• Title/Summary/Keyword: bias effect

Search Result 1,482, Processing Time 0.03 seconds

Relationship between Antihypertension Medication Adherence, Medical Utilizations, and Medical Expenditure Among Patients with Hypertension (한국의료패널을 활용한 고혈압환자의 복약순응도가 의료이용 및 의료비 지출에 미치는 영향 분석)

  • Kim, SeongOk;Jang, Sunmee
    • YAKHAK HOEJI
    • /
    • v.57 no.5
    • /
    • pp.369-375
    • /
    • 2013
  • Objective: Using the Korean Health Panel data (KHP) of 2008 and 2009, this paper analyzed the effect of antihypertension medication adherence on the changes in medical service utilization and medical expenditure in the next year. Method: Through a face-to-face interview survey, KHP has provided an extensive data on demographic characteristics, medical utilizations behavior, medical expenditure and health behaviors of the targeted households and their members since 2008. KHP is recognized as highly accurate regarding medical expenditure in that it makes the target households to record 'Health diary' whenever they use healthcare service, which could minimize their cognitive bias or memory distortion. The 2010 KHP data was based on the interview from 6,432 households and 19,697 household members. Two part model was used to explore the effects of medication adherence on medical use (logistic regression analysis) and medical expenditures (OLS). Result: Our study result demonstrated that the 74.7% of the patients who strictly adhere to their medication in both years, in 2008 and in 2009, were likely to use inpatient service in 2010. This shows the noncompliant patients were in fact use emergency service less than the compliant patients. Conclusion: Based on our analysis, this paper concludes that the high medication adherence of hypertensive patients could contribute to reduce the emergency service use. Therefore it is highly recommendable for the Korean government and the insurer, NHIS, to actively invest in developing education and promotion program to improve medication adherence among hypertensive patients.

Electrical Property Changes of $\textrm{NO}_X$ Sensitive $\textrm{WO}_3$ Thin Films as Applied DC Voltages on 8YSZ Substrate (8YSZ 기판에 증착한 $\textrm{WO}_3$ 박막의 DC 전압에 따른 $\textrm{NO}_X$ 감지특성)

  • 전춘배;박기철
    • Journal of the Korean Institute of Telematics and Electronics T
    • /
    • v.36T no.1
    • /
    • pp.8-12
    • /
    • 1999
  • $\textrm{WO}_3$ semiconductive film, which is known to have a sensitivity on $\textrm{NO}_X$ gas was prepared on 8YSZ (8% Yttria stabilized $\textrm{ZrO}_2$) ionic conductor substrate that has oxygen ion pumping effect. Microstructure and electrical properity, especially $\textrm{NO}_X$ sensitivity as a function of DC voltage applied to 8YSZ substrate was examined. When the $\textrm{WO}_3$ film was annealed, it showed amorphous structure, while crystallization was occurred at $600^{\circ}$C revealing orthorhombic phase of $\textrm{WO}_3$. As the annealing temperature increases, (111) and (001) peaks of $\textrm{WO}_3$ film was enhanced. At $400^{\circ}C$ when DC voltage was applied, comparing with no DC bias, more stable and large response characteristics was showed, and the best sensitivity was observed at 2V. Recovery characteristics of NO gas was much better that that of $\textrm{NO}_2$ gas.

  • PDF

Prognostic Value of Vascular Endothelial Growth Factor Expression in Patients with Prostate Cancer: a Systematic Review with Meta-analysis

  • Wang, Kai;Peng, Hong-Ling;Li, Long-Kun
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.11
    • /
    • pp.5665-5669
    • /
    • 2012
  • Background: The vascular endothelial growth factor (VEGF) mediates vasculogenesis and angiogenesis through promoting endothelial cell growth, migration and mitosis, and has involvement in cancer pathogenesis, progression and metastasis. However, the prognostic value of VEGF in patients with prostate cancer remains controversial. Objectives: The aim of our study was to evaluate the prognostic value of VEGF in prostate cancer, and summarise the results of related research on VEGF. Methods: In accordance with an established search strategy, 11 studies with 1,529 patients were included in our meta-analysis. The correlation of VEGF-expression with overall survival and progression-free survival was evaluated by hazard ratio, either given or calculated. Results: The studies were categorized by introduction of the author, demographic data in each study, prostate cancer-relatived information, VEGF cut-off value, VEGF subtype, methods of hazard ratio (HR) estimation and its 95% confidence interval (CI). High VEGF-expression in prostate cancer is a poor prognostic factor with statistical significance for OS (HR=2.32, 95%CI: 1.40-3.24). However, high VEGF-expression showed no effect on poor PFS (HR=1.30, 95%CI: 0.88-1.72). Using Begg's, Egger's test and funnel plots, we confirmed lack of publication bias in our analysis. Conclusion: VEGF might be regarded as a prognostic maker for prostate cancer, as supported by our meta-analysis. To achieve a more definitive conclusion enabling the clinical use of VEGF in prostate cancer, we need more high-quality interventional original studies following agreed research approaches or standards.

Effect of Heated Red Bean Pillow Application for College Women with Dysmenorrhea

  • Kim, Jeung-Im
    • Women's Health Nursing
    • /
    • v.19 no.2
    • /
    • pp.67-74
    • /
    • 2013
  • Purpose: Dysmenorrhea is a menstrual condition characterized by severe and frequent cramps and pain. Effective treatment methods for dysmenorrhea are not yet fully understood. This research compares the effects of pain killers and heated red bean pillows. Methods: Data were got on demographic data, menstrual cycle status, and activities of daily living (ADLs) limitations, dysmenorrhea severity and menstrual pain scores. Following a 10% drop-out rate, 44 young women satisfied the inclusion criteria. To prevent any bias, the experimental and control groups were selected from different campuses. We used two sizes of red bean pillows: $13{\times}11.5cm$, weighing 400g; and $15{\times}18cm$, weighing 220g. For analysis, we used IBM SPSS statistics 19.0. Results: Ninety-nine point seven percentage of total subjects reported moderate to severe dysmenorrhea and 63.6% reported as moderate to severe daily activities limitations. The mean pain score with visual analogue scale was $80.2{\pm}9.42$ of 100 and 86.4% used pain killers to alleviate menstrual discomfort in all the subjects. In both groups, all three variables showed significant improvement and the Moos's Menstrual Distress Questionnaire (MDQ) scores changed significantly between menstrual and post-menstrual time point at within groups and not significantly different at premenstrual and menstrual time point at between groups. However, the MDQ score was significantly higher in experimental group than control group at post-menstruation time point and the degree of satisfaction was higher in the control group. Conclusion: This research shows that red-bean pillows on the abdomen are effective in assisting the ADL and diminishing pain severity. With regard to its safety the study indicates it can be a convenient and safe option for female students with menstrual discomfort in schoolas a non-pharmacological self-help.

Evaluation of Coastal Sediment Budget on East Coast Maeongbang Beach by Wave Changes (파랑 변화에 따른 동해안 맹방 해수욕장 연안 표사수지 파악)

  • Kim, Gweon-Su;Ryu, Ha-Sang;Kim, Sang-Hoon
    • Journal of Ocean Engineering and Technology
    • /
    • v.33 no.6
    • /
    • pp.564-572
    • /
    • 2019
  • Numerical simulation of the sediment by the Delft3d model was conducted to examine the changes in the sediment budget transport caused by long-term wave changes at the Maengbang beach. Representative waves were generated with input reduction tools using NOAA NCEP wave data for about 40 years, i.e., from January 1979 to May 2019. To determine the adequacy of the model, wave and depth changes were compared and verified using wave and depth data observed for about 23 months beginning in March 2017. As a result of the error analysis, the bias was 0.05 and the root mean square error was 0.23, which indicated that the numerical wave results were satisfactory. Also, the observed change in depth and numerical result were similar. In addition, to examine the effect due to long-term changes in the waves, the NOAA wave data classified into each of the representative wave grades, and then the annual trend of the representative wave was analyzed. After deciding the weight of each wave class considering the changed wave environment in 2100, the amounts of sedimentation, deposition, and the sediment transport budget were reviewed for the same period. The results indicated that the sedimentation pattern did not change significantly compared to the current state, and the amount of the local sediment budget shown in the present state was slightly less. And there has been a local increase in the number of sediment budget transport, but there is no significant difference in the net and amount of sediment movements.

Outcomes of comprehensive fixed appliance orthodontic treatment: A systematic review with meta-analysis and methodological overview

  • Papageorgiou, Spyridon N.;Hochli, Damian;Eliades, Theodore
    • The korean journal of orthodontics
    • /
    • v.47 no.6
    • /
    • pp.401-413
    • /
    • 2017
  • Objective: The aim of this systematic review was to assess the occlusal outcome and duration of fixed orthodontic therapy from clinical trials in humans with the Objective Grading System (OGS) proposed by the American Board of Orthodontics. Methods: Nine databases were searched up to October 2016 for prospective/retrospective clinical trials assessing the outcomes of orthodontic therapy with fixed appliances. After duplicate study selection, data extraction, and risk of bias assessment according to the Cochrane guidelines, random-effects meta-analyses of the mean OGS score and treatment duration were performed and 95% confidence intervals (CIs) were calculated. Results: A total of 34 relevant clinical trials including 6,207 patients (40% male, 60% female; average age, 18.4 years) were identified. The average OGS score after treatment was 27.9 points (95% CI, 25.3-30.6 points), while the average treatment duration was 24.9 months (95% CI, 24.6-25.1 months). There was no significant association between occlusal outcome and treatment duration, while considerable heterogeneity was identified. In addition, orthodontic treatment involving extraction of four premolars appeared to have an important effect on both outcomes and duration of treatment. Finally, only 10 (39%) of the identified studies matched compared groups by initial malocclusion severity, although meta-epidemiological evidence suggested that matching may have significantly influenced their results. Conclusions: The findings from this systematic review suggest that the occlusal outcomes of fixed appliance treatment vary considerably, with no significant association between treatment outcomes and duration. Prospective matched clinical studies that use the OGS tool are needed to compare the effectiveness of orthodontic appliances.

Electroacupuncture for Treatment of Primary Dysmenorrhea: Systematic Review of Randomized Controlled Trials (원발성 월경통의 전침 치료 연구에 관한 체계적 문헌 고찰)

  • Park, Nam-Chun;Kang, Na-Hoon;Yoo, Eun-Sil;Lee, Jin-Wook;Yoon, Jun-Geol;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bok;Hwang, Deok-Sang
    • The Journal of Korean Obstetrics and Gynecology
    • /
    • v.30 no.2
    • /
    • pp.81-92
    • /
    • 2017
  • Objectives: This review aims to report the efficacy and safety of electroacupuncture in the treatment of primary dysmenorrhea. Methods: We searched for randomized controlled studies (RCTs) using electroacupuncture on primary dysmenorrhea up to Dec 2016. The following databases were searched : OASIS, PubMED, EMBASE, CENTRAL. The results of the studies were analyzed and the risk of bias was assessed. Results: Five studies were included in this review. In most studies, the effect of electroacupuncture at Sameumgyo (SP6) was better than that of electroacupuncture at Hyeonjong (GB39), nonacupoint and no intervention about Visual analog scale (VAS), Verbal rating scale (VRS) and Retrospective symptom scale (RSS). But there were no significant effects on Resistance Index (RI) and S/D ratio (the ratio between peak systolic to end-diastolic flow velocity in uterine arteries). Serous adverse events were not reported. Conclusions: This review shows that electroacupuncture is effective on primary dysmenorrhea with no serious adverse events.

Improvement Performance of Graphene-MoS2 Barristor treated by 3-aminopropyltriethoxysilane (APTES)

  • O, Ae-Ri;Sim, Jae-U;Park, Jin-Hong
    • Proceedings of the Korean Vacuum Society Conference
    • /
    • 2016.02a
    • /
    • pp.291.1-291.1
    • /
    • 2016
  • Graphene by one of the two-dimensional (2D) materials has been focused on electronic applications due to its ultrahigh carrier mobility, outstanding thermal conductivity and superior optical properties. Although graphene has many remarkable properties, graphene devices have low on/off current ratio due to its zero bandgap. Despite considerable efforts to open its bandgap, it's hard to obtain appropriate improvements. To solve this problem, heterojunction barristor was proposed based on graphene. Mostly, this heterojunction barristor is made by transition metal dichalcogenides (TMDs), such as molybdenum disulfide ($MoS_2$) and tungsten diselenide ($WSe_2$), which have extremely thickness scalability of TMDs. The heterojunction barristor has the advantage of controlling graphene's Fermi level by applying gate bias, resulting in barrier height modulation between graphene interface and semiconductor. However, charged impurities between graphene and $SiO_2$ cause unexpected p-type doping of graphene. The graphene's Fermi level modulation is expected to be reduced due to this p-doping effect. Charged impurities make carrier mobility in graphene reduced and modulation of graphene's Fermi level limited. In this paper, we investigated theoretically and experimentally a relevance between graphene's Fermi level and p-type doping. Theoretically, when Fermi level is placed at the Dirac point, larger graphene's Fermi level modulation was calculated between -20 V and +20 V of $V_{GS}$. On the contrary, graphene's Fermi level modulation was 0.11 eV when Fermi level is far away from the Dirac point in the same range. Then, we produced two types heterojunction barristors which made by p-type doped graphene and graphene treated 2.4% APTES, respectively. On/off current ratio (32-fold) of graphene treated 2.4% APTES was improved in comparison with p-type doped graphene.

  • PDF

Development of Modern Dolbok Design Based on Traditional Hanbok Style (전통한복 양식에 기반한 현대의 돌복 디자인 개발)

  • Lee, Ji Won;Song, Jung A
    • Fashion & Textile Research Journal
    • /
    • v.17 no.5
    • /
    • pp.793-799
    • /
    • 2015
  • Hanboks have evolved throughout time; for example, the curved Barae has changed into a more modern and sophisticated straight one. The development of staining techniques has increased color selections with more luxurious designs. I suggested a design of Dolbok that considers functionality, practicality and economic feasibility through a comparison of past and present designs. I suggested a fusion Hanbok based on a traditional Dolbok for baby boys and girls. An abundance of cheap resources has decreased the tradition of hand down clothes; therefore, I created functional and economic methods to adjust a Hanbok for kids to wear a long time. First, I made it possible to adjust the length of a skirt by a slip stitch (or catch) stitch with a Seurandan (ornate lower band) and placed the button on shoulder part of the skirt for baby girls. The width of skirt is designed for a 4 year old instead of 1 year old to adjust the size and compensate for growing kids; however, the clothes still look stylish despite the overlapped area. Second, I made a baby boy's vest with a belt that follows traditional methods that were comfortable for width variation. Third, I made Geodeulji (sleeve-ends trimmed with wide bias) that enabled long or short sleeves. Geodeulji made with a variety of fabric colors will enhance the decorative effect. Fourth, I made the width of clothes adjustable by putting Korum (tie) ON Jeogori for baby boys and girls. There are many studies on Hanboks but few reports on modern Dolbok. I believe that designers should further study fusion Hanboks within framework of traditional Hanbok designs to increase comfort and appeal.

Modeling Subway Accessibility in Seoul Public Transport System Reform (수도권 대중교통체계 개편 전.후 지하철 이용자의 접근성 변화 모형구축)

  • Kim, Chan-Sung;Seong, Hong-Mo;Shin, Seong-Il
    • Journal of Korean Society of Transportation
    • /
    • v.23 no.8 s.86
    • /
    • pp.101-111
    • /
    • 2005
  • Various urban transport policies have an effect on urban transit riderships and accessibility. This study reports variations of metropolitan subway travel patterns affected by an enormous change in bus routes and transfer discount fare policy between subway and bus mode conducted by Seoul city in July 1st of 2004. In an effort to see the difference between the before and the after policies, two data sets are prepared. Firstly, on a daily bassis. an origin-destination trip table of May of 2004 is used. Secondly, on a daily bassis, an origin-destination trip table of August-September of 2004 is used as a counter measure. Even if seasonal variation was not considered, Seoul metropolitan area have experienced increasing riderships and accessibility. Finally, the effects of accessibility in spatial interaction model by rall service changes such as random shocks were scrutinized and interpreted in detail.