• Journal of Nutrition and Health
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• v.30 no.2
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• pp.201-209
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• 1997

The purpose of this study was to investigate the possible causal factors of obesity in women with child-bearing experiences in effects to provide optimal information for the prevention and/or treatment of obesity. Sventy one women with child-bearing experiences were divided into five groups based on the degree of obesity by BROCA method ; normal weight, overweight, and obesity which was further divided into three groups of light, moderate, and sever obesity. Various anthropomnetric measurements, overall eating habits, and dietery intakes were asessed for each groups. Out of eighteen anthropometric factors asociated with obesity, thirteen measurements were represented to be valid for the diagnosis of obesity. Body fat % which was analyzed by Bioelectrical Impedance fatnee Analyzer were 24.765, 28.05%, and 29.85 for normal, overweight, and obesity group respectively. WHR(waister to hip ratio) or BMI(body mass index) widely used index was also resulted to be valid as a predictor of obesity. Waist circumference which represents abdominal fat mass showed a good correlatin with body fat%. The analysis of dietary intakes suggested that the overintakes of total calorie may not be the only causal factor of obesity, rather the amount of daily protein, fat and carbohydrate intakes or the physical activity level would be more closely related with the prevalence of obesity. Further investigation considering more variety of food composition of diet and the activity level involving larger number of subjects would be needed.

• Preventive Nutrition and Food Science
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• v.15 no.4
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• pp.262-266
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• 2010

This study was performed to investigate the anti-obesity effect of Eisenia bicyclis in mice fed a high-fat diet (HFD). Male C57BL/6J mice were divided into three groups that were fed a normal diet, an HFD, or an HFD supplemented with a 5% powder of Eisenia bicyclis (PEB) for 8 weeks. The PEB group showed lower body weight gains than the HFD group. The PEB group also exhibited reduced body fat mass and adipose cell size in epididymal adipose tissue. The concentrations of serum cholesterol, leptin, and insulin in the PEB group were significantly lower than those in the HFD group. Liver triglyceride content was significantly decreased by PEB supplementation. Furthermore, hematoxylin and eosin staining revealed that PEB supplementation reduced lipid droplet formation in the liver induced by HFD. These results suggest that PEB supplementation reduces body weight gain and fat accumulation in HFD-induced obese mice.

• Korean Journal of Exercise Nutrition
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• v.17 no.2
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• pp.43-48
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• 2013

This study aims to investigate changes in plasma lipid concentrations and appetite-regulating hormone levels after a 4% body fat reduction using a 9-week intervention involving aerobic exercise, a fat-oxidizing agent, and diet limitation. After the 9-week intervention, the aerobic exercise plus hydroxycitric acid (EX+HCA), exercise (EX), and diet limitation (DIET) groups achieved the target 4% body fat reduction from the baseline value. None of the plasma lipid indicators showed significant intergroup differences, indicating that plasma lipid levels are not influenced by body weight regulation. With regard to appetite-regulating hormones, no significant intergroup differences were observed in glucose, insulin, or glucagon-like peptide-1 levels, unlike ghrelin and leptin. Ghrelin levels in particular tended to decrease in the DIET group and increase in the HCA+EX and EX groups. Leptin levels significantly decreased in the HCA+EX and EX groups, whereas no differences were observed in the DIET group. Such results indicate that exercise alone without the administration of obesity diet supplements induces elevation in ghrelin levels and reduction in leptin levels, but that diet restriction alone does not influence changes in leptin levels. Taken together, we could not confirm any synergic effects arising from the use of a fat-oxidizing agent during an exercise program to control body weight. Furthermore, diet limitation unsupported by exercise had no effect on muscle mass reduction or appetite-regulating hormone levels; thus, it is not recommended as an effective body weight control method.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.7
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• pp.995-1002
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• 2000

To evaluate energy efficiency and partition of nutrients, 32 piglets were weaned at 14 d of age and individually fed diets containing 15% fat from coconut oil (CO, medium chain saturated), high oleate sunflower oil (HOSO, n-9 series), soybean oil (SO, n-6 series), or linseed oil plus fish oil, (LF, n-3 series). After 4 weeks, the subjects were sacrificed to evaluate empty body composition and apparent ileal digestibility with the slaughter method. No statistical effect of dietary fat sources on growth was observed. The digestibility of fat from the coconut oil diet was higher than fats from the diets containing high levels of unsaturated fatty acids. The efficiency of use of metabolizable energy for growth averaged 63% and was not affected by the diet. Dietary fat composition was reflected strongly in backfat. Total body neutral and polar fatty acids were influenced too. For the whole body phospholipid fraction the ratio of n-6 to n-3 and the double bond index were 4.3, 5.8, 7.2, 0.78 and 69, 87, 89, 87 for CO, HOSO, SO, and LF respectively. These results show that for the coconut oil diet the degree of unsaturation of phospholipids in the body was lower and that, in the other diets, it did not differ, but double bond index was maintained with different n-6 to n-3 ratios in carcass fat. On the whole the data on body fat composition indicate that the dietary fat tended to be deposited in similar quantity in the body, whatever was the dietary fatty acid profile.

• Journal of the East Asian Society of Dietary Life
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• v.22 no.2
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• pp.231-238
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• 2012

$Dioscorea$ $batatas$ Decne is a type of yam that eaten raw and used as a traditional oriental medicine in Asian countries. In this study, we evaluated the functional effects of yam water extracts on body weight levels and serum lipid concentrations in mice fed high fat diet. Mice were divided into four groups: normal diet control (ND), high fat diet control (HFD), HFD+yam extract 100 mg/kg (HFD-Y100), and HFD+yam extract 200 mg/kg (HFD-Y200). Yam extract was administrated orally to mice fed a high fat diet for 5 weeks. Treatment with yam extract significantly reduced body weight levels and energy efficiency in a dose-dependent manner in HFD-fed mice. Yam extract also attenuated serum levels of triglyceride, total cholesterol, and LDL-cholesterol, as well as organ weights of liver and abdominal adipose tissue in mice fed a high fat diet. Moreover, blood levels of glucose, insulin, and leptin significantly decreased in a dose-dependent manner upon administration of yam extract. Blood activities of GPT, GOT, and LDH were lower in the yam extract-treated groups compared to the HFD group. These results indicate that yam water extract may reduce elevated body weight and serum lipid concentrations in mice fed a high fat diet, suggesting its usefulness as a functional food for reducing body fat and hyperlipidemia.

• The Korean Journal of Food And Nutrition
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• v.30 no.5
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• pp.900-907
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• 2017

This study was performed to investigate the body fat-lowering effect of garlic powder in peroxisome proliferator-activated receptor ${\gamma}$ coactivator-$1{\alpha}$(PGC-$1{\alpha}$)-luciferase transgenic mice (TG). In this study, we generated transgenic mice with a PGC-$1{\alpha}$ promoter (-970/+412 bp) containing luciferase as a reporter gene. Mice were fed a 45% high-fat diet for 8 weeks to induce obesity. Subsequently, mice were maintained on either a high-fat control diet (CON), or high-fat diets supplemented with 2% (GP2) or 5% (GP5) garlic powder for an additional 8 weeks. Dietary garlic powder reduced the body weight in the GP2 and GP5 groups, compared to the CON group. Furthermore, garlic supplementation significantly decreased the plasma levels of triglycerides, total cholesterol, and leptin in the GP5 group, compared to the CON group. Specifically, luciferase activity in liver, white adipose tissue (WAT), and brown adipose tissue (BAT) was increased by garlic supplementation in a dose-dependent manner. These results suggest that the body fat-lowering effect of garlic powder might be related to PGC-$1{\alpha}$ by the increase in luciferase activity in liver, WAT, and BAT. Furthermore, transgenic mice might be useful for evaluating the body fat-lowering effect of various health functional foods.

• Korean Journal of Community Nutrition
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• v.29 no.3
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• pp.189-198
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• 2024

Objectives: The sodium index is an index that converts the estimated sodium intake calculated using a verified and reliable sodium estimation formula. This study aimed to determine the relationship between the sodium index and obesity indicators and the potential impact of excessive sodium consumption on obesity. Methods: Obesity indicators, such as body mass index (BMI), body fat percentage, waist-to-hip ratio (WHR), and visceral fat levels, were analyzed in 120 university students (60 men and 60 women). The sodium index was calculated by indexing the estimated sodium intake according to age, sex, BMI, salt-eating habits, and salt-eating behaviors. The relationship between sodium index and obesity indicators was analyzed using multiple logistic regression. Results: The estimated sodium intake was 3,907.1 mg, with 76.7% of the participants categorized under the "careful" level of sodium index and 10.8% under the "moderate" level. As the sodium index increased, the BMI, body fat percentage, WHR, and visceral fat levels significantly increased. All obesity indicators significantly increased in patients with a "severe" sodium index than in those with a "moderate" sodium index. In addition, a strong positive correlation was identified between obesity indicators and sodium index. When the "severe" sodium index was compared with the "moderate" sodium index, the risk of obesity based on body fat percentage increased by 2.181 times (95% confidence interval [CI], 1.526-3.118), while the risk of obesity based on visceral fat level increased by 4.073 times (95% CI, 2.097-7.911). Conclusions: Our findings suggest a correlation between excessive sodium intake and obesity. Moreover, the sodium index can be used to determine sodium intake.

• Nutritional Sciences
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• v.6 no.1
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• pp.42-47
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• 2003

The objective of this study was to examine how circulating leptin concentrations and resting energy expenditures (REE) are related to body composition in obese adults, and to examine differences in these parameters according to gender. Twenty-three subjects, 6 males and 17 females, were recruited from patients with a body mass index (BMI) of greater than 27 at the Obesity Clinic of the K University Hospital. Anthropometric assessments and biochemical analyses were performed, and REEs were measured. In spite of having similar BMI values the plasma leptin levels of females (20.0$\pm$6.5 ng/ml) were significantly higher (p<.05) than those of males (14.2$\pm$6.1) ng/ml). In females, plasma leptin concentrations were found to be positively related to body weight. BMI, waist-hip ratio (WHR), fat mass (FM), body fat, and to the circumferences of forearm, waist and hip (p<.0001). However, in males, plasma leptin concentrations were positively related only to suprailiac thickness (p<.05). The higher plasma leptin levels in females compared to males may, at least partially. be explained by the females' higher subcutaneous fat mass. Plasma leptin concentrations appeared to reflect not only total fat mass but also regional fat distribution, especially in females. REE values of males (2254.3$\pm$256.2 kcal/day) were significantly higher (p＜.01) than those of females (1799.1$\pm$454.7 kcal/day). REE values for females were positively related to body weight, BMI, lean body mass (LBM), FM, body fat, and to the circumferences of waist and hip (p<.05); however, REE values for males were (positively) related only to LBM (p<.05). REE values were not related to plasma leptin concentrations for either males or females, indicating that the plasma level of leptin might not be a predictor for REE value.

• Korean Journal of Community Nutrition
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• v.2 no.3
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• pp.319-326
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• 1997

This study was to investigate the level of serum lipids and obesity in housewives in Mooan, and relationships between them. The average age, height and weight were 51.1 years, 154.3cm and 58.3kg respectively. The level of obesity of subjects was higher than that of housewives in other areas investigated in other studies. BMI and RBW underestimated in the obese compared to BIA. The amounts of lean body mass and total body water of subjects above 60 years old were smaller than those of forties and their BMI and RBW were lower than those of forties. However, their body fat percentage was nearly same as that of forties. Serum HDL-cholesterol(HDL-C) of subjects was lower than 55mg/㎗, the lower limit of normal range. Triglyceride of subjects above 60years old was higher than the 95th percentile of those of the same age with reference to Mayo clinic. The serum total cholesterol(TC) showed positive correlation with LDL-cholesterol(LDL-C) and TC/HDL-C(p<0.001). LDL-C showed positive correlation with TC(p<0.001), but negative correlation with HDL-C(p<0.05). HDL-C showed negative correlation with triglyceride(p<0.05). TC/HDL-C showed a positive correlation with triglyceride(p<0.05). HDL-C was the serum lipid which showed the highest correlation with obesity and body composition. It showed a negative correlation with the percentage of body fat(p<0.001), total body fat(p<0.001), BMI(p< 0.05) and RBW(p<0.05). TC/HDL-C showed positive correlation with the percentage of body fat(p<0.01) and total body fat(p<0.05). As the result of above, it is needed to make more researches to find out the proper method to estimate the obesity of subjects and educate subjects in Mooan about nutritional information for obesity.

• Journal of Korean Biological Nursing Science
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• v.13 no.3
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• pp.276-282
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• 2011

Purpose: The aim of the present study was to investigate the effects of a aquatic exercise program on body mass index, body fat percentage and skeletal muscle mass, physical fitness using SFT (senior fitness test) and depression in elderly women. Methods: This study included 59 elderly women. Aquatics exercise program was performed three times per week for 12 weeks using rating of perceived exertion and body mass index, body fat percentage, skeletal muscle mass, physical fitness and depression were measured before and after exercise program. Statistical analysis was performed using t-test. Results: Body mass index (p=.002) and body fat percentage (p=.021) were significantly decreased after aquatic exercise program. Chair stand (p=.009), 2 minute step test (p<.001), back scratch (p<.001), and chair sit and reach (p<.001) were significantly increased after the aquatic exercise program. But, there was no significant differences in the depression. Conclusion: It is suggested the aquatic exercise program may play a significant role in improving body fat and physical fitness in the elderly women. However, as well as aquatic exercise program, sustained encouragement are required to improve physical and psychological traits.