• Title/Summary/Keyword: beta test

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Ti-Nb계 합금의 세포독성에 관한 연구 (A study on cytotoxicity of Ti-Nb alloys)

  • 박효병
    • 대한치과기공학회지
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    • 제25권1호
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    • pp.89-94
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    • 2003
  • The use of titanium alloys as biomaterials is increasing due to their superior biocompatibility and enhanced corrosion resistance compared to conventional stainless steels and cobalt-based alloys. Ti-6Al-4V ($\alpha+\beta$type) alloy instead of pure titanium ($\alpha$type) is being widely used as biomaterials has some characteristics such as high fatigue strength, tensile strength and corrosion resistance. It also has similar characteristics to Ti in inducing bony ingrowth. But it has been reported recently that the vanadium element expresses cytotoxicity and carcinogenicity and the aluminium element is related with dementia of Alzheimer type and neurotoxicity. In order to overcome their detrimental effects, $\beta$-phase stabilizer Nb was chosen in the present study. CP-Ti(ASTM grade 2), Ti-3wt.%Nb($\alpha$type), Ti-20wt.%Nb ($\alpha+\beta$type) and Ti-40 wt.%Nb($\beta$type) alloys were melted by vacuum arc furnace. Biocompatibility of Ti-Nb alloys was evaluated by cytotoxicity test. The results can be summarized as follows: 1. For the cytotoxicity test, Ti-Nb alloys showed excellent biocompatibility compared to CP-Ti(ASTM grade 2), 316L STS and Co-Cr alloys.

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간호대학생의 회복탄력성, 대처 및 정신건강이 소진에 미치는 영향 (Effect of Resilience, Coping, and Mental Health on Burnout of Student Nurses)

  • 조헌하;강정미
    • Child Health Nursing Research
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    • 제24권2호
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    • pp.199-207
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    • 2018
  • Purpose: The purpose of this study was to investigate resilience, coping, and mental health in relation to burnout and to identify factors influencing burnout in student nurses. Methods: A descriptive correlational study was conducted. The participants were 241 student nurses from 2 universities in B city. Data were analyzed using the t-test, analysis of variance, the Pearson correlation coefficient, the $Scheff{\acute{e}}$ test, and multiple regression analysis. Results: The mean score for burnout in student nurses was 3.01 out of 5 points. Burnout explained 29.2% of the variance in satisfaction with college life (${\beta}=-.367$, p<.001), coping (${\beta}=.293$, p<.001), mental health (${\beta}=.228$, p=.011), and training hospital (${\beta}=-.198$, p=.026). Conclusion: The results of our research suggest that satisfaction with college life is an important variable affecting burnout student nurses. Therefore, education is needed in order to develop for more effective teaching coping methods and strategies and to reduce burnout with nursing practice.

치과위생사의 소명의식과 감정노동이 재직의도에 미치는 영향 (The effects of dental hygienists' sense of calling and emotional labor on retention intention)

  • 원영순;오한나
    • 한국치위생학회지
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    • 제18권5호
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    • pp.707-716
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    • 2018
  • Objectives: The purpose of this study was to examine factors influencing the retention intention of dental hygienists in clinical practice. Findings will assist in the development of strategies to increase their retention. Methods: A self-reported questionnaire was completed by 261 dental hygienists who work at dental hospitals and clinics in the Jeollabuk-do area. Data were analyzed using descriptive statistics, independent t-test, one-way ANOVA (post-test Duncan), and multiple regressions. Results: The variable that demonstrated the largest influence on the retention intention of dental hygienists was purpose/meaning (${\beta}=0.283$), followed by transcendental calling (${\beta}=0.198$). These factors relate to the sense of calling. The third most influential variable was pay (${\beta}=0.150$). This relates to general characteristics. The fourth most influential factor was the frequency of emotion display (${\beta}=-0.112$), which relates to one of the sub-areas of emotional labor. Conclusions: In order to strengthen the retention intention of dental hygienists, diverse approaches should be implemented, with particular consideration for their sense of calling, emotional labor and pay.

Beta-gamma TiAl 합금의 고온변형거동 (High Temperature Deformation Behavior of Beta-gamma TiAl Alloy)

  • 김지수;김영원;이종수
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2006년도 춘계학술대회 논문집
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    • pp.429-433
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    • 2006
  • High Temperature deformation behavior of newly developed beta-gamma TiAl alloy was investigated in this study. The optimum processing condition was investigated with the aid of Dynamic Materials Model (DMM). Processing maps representing the efficiency of power dissipation for microstructural evolution and instability were constructed utilizing the results of hot compression test at temperatures ranging from $1000^{\circ}C$ to $1200^{\circ}C$ and strain rate ranging from $10^{-4}/s$ to $10^2/s$. The Artificial Neural Network (ANN) simulation was adopted to consider the deformation heating. With the help of processing map and microstructural analysis, the optimum processing condition was presented and the role of $\beta$ phase was also discussed in this study.

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영지버섯 균사체 (Ganoderma lucidum IY009)로부터 추출한 단백다당체의 항암촬성 (Antitumor Activities of the Proteoglycans from the Mycelium of Ganoderma lucidum IY009)

  • 백성진;김용석;용환미;채주병;윤환민;박승국
    • 약학회지
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    • 제45권6호
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    • pp.641-649
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    • 2001
  • In this study, the antitumor activities were investigated using $\beta$-lmmunan, a proteoglycan obtained from cultured mycelia of the IY009 strain of Ganoderma lucidum belonging to basidiomycetes. The result showed the significant effect of cytotoxicity test against murine sarcoma 180 and murine lymphocytic leukemia L1210 using immunized macrophage cultures by $\beta$-lmmunan. When intraperitoneally injected at 40 mg/kg/day daily for 10 days, $\beta$-lmmunan inhibited the growth of sarcoma 180 solid tumor in ICR mice by 88.8% (p<0.05). It was also observed that $\beta$-lmmunan increased life span by 85.2% (p<0.01) after treatment of 100 mg/kg/day in BDF1 mice bearing lymphocytic leukemia L1210. And combination therapy with cisplatin (dosage: 4 mg/kg) increased life span by 140.4% (p<0.05) after treatment of 100 mg/kg/day daily in BDF1 mice bearing lymphocytic leukemia L1210.

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부산 도축장에서 분리된 광범위 베타 락탐 분해효소(Extended-Spectrum ${\beta}$-Lactamase, ESBL)생성 장내세균의 형별분류 (Typing of Extended-Spectrum ${\beta}$-Lactamase (ESBL) Producing Enterobacteriaceae Isolated from Slaughterhouse in Pusan, Korea)

  • 이훈구
    • 미생물학회지
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    • 제42권2호
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    • pp.125-130
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    • 2006
  • 본 연구에서는 도축장과 도축물에서 plasmid 매개성 광범위 ${\beta}$-lactam (extended spectrum ${\beta}$-lactamase) 분해효소를 생성하는 Klebsiella pneumoniae와Escherichia coli가 분리됨으로서 한국에서는 이들 균주가 임상범위를 넘어 자연계까지 확산되었음을 확인하였다. 디스크 확산 시험, 등전점 수치, 접합시험 등을 통하여 돼지의 분변으로부터 최종 10균주의 접합자를 얻었고 이들의 형별결정은 아미노산서열분석과 기준주와 대조등을 BCM Search Laucncher 및 NCBI blast를 통해 이루어졌다. 광범위 ${\beta}$-lactam 유형은 Klebsiella pneumoniae 8균주가 TEM-52형이었고 2균주 Escherichia coli가 SHV-12형이었다. CMY-1형은 본 연구에서 분리되지 않았다.

Protective Effect of Acetylbenzoylaconine Against Gamma-radiation

  • Moon, Philip S.
    • Nuclear Engineering and Technology
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    • 제5권2호
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    • pp.83-86
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    • 1973
  • Acetylbenzoylaconine, 2-aminoethylisothiouronium bromide hydrobromide (AET), $\beta$-mercaptoethylamine HCI (MEA), L-thiazolidine-4-carboxylic acid (thioproline)의 Co-60 감마선에 대한 방어효과를 5-6주된 백색마우스를 이용하여 연구하였다. 백색마우스에 대한 acetylbenzoylaconine의 독성실험 결과 LD$_{50}$은 2.5mg/kg이었다. 위의 4종 실험약제를 백색마우스 복강내에 주사한 후 Co-60 감마선 800 rad를 전신조사하고 30일간 계속 관찰하여 실험군들에 대한 생존계수를 계산하였다. 이 생존계수치로 방사선장해에 대한 방어계수를 계산한 결과 acetylbenzoylaconine AET, MEA, thioproline에 대해 각각 2.24, 2.95, 2.78, 1.23 으로, acetylbenzoylaconine은 백색마우스를 Co-60 감마선장해로 부터 방어할 수 있는 능력이 있음을 알았다.

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간호학과 여학생의 절주의도 영향요인 (Factors Affecting Female Nursing Students' Intention to Control Drinking)

  • 송효숙;임소희
    • 한국학교보건학회지
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    • 제32권2호
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    • pp.116-124
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    • 2019
  • Purpose: This study was performed to measure the influence of drinking motives, drinking refusal self-efficacy, and self-determination on the intention to control drinking among nursing students. Methods: A cross-sectional survey was done with the participation of 258 nursing students attending four universities in G city. Data collection was conducted from May to June, 2018, using a self-report questionnaire. Data were analyzed using the t-test, ANOVA, $Scheff{\acute{e}}$ test, Pearson's correlation coefficients, and Hierarchical multiple regression. Results: The average scores for drinking motives, drinking refusal self-efficacy, self-determination, and intention to control drinking were 2.29, 4.54, 3.89, and 4.29 respectively. There were significant differences in the intention to control drinking according to grade, religion, and age of alcohol initiation. The factors influencing the intention to control drinking in nursing students were identified as self-determination (${\beta}=.24$), drinking refusal self-efficacy (${\beta}=.17$) and drinking motives (${\beta}=-.17$). This factor explained 26% of the nursing students' intention to control drinking. Conclusion: Therefore, it is necessary to develop a alcohol education program to improve the drinking culture of nursing college students and to improve their self-regulation skills in order to help them form a desirable drinking habit, and it is also necessary to apply the developed intervention program and test the effect.

응급실 간호사의 폭력경험에 대한 반응, 회복탄력성이 소진에 미치는 영향 (Impact of Response to Violence and Resilience to Burnout in Emergency Department Nurses)

  • 황수연;한지영
    • 임상간호연구
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    • 제24권3호
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    • pp.303-312
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    • 2018
  • Purpose: The purpose of this study was to identify the relationship between response to violence, resilience and burnout and to investigate the factors that affect burnout in emergency room nurses. Methods: Data from 237 nurses in 15 emergency rooms were collected using a structured questionnaire. Data were analyzed using SPSS 23.0, and the analyses included descriptive statistics, t-test, Mann-Whitney test, ANOVA, Kruskall Wallis test, Pearson correlation, and hierarchical multiple regression. Results: Burnout was positively correlated with response to violence and negatively correlated with resilience in emergency room nurses. Response to violence (${\beta}=.466$, p<.001), resilience (${\beta}=-.308$, p<.001), and religion (${\beta}=-.131$, p=.011) were significant predictors of burnout, and they explained 39.9% of emergency room nurses' burnout. Conclusion: Response to violence and resilience were identified as significant factors affecting burnout in emergency room nurses. Therefore, it is necessary to develop strategies to cope effectively with violence and to develop programs that can strengthen resilience.

간호대학생의 문화적 역량이 간호전문직관에 미치는 영향 (Influence of Cultural Competence on Nursing Professionalism of Nursing Students)

  • 박미정;유하나
    • 한국간호교육학회지
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    • 제25권1호
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    • pp.38-47
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    • 2019
  • Purpose: The purpose of this study was to investigate the influence of cultural competence on nursing professionalism among nursing students in South Korea. Methods: A sample of 218 nursing students in three universities answered a self-report questionnaire. Descriptive statistics, t-test, ANOVA, Mann-Whitney U-test, Kruskal-Wallis test, Pearson's correlation analyses, and hierarchical multiple regression were used to analyze the data. Results: There were significant differences in cultural competence depending on the use of foreign language, having foreign friends, frequency of interaction with foreigners, multi-cultural education experiences, and level of demand for multicultural education. There were significant differences in nursing professionalism depending on grade level, satisfaction with major choice, college life satisfaction, and foreign language learning experience. There was a significant positive correlation between cultural competence and nursing professionalism. Lastly, significant predictors of nursing professionalism included satisfaction with major choice (${\beta}=.22$, p=.004), cultural awareness (${\beta}=.22$, p=.007) and cultural experience (${\beta}=.17$, p=.026). The regression model explained 20.2% of nursing professionalism. Conclusion: In order to establish desirable nursing professionalism, strategies for enhancing cultural awareness and cultural experiences in nursing education courses are needed both inside and outside the curriculum.