• 제목/요약/키워드: biochemical

검색결과 6,756건 처리시간 0.04초

Lipase를 이용한 함불소화합물의 광학분할 (Biochemical Resolutions of Organic Florine Compounds Using Lipase)

  • 손태일;키타쯔메 도모야
    • 공업화학
    • /
    • 제5권1호
    • /
    • pp.176-181
    • /
    • 1994
  • 시판되고 있는 4종류의 Lipase(talpase, paratase M1000L, SP398, SP435)를 이용하여, 2-[1-(1-acetoxy-2, 2, 2-trifluoroethyl)]-5-trimethylsilylfuran(1)을 속도론적 광학분할에 의해서 가수분해반응을 검토했다. 그 결과 Novo Nordish사의 SP435가 속도론적 광학분할능을 가진다는 것을 확인했으며, 본 실험에서는 광학순도 92.4% enantiomeric excess(ee)를 가지는 생성물 2-[1-(2, 2, 2-trifluoro-1-hydroxyethyl)]-5-trimethylsilyfuran(2)를 얻었다.

  • PDF

치매에 관한 최근의 연구 동향 (The latest development in Dementia)

  • 나창수;김정상;채우석;박석천
    • 대한한방내과학회지
    • /
    • 제19권1호
    • /
    • pp.291-300
    • /
    • 1998
  • Dementia is the neurodegenerative process that affects cognition, behavior and function and one of the most prominent diseases of dementia is Alzheimer's disease(AD). AD is a dementing illness characterized clinically by the progressive and irreversible deafferentation of the limbic system, association neocortex and basal forebrain. A number of conditions are known to be predisposing risk factors for AD. In several of these, initiation of glial-mediated inflammatory pathways as a mechanism of AD is getting a lot of attention. On the other hand, a biochemical marker for monitoring the onset and progression of the disease would be a valuable tool for disease management. Also such a marker might be used as an end point in clinical intervention protocols. This biochemical marker will have the potential for identifying subjects afflicted with the disease and possibly for monitoring the onset and longitudinal progression of the disease. Here we have reviewed the latest papers of different approaches to AD. Of course, there is a section of PET which is very useful clinically nowadays.

  • PDF

제주지방 돼지의 폐병변으로부터 Pasteurella multocida 분리 및 생화학적 특성 (Isolation and Biochemical Properties of Pasteurella multocida from the pneumonic lungs of swine in Cheju)

  • 김옥녀;이두식;문호규;김우택;서문현;배종희;임윤규;조길재
    • 한국동물위생학회지
    • /
    • 제18권2호
    • /
    • pp.124-132
    • /
    • 1995
  • The present study was conducted to investigate the incidence of Pasteurella multocida infection in cheju swine from March 1994 to December 1994 isolated organisms were identified by the biochemical properties, cellulose serological type and antibiotic susceptibilities. Pasteurella multocida was isolated from the Lungs of 96 pigs with pneumonia(51 %) among 188 slaughtered pigs. The majority of p multocida isolates were identical to those of the standard strains. On the classification of the capsular type of the isolated p multocida it consist of the 88 isolates of type A(91.6%) 2 isolates of type D (2%) and un classified 6 types(6.2%). The majority of the 96 isolates of p multocida highly susceptible to the antibiotics including ampicillin(Am), cephalotin(Ce), erythromycin(Em), gentamycin(Gm), kanamycin(Km), lincomycin(Lm), neomycin(Nm), penicillin(Pc), streptomycin(Sm), solfametoxazol/trimethoprim(Sxt) and tetracycline(Te)

  • PDF

Lipopeptides Extract from Bacillus Amyloliquefaciens Induce Human Oral Squamous Cancer Cell Death

  • Kuo, Chen-Hui;Lin, Yun-Wei;Chen, Ruey-Shyang
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제16권1호
    • /
    • pp.91-96
    • /
    • 2015
  • A lipopeptide extract of Bacillus amyloliquefaciens BACY1 (BLE) was found to induce cell death in human oral squamous cell carcinoma (OSCC) cell lines, SCC4 and SCC25, in this study. The results of MTT assay showed that BLE inhibited OSCC cell proliferation in a dose-dependent manner. BLE was also effective in increasing the sub-G1 phases. Furthermore, when membrane damage in SCC4 cells treated with BLE was monitored by LDH assay, release of LDH was significantly increased. The protein and mRNA levels of pro-apoptotic Bax, and caspase-3 were up-regulated by BLE. Taken together, these results suggest that BLE induces apoptosis and then inhibits the cell proliferation of human OSCC cells.

Effect of Working on Physiological, Biochemical and Haematological Parameters in Hariana Bullocks

  • Yadav, A.S.;Dhaka, S.S.;Kumar, B.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제14권8호
    • /
    • pp.1067-1072
    • /
    • 2001
  • An experiment was conducted on eight bullocks of Hariana cattle study draft efficiency using different appliances, changes in their physiological, biochemical and haematological parameters, and how the body tries to maintain these within normal physiological range. Blood collection was done at pre-exercise, three hours after exercise and two hours post exercise in summer and winter seasons of the year 1990-91. Average pulse rate and respiration rate per minute were found to be $63.09{\pm}0.78,\;25.60{\pm}0.54,\;97.21{\pm}2.51,\;63.37{\pm}2.70,\;64.05{\pm}1.90,\;25.33{\pm}1.20$, respectively, at pre-exercise, three hours exercise and two hours post exercise rest. The seasonal differences were found to significant and the values were higher in summer than in winter. After two hours post exercise rest Hariana bullocks regained their normal values for all the parameters, except that pulse rate, respiration rate and serum sodium during summer did not reach the pre - exercise levels.

소시호합육미지황탕(小柴胡合六味地黃湯)이 간의 생화학적 이상에 미치는 영향에 대한 임상보고 (The Effects of SosihohapYukmijihwang-tang Administration on biochemical abnormality of Liver)

  • 김원찬;이지영;김진아;장혜진
    • 대한한방내과학회지
    • /
    • 제27권4호
    • /
    • pp.999-1006
    • /
    • 2006
  • Objectives:The purpose of this study was to examine the efficacy of SosihohapYukmijihwang-tang on seven patients with biochemical abnormality of the liver. Methods: SosihohapYukmijihwang-tangwas administered to patients for over 10 days continuously. Tests of their AST, ALT, r-GTP, ALP were taken before and after taking medicine. Results: Through this method, we found a positive effect of taking this herbal medicine on biochemical abnormality of the liver. Conclusions: The results suggest that taking this herbal medicine not only reduces hepatotoxicity, but also improves liver function. We need more study about this.

  • PDF

저수온기 돔류의 녹간증 혈청성분 (Biochemical analysis of blood serum from wintering seabream with green liver syndrome)

  • 최혜승;박승렬;정춘구
    • 한국어병학회지
    • /
    • 제15권1호
    • /
    • pp.43-48
    • /
    • 2002
  • A blood biochemical analysis was carried out for the serum of wintering sea bream (red sea bream Pagrus major, black sea bream Acanthopagrus schlegeli, rock bream Oplegenathus fasciantuas) with green liver syndrome. GOT and GPT were significantaly elavated in the diseased sea bream. The value of $NH_{3}$ was slightly higher but those of TBIL. TP and UA were lower than the control. But there were no differences in albumin. Ca and glucose between the diseased and the control. These results suggent that a green liver syndrome in the sea bream might be related with nutritional defects and the stress of low water temperature during the winter.

수중(水中) 수은(水銀) 및 鉛(연)의 농도(濃度)가 BOD값에 미치는 영향(影響)에 관(關)하여 (Effect of Mercury and Lead on the Biochemical Oxygen Demand (BOD))

  • 문재동
    • Journal of Preventive Medicine and Public Health
    • /
    • 제17권1호
    • /
    • pp.217-221
    • /
    • 1984
  • In order to estimate interfering effects of mercury and lead on biochemical oxygen demand (BOD), BOD in 18 effluent samples were measured under three different concentrations of mercury and lead. The results obtained were as follows: 1. Biochemical oxygen demand(BOD) was decreased under the presence of mercury and lead, with parallel correlation of mercury concentration. 2. High correlations were noted between original BOD concentration and decreasing amount of BOD when concentrations of mercury or lead were increased. 3. When the lead concentration was high, the close correlation was observed between total organic carbon(TOC) and decreasing amount of BOD. 4. There was a negative correlation between TOC/BOD ratio and decreasing amount of BOD when the mercury concentrations were high.

  • PDF

옥신 호르몬 결합단백질 ABP57 유전자를 이용한 작물의 형질개선 (Improvement of crop traits using auxin binding protein gene abp57)

  • 김동헌;이근표
    • Journal of Plant Biotechnology
    • /
    • 제38권2호
    • /
    • pp.137-142
    • /
    • 2011
  • Auxin is a group of small natural and synthetic molecules having diverse regulatory functions in plant growth and development. In this review, two auxin binding proteins identified by biochemical experiments to measure their auxin binding activities and biochemical functions are described. ABP1, a 22 kDa auxin binding protein, shows strong auxin binding affinity and possibly plays an important role in plant development, although its biochemical function are still unclear. ABP57, a 57 kDa soluble protein from rice shoots, has both of IAA binding activity and the plasma membrane proton pump activation. Although it is yet to be accomplished, the improvement of agronomic traits using auxin binding proteins is worth to be considered, since auxin is known to be related to such a diverse crop traits.

도축장 출하축의 폐병변에서 분리한 Pasteurella multocida의 생화학적 특성 및 약제감수성 (Biochemical properties and antimicrobial susceptibility of Pasteurella multocida isolated from pneumonic lungs in slaughtered animals)

  • 김성국;이양수;정종식;김수웅
    • 한국동물위생학회지
    • /
    • 제22권1호
    • /
    • pp.79-84
    • /
    • 1999
  • This study was carried out to investigate isolation of Pasteurella multocida from pneumonic lungs of slaughtered animals in Kyungsan abattoir to examine the antimicrobial susceptibility and biochemical properties. The results were summarized as follows ; P multocida was isolated from 50(29.2% ) of the 171 pneumonic lungs collected individually from cattle(3/40), goats(0131) and pigs(47/100), All of the isolated P multocida showed biocemical and cultural properties similiar to reference strains. All isolates were very susceptible to AK, AM, ENR, CF, GM,07, whereas resistant to SDM.

  • PDF