• Korean Journal of Health Education and Promotion
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• v.22 no.1
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• pp.135-146
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• 2005

A total of 448 male students(220 college-bound students, 228 vocational students) were surveyed through a self-administered questionnaire in Daegu from November to December 2003. This study aimed to identify the pattern in cigarette smoking according to personality type and related factors to smoking. Among respondents, $30.8\%$ of college-bound students and $69.3\%$ of vocational students have ever smoked. The rate of current smoking was $9.2\%$ in the college-bound students and $56.6\%$ in the vocational students. Smoking experience and current smoking status was significantly associated in psychotic personality in the college-bound students and in extroversive and psychotic personality in the vocational student group. The logistic regression analysis revealed that smoking of parents, siblings, and friends were significant variables on the current smoking in the college-bound students, and smoking of friends and extroversive and psychotic personality in the vocational students. As a results, this study suggest that those students who have the factors identified in this study regarded as having the potential to start smoking, and they can be subject to anti-smoking programs to help them quell their desire for smoking or delay.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.12
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• pp.4993-4996
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• 2015

Background: To evaluate the efficacy and safety of albumin-bound paclitaxel-based chemotherapy in treatment for patients with advanced esophageal cancer who failed in first-line chemotherapy. Materials and Methods: We collected29 advanced esophageal cancer patients who received albumin-bound paclitaxel-based chemotherapy fromJune 2009 to September 2013, and the efficacy and safety of the compound were evaluated. These patients were treated with $100-150mg/m^2$ nab-paclitaxel on days 1,8. The cycle was repeated every 3 weeks. Clinical efficacy was evaluated every two cycles. Results: Of the 29 patients, two persons interrupted treatment because of adverse reactions, failed to evaluate efficacy effect. The rest of 27 patients who could be evaluated for short-term response, 10 patients (37%) achieved partial response, 2 (7.4%) remained stable disease, and 15 (55.6%) had progressivedisease. The objective response rate was 37%, and the disease control rate was 44.4%.The median time to progression was 6.6 months.The major adverse reactions includedalopecia (62.07%), neutropenia (65.5%), gastrointestinalreaction (10.3%) andsensory neuropathy(6.8%). Conclusions: The albumin-bound paclitaxel-based chemotherapy is efficacy and safety in treatment for patients with advanced esophageal cancer who failed in first-line chemotherapy.

• Journal of KIISE:Computer Systems and Theory
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• v.30 no.9
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• pp.477-486
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• 2003

In combinatorial auctions buyers nay bid for arbitrary combinations of goods. But determining the winners of combinatorial auctions who maximize the profit of a seller is known to be NP-complete. A branch-and-bound method can be one of practical algorithm for winner determination. However, bid selection heuristics play a very important role in the efficiency of a branch-and-bound method. In this paper, we designed and implemented an algorithm which used a branch-and-bound method and Linear Programming for winner determination in combinatorial auctions. We propose new bid selection heuristics which consider a branching bid and conflicting bids simultaneously to select a branching bid in the algorithm. In addition, upper bounds are reused to reduce the running time in specific cases. We evaluated the performance of the algorithm by experiments with five data distributions and compared our method with others. The algorithm using heuristics showed a superior efficiency in two data distributions and a similar efficiency in three distributions.

• Economic and Environmental Geology
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• v.27 no.5
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• pp.469-477
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• 1994

Many researchers have investigated most representative sequential extraction method using various reagents for determining the chemical forms of metals in soils and sediments. In this paper, a newly modified method for sequential extraction scheme based on Tessier's method by Environmental Geochemistry Research, Centre for Environmental Technology, Imperial College, was introduced and examined. In comparison with Tessier's method, originally designed for sediment analysis by Atomic Absorption Spectrophotometry (AAS), the sequential extraction scheme has been developed for the multi-element analysis by Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES). The partitioning of particulate trace elements was classified into five fractions: (i) exchangeable, (ii) bound to carbonates or specially adsorbed, (iii) bound to Fe and Mn oxides, (iv) bound to organic matter and sulphides and (v) residuals. The experimental results of the pilot study for in-house reference material (HRM2) and certified international standard reference material (SRM2711) using the modified method showed not only reasonable precision and accuracy but also acceptable overall recovery rates. In addition, mine dump soils sampled in the Dalsung Cu-W mine, Korea were prepared and sequentially extracted using the method. Most of Cu was bound to organic matter/sulphides and residual fractions. The dominant fraction of soil Pb and Zn in the study area was found in the residuals. The fraction of Cd showed a wide variation between samples and could be found bound to the carbonates or specially adsorbed, oxides, organic fraction and residuals. The recovery rates of Cd, however, were poor due to relatively low Cd concentrations in soils. The heavy metals in these mine dumps appear to be in the more inert forms and should not be readily bioavailable. The soils, however, had very low pH values (average 4.1) and had sandy textures; consequently, rapid infiltration of rainfall may increase leaching of Zn and Cd which were found to be around 5 to 10% of the exchangeable fraction. As a result of the investigation of this study, it has been strongly recommended that these mine waste materials should still be considered a significant contaminant source and will need environmental remediation to prevent pollutants from being released into the environment.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.12
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• pp.4305-4323
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• 2014

In this paper, we investigate the degrees of freedom (DOF) of the Y channel consisting of three single-antenna users and a two-antenna common access relay, where each user intends to exchange independent messages with the other two users with the assistance of the relay. We show that the DOF of this particular scenario is 1.5. In order to prove this result, we firstly derive a DOF upper bound based on cut-set bound by allowing cooperation among users, which shows that the total DOF is upper bounded by 1.5. Then we propose a novel transmission scheme based on asymmetric signal space alignment (ASSA) to demonstrate the achievability of the upper bound. Theoretical evaluation and numerical results confirm that the upper bound can be achieved by utilizing ASSA, which also proves the optimality of the ASSA-based scheme in terms of DOF. Combining the upper bound and achievability, we conclude that the exact DOF is 1.5. Moreover, we present a novel iterative joint beamforming optimization (I-JBO) algorithm to further improve the sum rate. Numerical simulations have been provided to demonstrate the convergence speed and performance advantage of the I-JBO algorithm.

• Ocean and Polar Research
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• v.32 no.3
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• pp.177-186
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• 2010

A sequential extraction technique was used to study sediment phosphorus speciation and its relative importance in the intertidal flat of Keunso Bay during summer and winter for a better understanding of the phosphorus cycle and bioavailability in intertidal sediments. Loosely sorbed P contents were the lowest among the five P-pools and showed little seasonal or spatial variation. Although Fe-bound P contents were almost constant in winter, they decreased rapidly with sediment depth in summer. The dissolution of Fe oxides, used as an oxidant for the anaerobic respiration, ascribed the rapid decrease of Fe-bound P in summer. Al-bound P contents displayed little seasonal variation, but showed a large spatial variation, with higher values in the upper intertidal flat. Comprising about 50% of total P, Ca-bound P contents were the highest among the five P-pools. Ca-bound P contents were higher in winter than summer, but did not exhibit a clear spatial variation. Organic P contents were higher in summer than winter, which was associated with higher primary production and clam biomass in summer. Organic P contents were higher in the lower intertidal flat than the upper intertidal flat. In Keunso Bay, bioavailable P contents of the intertidal flat comprising about one third of total P ranged from 2.41 to 5.09 ${\mu}molg^{-1}$ in summer and 3.82 to 5.29 ${\mu}molg^{-1}$ in winter. The bioavailability of P contents was higher in the lower intertidal flat than the upper intertidal flat, which was attributed to the large clam production in the lower intertidal flat.

• IMMUNE NETWORK
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• v.13 no.2
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• pp.63-69
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• 2013

IL-12 is a secretory heterodimeric cytokine composed of p35 and p40 subunits. IL-12 p35 and p40 subunits are sometimes produced as monomers or homodimers. IL-12 is also produced as a membrane-bound form in some cases. In this study, we hypothesized that the membrane-bound form of IL-12 subunits may function as a costimulatory signal for selective activation of TAA-specific CTL through direct priming without involving antigen presenting cells and helper T cells. MethA fibrosarcoma cells were transfected with expression vectors of membrane-bound form of IL-12p35 (mbIL-12p35) or IL-12p40 subunit (mbIL-12p40) and were selected under G418-containing medium. The tumor cell clones were analyzed for the expression of mbIL-12p35 or p40 subunit and for their stimulatory effects on macrophages. The responsible T-cell subpopulation for antitumor activity of mbIL-12p35 expressing tumor clone was also analyzed in T cell subset-depleted mice. Expression of transfected membranebound form of IL-12 subunits was stable during more than 3 months of in vitro culture, and the chimeric molecules were not released into culture supernatants. Neither the mbIL-12p35-expressing tumor clones nor mbIL-12p40-expressing tumor clones activated macrophages to secrete TNF-${\alpha}$. Growth of mbIL-12p35-expressing tumor clones was more accelerated in the $CD8^+$ T cell-depleted mice than in $CD4^+$ T cell-depleted or normal mice. These results suggest that $CD8^+$ T cells could be responsible for the rejection of mbIL-12p35-expressing tumor clone, which may bypass activation of antigen presenting cells and $CD4^+$ helper T cells.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.8
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• pp.3862-3888
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• 2017

In high diversity node situation, single-channel MAC protocols suffer from many collisions. To solve this problem, the research of multichannel MAC protocol has become a hotspot. And the cyclic quorum-based multichannel (CQM) MAC protocol outperformed others owing to its high frequency utilization. In addition, it can avoid the bottleneck that others suffered from and can be easily realized with only one transceiver. To obtain the accurate performance of CQM MAC protocol, a Markov chain model, which combines the channel hopping strategy of CQM protocol and IEEE 802.11 distributed coordination function (DCF), is proposed. The metrics (throughput and average packet transmission delay) are calculated in performance analysis, with respect to node number, packet rate, channel slot length and channel number. The results of numerical analysis show that the optimal performance of CQM protocol can be obtained in saturation bound situation. And then we obtain the saturation bound of CQM system by bird swarm algorithm (BSA). Finally, the Markov chain model and saturation bound are verified by Qualnet platform. And the simulation results show that the analytic and simulation results match very well.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.10
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• pp.697-704
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• 2013

The identification of haplotypes, which encode SNPs in a single chromosome, makes it possible to perform haplotype-based association tests with diseases. Minimum Error Correction model, one of models to computationally assemble a pair of haplotypes for a given organism from Single Nucleotide Polymorphism fragments, has been known to be NP-hard even for gapless cases. In the previous work, an improved branch and bound algorithm was suggested and showed that it is more efficient than naive branch and bound algorithm by performing experiments for Apis mellifera (honeybee) data set. In this paper, to show the extensibility of the algorithm to other organisms we apply the improved branch and bound algorithm to the human data set and confirm the efficiency of the algorithm.

• Journal of Radiation Protection and Research
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• v.23 no.1
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• pp.25-32
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• 1998

Tritium is released into the environment as various form but HTO is most relevant to the incorporation of tritium into living organisms and to the formation of OBT. Tritiated compounds may be transported to humans via several tropic levels. Retention times of organically bound tritium in organisms are considerably longer than those of tritiated water, which has significant consequences on exposure dose estimation. It is rather difficult to predict the amount of OBT produced by the photosynthetic process of plants because it may be influenced by a multitude of environmental factors and plant parameters. Tritiated organic matters are classified as the exchangeable or nonexchangeable bound tritium according to the bound form. After short term HTO exposure in plants, the formation and uptake of OBT were evaluated.