• The Korean Journal of Physiology and Pharmacology
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• v.2 no.1
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• pp.95-100
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• 1998

The conductance change evoked by step depolarization was studied in primarily cultured rat adrenal chromaffin cells using patch-clamp and capacitance measurement techniques. When we applied a depolarizing pulse to a chromaffin cell, the inward calcium current was followed by an outward current and depolarization-induced exocytosis was accompanied by an increase in conductance trace. The slow inward tail current which has the same time course as the conductance change was observed in current recording. The activation of slow tail current was calcium-dependent. Reversal potentials agreed with Nernst equation assuming relative permeability of $Cs^+\;to\;K^+$ is 0.095. The outward current and tail current were blocked by apamin (200 nM) and d-tubocurarine (2 mM). The conductance change was blocked by apamin and did not affect membrane capacitance recording. We confirmed that conductance change after depolarization comes from the activation of the SK channel and can be blocked by application of the SK channel blockers. Consequently, it is necessary to consider blocking of the SK channel during membrane capacitance recording.

• Biomedical Science Letters
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• v.15 no.4
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• pp.287-293
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• 2009

Phospholipase D (PLD) is an enzyme hydrolyzing phosphatidylcholine to phosphatidic acid (PA) and choline. We investigated the involvement of PLD1 in the uptake of norepinephrine (NE) in PC12 cells, pheochromocytoma cells. NE uptake was specific in PC12 cells because nomifensine, a specific blocker of NE transporter, blocked NE uptake. Inhibition of PLD function in PC12 cells by the treatment of butanol suppressed the NE uptake. In contrast, overexpression of PLD1 in PC12 cells increased NE uptake efficiently. These results suggest that PLD activity is involved in NE uptake. We explored the action mechanism of PLD in NE uptake. PA phosphatase inhibitor, propranolol, blocks the formation of PKC activator diacylglycerol from PA. Propranolol treatment to PC12 cells blocked dramatically the uptake of NE. Specific PKC inhibitors, GF109203X and Ro31-8220, blocked NE uptake. Taken together, we suggest for the first time that PLD1 activity is involved in NE uptake via the activation of PKC.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.15 no.9 s.102
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• pp.1077-1083
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• 2005

Electro-Active Paper (EAPap) is one of attractive electro-active polymer (EAP) materials for artificial muscles due to its many advantages such as light weight, biologically degradable, low cost, large displacement output, low actuation voltage and low power consumption. However, drawbacks of EAPap actuators include low force output and humidity dependence. To enhance the performance of EAPap, conductive polymer (PPy) and SWNT/conductive polymer (PANI) are coated on EAPap PPy as conductive polymer is coated on cellulose EAPap by means of electrochemical deposition. Two different dopants are used in PPy through conducting polymer processing. SWNTS are mixed with PANI in emeraldine base along with different dopants. The compound materials are coated on cellulose EAPap using spin coating system. The performance of PPy/EAPap and SWNT/PANI/EAPap are evaluated in terms of bending displacement, blocked force, and the effects of dopants, humidity, coaling time, voltage and frequency are investigated. Comparing with EAPap actuators, SWNT/PANI/EAPap actuators show $200\%$ improvement of bending displacement and $300\%$ increment of blocked force.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.7 no.8
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• pp.1674-1683
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• 2003

The performance of a packet data multiplexer with stop­and­wait ARQ protocols under Markovian interruption is considered in this work It is assumed that the input process, into the system is Poisson process, and that the output channel is divided into a series of time slots and a data packet can be transmitted in a slot time. In this system the round­trip propagation delay is defined to be the frame time. It is modeled that the output channel can be blocked by some Markevian interruption, whose state change between the blocking and non­-blocking states is given by Markov process. The overall system has been analyzed by constructing a relationship, taking the Markovian interruption into account, about the buffer behavior between the successive frames of slots. The validity of this analytical results has been verified by computer simulation.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.8
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• pp.1183-1196
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• 2018

Objective: This study ascertained effects of roughage quality, period of day at meal termination and time lapse after feeding on digesta load in the rumen. Methods: Veld hay was untreated (poor roughage quality, PRQ), improved (improved roughage quality, IRQ) by treating with urea or semi-improved by spraying with urea (semi-improved roughage quality, SIRQ). Experiment 1a used four rumen fistulated sheep to determine in-sacco degradability. Twelve sheep ($56.3{\pm}4.59kg$) were blocked by weight and randomly allocated to IRQ (n = 6) and PRQ (n = 6) to determine solid and liquid passage rates. In experiment 1b, nine sheep ($37.6{\pm}9.34kg$) were blocked by weight and randomly allocated to IRQ (n = 4) and PRQ (n = 5) to determine digestibility. Sixteen sheep ($36.47{\pm}9.46kg$) were blocked by body weight and randomly allocated to IRQ (n = 8) and PRQ (n = 8). Two sheep were slaughtered for each sampling time in each treatment (IRQ and PRQ) at 0, 6, 12, and 24 h after feeding to determine rumen load. In experiment 2, eighteen goats ($25.4{\pm}9.08kg$) were blocked by weight and randomly allocated to IRQ (n = 6), SIRQ (n = 6), and PRQ (n = 6). Then all 18 goats were slaughtered soon after meal termination in the morning; afternoon and evening to determine the effect of period of day on rumen fill. Results: Rate of degradation and effective degradability were enhanced by improvement of roughage quality. Roughage quality had no effect on digestibility, but digestibility was higher in goats than sheep. Fractional passage rate of particles was higher for IRQ than PRQ, but similar for liquids. Digesta fractional clearance rates at 24 h after feeding were 0.018/h (IRQ) and 0.006/h (PRQ). Period of day had an influence on rumen load. Neutral detergent fibre load for goats were above 2.03 kg/100 kg body weight for all diet treatments. Conclusion: Following starvation, passage rate had negligible effects on emptying of rumen load.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.24 no.12
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• pp.47-56
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• 2010

For a human being's smooth activity, the clean air and comfortable lighting environment are needed. The suitable lighting environment is obtained generally by making it available for being formed the bright situation easy for seeing object and the visually comfortable atmosphere. In this way, even the lighting environment was changed along with economic development. Even a light source was diversified. Thus, several kinds of new light sources such as LED, OLED, PLS, and CNT came to appear. Halogen lamp, which has low efficiency due to high color rendering among lamps of being used now, is being much used yet. However, owing to radiation of UV and IR, there are many limitations to the subject in general exhibition lighting, museum, and art museum. Accordingly, a research was performed on filter that is blocked UV and IR at the same time, by using halogen lamp that is excellent in color rendering and in life.

• Journal of Broadcast Engineering
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• v.15 no.3
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• pp.407-413
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• 2010

In DCA (Dynamic Channel Allocation) scheme of uplink cellular system appling a frequency reuse factor of one, when a new call requests a channel, the new call will be blocked if its SINR (Carrier to Noise and Interference Ratio) is less than the required SINR or there is no available channel. The additional channel allocation for the blocked new call can be performed with channel borrowing in the adjacent cells. The channel borrowing causes the CCI (Co-Channel Interference), thus the SINR of the existing calls is deteriorated and the channel reallocation for the existing calls is required. As a result, the channel borrowing leads to a complex calculation so that it is a NP-hard problem. Therefore, to overcome the problem, we propose a novel Group Search-based DCA scheme which decreases the number of the blocked new calls and then reduces the number of the channel reallocation by the channel borrowing for the blocked new calls. The proposed scheme searches the all channels in a group of the adjacent cells and home cell at the same time in order to minimizes the number of the blocked new calls. The simulation results show that proposed Group Search-based DCA scheme provides better new call blocking probability and system throughput than the existing Single Search-based DCA scheme which searches only the channels in home cell.

• International Journal of Highway Engineering
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• v.18 no.1
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• pp.119-129
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• 2016

PURPOSES : The purpose of this study is to develop a methodology for estimating additional carbon emissions due to freeway incidents. METHODS : As our country grows, our highway policy has mainly neglected the environmental and social sectors. However, with the formation of a national green growth keynote and an increase in the number of people interested in environmental and social issues, problems related to social issues, such as traffic accidents and congestion, and environmental issues, such as the impact of air pollution caused by exhaust gases that are emitted from highway vehicles, are beginning to be discussed. Accordingly, studies have been conducted on a variety of environmental aspects in the field of road transport, and for the quantitative calculation of greenhouse gas emissions, using various methods. However, in order to observe the effects of carbon emissions, microscopic simulations must use many difficult variables such as cost, analysis time, and ease of analysis process. In this study, additional greenhouse gas emissions that occur because of highway traffic accidents were classified by type (incident handling time, number of lanes blocked, freeway level of service), and the annual additional emissions based on incidents were calculated. According to the results, congestion length and emissions tend to increase with an increase in incident clearance time, number of occupied lanes, and worsening level of service. Using this data, we analyzed accident data on the Gyeong-bu Expressway (Yang-Jae IC - Osan IC) for a year. RESULTS : Additional greenhouse gas emissions that occur because of highway traffic accidents were classified by type (incident handling time, number of lanes blocked, freeway level of service) and annual additional emissions caused by accidents were calculated. CONCLUSIONS : In this study, a methodology for estimating carbon emissions due to freeway incidents was developed that incorporates macroscopic flow models. The results of the study are organized in the form of a look-Up table that calculates carbon emissions rather easily.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.19 no.4
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• pp.443-457
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• 2015

We consider the M/M/c/c queues in which the customers blocked to enter the service facility retry after a random amount of time and some of idle servers can leave the vacation. The vacation time and retrial time are assumed to be of phase type distribution. Approximation formulae for the distribution of the number of customers in service facility and the mean number of customers in orbit are presented. We provide an approximation for M/M/c/c queue with general retrial time and general vacation time by approximating the general distribution with phase type distribution. Some numerical results are presented.

• Journal of KIISE:Computer Systems and Theory
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• v.33 no.6
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• pp.337-343
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• 2006

The Stack Resource Policy (SRP) is a real-time synchronization protocol with some distinct properties. One of such properties is early blocking; the execution of a job is delayed instead of being blocked when requesting shared resources. If SRP is used with dynamic priority scheduling such as Earliest Deadline First (EDF), the early blocking requires that a scheduler should select the highest-priority job among the jobs that will not be blocked, incurring runtime overhead. In this paper, we analyze the runtime overhead of EDF scheduling when SRP is used. We find out that the overhead of job search using the conventional implementations of ready queue and job search algorithms becomes serious as the number of jobs increases. To solve this problem, we propose an alternative data structure for the ready queue and an efficient job-search algorithm with O([log$_2n$]) time complexity.