• Title/Summary/Keyword: biologocal

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Subacute Oral Toxicity of the Methanol Extract from Phellinus pini in Rats

  • Hong, Yun-Jung;Jang, Hyun-Jin;Yang, Ki-Sook
    • Natural Product Sciences
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    • v.17 no.4
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    • pp.291-295
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    • 2011
  • The present investigation evaluated the safety of the methanol extract from the fruit body of Phellinus pini Ames (PPA) by determining its potential toxicity after a subacute administration in rats. The extract was orally administered in doses of 1 g/kg, 2 g/kg, and 4 g/kg daily for 14 days to rats. Body weight, biochemical, and hematological parameters were determined at the end of 14 days of daily administration. The no-observed adverse effect levels (NOAEL) of the extract were 4 g/kg, when given by gavage routes. Daily oral administration of PPA extract for up to 14 days did not result in the death of significant changes in the body weight, hematological, and mainly biological parameters. In biological analysis, some significant changes occurred, including triglyceride and blood urea nitrogen (BUN), indicating that the PPA extract has liver and kidney-modulating activity. The PPA extract was found to be low or non-toxic in rats.

Environmental features of the distribution areas and climate sensitivity assesment of Korean Fir and Khinghan Fir (구상나무와 분비나무분포지의 환경 특성 및 기후변화 민감성 평가)

  • Park, Hyun-Chul;Lee, Jung-Hwan;Lee, Gwan-Gyu;Um, Gi-Jeung
    • Journal of Environmental Impact Assessment
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    • v.24 no.3
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    • pp.260-277
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    • 2015
  • The object of this study was the climate change sensitivity assessment of Korean Fir and Khinghan Fir as a representative subalpine plant in South Korea. Using species distribution models, we predicted the probability of current and future species distribution. According to this study, potential distribution that have been predicted based on the threshold (MTSS) is, Khinghan Fir was higher loss rate than Korean Fir. And in the climate change sensitivity assessment using the scalar sensitivity weight ($W_{is}$), $W_{is}$ of Korean Fir was higher relatively than the sensitivity of Khinghan Fir. When using the species distribution models as shown in this study may vary depending on the probability of presence data and spatial variables. Therefore should be prior decision studies on the ecological environment of the study species. Based on this study, if it is domestic applicable climate change sensitivity assessment method is developed. it would be important decision-making to climate change and biological diversity of adaptation policy.

Impact of Climate Change on Habitat of the Rhynchocypris Kumgangensis in Pyungchang River (기후변화가 평창강 금강모치의 생태서식 환경에 미치는 영향 평가)

  • Kim, Soojun;Noh, Hui Seong;Hong, Seung Jin;Kwak, Jae Won;Kim, Hung Soo
    • Journal of Wetlands Research
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    • v.15 no.2
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    • pp.271-280
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    • 2013
  • This study tried to analyze the impact of climate change on ecological habitat. In this regard, the Rhynchocypris Kumgangensis was selected among the CBIS(Climate-sensitive Biologocal Indicator Species) suggested by the Ministry of Environment. And ecological habitat and restrictive conditions for its survival was surveyed. Future runoff and water quality in the upstream of Pyungchang river were simulated by appling climate change scenarios to SWAT model which is able to simulate water quality. The estimated results explained characteristics on the increase of runoff, BOD, and water temperature and the decrease of DO in the future. The restrictive condition on ecological habitat of the Rhynchocypris Kumgangensis was used water quality during the April to May spawning season since BOD and DO were satisfactory as the first grade of water criteria in the estimated result of future water quality. As a result, it was analyzed that habitat of the Rhynchocypris Kumgangensis in the present was possible about 50~60% of the river. But the habitat would be decreased gradually in the future and would be possible in a very small part of the river in the long term.