• 식품과학과 산업
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• 제41권2호
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• pp.53-57
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• 2008

• Molecules and Cells
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• 제38권9호
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• pp.789-795
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• 2015

A chromosome territory is composed of chromosomal subdomains. The internal structure of chromosomal subdomains provides a structural framework for many genomic activities such as replication and DNA repair, and thus is key to determining the basis of their mechanisms. However, the internal structure and regulating proteins of a chromosomal subdomain remains elusive. Previously, we showed that the chromosome territory expanded after BAF53 knockdown. Because the integrity of chromosomal subdomains is a deciding factor of the volume of a chromosome territory, we examined here the effect of BAF53 knockdown on chromosomal subdomains. We found that BAF53 knockdown led to the disintegration of histone H2B-GFP-visualized chromosomal subdomains and BrdU-labeled replication foci. In addition, the size of DNA loops measured by the maximum fluorescent halo technique increased and became irregular after BAF53 knockdown, indicating DNA loops were released from the residual nuclear structure. These data can be accounted for by the model that BAF53 is prerequisite for maintaining the structural integrity of chromosomal subdomains.

• 수산해양기술연구
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• 제54권1호
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• pp.81-88
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• 2018

A study for species composition and abundance of the fish assemblages in the eastern Jinhae Bay, Korea was conducted using monthly larval collection by a RN80 net from October, 2010 to September, 2011. Of all the 45 species collected, the dominant species were Clupea pallasii, Hexagrammos otakii, Pholis fangi and Engraulis japonicus. Clupea pallasii, Hexagrammos otakii, Pholis fangi in winter and examined Engraulis japonicus, Acanthogobius sp., Parablennius yatabei, and Tridentiger trigonocephalus in summer appeared seasonally. Popoulation characteristic by stations was not clear seasonally and spatially, and appearance aspects of dominant species were similar by stations. Compared our results with other studies in the South Sea, dominant species and their appearance period were similar to their spawning period. Finally, the appearance period of the larvae in the South Sea was closely resulted to spawning period rather than the regional characteristic.

• 한국환경과학회:학술대회논문집
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• 한국환경과학회 2008년도 추계학술발표회 발표논문집
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• pp.538-544
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• 2008

Activated protein C (APC) is thought to exert antiinflammatory activities through the endothelial protein C receptor (EPCR)-dependent cleavage of protease activated receptor 1 (PAR-1) in endothelial cells. Since thrombin cleaves PAR-1 with $\sim$3-4-orders of magnitude higher efficiency, and PAR-1 is a target for proinflammatory activities of thrombin, it is not understood how APC can elicit protective responses through the cleavage of PAR-1. In this study, we demonstrate that EPCR is associated with caveolin-1 in endothelial lipid rafts, but its occupancy by protein C leads to its dissociation from caveolin-1 and subsequent recruitment of PAR-1 to protective signaling pathways through the coupling of PAR-1 to Gi-protein. When EPCR is bound by protein C, the PAR-1-dependent protective response in endothelial cells can be mediated by either thrombin or APC. These results provide a new paradigm for understanding the mechanism through which PAR-1 and EPCR participate in cellular signaling events in endothelial cells.

• Journal of Microbiology and Biotechnology
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• 제26권5호
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• pp.823-828
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• 2016

The present study investigated the protective effect of naturally purified 4-(3,4-dihydroxyphenyl)-3-buten-2-one (DHP) from Phellinus linteus against naproxen-induced gastric antral ulcers in rats. To verify the protective effect of DHP on naproxen-induced gastric antral ulcers, various doses (1, 5, and 10 μg/kg) of DHP were pretreated for 3 days, and then gastric damage was caused by 80 mg/kg naproxen applied for 3 days. DHP prevented naproxen-induced gastric antral ulcers in a dose-dependent manner. In particular, 10 μg/kg DHP showed the best protective effect against naproxen-induced gastric antral ulcers. Moreover, DHP significantly attenuated the naproxen-induced lipid peroxide level in gastric mucosa and increased the activities of radical scavenging enzymes, such as superoxide dismutase, catalase, and glutathione peroxidase, in a dose-dependent manner. A histological examination clearly demonstrated that the gastric antral ulcer induced by naproxen nearly disappeared after the pretreatment of DHP. These results suggest that DHP can inhibit naproxen-induced gastric antral ulcers through prevention of lipid peroxidation and activation of radical scavenging enzymes.

• 수산해양기술연구
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• 제53권1호
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• pp.107-113
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• 2017

The feeding habits of larval (5.0~27.0 mm SL) Clupea pallasii were examined and 1,523 individuals were collected from November 2010 to March 2011 in the coastal water of Eastern Jinhae Bay, Korea. Larval C. pallasii were fed mainly on copepods that constituted 55.2% in IRI. Monogeneans were the second largest prey component, another prey items tintinnids, cladocerans and ostracoda. The results of analysis in ontogenetic changes exhibit high during the daytime, two small size classes (${\leq}10mm$, 10~15 mm) mainly fed copepods. while the percentage of coperpods decreased, monogeneans ratio increased in 15~20 mm size class. Feeding rate in diel difference of larval C. pallasii were high during the daytime.

• Advances in Traditional Medicine
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• 제10권4호
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• pp.288-293
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• 2010

Lindera erythrocarpa Makino (LE) is widely distributed on Jeju Island, where it has been used for various traditional therapies. Effects of a crude extract of LE were examined in rats with obesity induced by a high-fat diet (HFD). Anti-obesity effects were followed in rats receiving orally administered vehicle, 100mg/kg extract, or 250 mg/kg LE extract, for 56 days. LE extract (250 mg/kg) suppressed increases in body weight and epididymal fat, with amelioration of fatty changes in the liver. Additionally, serum levels of alanine aminotransferase, aspartate aminotransferase, and total cholesterol were significantly decreased compared with those of vehicle-treated groups (p < 0.05). These results suggest that oral administration of LE extract reduced rat obesity induced by HFD, possibly through the reduction of fat accumulation.

• 한국지역사회생활과학회지
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• 제24권2호
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• pp.187-194
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• 2013

The purpose of this study was to define the optimal boxthorn berries washing method for developing the boxthorn berries cleaner. We analyzed the rate of removal of residual pesticides according to washing methods; 1st - habitual washing method, 2nd - drum rotation washing method, 3th - drum rotation and air bubble washing method, 4th - drum rotation and nozzle spray washing method, 5th - drum rotation and air bubble and nozzle spray washing method. A rate of removal of residual pesticides of 88% was detected in the drum rotation and air bubble and nozzle spray washing method, and a rate of 82% was detected in the habitual washing method. The drum rotation and air bubble and nozzle spray washing method appeared to be the best good washing effect compared to the habitual washing method(about 6% compared to 82.0% higher). Clothianidin Triadimefon, Triforine ingredients, the drum rotation and air bubble and nozzle spray washing method efficiency was lower compared to the habitual washing method removal efficiency.

• 한국지역사회생활과학회지
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• 제25권3호
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• pp.383-388
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• 2014

This study was examined the physical characteristics (geometry, yield strength, thousand-seeds weight, true density, and moisture content) required for mechanization-related technologies such as (harvesting, washing, transport, and drying). Large differences in the size and shape of boxthorn berries(Jangmyeong, Bullo, Chungmyeong, and Hokwang) are used to analyze these physical properties. The average diameter, volume, surface area, and sphericity rate are calculated using long and short diameters of the boxthorn berry according to its variety. Hokwang has the largest measured surface area, and Bullo, the smallest. Average yield strength is 1.78 kPa and the mechanical pressure of soft boxthorn berries is not more than 1 kPa. Bullo has the highest true density. The optimum drying time for the measurement of moisture content is 4 hours at the drying temperature of $100^{\circ}C$.

• 한국식생활문화학회지
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• 제35권1호
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• pp.28-54
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• 2020

This study aims to investigate the food preservation methods adopted by the Joseon Dynasty, which existed before the 17^th century. A total of 232 food preservation methods were discovered in 25 books, and could be classified by their targeted food types: vegetables (84), sea foods (60), meats (41), fruits (37), and others (10). Depending on the preservation method applied, they are classified as food drying, soaking, mud cellar preservation, and other preservation. Food drying is further classified into 8 sub-types: drying, sun-drying, shadow-drying, wind-drying, dry heat, combined drying, smoking, and others. Soaking could be sub-divided into using salt, ash, dry sand, bran, fermented paste, wet distillers grains, oil, and others. Mud cellar preservation is sub-classified into installing shelf inside the mud cellar, making the mud cellar for food preservation, and making hole or underground tunnel for food preservation. Other food preservation methods include minimizing moisture loss by applying beeswax on a section of the vegetable stem, and cutting the vegetables or fruits with their branches and leaves for food preservation.