• Title/Summary/Keyword: biomedical

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A Functional Mapping Workstation of Human Brain Images

  • Paik, Chul-Hwa;Kim, Tae-Woo;Song, Myung-Jin;Yu, Hyun-Sun;Kim, Won-Ky
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.301-303
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    • 1996
  • A platform is developed for fast and effective functional mapping of human brain, which can allow semi-automatically the whole processes of an image segmentation, a fusion of MR and PET images, and 3-D rendering of volumetric data, including DICOM-based image transfers from PACS archiver within a short period of time.

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Activation of Limbic Area due to Oxygen Administration during Visuospatial Task (공간 과제 수행 시 고농도 산소 공급에 의한 변연계 활성화에 관한 연구)

  • Choi, Mi-Hyun;Lee, Su-Jeong;Yang, Jae-Woong;Kim, Ji-Hye;Choi, Jin-Seung;Tack, Gye-Rae;Chung, Soon-Cheol;Kim, Hyun-Jun
    • Science of Emotion and Sensibility
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    • v.12 no.4
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    • pp.443-450
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    • 2009
  • The purpose of this study is to observe activation of limbic system during performing visuospatial tasks by 21% and 30% oxygen administration. Eight right handed male college students were selected as the subjects for this study. A visuospatial task was presented while brain images were scanned by a 3T fMRI system. The experiment consisted of two runs: one was a visuospatial task under normal air(21% oxygen) condition and the other under hyperoxic air(30% oxygen) condition. The neural activations were observed at the limbic system which is seperated 8 regions such as cingulate gyrus, thalamus, limbic lobe, hypothalamus, hippocampus, parahippocampa gyrus, amygdala, and mammiilary body. By two oxygen levels, activation areas of limbic system are almost identical. Increased neural activations were observed in the cingulate gyrus and thalamus with 30% oxygen administration compared to 21% oxygen. During 30% oxygen administration, improvement of visuospatial task performance has a relation to increase of neural activation of subcortical structures such as thalamus and cingulate gyrus as well as cerebral cortex.

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Gender Differences of Heart Rate due to Change of Supply Rate of Highly Concentrated Oxygen (고농도 산소 공급량 변화에 따른 심박동율의 성별 차이)

  • Choi, Mi-Hyun;Kim, Ji-Hye;Lee, Su-Jeong;Yang, Jae-Woong;Choi, Jin-Seung;Tack, Gye-Rae;Lee, Tae-Soo;Min, Byung-Chan;Chung, Soon-Cheol
    • Journal of the Ergonomics Society of Korea
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    • v.29 no.2
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    • pp.197-202
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    • 2010
  • The purpose of this study was to examine differences between male and female in heart rate due to 93% oxygen administration of the three levels (1L/min, 3L/min, and 5L/min). Ten healthy male (25.0$\pm$1.8years) and ten female (23.7$\pm$1.9years) college students were selected as the subjects for this study. The experiment consisted of three runs, i.e., the three levels of 93% oxygen administration, respectively. The each run consisted of three phases, i.e., Rest 1 (5min), Hyperoxia (10min), and Rest 2 (5min). Heart rate was measured throughout the three phases. Heart rate was decreased during hyperoxia compared to Rest 1 and 2. By increasing the supply rate of highly concentrated oxygen, ${\Delta}1$ (decreasing rate of heart rate during hyperoxia compared to Rest 1) was increased. And ${\Delta}2$ (decreasing rate of heart rate during hyperoxia compared to Rest 2) of male was lower than female, regardless of supply rate.

Anti-melanogenesis Effect of Ganoderma lucidum Mycelial Extract Supplemented with Oriental Raisin Tree (Hovenia dulcis) Extract (헛개나무 추출물이 첨가된 영지버섯균사 추출물의 멜라닌 생성 억제효과)

  • Kim, Hong Il;Jeong, Yong Un;Kim, Jong Hyun;Choi, In Ho;Lee, Jun Ho;Lee, Chang Soo;Park, Young Jin
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.43 no.4
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    • pp.357-364
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    • 2017
  • The aim of this study is to investigate the effect of Hovenia dulcis (oriental raisin tree) extract on ganodermanondiol (GN) contents in Ganoderma lucidum (G. lucidum) mycelia. GN has a triterpenoid structure and is one of the major active components of G. lucidum. Furthermore, we previously proved its inhibitory effects on tyrosinase activity and melanin biosynthesis in B16F10 melanoma cells. In this study, we observed significantly increased GN contents in G. lucidum mycelial extracts supplemented with 15% (v/v) oriental raisin tree extract (ORTE) by HPLC analysis. In addition, melanogenesis was significantly inhibited by G. lucidum extract supplemented with 15% ORTE when compared to G. lucidum extract without ORTE supplementation. Furthermore, mycelial growth of G. lucidum was increased by ORTE supplementation in both solid and liquid cultivation. These results suggest that the oriental raisin tree is useful as natural ingredient for increasing GN biosynthesis as well as whitening effect of G. lucidum.