• Title/Summary/Keyword: bias effect

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Systematic Review of Bee Venom Therapy for Traumatic Injury (임상에서 흔히 접하는 외상성 손상에 대한 봉독약침요법의 체계적 문헌고찰)

  • Lee, Jae-Eun;Lee, Chi-Ho;Lee, Eun-Jung;Lee, Jung-Min;Oh, Min-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.26 no.3
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    • pp.67-77
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    • 2016
  • Objectives To evaluate the evidence supporting the effectiveness of Bee Venom therapy for traumatic injury. Methods We conducted search across 3 electronic databases (Pubmed, CAJ and Oasis) to find clinical trials that used Bee Venom therapy as treatment for traumatic injury. The methodological quality of RCTs (Randomized controlled clinical trials) were assessed using the Cochrane Risk of Bias (RoB) tool, while NRCTs (Non-Randomized controlled clinical trials) were assessed using the Cochrane Risk of Bias Assessment tool for Non-randomized Study (RoBANS) tool. Results Among 87 articles that were searched, 10 RCTs and 19 NRCTs were finally selected. Among 19 selected studies, all studies showed that Bee Venom therapy has significant effect on traumatic injury. Conclusions Our systematic review found encouraging but limited evidence of Bee Venom therapy for traumatic injury. We recommend clinical trials which compare the effectiveness of Bee Venom therapy with other pharmacopuncture therapies to clarify the effectiveness of Bee Venom therapy from other pharmacopuncture therapies.

Dynamic Magnetostriction Characteristics of an Fe-Based Nanocrystalline FeCuNbSiB Alloy

  • Chen, Lei;Li, Ping;Wen, Yumei
    • Journal of Magnetics
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    • v.16 no.3
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    • pp.211-215
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    • 2011
  • The dynamic magnetostriction characteristics of an Fe-based nanocrystalline FeCuNbSiB alloy are investigated as a function of the dc bias magnetic field. The experimental results show that the piezomagnetic coefficient of FeCuNbSiB is about 2.1 times higher than that of Terfenol-D at the low dc magnetic bias $H_{dc}$ = 46 Oe. Moreover, FeCuNbSiB has a large resonant dynamic strain coefficient at quite low Hdc due to a high mechanical quality factor, which is 3-5 times greater than that of Terfenol-D at the same low $H_{dc}$. Based on such magnetostriction characteristics, we fabricate a new type of transducer with FeCuNbSiB/PZT-8/FeCuNbSiB. Its maximum resonant magnetoelectric voltage coefficient achieves ~10 V/Oe. The ME output power reaches 331.8 ${\mu}W$ at an optimum load resistance of 7 $k{\Omega}$ under 0.4 Oe ac magnetic field, which is 50 times higher than that of the previous ultrasonic-horn-substrate composite transducer and it decreases the size by nearly 86%. The performance indicate that the FeCuNbSiB/PZT-8/FeCuNbSiB transducer is promising for application in highly efficient magnetoelectric energy conversion.

The Effect of Managerial Ability on Analysts' Earnings Forecast (경영자 능력이 재무분석가 이익예측 정보에 미치는 영향)

  • Park, Bo-Young
    • Management & Information Systems Review
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    • v.35 no.4
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    • pp.213-227
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    • 2016
  • This study examines the effects of managerial ability on information asymmetry. We use analyst forecast errors as a proxy for information asymmetry, because analysts are referred to as efficient users using firm-level data. The sample consists of 2,246 non-banking firm-years listed in Korea Stock Exchange(KOSPI) during the period 2000 to 2013. We measure managerial ability using DEA(Data Envelopment Analysis) following Demerjian et al.(2012). Using those measures, we examines the effects of managerial ability on analysts' earnings forecast errors and analysts' earnings forecast bias. The results of this study are as follows. First, we find that managerial ability are positively associated with analysts' earnings forecast accuracy. Second, we show that the firms with higher managerial ability tend to have lower the optimistic errors in analysts' earnings forecasts. This study could be useful for outside stakeholders to understand the importance of managerial ability.

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Rotating Arm Test for Assessment of an Underwater Hybrid Navigation System for a Semi-Autonomous Underwater Vehicle (반자율무인잠수정의 수중 복합항법 시스템 성능평가를 위한 회전팔 시험)

  • Lee, Chong-Moo;Lee, Pan-Mook;Kim, Sea-Moon;Hong, Seok-Won;Seo, Jae-Won;Seong, Woo-Jae
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2003.05a
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    • pp.141-148
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    • 2003
  • This paper presents a rotating ann test for assessment of an underwater hybrid navigation system for a semi-autonomous underwater vehicle. The navigation system consists of an inertial measurement unit (IMU), an ultra-short baseline (USBL) acoustic navigation sensor and a doppler velocity log (DVL) accompanying a magnetic compass. The errors of inertial measurement units increase with time due to the bias errors of gyros and accelerometers. A navigational system model is derived to include the error model of the USBL acoustic navigation sensor and the scale effect and bias errors of the DVL, of which the state equation composed of the navigation states and sensor parameters is 25 in the order. The conventional extended Kalman filter was used to propagate the error covariance, update the measurement errors and correct the state equation when the measurements are available. The rotating ann tests are conducted in the Ocean Engineering Basin of KRISO, KORDI to generate circular motion in laboratory, where the USBL system was absent in the basin. The hybrid underwater navigation system shows good tracking performance against the circular planar motion. Additionally this paper checked the effects of the sampling ratio of the navigation system and the possibility of the dead reckoning with the DVL and the magnetic compass to estimate the position of the vehicle.

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Underwater Hybrid Navigation System Based on an Inertial Sensor and a Doppler Velocity Log Using Indirect Feedback Kalman Filter (간접 되먹임 필터를 이용한 관성센서 및 초음파 속도센서 기반의 수중 복합항법 시스템)

  • Lee, Chong-Moo;Lee, Pan-Mook;Seong, Woo-Jae
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2003.05a
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    • pp.149-156
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    • 2003
  • This paper presents an underwater hybrid navigation system for a semi-autonomous underwater vehicle (SAUV). The navigation system consists of an inertial measurement unit (IMU), an ultra-short baseline (USBL) acoustic navigation sensor and a doppler velocity log (DVL) accompanying a magnetic compass. The errors of inertial measurement units increase with time due to the bias errors of gyros and accelerometers. A navigational system model is derived to include the error model of the USBL acoustic navigation sensor and the scale effect and bias errors of the DVL, of which the state equation composed of the navigation states and sensor parameters is 25 in the order. The conventional extended Kalman filter was used to propagate the error covariance, update the measurement errors and correct the state equation when the measurements are available. Simulation was performed with the 6-d.o.f. equations of motion of SAUV in a lawn-mowing survey mode. The hybrid underwater navigation system shows good tracking performance by updating the error covariance and correcting the system's states with the measurement errors from a DVL, a magnetic compass and a depth senor. The error of the estimated position still slowly drifts in horizontal plane about 3.5m for 500 seconds, which could be eliminated with the help of additional USBL information.

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Design and Implementation of Depolarized FOG based on Digital Signal Processing (All DSP 기반의 비편광 FOG 설계 및 제작)

  • Yoon, Yeong-Gyoo;Kim, Jae-Hyung;Lee, Sang-Hyuk
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.8
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    • pp.1776-1782
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    • 2010
  • The interferometric fiber optic gyroscopes (FOGs) are well known as sensors of rotation, which are based on Sagnac effect, and have been under development for a number of years to meet a wide range of performance requirements. This paper describes the development of open-loop FOG and digital signal processing techniques implemented on FPGA. Our primary goal was to obtain intermediate accuracy (pointing grade) with a good bias stability (0.22deg) and scale factor stability, extremely low angle random walk (0.07deg) and significant cost savings by using a single mode fiber. A secondary goal is to design all digital FOG signal processing algorithms with which the SNR at the digital demodulator output is enhanced substantially due to processing gain. The Cascaded integrator bomb(CIC) type of decimation filter only requires adders and shift registers, low cost processors which has low computing power still can used in this all digital FOG processor.

Study on the Electrical Characteristics of Solution-processed ZrInZnO Thin-film Transistors (액상공정으로 제작된 ZrInZnO 박막 트랜지스터의 전기적 특성에 관한 연구)

  • Jeong, Tae-Hoon;Kim, Si-Joon;Yoon, Doo-Hyun;Jeong, Woong-Hee;Kim, Dong-Lim;Lim, Hyun-Soo;Kim, Hyun-Jae
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.24 no.6
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    • pp.458-462
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    • 2011
  • Soution-processed ZrInZnO (ZIZO) thin-film transistors (TFTs) with varying Zr content were fabricated. The ZIZO TFT (Zr=20 at. %/Zn) has an optimal performance with the saturation field effect mobility of 0.77 $cm^2/Vs$, the threshold voltage (Vth) of 2.1 V, the on/off ratio of $4.95{\times}10^6$, and subthreshold swing (S.S) of 0.73 V/decade. Using this optimized ZIZO TFT, the positive and negative gate bias stress according to annealing temperature was also investigated. While the Vth shifts dramatically after 1,000 s of both gate bias stresses, variations in the S.S are negligible. It suggests that electrons or holes are tem porarily trapped in the gate insulator, the semiconductor, or the interface between both layers.

The Association between Mast Cell Distribution and Acupoint Specificity: A Comprehensive Review (경혈에서의 비만세포 분포특성에 대한 연구 고찰)

  • Ji, JeongYeon;Bae, Sun-Jeong;Oh, Ju-Young;Jung, Hyuk-Sang;Park, Hi-Joon
    • Korean Journal of Acupuncture
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    • v.37 no.3
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    • pp.145-158
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    • 2020
  • Objectives : Mast cells, the multifunctional immune cells which can be activated by various stimulations, have been in the limelight recently at the fields of acupuncture research. This study aimed to investigate the association between the distribution of mast cell and acupoint specificity. We focused on the characteristics of mast cell distribution of acupoints in normal, pathologically sensitized, and acupoint-stimulated state. Methods : Literature searches were performed on PubMed and EMBASE for dates ranging to February 2019, by using terms "acupuncture", "moxibustion", "acupoint", "mast cell". Finally, 18 papers were collected by inclusion and exclusion criteria. To assess the quality of included studies, modified SYRCLE's risk of bias tool for animal studies was used. Results : Overall, the studies showed that the number of the mast cells was higher in acupoints than non-acupoints. After pathological sensitization, increasing tendency towards the mast cell number was reported in acupoints. The increase of mast cells was also observed after acupuncture or moxibustion. However, when the acupoint stimulation was repeated for several days in pathological models, the results did not show consistent tendency. In quality assessments, most of the studies showed unclear risk of bias. Conclusions : The studies showed a consistent trend about the association with mast cell distribution and acupoint specificity. However, we could not certainly affirm the relationship due to insufficient qualities of included studies. Not only the distribution but also the functions should be considered in further researches to identify the relationship between mast cells and acupuncture effect.

Design of DSP based Depolarized Fiber Optic Gyroscope (DSP 기반의 비편광 광자이로스코프 설계)

  • Yoon, Yeong-gyoo;Joo, Min-sik;Kim, Yeong-jin;Kim, Jae-hyoung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.153-156
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    • 2009
  • The interferometric fiber optic gyroscopes (FOGs) are well known as sensors of rotation, which are based on Sagnac effect, and have been under development for a number of years to meet a wide range of performance requirements. This paper describes the development of open-loop FOG and digital signal processing techniques implemented on FPGA. Our primary goal was to obtain intermediate accuracy (pointing grade) with a good bias stability ($0.22^{\circ}/hr$) and scale factor stability, extremely low angle random walk ($0.07^{\circ}/\sqrt{hr}$) and significant cost savings by using a single mode fiber. A secondary goal is to design all digital FOG signal processing algorithms with which the SNR at the digital demodulator output is enhanced substantially due to processing gain. The CIC type of decimation block only requires adders and shift registers, low cost processors which has low computing power still can used in this all digital FOG processor.

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The Effects of Balloon-Guide Catheters on Outcomes after Mechanical Thrombectomy in Acute Ischemic Strokes : A Meta-Analysis

  • Ahn, Jun Hyong;Cho, Steve S.;Kim, Sung-Eun;Kim, Heung Cheol;Jeon, Jin Pyeong
    • Journal of Korean Neurosurgical Society
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    • v.62 no.4
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    • pp.389-397
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    • 2019
  • Objective : Mechanical thrombectomies with balloon-guide catheters (BGC) are thought to improve successful recanalization rates and to decrease the incidence of distal emboli compared to thrombectomies without BGC. We aimed to assess the effects of BGC on the outcomes of mechanical thrombectomy in acute ischemic strokes. Methods : Studies from PubMed, EMBASE, and the Cochrane library database from January 2010 to February 2018 were reviewed. Random effect model for meta-analysis was used. Analyses such as meta-regression and the "trim-and-fill" method were additionally carried out. Results : A total of seven articles involving 2223 patients were analyzed. Mechanical thrombectomy with BGC was associated with higher rates of successful recanalization (odds ratio [OR], 1.632; 95% confidence interval [CI], 1.293-2.059). BGC did not significantly decrease distal emboli, both before (OR, 0.404; 95% CI, 0.108-1.505) and after correcting for bias (adjusted OR, 1.165; 95% CI, 0.310-4.382). Good outcomes were observed more frequently in the BGC group (OR, 1.886; 95% CI, 1.564-2.273). Symptomatic intracranial hemorrhage and mortality did not differ significantly with BGC use. Conclusion : Our meta-analysis demonstrates that BGC enhance recanalization rates. However, BGC use did not decrease distal emboli after mechanical thrombectomies. This should be interpreted with caution due to possible publication bias and heterogeneity. Additional meta-analyses based on individual patient data are needed to clarify the role of BGC in mechanical thrombectomies.