• 대한한방내과학회지
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• 제43권5호
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• pp.960-966
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• 2022

Objectives: Irritable bowel syndrome is a functional disorder of the gastrointestinal tract marked by chronic abdominal pain and altered bowel habits. Irritable bowel syndrome is experienced by 11% of the global population. Although antidepressants and antispasmodic agents are currently used as therapeutic methods, they have side effects, so safer treatment agents are needed. Hence, I report the case of an outpatient who suffers from irritable bowel syndrome. Methods: The patient visited a public health center 14 times over four weeks and was treated with acupuncture and herbal medicine (Sosiho-tang and Jakyakgamcho-tang). Treatment progress was assessed using the Irritable Bowel Syndrome Severity Scoring System. Results: After 28 days of treatment, the Irritable Bowel Syndrome Severity Scoring System score decreased from 410 to 30 points without adverse events. The patient was highly satisfied. Conclusion: Sosiho-tang and Jakyakgamcho-tang with acupuncture might become recommended therapeutic options for irritable bowel syndrome patients.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7967-7973
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• 2015

Background: The abrupt rise of colorectal cancer in developing countries is raising concern in healthcare settings. Studies on assessing relationships with modifiable and non-modifiable risk factors in the Pakistani population have been limited. The present investigation was designed to examine associations of dietary practices, addictive behavior and bowel habits in developing colorectal cancer (CRC) among patients in a low-resource setup. Materials and Methods: An age-gender matched case control study was conducted from October 2011 to July 2015 in Karachi, Pakistan. Cases were from the surgical oncology department of a public sector tertiary care hospital, while their two pair-matched controls were recruited from the general population. A structured questionnaire was used which included questions related to demographic characteristics, family history, dietary patterns, addictive behavior and bowel habits. Results: A family history of cancer was associated with a 2.2 fold higher chance of developing CRC. Weight loss reduced the likelihood 7.6 times. Refraining from a high fat diet and consuming more vegetables showed protective effects for CRC. The risk of CRC was more than twice among smokers and those who consumed Asian specific addictive products as compared to those who avoid using these addictions (ORsmoking: 2.12, 95% CI: 1.08 - 4.17, ORpan: 2.92, 95% CI: 1.6 - 5.33, ORgutka: 2.13, 95% CI: 1.14 - 3.97). Use of NSAID attenuated risk of CRC up to 86% (OR: 0.14, 95% CI: 0.07 - 0.31). Conclusions: Most of the findings showed concordance with the literature elucidating protective effects of consuming vegetables and low fat diet while documenting adverse associations with family history, weight loss, constipation and hematochezia. Moreover, this study highlighted Asian specific indigenous addictive products as important factors. Further studies are needed to validate the findings produced by this research.

• The Korean Journal of Pain
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• 제32권2호
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• pp.69-78
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• 2019

Pain therapy often entails gastrointestinal adverse events. While opioids are effective drugs for pain relief, the incidence of opioid-induced constipation (OIC) varies greatly from 15% to as high as 81%. This can lead to a significant impairment in quality of life, often resulting in discontinuation of opioid therapy. In this regard, a good doctor-patient relationship is especially pivotal when initiating opioid therapy. In addition to a detailed history of bowel habits, patient education regarding the possible gastrointestinal side effects of the drugs is crucial. In addition, the bowel function must be regularly evaluated for the entire duration of treatment with opioids. Furthermore, if the patient has preexisting constipation that is well under control, continuation of that treatment is important. In the absence of such history, general recommendations should include sufficient fluid intake, physical activity, and regular intake of dietary fiber. In patients of OIC with ongoing opioid therapy, the necessity of opioid use should be critically reevaluated in terms of an with acceptable quality of life, particularly in cases of non-cancer pain. If opioids must be continued, lowering the dose may help, as well as changing the type of opioid. If these measures do not suffice, the next step for persistent OIC is the administration of laxatives. If these are ineffective as well, treatment with peripherally active ${\mu}$-opioid receptor antagonists should be considered. Enemas and irrigation are emergency measures, often used as a last resort.

• Journal of Korean Biological Nursing Science
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• 제11권2호
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• pp.167-175
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• 2009

Purpose: The purpose of this study was to examine the prevalence and factors on Irritable Bowel Syndrome (IBS) symptoms in university students. Methods: This study was descriptive survey research. The subjects were 187 university students from one university. The exclusion criteria were 1) had GI surgery 2) had severe physiologic or psychologic problems 3) had liver, bile duct, pancreatic, and intestinal disease that required treatment. The ROME III was used to diagnose IBS. Sociodemographic characteristics, general health state by SF-36, psychological health by SCL-90-R, stress by perceived stress scale, sleep disturbance by Korean sleep scale, and diet habits were measured. Data were analyzed by using SPSS 17.0. Results: Seventeen students (9.1%) had IBS by ROME III criteria, but 46% had some GI problems at that time. Abdominal pain or discomfort continued for last six months or more in 14.3%. Fiber intake, obsessive-compulsiveness, hostility, psychoticism, global severity index, positive symptom distress, role physical, bodily pain, social functioning, and mental health were significantly different between IBS group and Non IBS group. Conclusion: Over nine percent of the students were diagnosed by Rome III criteria, and almost half of them had some GI problems. Diet, personality, general health state, and psychological health were factors of IBS.

• Advances in pediatric surgery
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• 제2권1호
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• pp.46-52
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• 1996

일부 국가에서만 발병 예가 보고된 바 있는 신생아의 국한적인 원발성소장염전을 수술하여 생존시킨 2예를 보고하였다. 진단적인 소견은 갑자기 발병한 신생아 소장폐쇄 소견과 패혈증 및 1예에서만 보인 장관출혈 외에는 특기할 만 한 것이 없었으나 이러한 질환의 가능성을 염두에 두고 신속히 개복술을 시행함이 환자를 살리기 위하여 가장 중요한 점으로 판단되었다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제38권
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• pp.10.1-10.5
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• 2016

Herniation after harvesting of deep circumflex iliac artery (DCIA) flap is a known but not a common complication. It occurs about 2.8 to 9 % according to the literatures and can proceed to a more severe complication such as bowel obstruction. There are several factors that exacerbate the risk: surgical factors, operator factor, and patient factors. Surgical factors include large anatomical defect and denervation of related muscles. Operator factor stands for unpunctual suture technique. Patient factors represent obesity, diabetes, pulmonary disease, smoking habits, and so on. Thus, herniation might occur regardless of meticulous suture. Herein, we would like to report two cases of herniation after DCIA flap harvesting and repaired by Lichtenstein tension-free hernioplasty with literature review.

• Childhood Kidney Diseases
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• 제19권1호
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• pp.1-7
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• 2015

Coexisting voiding and bowel dysfunction in children are common in the clinic. The idea that overactive bladder (OAB) and constipation arise from one single pathophysiology has been reinforced in many studies. In Korea, a nationwide multicenter study conducted in 2009 showed that overall prevalence of OAB in children, 5-13 years of age, was 16.59% and this number has increased more recently. The initial step to manage coexisting fecal retention and OAB in children is to characterize their bowel and bladder habits and to treat constipation if present. Although diagnosing constipation in children is difficult, careful history-taking using the Bristol Stool Form Scale, and a scoring system of plain abdominal radiography, can help to estimate fecal retention more easily and promptly. Non-pharmacological approaches to manage functional constipation include increasing fluids, fiber intake, and physical activity. Several osmotic laxatives are also effective in improving OAB symptoms and fecal retention. Additionally, correction and education in relation to toilet training is the most important measure in treating OAB with fecal retention.

• Journal of Neurogastroenterology and Motility
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• 제24권4호
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• pp.536-543
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• 2018

Culture forms an integral aspect of environmental factors which influences disease presentation and clinical outcomes in functional gastrointestinal disorders (FGIDs). In this review, the role of culture in FGIDs in the East is briefly explored with regards to symptom presentation and diagnostic issues, lifestyle and cultural habits, epidemiology, and healthcare seeking behavior. In both functional dyspepsia and irritable bowel syndrome, symptom presentation and disease sub-typing in Asians are known to differ from their Western counterparts, possibly relating to cultural dietary practices and from cultural perception of symptoms. Dietary patterns, together with defecating practices are explored as factors contributing to a lower prevalence of constipation in the East. An urban-rural difference in the prevalence of FGIDs in Asia is attributed to a change in dietary patterns in rapidly developing urban communities, together with an increased level of psychological morbidity. Lastly, cultural attitudes towards traditional/local remedies, variation in healthcare systems, anxiety regarding organic disease, and religious practices have been shown to influence healthcare seeking behavior among FGID patients in the East.

• Journal of Nutrition and Health
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• 제42권8호
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• pp.702-713
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• 2009

대학생들의 변비유병률과 배변습관을 알아보고 영양소섭취 상태를 알아보고자 인천지역 대학교에서 건강관련 교양강의를 듣는 수강생들을 대상으로 (남자 166명, 여자 187명) 설문조사와 신체계측 및 3일간 식이섭취 조사를 실시한 결과는 다음과 같다. 조사 대상자의 평균 연령은 남학생 23.5세, 여학생 20.9세이었으며, 자택에서 거주하는 비율이 가장 많았으며 자취, 기숙사, 하숙이나 친척집에 거주하는 순이었다. 남학생의 63.9%, 여학생의 63.1%는 21~40만원의 용돈을 받고 있었고 지난 2개월 동안 남학생의 45.2%, 여학생의 47.1%는 체중을 유지하고 있었다. 로마기준 II를 이용하여 조사한 기능성 변비유병률은 남녀 각각 12.7%, 28.9%, 자의적 변비 유병률은 남녀 각각 12.0%, 36.9%로 여학생이 남학생에 비해 유의적으로 높았으며 일반사항에 따른 기능성 변비와 자의적 변비의 차이는 보이지 않았다. 자의적 변비 중 남학생의 35.0%, 여학생의 44.9%만이 기능성 변비의 진단기준에 부합하였고, 본인은 변비가 아니라고 응답했지만 기능성 변비의 진단기준에 부합한 경우는 11.4%이었다. 본인이 변비라고 인식하는 경우 남학생의 94.7%, 여학생의 91.0%는 의료기관을 방문한 경험이 없었고 남학생은 모두 변비약이나 건강기능식품을 이용하고 있지 않았으며 여학생은 변비 완화를 위해 10.3%가 변비약, 11.8%가 건강기능식품을 복용하고 있었다. 배변습관 조사 결과 남학생의 75.3%, 여학생의 40.1%는 주 5회 이상 배변을 하고 있었고, 변의 양은 2 cup 이상이라고 응답한 경우가 남학생은 93.4%, 여학생은 75.9%로 남학생이 많은 경향을 보였다. 남녀 모두 대상자의 70%정도가 배변 후 상쾌하다고 하였으며 남학생의 49.4%, 여학생의 24.6%만이 규칙적으로 배변을 하였다. 신체계측치와 영양소 섭취량 분석 결과 기능성 변비와 자의적 변비 유무에 따른 차이는 보이지 않았으나 단백질의 경우 성별이나 변비 유무와 상관없이 RI에서 UL 사이로 섭취하는 비율이 가장 높았고, 남학생은 여학생에 비해 EAR 보다 낮게 섭취하는 비율이 유의적으로 높았다. 비타민 C, Vit $B_2$, 엽산, 칼슘, 아연의 섭취는 EAR 이하로 섭취하는 비율이 모두 50%를 넘어 영양소의 섭취량이 매우 낮음을 알 수 있었고 특히 엽산은 남녀 모두 95% 이상이 EAR 이하로 섭취하고 있어 섭취 부족이 심각하였다. 변비와 관련이 있는 것으로 알려진 식이섬유 섭취량은 1,000 kcal당 섭취량으로 환산에 남학생은 8.5 g, 여학생은 8.9 g으로 한국인 영양섭취기준의 식이섬유 충분섭취량에 훨씬 못 미치는 수준이었다. 여학생의 경우 기능성 변비의 유병률은 28.9%, 자의적 변비의 유병률은 36.9%로 조사되었는데, 본인은 변비가 아니라고 응답했지만 기능성 변비의 진단기준에 부합한 경우도 13.6%이며 본인이 변비라고 응답한 경우의 대다수는 의료기관 방문이나 약물, 기능성 식품 섭취 같은 노력도 하지 않고 있어 만성적 변비로 인한 질병의 위험이 우려된다. 또한 식이섬유 섭취를 비롯한 각종 영양소들도 균형 있는 섭취를 하고 있지 않아 이후 다가올 임신기와 수유기의 영양문제로 이어질 것이므로 올바른 영양섭취를 비롯한 적절한 영양교육이 활성화 되어야겠다.

• 한국식품영양과학회지
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• 제34권5호
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• pp.644-651
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• 2005

본 연구는 생약제와 식이섬유가 주성분인 다이어트 제제가 체중, 체지방, 혈액지질분획 및 배변습관에 미치는 영향을 알아보기 위하여 대학생 자원자 30명을 대상으로 5주 동안 실시하였다. 다이어트 제제는 1일 2회 섭취케 하되 본인의 일상 식사 및 생활양식을 그대로 유지케 하였으며 실험전 설문지 조사를 통한 대상자의 일반환경요인 평가와 식이섭취 평가가 실시되었다. 실험기간 중에는 주 3회 식이일지 작성과 매주 체중을 측정토록 하였고 실험 개시 일과 종료일에는 혈액채취와 신체계측이 실시되었다. 실험대상자의 특성을 보면 중산층 이상으로 평균 나이 21세로 정상체중을 유지하였다. 운동은 절어도 30분간, 주 $1\~2$회 이상하였고 음주율은 매우 높았으나 흡연은 거의 하지 않았다. 식사는 적어도 2끼 이상 먹는 편이나 외식빈도가 많았고 식습관이 불량하였으며 배변횟수는 보통이었으나 변비경험은 비교적 많았다. 영양소 섭취량은 전반적으로 낮았으며 실험개시기에 비해 종료시에 식이섭취 및 영양소 섭취량이 낮은 경향을 보였다. 체중, 체질량지수, 표준체중백분율은 물론 체지방비율, 피부지방두께, 허리둘레, 엉덩이 둘레 및 WHR등은 실험개시시에 비해 종료시 감소하였으며(p<0.05),반면에 근육량의 비율은 유의하게 증가하였다(p<0.05). 한편 혈액 총 콜레스테롤과 중성지방은 유의하게 감소하였으나(p<0.05) HDL-콜레스테롤농도는 변화가 없었고 LDL-콜레스테롤농도는 실험개시시에 비해 종료시 감소하는 경향을 보였다. 혈압은 실험 전과 후에 변화하지 않았다. 배변횟수는 실험 개시기에 비해 종료시에 증가하였다(p<0.05).위의 결과를 종합해 볼 때 본 연구의 생약제와 섬유질로 제조한 다이어트 제제가 체중과 체지방 및 비만관련 신체지표를 유의하게 감소시켰으며, 혈액 중 일부 지방분획과 배변횟수도 바람직하게 변화하였다. 그러나 더욱 통제된 후속 연구가 이뤄져야 할 것으로 사료된다.