• Title/Summary/Keyword: bio materials

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Fabrication of Multi-layered Macroscopic Hydrogel Scaffold Composed of Multiple Components by Precise Control of UV Energy

  • Roh, Donghyeon;Choi, Woongsun;Kim, Junbeom;Yu, Hyun-Yong;Choi, Nakwon;Cho, Il-Joo
    • BioChip Journal
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    • v.12 no.4
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    • pp.280-286
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    • 2018
  • Hydrogel scaffolds composed of multiple components are promising platform in tissue engineering as a transplantation materials or artificial organs. Here, we present a new fabrication method for implementing multi-layered macroscopic hydrogel scaffold composed of multiple components by controlling height of hydrogel layer through precise control of ultraviolet (UV) energy density. Through the repetition of the photolithography process with energy control, we can form several layers of hydrogel with different height. We characterized UV energy-dependent profiles with single-layered PEGDA posts photocrosslinked by the modular methodology and examined the optical effect on the fabrication of multi-layered, macroscopic hydrogel structure. Finally, we successfully demonstrated the potential applicability of our approach by fabricating various macroscopic hydrogel constructs composed of multiple hydrogel layers.

The Synthesis and Characterization of Mesoporous Microbead Incorporated with CdSe/ZnS QDs (양자점이 고밀도화된 마이크로 비드의 제조 및 특성)

  • Lee, Ji-Hye;Hyun, Sang-Il;Lee, Jong-Huen;Koo, Eun-Hae
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.25 no.8
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    • pp.657-663
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    • 2012
  • The spherical mesoporous silica is synthesized and incorporated with CdSe/ZnS quantum dots(QDs) for preparing micro beads to detect toxic and bio-materials with high sensitivity. The spherical silica beads with the brunauer-emmett-telle(BET) average pore size of 15 nm were prepared with a ratio 1, 3, 5-trimethylbenzen, as a swelling agent, to the block-copolymer template surfactant of over 1 and under vigorous mixing condition. The surface of spherical mesoporous silica is modified using octadecylsilane for incorporating QDs. Based on photoluminescence(PL) spectra, the relative brightness of mesoporous silica beads incorporated with 10 nM of QDs is 79,000 times brighter than that of Rodamine 6 G.

A Study of Germination Characteristics of Dredged Soil Collected in Gunsan (군산 인근해역 준설토를 활용한 식생발아 특성 연구)

  • Kim, Dae-Hyeon;Yoon, Gil-Lim;Kim, Min-Seok;Park, Kyung-Ho
    • Journal of the Korean Geotechnical Society
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    • v.31 no.5
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    • pp.59-66
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    • 2015
  • This study aimed to analyze germination characteristics of dredged soil collected in Gunsan. This study develops the ecological environment materials for useable green soil that can be used in the stabilization of the dredged slope. In order to analyze the germination characteristics of dredged soil, specimens treated with Bio ameliorant (0, 6%), AC (Amino acid) ameliorant (0, 6%), Sawdust (0, 6%) and loess (0, 50%) were made. Based on the test results, it was found that dredged soils of Gunsan Saemangeum were classified as SM, and poor arboreal growth conditions were necessary to be treated with ameliorants (Sawdust, Bio ameliorant, etc.).

Fabrication and Characterization of CdSe/ZnS-QDs Incorporated Microbeads for Ultra-sensitive Sensor Applications (양자점을 이용한 고감도 마이크로 비드의 제조 및 특성)

  • Lee, Dong-Sup;Lee, Jong-Chul;Lee, Jong-Heun;Koo, Eun-Hae
    • Journal of the Korean Ceramic Society
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    • v.47 no.2
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    • pp.189-194
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    • 2010
  • Compared with organic fluorophores, semiconductor quantum dots (QDs) have the better properties such as photostability, narrow emission spectra coupled to tunable photoluminescent emissions and exceptional resistance to both photo bleaching and chemical degradation. In this work, CdSe/ZnS QDs nanobeads were prepared by the incorporation of CdSe/ZnS QDs with mesoporous silica to use as the optical probe for detecting toxic and bio- materials with high sensitivity, CdSe/ZnS core/shell QDs were synthesized from the precursors such as CdO and zinc stearate with the lower toxicity than pyrotic precursors. The QD-nanobeads were characterized by transmission electron microscopy, FL microscopy, UV-Vis and PL spectroscopy, respectively.

Prediction of Mechanical Behaviors of Bio-mechanical Materials (생체공학용 척추경 나사의 기계적 거동 예측)

  • Park, Joon-Sik;Choi, Jin Hwa;Cho, Myeong-Woo;Choi, Gil-Woon
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.3 no.1
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    • pp.72-78
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    • 2004
  • In this paper, mechanical behaviors of developed pedicle screw system, made of bio-mechanical materials(Ti-6Al-4V, Grade 5), ale predicted using FEM analysis. As a first step, morphologic construction of normal Korean spines and surgical operation convenience are considered to design optimum pedicle screw system. In this step, various design variables are considered as design parameters to develop optimized models. As a next step, tension and bending tests are performed to improve the structural performance of the developed system using finite element method. In this step, required Static compression and bending test specifications by ASTM F-04 25 04 01 are applied to understand the bio-mechanical behaviors of the designed spinal implant system under various load types. As the results of this research, it is possible to develop efficient pedicle screw system, having enough rigidity and fixation to stand any spinal damage under allowable stress conditions.

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Control of Glass Infiltration at the Al2O3/Glass/Al2O3 Interface

  • Jo, Tae-Jin;Yeo, Dong-Hun;Shin, Hyo-Soon;Hong, Youn-Woo;Cho, Yong-Soo
    • Transactions on Electrical and Electronic Materials
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    • v.12 no.1
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    • pp.32-34
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    • 2011
  • A zero-shrinkage sintering process in which the shrinkage of the x-y axis is controlled to be zero is in great demand due to the high integration trend in ceramic modules. Among the zero-shrinkage sintering processes available, the glass infiltration method proposed in the preliminary study with an $Al_2O_3/Glass/Al_2O_3$ structure is one promising method. However, problems exist in regard to the glass infiltration method, including partially incomplete joining between $Al_2O_3$ and glass layers due to the precipitate of Ti-Pb rich phase during the sintering process. Therefore, we wish to solve the de-lamination problems and suggest a mechanism for delamination and the solutions in the zero-shrinkage low temperature co-fired ceramic (LTCC) layers. The de-lamination problems diminished using the Pb-BSi-O glass without $TiO_2$ in Pb-B-Ti-Si-O glass and produced a very dense zero-shrinkage LTCC.

Growth Characteristics of Polyporales Mushrooms for the Mycelial Mat Formation

  • Bae, Bin;Kim, Minseek;Kim, Sinil;Ro, Hyeon-Su
    • Mycobiology
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    • v.49 no.3
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    • pp.280-284
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    • 2021
  • Mushroom strains of Polyporales from the genera Coriolus, Trametes, Pycnoporus, Ganoderma, and Formitella were explored in terms of mycelial growth characteristics for the application of mushroom mycelia as alternative sources of materials replacing fossil fuel-based materials. Among the 64 strains of Polyporales, G. lucidum LBS5496GL was selected as the best candidate because it showed fast mycelial growth with high mycelial strength in both the sawdust-based solid medium and the potato dextrose liquid plate medium. Some of the Polyporales in this study have shown good mycelial growth, however, they mostly formed mycelial mat of weak physical strength. The higher physical strength of mycelial mat by G. lucidum LBS5496GL was attributed to its thick hyphae with the diameter of 13 mm as revealed by scanning electron microscopic analysis whereas the hyphae of others exhibited less than 2 mm. Glycerol and skim milk supported the best mycelial growth of LBS5496GL as a carbon and a nitrogen source, respectively.

A Study on Promotion of Domestic Timber Utilization According to Dwelling Type Comparison of Between Korea and Japan (한일 주거형태 비교에 의한 국산재 이용 증진 방안 고찰)

  • Yeon, Jung-Youn;Pi, Duck-Won;Kang, Seog-Goo
    • Journal of the Korea Furniture Society
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    • v.24 no.1
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    • pp.51-59
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    • 2013
  • In this study, a dwelling type of Korea and Japan was compared, and consumption rate of domestic timber and its usage was also investigated. In Korea, dwelling type of apartment which constructed by iron and steel-concrete is main shared, but a detached house which is shared at 60% of dwelling type of Japan is mainly constructed by timber. And the rate of the consumption of domestic wood in Japan is 73%. In Japan, there is an effort to substitute imported wood to domestic timber through the promotion of using of domestic timber. Whereas the needs on using of domestic timber gradually emerged. So, the legal about sustainable use of wood is approved by the National Assembly on May 2012. There is not active movement in the aspect of using of domestic timber yet. These causes to the geographical and environmental characteristics, but industry, policy, and the difference of recognize on domestic timber utilization is thought to do greater influence. Hence, it is recommended to make a portfolio of both balanced domestic timber usage and the change of awareness of people by referring to the example of Japan.

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The Effect of Extraction Conditions and Film Side on the Molecular Conformation of Silk Sericin Film

  • Jo, Yoon Nam;Bae, Do Gyu;Um, In Chul
    • International Journal of Industrial Entomology and Biomaterials
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    • v.26 no.2
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    • pp.113-118
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    • 2013
  • In this study, silk sericin films were prepared using different extraction methods, and the molecular conformation of sericin was examined using Fourier-transform infrared spectroscopy with attenuated total reflection geometry. Additionally, the effect of the film side (air-facing side or plate-facing side) on the molecular conformation of the sericin films was investigated. Interestingly, the molecular conformation of the sericin film depended on the film side. The molecular conformation of air-facing side of the sericin film was significantly influenced by extraction solution and time. The ${\beta}$-sheet crystallization and the crystallinity index of the sericin film markedly increased with an increase in the extraction time in hot water. The order of the crystallinity indices for the sericin films obtained with different extraction solutions was as follows: citric acid solution > urea solution >> hot water. In contrast, no remarkable differences were observed in the molecular conformation of the plate-facing side of the sericin film after extraction in hot water for different time periods. Urea and citric acid solution extractions showed remarkably higher crystallinity indices for sericin than those obtained after hot water extraction. However, no significant differences were observed in the crystallinity index of sericin between urea and citric acid solution extraction in plate-facing side of the film.

FSP Mesurement of Heat-treated Hardwoods Using Volumetric Swelling Method (부피팽창률법을 이용한 활엽수 열처리 목재의 섬유포화점 측정)

  • Lee, Seung-Jin;Kang, Seog-Goo;Kang, Chun-Won;Kang, Ho-Yang
    • Journal of the Korea Furniture Society
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    • v.23 no.2
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    • pp.163-168
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    • 2012
  • Specimens of seven hardwood species were heat-treated at three temperature levels of 170, 190 and $210^{\circ}C$. Their FSP's were measured by the volumetric swelling method and compared with the control's. Within a species the FSP decreases as the temperature of heat treatment increases. The FSP's of the controls range from 26.1 to 29.6%, while those of the specimens heat-treated at $210^{\circ}C$ from 16.9 to 21.8%. There were no difference of basic density between the heat-treated and control specimens. The color indexes of ash and beech specimens were measured using a colorimeter. It was revealed that the temperature of heat treatment affected on the color more than the treatment time.

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