• Journal of Korean Biological Nursing Science
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• v.14 no.3
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• pp.147-155
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• 2012

Purpose: This study is to investigate perceived stress, depression, body mass index (BMI), and nutrient intakes of soldiers in the army. Methods: The subjects were 301 soldiers recruited from two divisions of the army in Kangwon-Do. The data was collected from August 3 to 9, 2009. Perceived stress, depression, lifestyle, dietary habits, BMI, and nutrient intake were assessed. Results: Subjects' distribution for normal weight, underweight, overweight, and obese was 67.4%, 0.7%, 16.3%, and 15.6%, respectively. BMI was related to class, service branch, duration of military service and being on a diet, whereas BMI was not found to be related to perceived stress, and depression. Some nutrient intakes such as dietary fiber, vitamin C, and Calcium was related to depression. Conclusion: This study suggests that soldiers need to undergo stress, depression management, and a nutritional education program.

• Animal Systematics, Evolution and Diversity
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• v.14 no.3
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• pp.229-242
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• 1998

The faunal survey on anthozoans of Geojedo Island was conducted from 17 localities of the adjacent waters of Geojedo Island during the period from February 1995 to Januray 1998. As a result, 39 species, 25 genera, 21 families, 7 orders, 3 subclasses in class Anthozoa were identified. Two of them, Callicatis japonica and Nemanthus nitidus are new to the Korean fauna.

• Mycobiology
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• v.51 no.5
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• pp.320-332
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• 2023

Talaromyces is a genus within the phylum Ascomycota (class Eurotiomycetes, order Eurotiales, family Trichocomaceae). Many species in this genus are known to produce diverse secondary metabolites with great potential for agricultural, medical, and pharmaceutical applications. During a survey on fungal diversity in the genus Talaromyces in Korea, six strains were isolated from soil, indoor air, and freshwater environments. Based on morphological, physiological, and multi-locus (ITS, BenA, CaM, and RPB2) phylogenetic analyses, we identified five previously unrecorded species in Korea (T. brevis, T. fusiformis, T. muroii, T. ruber, and T. soli) and a new species (T. echinulatus sp. nov.) belonging to section Talaromyces. Herein, detailed descriptions, illustrations, and phylogenetic tree are provided.

• Korean Journal of Biological Psychiatry
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• v.6 no.1
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• pp.3-11
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• 1999

At the beginning, researches on the biology of depression or affective illness have focused mainly on the receptor functions and neuroendocrine activities. And the studies of the past years did not break new theoretical background, but the recent advances in the research on the molecular mechanisms underlying neural communication and signal transduction do add some insights to many established ideas. This article will overview some of the more recent advances in the clinical researches of depression. Our major concerns to be presented here include the followings : (1) alterations in the post-synaptic neural transduction ; (2) changes in the neurons of hypothalamic neuropeptides ; (3) decreased peptidase enzyme activities ; (4) associations of hypothalamic-pituitary-adrenal axis abnormalities with serotonin neurotransmission ; (5) role of serotonin transporter ; (6) changes in the responsiveness of intracellular calcium ion levels ; (7) the inositol deficiency theory of lithium and depression ; (8) the transcription factors including immediate early genes ; (9) recent genetic studies in some families. This brief overview will suggest that changes in DNA occur during antidepressant therapy. These changes at the DNA level initiating a cascade of events underlying antidepressant modality will give us the insights on the molecular biological basis of the pathogenesis of depression and cues for a new class of antidepressants.

• BMB Reports
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• v.53 no.9
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• pp.453-457
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• 2020

The right-handed double-helical structure of DNA (B-DNA), which follows the Watson-Crick model, is the canonical form of DNA existing in normal physiological settings. Even though an alternative left-handed structure of DNA (Z-DNA) was discovered in the late 1970s, Z-form nucleic acid has not received much attention from biologists, because it is extremely unstable under physiological conditions, has an ill-defined mechanism of its formation, and has obscure biological functions. The debate about the physiological relevance of Z-DNA was settled only after a class of proteins was found to potentially recognize the Z-form architecture of DNA. Interestingly, these Z-DNA binding proteins can bind not only the left-handed form of DNA but also the equivalent structure of RNA (Z-RNA). The Z-DNA/RNA binding proteins present from viruses to humans function as important regulators of biological processes. In particular, the proteins ADAR1 and ZBP1 are currently being extensively re-evaluated in the field to understand potential roles of the noncanonical Z-conformation of nucleic acids in host immune responses and human disease. Despite a growing body of evidence supporting the biological importance of Z-DNA/RNA, there remain many unanswered principal questions, such as when Z-form nucleic acids arise and how they signal to downstream pathways. Understanding Z-DNA/RNA and the sensors in different pathophysiological conditions will widen our view on the regulation of immune responses and open a new door of opportunity to develop novel types of immunomodulatory therapeutic possibilities.

• BMB Reports
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• v.47 no.11
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• pp.599-608
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• 2014

As the prevalence of obesity has increased explosively over the last several decades, associated metabolic disorders, including type 2 diabetes, dyslipidemia, hypertension, and cardiovascular diseases, have been also increased. Thus, new strategies for preventing and treating them are needed. The nuclear peroxisome proliferator-activated receptors (PPARs) are involved fundamentally in regulating energy homeostasis; thus, they have been considered attractive drug targets for addressing metabolic disorders. Among the PPARs, $PPAR{\gamma}$ is a master regulator of gene expression for metabolism, inflammation, and other pathways in many cell types, especially adipocytes. It is a physiological receptor of the potent anti-diabetic drugs of the thiazolidinediones (TZDs) class, including rosiglitazone (Avandia). However, TZDs have undesirable and severe side effects, such as weight gain, fluid retention, and cardiovascular dysfunction. Recently, many reports have suggested that $PPAR{\gamma}$ could be modulated by post-translational modifications (PTMs), and modulation of PTM has been considered as novel approaches for treating metabolic disorders with fewer side effects than the TZDs. In this review, we discuss how PTM of $PPAR{\gamma}$ may be regulated and issues to be considered in making novel anti-diabetic drugs that can modulate the PTM of $PPAR{\gamma}$.

• ALGAE
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• v.23 no.4
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• pp.289-294
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• 2008

To estimate seaweed biomass or standing crop, a nondestructive sampling can be beneficial because of not much destroying living plants and saving time in field works. We suggest a methodological procedure to estimate seaweed biomass per unit area in marine benthic habitats by using species-specific regression equations. Percent cover data are required from the field samplings for most species to convert them to weight data. However, for tall macroalgae such as kelps we need density data and their size (e.g., size class for subtidal kelps) of individuals. We propose that the field sampling should be done with 5 replicates of 50 cm x 50 cm quadrat at three zones of intertidals (upper, middle, lower) and three depth points (1, 5, 10 m) in subtidals. To obtain a reliable regression equation for a species, a substantial number of replicate is necessary from destructive samplings. The regression equation of a species can be further specified by different locality and different season, especially for the species with variable morphology temporally and spatially. Example estimation carried out in Onpyung, Jeju Island, Korea is provided to compare estimated values with real weight data.

• 한국약용작물학회:학술대회논문집
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• 2009.05a
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• pp.387-388
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• 2009

• Communications of the Korean Mathematical Society
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• v.26 no.2
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• pp.321-338
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• 2011

In this paper, a class of delayed epidemic model with diffusion is investigated. By analyzing the associated characteristic transcendental equation, its linear stability is investigated and Hopf bifurcation is demonstrated. Some explicit formulae determining the stability and the direction of the Hopf bifurcation periodic solutions bifurcating from Hopf bifurcations are obtained by using the normal form theory and center manifold theory. Some numerical simulation are also carried out to support our analytical findings. Finally, biological explanations and main conclusions are given.

• Proceedings of the PSK Conference
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• 2003.10a
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• pp.75-78
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• 2003

Polyketides are a class of structurally diverse natural products which possess a wide range of biological activities. These compounds are used throughout medicine and agriculture as antimicrobials, immunosuppressants, antiparasitics, and anticancer agents. While structurally diverse, polyketides are assembled by a common mechanism of decarboxylative condensations of simple malonate derivatives by polyketide synthases (PKSs) in a manner very similar to fatty acid biosynthesis (Fig 1). (omitted)