• Proceedings of the KOSOMBE Conference
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• v.1994 no.05
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• pp.53-56
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• 1994

We have developed biological signal measurement modules and data acquisition and control card for a biological signal measurement, archiving, and communication system (SiMACS). Biological signals included in this system are ECG, EEG, EMG, invasive blood pressure, respiration, and temperature. Parameters of each module can be controlled by PC-base IDPU (intelligent data processing unit) through a data acquisition and control card. The data acquisition and control card can collect up to 16 channels of biological signals with sampling rate of $50\;{\sim}\;2,000Hz$ and 12-bit resolution. All measurement moduls and data acquisition functions are controlled by microcontroller which receives commands from PC. All data transfers among PC, microcontroller, and ADC are done through a shared RAM access by polling method for real rime operation.

• Journal of Biomedical Engineering Research
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• v.29 no.4
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• pp.295-301
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• 2008

A wireless 3 channel ECG monitoring system was developed so that it could monitor the health and movement state during subject's daily life. The developed system consists of a wireless biomedical signal acquisition device, a personal healthcare server, and a remote medical server. Three experiments were performed to evaluate the accuracy, reliability and operability, applicability during daily life of the developed device. First, ECG signals were measured using the developed device and commercial reference device during sitting and marking time and compared to verify the accuracy of R-R intervals. Second, the reliable data transmission to remote server was verified on two types of simulated emergency event using patient simulator. Third, during five types of motion in daily life, the accuracy of data transmission to remote server using CDMA network was verified on two types of event occurring. By acquiring and comparing subject's biomedical signal and motion signal, the accuracy, reliability and operability, applicability during daily life of the developed device were verified. In addition, PDA-phone based wireless system enabled subject to be monitored without any constraints. Therefore, the developed system is expected to be applicable for monitoring the aged and chronic diseased people and giving first-aid in emergency.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.222-226
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• 1995

인공심장에서의 박출량제어는 전부하에 따른 심박출균형, 심실내 완전충만과 완전구출을 구현하는데 그 목적이 있다. 본 논문에서는 인공심장 내부의 심실간 공간 압력파형을 심박출량의 제어에 활용하였다. 이를 위해서는 심실간 공간의 압력파형을 심실 유입부와 유출부의 혈류량에 대한 정보, 이동작동기의 위치신호와 동기시켜 해석하는 것이 필요하다. 이러한 압력파형의 해석을 바탕으로, 심실간 공간의 음압 크기로 좌,우 심방압을 추정하고 작동기의 좌,우 수축기때 심실간 공간의 음압크기를 비슷하게 유지하도록 작동거리를 제어하면 좌우 심박출 균형을 이룰 수 있음을 확인하였다. 또한, 심실의 완전충만과 완전구출의 실현을 위한 심실 충만 정도를 추정할 수 있게 하는 인자를 제시하였다.

• Fisheries and Aquatic Sciences
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• v.20 no.11
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• pp.28.1-28.17
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• 2017

Members of the phylum Echinodermata, commonly known as echinoderms, are exclusively marine invertebrates. Among the Echinodermata, sea cucumber belongs to the family Holothuroidea. The sea cucumber Stichopus (Apostichous) japonicus (Selenka) is an invertebrate animal inhabiting the coastal sea around Korean, Japan, China, and Russia. Sea cucumber has a significant commercial value, because it contains valuable nutrients such as vitamins and minerals. They possess a number of distinctive biologically and pharmacologically important compounds. In particular, the body wall of sea cucumber is a major edible part. It consists of peptide, collagen, gelatin, polysaccharide, and saponin, which possess several biological activities such as anti-cancer, anti-coagulation, anti-oxidation, and anti-osteoclastogenesis. Furthermore, the regenerative capacity of sea cucumber makes it a medically important organism. This review presents the various biological activities and biomedical potential of sea cucumber S. japonicus.

• Journal of Biomedical Engineering Research
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• v.27 no.6
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• pp.343-350
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• 2006

Medical magnetic stimulator generates strong magnetic field pulses. Clinical applications of the magnetic pulse are the stimulation of nervous system and the contraction of muscle. The unique source of the strong magnetic pulse is a capacitor-inductor resonator and this inductor generates a strong sinusoidal magnetic pulse by discharging the capacitor with high initial voltage. Continuous muscle contraction needs sequential generation of the magnetic pulses. However, to keep the magnitude of sequential pulses identical, an expensive high-voltage power supply have to support voltage drop of the capacitor between the pulses. A protection circuit between the supply and the resonator is necessary to protect the supply from reverse current caused by capacitor voltage reversal. In this paper, a new circuit structure of the magnetic stimulator adopting a low-frequency fly-back switching is proposed. The new circuit supports sequential pulse generation and allows the reverse current without damage. Performance of the new circuit is examined and a low-cost magnetic stimulator for urinary incontinence therapy is being developed using the presented method.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.55-58
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• 1997

In this paper we reviewed and stated the present state of our team's research of the moving-actuator type total artificial heart (MA-TAH). Especially, this paper showed new direction of researches. The integrated research of battery, telemetry, TET is required. And the real-time supervisory of the state of hemodynamic variables and MA-TAH is also needed. These requirement made us to think the supervisory control system (SCS). As functional abilities of the SCS require very high computational cost, the digital signal processor is an appropriate choice for our need.

• Journal of Biomedical Engineering Research
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• v.39 no.2
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• pp.63-68
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• 2018

In modern society, speech recognition technology is emerging as an important technology for identification in electronic commerce, forensics, law enforcement, and other systems. In this study, we aim to develop an age classification algorithm for extracting only MFCC(Mel Frequency Cepstral Coefficient) expressing the characteristics of speech in Korean and applying it to deep learning technology. The algorithm for extracting the 13th order MFCC from Korean data and constructing a data set, and using the artificial intelligence algorithm, deep artificial neural network, to classify males in their 20s, 30s, and 50s, and females in their 20s, 40s, and 50s. finally, our model confirmed the classification accuracy of 78.6% and 71.9% for males and females, respectively.

• Proceedings of the Korean Society of Computer Information Conference
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• 2013.07a
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• pp.359-360
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• 2013

본 연구에서는 외부 자극과 내적인 교감신경의 변화에 따라 나타나는 땀 반응으로 얻어진 생체신호를 다루었다. 즉, 땀 반응을 지칭하는 피부전도도를 측정할 수 있는 시스템과, 더불어 차량 운전시 혹은 운동 등의 동적 자극에 의한 영향을 최소화하여 교감신경에 의한 피부전도도의 신뢰도를 높일 수 있는 방안을 강구하였다. 기존의 두 개의 전극 간 리지스턴스(Resistance)를 측정하는 방식을 내부에서 분리된 한 개의 전극을 사용하여 신체적 움직임의 제한점을 해소하고 피부전도도로 나타난 생체신호가 외적인 움직임에 따른 영향인지 내적인 신경의 변화에 따른 영향인지를 추정할 수 있는 모듈을 개발하였다. 20명의 건강한 청년을 대상으로 피실험하여 기존의 생체신호 측정 장비인 MP-150의 EDA모듈과 동시 측정한 결과, 두 데이터가 약 88% 일치하는 것으로 확인하였다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2013.07a
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• pp.357-358
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• 2013

본 논문에서는 커패시턴스를 이용해 수액 내에 있는 공기방울을 검출하고 수액의 성분을 구분 할 수 있는 측정기의 원리에 대해 제시해보려 한다. 이 측정기의 원리는 유전율의 변화를 감지하여 수액의 종류를 판단하고, 수액 내부의 기포를 검출해내는 등 의원성 사고를 근본적으로 막는 데에 그 의의가 있다. 실험결과 본 연구에서 제작한 측정기로 수액에 따른 값의 차이를 확인하였고, 발생한 기포에 대한 출력 결과를 확인할 수 있었다. 본 연구를 통해 커패시턴스 차폐의 정도가 결과의 신뢰도 측면에 중요한 요인으로 작용하고 있음을 확인 할 수 있었다. 향후 외부 간섭에 따른 노이즈에 대한 추가적인 커패시턴스 차폐 연구가 필요한 것으로 판단된다.

• Journal of East-West Nursing Research
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• v.24 no.1
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• pp.1-9
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• 2018

Purpose: The purpose of this study was to identify nursing students' perception of patient rights, their ethical values and biomedical ethics awareness, and to examine the factors affecting the nursing students' biomedical ethics awareness. Methods: The participants of this study were 273 nursing students in B and K metropolitan city. Data collection was conducted through the structured questionnaires from March 2 to March 25, 2016. Data were analyzed using t-test, ANOVA, Scheffe's test, Pearson's correlation coefficient, and multiple regression analysis with SPSS WIN v 21.0. Results: The mean scores of nursing students' perception of patient rights, ethical values and biomedical ethics awareness were $4.56{\pm}0.38$, $3.26{\pm}0.31$, $2.91{\pm}0.20$, respectively. Biomedical ethics awareness was positively correlated with the nursing students' perceptions of patient rights (r=.38, p<.001) and ethical values (r=.25, p<.001). Factors affecting the nursing students' biomedical ethics awareness were the perception of patient rights (${\beta}=.36$, p<.001) and ethical values (${\beta}=.13$, p=.023). Conclusion: The results suggest that nursing educational program should include perception of patient rights and ethical values to foster biomedical ethics awareness for nursing students.