• Title/Summary/Keyword: biological indices

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Optimization of Finite Element Retina by GA for Plant Growth Neuro Modeling

  • Murase, H.
    • Agricultural and Biosystems Engineering
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    • v.1 no.1
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    • pp.22-29
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    • 2000
  • The development of bio-response feedback control system known as the speaking plant approach has been a challenging task for plant production engineers and scientists. In order to achieve the aim of developing such a bio-response feedback control system, the primary concern should be to develop a practical non-invasive technique for monitoring plant growth. Those who are skilled in raising plants can sense whether their plants are under adequate water conditions or not, for example, by merely observing minor color and tone changes before the plants wilt. Consequently, using machine vision, it may be possible to recognize changes in indices that describe plant conditions based on the appearance of growing plants. The interpretation of image information of plants may be based on image features extracted from the original pictorial image. In this study, the performance of a finite element retina was optimized by a genetic algorithm. The optimized finite element retina was evaluated based on the performance of neural plant growth monitor that requires input data given by the finite element retina.

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Predicting tissue-specific expressions based on sequence characteristics

  • Paik, Hyo-Jung;Ryu, Tae-Woo;Heo, Hyoung-Sam;Seo, Seung-Won;Lee, Do-Heon;Hur, Cheol-Goo
    • BMB Reports
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    • v.44 no.4
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    • pp.250-255
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    • 2011
  • In multicellular organisms, including humans, understanding expression specificity at the tissue level is essential for interpreting protein function, such as tissue differentiation. We developed a prediction approach via generated sequence features from overrepresented patterns in housekeeping (HK) and tissue-specific (TS) genes to classify TS expression in humans. Using TS domains and transcriptional factor binding sites (TFBSs), sequence characteristics were used as indices of expressed tissues in a Random Forest algorithm by scoring exclusive patterns considering the biological intuition; TFBSs regulate gene expression, and the domains reflect the functional specificity of a TS gene. Our proposed approach displayed better performance than previous attempts and was validated using computational and experimental methods.

3D-QSAR Analysis and Molecular Docking of Thiosemicarbazone Analogues as a Potent Tyrosinase Inhibitor

  • Park, Joon-Ho;Sung, Nack-Do
    • Bulletin of the Korean Chemical Society
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    • v.32 no.4
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    • pp.1241-1248
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    • 2011
  • Three dimensional quantitative structure-activity relationships (3D-QSARs) between new thiosemicarbazone analogues (1-31) as a substrate molecule and their inhibitory activity against tyrosinase as a receptor were performed and discussed quantitatively using CoMFA (comparative molecular field analysis) and CoMSIA (comparative molecular similarity indices analysis) methods. According to the optimized CoMSIA 2 model obtained from the above procedure, inhibitory activities were mainly dependent upon H-bond acceptor favored field (36.5%) of substrate molecules. The optimized CoMSIA 2 model, with the sensitivity of the perturbation and the prediction, produced by a progressive scrambling analysis was not dependent on chance correlation. From molecular docking studies, it is supposed that the inhibitory activation of the substrate molecules against tyrosinase (PDB code: 1WX2) would not take place via uncompetitive inhibition forming a chelate between copper atoms in the active site of tyrosinase and thiosemicarbazone moieties of the substrate molecules, but via competitive inhibition based on H-bonding.

Study on the Benthic Macroinvertebrates in the Middle Reaches of the Paenae Stream , a Tributary of the Naktong River , Korea (배내천 中流의 底棲性 大形無脊椎動物에 대한 硏究 1. 群集分析 및 生物學的 水質 判定)

  • Oh, Yong-Nam;Tae-Soo Dhon
    • The Korean Journal of Ecology
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    • v.14 no.3
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    • pp.345-360
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    • 1991
  • Benthic macroinvertebrates were collecte in the middle reaches of the paenae stream, a tributary of th naktong river in korea, in four seasons from August 1989. To may 1990, during the study period, 125 species, 81 genera and 41 families were collected. Overall, the most dominant species was lepidostoma sp. 1 followed by heptagenia kihada, neoperla quadrata, diamesa sp. 1, ect.. the community was most diverse in autumn, However the number of collectd individuals was highest in winter. Species of chironomids including diamesa sp. 1 and mayflies including paraleptophlebia chocorata were collected exceptionally in a large number in winter. Seasonal occurrence of funtional groups such as collectors, shredders and scrapers was related with the availadlity of food sourses in the stream. The abundance of predators was relatively stable in four seasons with 17% on average. Diversity, tbi and chandler's biotic score(bs) in the paenae strem were 3.75, 14.5, and 100 on average, respectively. Based on biological and chemical indices the paenae stream was clean in the range of xeno- and oligo- saprobity.

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Classification of rural villages based on Landscape Indices - Focusing on Landscape Ecological Aspects - (경관지수를 활용한 농촌마을 유형분류: 경관생태학적 접근)

  • Kim, Han-Soo;Oh, Choong-Hyeon
    • Journal of Korean Society of Rural Planning
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    • v.17 no.3
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    • pp.1-13
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    • 2011
  • This study aims to analyse the landscape ecological characteristics of 39 rural villages in Korea and classify them according to their characteristics. After producing a land-use map of rural villages, this study quantified the landscape ecological characteristics of the subject sites as 18 landscape indexes using Fragstats. By applying the landscape index as a variable, selecting 4 factor through principal component analysis and conducting a cluster analysis, it classified them into 3 groups. Rural villages of Korea have their unique types of land-use due to the influence of physical environment such as geography, climate and ecology as well as the social and cultural influence, and the characteristics of land-use can be analysed and classified using the landscape index, the quantified landscape ecological characteristics.

Historical Control Data for Developmental Toxicity Study in Sprague-Dawley Rats (Sprague-Dawley 랫드를 이용한 발생독성시험의 기초자료연구)

  • 김종춘;이상준;배진숙;박종일;김용범;정문구
    • Toxicological Research
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    • v.17 no.2
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    • pp.83-90
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    • 2001
  • The background control data were compiled from rat developmental toxicity studies con-ducted at Toxicology Research Center, KRICT during the 1993-1999 period. These data were assembled in order to provide background in formation for the maternal and fetal data collected in 13 developmental toxicity studies using Sprague-Dawley rats. A total of 325 mated females were used in these studies during the seven-year period and overall pregnancy rate of these females was 93.8%. The present background control data included body weights, food consumption, hematological values, and organ weights of pregnant females, caesarean section data, and fetal examination data. These data can be used not only as a historical database for the meaningful interpretation of data from reproductive and developmental toxicity studies, but also as a contribution to biological characterization oj Sprague-Dawley rats.

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Optical Characteristics of Bimetallic Silver-Gold Film Structure in Surface Plasmon Resonance Sensor Applications (표면 플라즈몬 공명 센서에서의 쌍금속 은-금 박막 구조의 광학 특성)

  • Gwon, Hyuk-Rok;Lee, Seong-Hyuk
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.1
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    • pp.156-160
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    • 2007
  • Surface plasmon resonance(SPR) has been widely studied for biological and chemical sensing applications. The present study conducts numerical simulation for the single and bimetallic layer SPR configurations by using the multiple beam interference matrix(MBIM) method to investigate the influence of wave interference and complex refractive indices of materials on optical characteristics such as reflectance and optical phase shift which are used for sensing. First, calculated reflectances are compared with experimental data for validation. In addition, in the single film structures this study finds out the appropriate film thicknesses with minimum reflectance for cases of gold film and silver film. For a bimetallic silver-gold film structure, in particular, the bimetallic film thicknesses that has the minimum reflectance are found 36 nm for silver and 5 nm for gold. From the results, the use of phase shift would be useful compared to reflectance in determining the SPR configuration because the phase shift becomes more sensitive than reflectance.

The Application of a Genetic Algorithm with a Chromosome Limites Life for the Distribution System Loss Minimization Re-Configuration Problem

  • Choi, Dai-Seub
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.21 no.1
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    • pp.111-117
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    • 2007
  • This paper presents a new approach to evaluate reliability indices of electric distribution systems using genetic Algorithm (GA). The use of reliability evaluation is an important aspect of distribution system planning and operation to adjust the reliability level of each area. In this paper, the reliability model is based on the optimal load transforming problem to minimize load generated load point outage in each sub-section. This approach is one of the most difficult procedures and become combination problems. A new approach using GA was developed for this problem. GA is a general purpose optimization technique based on principles inspired from the biological evolution using metaphors of mechanisms such as natural selection, genetic recombination and survival of the fittest. Test results for the model system with 24 nodes 29 branches are reported in the paper.

Screening and effect of antagonists for biological control of plant pathogen (모잘록병의 생물학적 방제를 위한 유효 미생물 선발방법 및 효과)

  • Lee, Baek-Seok;Choe, Seong-Won;Choe, Gi-Hyeon;Lee, Jae-Ho;Kim, Eun-Gi
    • 한국생물공학회:학술대회논문집
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    • 2002.04a
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    • pp.386-389
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    • 2002
  • Antagonistic Bacillus sp. #16 to phytopathogenic fungi were selected based on the growth rate, inhibition rate and surface tension reduction. Based on the 16S rRNA sequences, Bacillus sp. #16 is closely related to the B. subtilis DSM10. In the pot test, Bacillus sp. #16 show the most effective growth inhibition against damping-off disease of cucumber seeding.

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