• 펄프종이기술
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• 제46권6호
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• pp.63-70
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• 2014

Part of SB latex in pre-coating color was substituted with newly developed starch-based bio-binder in order to investigate the effect of starch-based bio-binder in pre-coating color on the properties of coating color and coated paper. Smoothness and gloss of coated paper were decreased with the increase of bio-binder substitution ratio. Brightness and whiteness did not show the significant changes, but stiffness was improved with bio-binder. Ink set-off, dry-pick and wet pick were decreased with the increase of bio-binder substitution ratio. In general, when all SB latex is substituted with bio-binder, ink set-off, dry- and wet-pick were deteriorated. However, it was found that if the bio-binder substitution ratio is controlled below 50%, similar qualities with coated paper manufactured by the use of SB latex binder can be obtained.

• 한국산업융합학회 논문집
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• 제20권5호
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• pp.359-364
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• 2017

A machine such as bean crusher machine is subjected to different loads and vibration. Due to this vibration there will be certain deformations which affect the performance of the machine in adverse manner. This paper proposed a vibration analysis of bean crusher machine using ANSYS. The Finite Element Method (FEM) analysis is carried out to study the effect of vibration on the structure in order to ensure the safety. This work helps the machine developer make a better product at the early design stage with lower cost and faster development time. To do this, firstly, using Inventor, a CAD model is prepared. Secondly, the analysis is to be carried out using ANSYS 15. The modal analysis and random vibration analysis of the structure was conducted. The analysis shows that the proposed design was successfully shows the minimum deformation when the vibration was applied in normal condition.

• 한국산업융합학회 논문집
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• 제21권5호
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• pp.247-255
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• 2018

In this research, the effect of normal load, sliding velocity, and texture density on thefriction coefficient of surfaces micro-textured on AISI 4140 under paraffin oil lubrication were investigated. The predicted tribological behavior by numerical calculation can be serves as guidance for the designer during the machine development stage. Therefore, in this research friction coefficient prediction model based on response surface methodology (RSM), support vector machine (SVM), and artificial neural network (ANN) were developed. The experimental result shows that the variation of load, speed and texture density were influence the friction coefficient. The RSM, ANN and SVM model was successfully developed based on the experimental data. The ANN model can effectively predict the tribological characteristics of micro-textured AISI 4140 in paraffin oil lubrication condition compare to RSM and SVM.

• 한국펄프종이공학회:학술대회논문집
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• 한국펄프종이공학회 2011년도 추계학술발표회 논문집
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• pp.59-72
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• 2011

• Bulletin of the Korean Chemical Society
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• 제31권12호
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• pp.3507-3508
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• 2010

• Ocean and Polar Research
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• 제39권3호
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• pp.233-244
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• 2017

This study seeks to analyze the needs of biotechnology companies in relation to their entry into the marine biotechnology industry and to discuss the policy implications associated with empirical tasks based on issues raised from empirical results gathered from a survey data of 200 biotechnology companies in Korea. This study made a comparison between marine and non-marine biotechnology companies and analyzed non-marine biotechnology companies' needs related to their entry into the marine biotechnology companies by using Social Network Analysis (SNA). Empirical results indicate that 23.5% of biotechnology companies produce goods using marine bio-resources. Once the utility of marine bio-resources is established, 58.8% of non-marine biotechnology companies intend to enter the marine biotechnology industry. This study also shows that non-marine biotechnology companies need technical support, information sharing, and the acquisition of raw materials to enter the marine biotechnology industry. The findings in this study provide important pointers for the direction of policies and future research in the area of marine biotechnology industry.

• 광산업정보
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• 통권49호
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• pp.16-19
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• 2008

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2017년도 춘계공동학술대회
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• pp.123-123
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• 2017

식물공장 내 작물의 생육은 제공되는 인공광원의 광원 및 광질에 영향을 받으며, 광흡수 파장에 따라 다르다. 또한 광합성에 효과적인 형태의 빛의 계속적인 빛의 조사보다는 광 펄스를 조절하여 공급하여 준다면 더욱더 효과적인 생육 환경을 제공해 줄 수 있다. 식물의 최적 생장을 위해 특정 파장대의 빛을 선택적으로 조사할 수 있는 LED특성을 사용하여 UV광원을 포함한 인공광원의 펄스폭 변조에 따른 적치마 상추의 생육특성을 알아보고자 하였다. 광환경은 Red(660 nm), Blue(450 nm), UV(395 nm) LED를 8:1:1 비율로 광량 $160{\mu}mol{\cdot}m^2{\cdot}s^{-1}$, 주파수 1.25, 2.5, 3.75, 5.0 kHz로 조사하여 주었으며, 온도 $20{\sim}23^{\circ}C$, 습도 50~60%, $CO_2$농도 1,000 ppm으로 조성하여 주었다. 아시아종묘 적치마상추를 파종 후 18일 째 되는날 정식, 정식 후 14일 28일 째 되는날 SPAD, 지상부 지하부의 생체중 및 건물중, 엽폭, 엽장을 측정하였으며, 측정한 엽폭과 엽장을 이용하여 엽형지수 산출, 지상부 지하부 생체중 값을 이용하여 S/R율을 산출하였다. SPAD 측정결과 생육시기가 증가할수록 SPAD함량은 감소하였으며, 1.25와 2.5 kHz에서 생육 시기 증가에 대한 SPAD함량 감소가 컸고, 3.75와 5.0 kHz의 경우 SPAD함량의 감소량은 작았다. 지상부 생체중은 3.75 kHz에서 121.51 g으로 가장 높은 값을 나타냈으며, 2.5, 1.75, 5.0 kHz 순으로 높은 값을 나타났다. 지하부 생체중의 경우 3.75 kHz에서 31.31 g으로 가장 높은 값을 나타냈으며 2.5, 5.0, 1.25 kHz 순으로 높게 나타났다. 엽형지수는 생육 시기가 증가에 따라 감소하는 것으로 나타났으며, 1.75, 2.5, 5.0, 3.75 kHz 순으로 크게 나타났다. 지상부 건물중 측정결과는 지상부 생체중 결과와, 지하부 건물중의 측정결과는 지하부 생체중 결과와 동일하였다. S/R율은 1.75 kHz를 제외하고 생육시기가 증가할수록 S/R율은 감소하는 것으로 나타났으며, 주파수가 높아질수록 S/R율은 감소하는 것으로 나타났다. 엽형지수는 엽폭/엽장으로 엽형지수를 산출한 결과로 값이 작을수록 엽폭이 넓은 형태를 의미하며, 생체중값이 가장 크게 나타났던 3.75 kHz에서 엽형지수의 값이 가장 낮게 나타났으며 3.75 kHz를 제외하고 주파수가 높을수록 엽형지수의 값이 낮게 나타났다. 이에 주파수에 따른 적상추의 생육은 3.75 kHz에서 가장 좋은 것으로 판단할 수 있었다.

• 생명과학회지
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• 제19권2호
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• pp.249-255
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• 2009

Esculetin, a coumarin compound, has been known to inhibit proliferation and induce apoptosis in several types of human cancer cells. However, the molecular mechanisms involved in esculetin-induced apoptosis are still uncharacterized in human leukemia cells. In this study, we have investigated whether esculetin exerts anti-proliferative and apoptotic effects on human leukemia U937 cells. It was found that esculetin could inhibit cell viability in a time-dependent manner, which was associated with the induction of apoptotic cell death such as increased populations of apoptotic- sub G1 phase. Apoptosis of U937 cells by esculetin was associated with an inhibition of Bcl-2/Bax binding activity, formation of tBid, down-regulation of X-linked inhibitor of apoptotic protein (XIAP) expression, and up-regulation of death receptor 4 (DR4) and FasL expression. Esculetin treatment also induced the degradation of ${\beta}$-catenin and DNA fragmentation factor 45/inhibitor of caspase-activated DNase (DFF45/ICAD). Furthermore, a caspase-3 specific inhibitor, z-DEVD-fmk, significantly inhibited sub-G1 phase DNA content, morphological changes and degradation of ${\beta}$-catenin and DEE45/ICAD. These results indicated that a key regulator in esculetin-induced apoptosis was caspase-3 in human leukemia U937 cells.

• Journal of Applied Biological Chemistry
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• 제60권2호
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• pp.119-124
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• 2017

소나무 뿌리(동송근)로부터 phenolic compounds를 추출 후 미용식품활성을 검정하여 기능성 소재로 활용가능성을 살펴보았다. 동송근에 함유된 페놀성 물질의 tyrosinase 저해효과를 측정한 결과 $50{\mu}g/mL$ phenolics 농도에서 ethanol 추출물이 92%의 tyrosinase 저해효과를 나타내었다. Elastase와 collagenase 저해효과를 측정한 결과 $200{\mu}g/mL$ phenolics 농도에서 ethanol 추출물이 각각 61, 78%의 높은 저해력을 나타내어 주름개선효과가 높았다. 수렴효과는 $50{\mu}g/mL$ phenolics의 저농도 ethanol 추출물에서 82%의 저해효과를 나타내었다. 염증억제효과를 나타내는 hyaluronidase 저해효과를 측정한 결과 $100-200{\mu}g/mL$ phenolic 농도의 ethanol 추출물에서 74-94%의 매우 높은 염증억제효과를 나타내었다. 이러한 결과로 보아 동송근 추출물이 미용식품활성 또는 기능성 소재로서 활용이 가능할 것으로 판단되었다.