an element not occurring in failure could be calculated. The failure block number divided by average daily truck traffic remains the life of a day. Fatigue reliability analysis model was carried out for the welding member of cross beam flange and vertical stiffener of steel box bridge using the proposed model. Consequently, a 3.8% difference was observed between the remaining life in the peak analysis method and in the proposed analysis model. The proposed analysis model considered crack closure phase and crack retard.

A Study of Seismic Resistant Design for Base-Isolated Bridges(II) (지진에 대비한 기초분리 교량의 설계법에 관한 연구(II))

  • Lee, Sang Soo;Yu, ChulSoo
    • Journal of Korean Society of Steel Construction
    • /
    • v.9 no.4 s.33
    • /
    • pp.637-647
    • /
    • 1997
  • As stated in Part(I), the use of the isolator is meant to protect a structure from seismic risk, by concentrating the inelastic deformations to relatively cheap and replaceable devices while the rest of the structures remains elastic. This research has been carried out to investigate the effects of various structural parameters and isolator characteristics on the seismic response of Base Isolated Bridges. Simplified analysis method for practical design is developed by using the results. The Proposed Code-Type approach method can be used to estimate the inertial forces accurately, not only at the isolator but throughout the height of the Base-Isolated Bridges. The proposed method is recommended to use in preliminary design tool or even a final design tool for Base Isolated Bridges. For the validation of simplified design method, examples with artificial earthquake time history and design response spectrum for P.C Box Bridge with bilinear hysteretic steel damper are evaluated.

  • PDF

A Study on the Geometric Parameters that Influence the Shear Buckling of Trapezoidally Corrugated Webs (제형파형강판의 전단거동에 영향을 미치는 기하학적 요소에 대한 연구)

  • Gill, Heung Bae;Lee, Seung Rok;Lee, Hak Eun;Lee, Pil Goo
    • Journal of Korean Society of Steel Construction
    • /
    • v.15 no.5 s.66
    • /
    • pp.591-601
    • /
    • 2003
  • Because of their high out-of-plane and in-planes strength, trapezoidally corrugated plates have been increasingly used in buildings and bridges. If corrugated plates are used as the web of plate girders or prestressed concrete box girders, the flanges take most of the bending stress. On the other hand, the corrugated plate web supports shear stress due to the accordion effect. The corrugated plate web could fail by three different buckling modes: global, local, or interactive shear buckling. To determine the effects of geometric parameters on the buckling capacity of the corrugated plates, a parametric study was performed using finite dement method. The analysis results showed that the buckling capacity and modes depend on individual parameters as well as combinations of parameters.