• Fisheries and Aquatic Sciences
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• v.20 no.11
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• pp.28.1-28.17
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• 2017

Members of the phylum Echinodermata, commonly known as echinoderms, are exclusively marine invertebrates. Among the Echinodermata, sea cucumber belongs to the family Holothuroidea. The sea cucumber Stichopus (Apostichous) japonicus (Selenka) is an invertebrate animal inhabiting the coastal sea around Korean, Japan, China, and Russia. Sea cucumber has a significant commercial value, because it contains valuable nutrients such as vitamins and minerals. They possess a number of distinctive biologically and pharmacologically important compounds. In particular, the body wall of sea cucumber is a major edible part. It consists of peptide, collagen, gelatin, polysaccharide, and saponin, which possess several biological activities such as anti-cancer, anti-coagulation, anti-oxidation, and anti-osteoclastogenesis. Furthermore, the regenerative capacity of sea cucumber makes it a medically important organism. This review presents the various biological activities and biomedical potential of sea cucumber S. japonicus.

• Korean Chemical Engineering Research
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• v.44 no.3
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• pp.270-276
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• 2006

In this study, heat loss through free surface of water contained in bathtub due to conduction and evaporation has been analyzed. As a result of this study, a relational equation has been derived based on the basic theory of heat transfer to evaluate the performance of bath tubes. The derived equation was rational and quantitative. The major heat loss was found to be due to evaporation. Moreover, it has been found out that the speed of heat loss depends more on the humidity of the bathroom than the temperature of water contained in the bathtub. So, it is best to maintain the temperature of bathtub water to be between 41 to $45^{\circ}C$ and the humidity of bathroom to be 95％.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.834-837
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• 2005

In this paper, we describe the method of non-invasive blood pressure measurement using pulse wave transit time(PWTT). PWTT is a new parameter involved with a vascular that can indicate the change of BP. PWTT is measured by continuous monitoring of ECG and pulse wave. No additional sensors or modules are required. In many cases, the change of PWTT correlates with the change of BP. We measure pulse wave using the photo plethysmograph(PPG) sensor in an earlobe and we measure ECG using the ECG monitoring device our made in the chest. The measurement device for detecting pulse wave consists of infrared LED for transmitted light illumination, pin photodiode as light detector, amplifier and filter. We composed 0.5Hz high pass, 60Hz notch and 10Hz low pass filter. ECG measurement device consists of multiplexer, amplifier, filter, micro-controller and RF module. After amplification and filtering, ECG signal and pulse wave is fed through micro-controller. We performed the initial work towards the development of ambulatory BP monitoring system using PWTT. An earlobe is suitable place to measure PPG signal without the restraint in daily work. From the results, we can know that the dependence of PWTT on BP is almost linear and it is possible to monitoring an individual BP continuously after the individual calibration.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.49 no.2
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• pp.124-130
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• 2016

To effectively remove salts from Suaeda japonica, extracts, an electrodialysis system was developed. The biological activities of non-desalted (NDS) and desalted S. japonica (DS) extracts were compared. The DS extract exhibited superior polyphenolic (6.26%) and carbohydrate (28.56%) contents. The IC₅₀ values of the DS extract against DPPH radicals and hydrogen peroxide were 0.22 and 0.68 mg/mL, respectively, which was higher than that of the NDS extract. Neither the DS nor the NDS extract was cytotoxic in RAW 264.7 macrophages. Additionally, the DS extract had a higher NO inhibitory effect compared to the NDS extract in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages. These data indicate that DS extracts have greater biological activity than do ND extracts, and application of the electrodialysis process may be useful in marine bioresource applications.

• Korean Institute of Interior Design Journal
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• v.20 no.5
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• pp.68-77
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• 2011

In this research it is concentrated first of all on the attempts to reconstruct the historical context of the idea for the space design based on the natural construction and to re-appropriate il critically to the present context. Sequentially in the areas of philosophy, biology, neuroscience, and architecture it has been variously discussed on the problems about the synthesis of biology and techniques. In the context of the consilience of biology and technique Werner Nachtigall, who has intended to shed light on the morphological principles in the natural construction, founded the 'Bionik', which is different from the bionics or the biomechanics that are oriented to the imitation of natural forms. The space design that is on the basis of the Bionik treats organisms as a functional whole. Therefore the Bionik space design follows two kinds of principle such as the principle of analogy and the principle of optimization. After all the understanding of the consilience of nature and technique for Nachtigall and Bionik designers tends toward the explication of the complex process in which the human perceptions, the environment, and the phenomenal techniques are united together, and this complex process is associated with the space design based on the Bionik.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.53 no.5
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• pp.688-693
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• 2020

Vibrio vulnificus is a Gram-negative marine bacterium known to cause septicemia. This study was conducted to investigate the distribution of V. vulnificus along the coast of Gadeok Island in Korea and to determine the molecular characteristics of isolated strains sampled between March and November 2019 from seawater. The strains were mostly detected between July and September, when the average water temperature and average salinity were 22.2-26.2℃ and 14.2-29.9 psu, respectively. V. vulnificus was not detected in seawater below 15℃. In September, the highest population of V. vulnificus was observed at 2,100 MPN (most probable number)/100 mL, attributable to decreased salinity from heavy rains. In addition, the detection rate of V. vulnificus was higher at the sampling station near the Nakdong River. Virulence-related genes were also identified among the isolates, such as vvhA (97.1%), viuB (44.1%), and vcgC (57.4%). In particular, viuB and vcgC were only observed in V. vulnificus isolated from June to September, when the detection rate was high and water temperature was above 20℃, suggesting the role of seasonal characteristics.

• Proceedings of the Korea Information Processing Society Conference
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• 2005.11a
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• pp.1141-1144
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• 2005

본 논문은 실내에서 홈 거주자의 위치를 인식하기 위해 근접성을 이용한 위치 추적 시스템 환경을 제안하고자 한다. 이를 위해 기존 실내의 고정된 위치에 있는 구조/시설물 및 가전제품의 ON/OFF 스위치를 이용하며 기타 추가적인 스위치 및 센서를 부착하여 개폐동작이 일어날 때 발생되는 신호를 검출하여 실제위치를 얻는다. 발생되는 신호는 Pull-up 저항을 이용한 신호 검출 방법으로 눌려진 스위치나 센서에서 발생된 아날로그 신호를 검출한다. 검출된 신호의 고유한 ID값은 Sensor TMO로 송신되어 수집된다. 수집된 센서ID는 소켓통신을 이용하여 홈서버인 실내위치추적시스템으로 보내질 뿐아니라 원격 모니터링 GUI를 통해 실내 거주자의 위치를 GUI의 가상공간 좌표와 매핑된 홈 거주자의 위치를 보인다. 본 논문에서 제안한 실내위치추적시스템은 홈 거주자의 위치를 주기적으로 모니터링하고 거주자의 이동 패턴과 활동 상황을 파악하여 헬스케어 정보로 활용할 예정이다.

• Journal of Biomedical Engineering Research
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• v.26 no.3
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• pp.177-184
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• 2005

In this paper, we proposed a new hearing aid algorithm to improve SNR(signal to noise ratio) of noisy speech signal and speech perception. The proposed hearing aid algorithm is a multi-band loudness compensation based independent component analysis (ICA). The proposed algorithm was compared with a conventional spectral subtraction algorithm on behind-the-ear type hearing aid. The proposed algorithm successfully separated a target speech signal from background noise and from a mixture of the speech signals. The algorithms were compared each other by means of SNR. The average improvement of SNR by ICA based algorithm was 16.64dB, whereas spectral subtraction algorithm was 8.67dB. From the clinical tests, we concluded that our proposed algorithm would help hearing aid user to hear clearly a target speech in noisy conditions.

• Journal of Biomedical Engineering Research
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• v.19 no.3
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• pp.285-290
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• 1998

There are various reports on the fracture of mechanical heart valves implanted in human or animal, and they are pointed out that problems are induced by an erosion of disk surface, due to a cavitation effect. We have been investigating this mechanism using accelerated fatigue tester, and it was found that erosion was enhanced by a compliance effect in the test circuit. In this study, effects of compliance value and location on erosion were discussed, while disk closing velocity was measured by a high speed video camera. It was clarified that faster closing velocity was resulting in a enhancement of erosion on the disk surface.

• International Journal of CAD/CAM
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• v.11 no.1
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• pp.18-26
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• 2011

This paper proposes a new solid-shape modeling system based on a lusterware-image illustration. The proposed method reconstructs a three dimensional solid shape from a set of rough sketches that are typically drawn in the early stages of the design process. The sketches do not have to be strictly accurate, and this tolerance to the roughness of the input sketches is one of the major advantages of the proposed method. The proposed system creates an initial shape based on the silhouette of the input lusterware-images. Then the user can edit the initial shape with intuitive cutting and dishing-up operations, which are based on sketching user interface. To achieve the goal, the system retains the geometric model with two representations: a point-set data and a volume data. This dual data structure allows the program to create an initial shape from the input images with little computational cost, and the user can apply cutting and dishing-up operations without substantially increasing computational and memory requirements. In this research, we have tested the proposed system by reconstructing solid models of some mechanical parts from rough sketches. The experimental results indicate that the proposed method is useful for the prototyping of a solid shape.