• Journal of Ginseng Research
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• v.45 no.1
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• pp.191-198
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• 2021

Background: Most clinical studies of immune responses activated by Korean Red Ginseng (KRG) have been conducted exclusively in patients. However, there is still a lack of clinical research on immune-boosting benefits of KRG for healthy persons. This study aims to confirm how KRG boosts the immune system of healthy subjects. Methods: A total of 100 healthy adult subjects were randomly divided into two groups that took either a 2 g KRG tablet or a placebo per day for 8 weeks. The primary efficacy evaluation variables included changes in T cells, B cells, and white blood cells (WBCs) before and after eight weeks of KRG ingestion. Cytokines (TNF-α, INF-γ, IL-2 and IL-4), WBC differential count, and incidence of colds were measured in the secondary efficacy evaluation variables. Safety evaluation variables were used to identify changes in laboratory test results that incorporated adverse reactions, vital signs, hematological tests, blood chemistry tests, and urinalysis. Results: Compared to the placebo group, the KRG intake group showed a significant increase in the number of T cells (CD3) and its subtypes (CD4 and CD8), B cells, and the WBC count before and after eight weeks of the intake. There were no clinically significant adverse reactions or other notable results in the safety evaluation factors observed. Conclusion: This study has proven through its eight-week intake test and subsequent analysis that KRG boosts the immune system through an increase in T cells, B cells, and WBCs, and that it is safe according to the study's safety evaluation.

• Journal of Applied Reliability
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• v.13 no.3
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• pp.165-174
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• 2013

Thruster break for aerogenerator performs a role that is stopping the rotor in case of emergency such as strong wind, system abnormality or maintenance check. In this study, failure analysis and test evaluation on the thruster break for aerogenerator are proposed, and the entire process to improve reliability of the product through design improvement is presented. The typical failure case is fatigue and wear, and failure cause on these are identified and improvement plan is presented. Lastly, reliability improvement is established to analyse test results before after the life test.

• Korean Journal of Clinical Pharmacy
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• v.16 no.2
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• pp.131-138
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• 2006

Heptaplatin, a new platinum derivative, has several contradicting reports on the nephrotoxicity. Therefore, the aim of this study is to compare the toxicities of heptaplatin-containing regimens in the chemotherapy. This study was performed retrospectively on seventy-seven patients with advanced gastric cancer who did not receive chemotherapy within the last 1 months before taking of heptaplatin- or cisplatin-containing chemotherapy. The 38 patients among total patients was received heptaplatin-containing regimens (26 with SEF regimens: heptaplatin/epirubicin/5-FU, 12 with SF regimens: heptaplatin/5-FU) and the rest 39 patients was received cisplatin-containg regimens (11 with CEF regimens: cisplatin/epirubicin/5-FU, 28 with ELF regimens: epirubicin/leucovorin/5-FU). Before and after the chemotherapy serum creatinine (Scr) and proteinuria were measured by urine stick test in all patient groups. Also Scr was measured a day before the second cycle and did not vary significantly between groups. However Scr on cycle 3 were significantly higher in SEF and SF groups. In case of proteinuria, it was more frequent on cycle 1 in heptaplatin/5-FU group. Proteinuria before and after on cycle 2 was not different between the two cisplatin -containing groups, but was more frequent in heptaplatin-containing groups. The reason why the Scr measured was not so different could be because we excluded the patients who received only one cycle of heptaplatin and changed the regimen due to signs of nephrotoxcity. As the results nephrotoxicity such as protienuria was appeared to be more frequent with heptaplatin-treated patients. It suggests that the clinical consequences of the toxicity need to further evaluation and also the modalities to prevent or minimize nephrotoxicity of heptaplatin should be studied for future utilization of the drug.

• Radiation Oncology Journal
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• v.32 no.1
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• pp.31-42
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• 2014

Purpose: To evaluate the usefulness of positron emission tomography/computed tomography (PET/CT) for field modification during radiotherapy in esophageal cancer. Materials and Methods: We conducted a retrospective study on 33 patients that underwent chemoradiotherapy (CRT). Pathologic findings were squamous cell carcinoma in 32 patients and adenocarcinoma in 1 patient. All patients underwent PET/CT scans before and during CRT (after receiving 40 Gy and before a 20 Gy boost dose). Response evaluation was determined by PET/CT using metabolic tumor volume (MTV), total glycolytic activity (TGA), MTV ratio (rMTV) and TGA ratio (rTGA), or determined by CT. rMTV and rTGA were reduction ratio of MTV and TGA between before and during CRT, respectively. Results: Significant decreases in MTV ($MTV_{2.5}$: mean 70.09%, p < 0.001) and TGA ($TGAV_{2.5}$: mean 79.08%, p < 0.001) were found between before and during CRT. Median $rMTV_{2.5}$ was 0.299 (range, 0 to 0.98) and median $rTGAV_{2.5}$ was 0.209 (range, 0 to 0.92). During CRT, PET/CT detected newly developed distant metastasis in 1 patient, and this resulted in a treatment strategy change. At a median 4 months (range, 0 to 12 months) after completion of CRT, 8 patients (24.2%) achieved clinically complete response, 11 (33.3%) partial response, 5 (15.2%) stable disease, and 9 (27.3%) disease progression. $SUV_{max}$ (p = 0.029), $rMTV_{50%}$ (p = 0.016), $rMTV_{75%}$ (p = 0.023) on intra-treatment PET were found to correlate with complete clinical response. Conclusion: PET/CT during CRT can provide additional information useful for radiotherapy planning and offer the potential for tumor response evaluation during CRT. $rMTV_{50%}$ during CRT was found to be a useful predictor of clinical response.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.19 no.1
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• pp.33-39
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• 2013

Background: The purpose of this study was to find out the effect of trunk stabilization training on the self posture control efficacy, physical self-description and perception stress in high school students. Methods: 92 voluntary students (73 females, 19 males) participated in this study. They received trunk stabilization training for 40 minutes per day and a time per week during 6 weeks period. Trunk stabilization training was an approach of education in proper posture and coordination of movement. In the evaluation, the self posture control efficacy scale (SPCES) was used to measure the posture control efficacy, the physical self-description questionnaire (PSDQ) was used to measure the physical self description and the perception stress scale (PSS) was used to measure the stress. All measurement of each subject were measured before and after stabilization training. Results: The SPCES were significantly different before and after (p<.05). The PSDQ and PSS were no significantly different before and after (p>.05) but the means were increased slightly. Conclusion: Conclusionally these results suggest that the trunk stabilization training increased the self posture control efficacy and would give help to control Students themselves.

• Hwankyungkyoyuk
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• v.22 no.3
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• pp.136-151
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• 2009

The purpose of this study was to analyze changes in perceptions of the categories of environmental education and environmental education professionalism of teachers participating in a in-service teacher training programs for environmental education. For this study, surveys and interviews were conducted before and after participation of 20 elementary and secondary school teachers who had participated in 'in-service teacher training program for professional development in environmental education' in August of 2005. Before participation, most of teachers answered that 'Education for Environment' was essential factor among the categories for environmental education. After participation, 15 teachers retained their perception but 5 teachers had changed to 'Education about Environment' or 'Education for Environment'. Environmental professionalism was conducted in '5 ability categories of environment teachers' of Hungerford et al.(1994). Categories has goal domains such as 'Goal domain I (level of basic)', 'Goal domain II (level of conceptual perceptions)', 'Goal domain III (level of investigating and evaluation)', 'Goal domain IV(level of environmental action skill)', 'Goal domain V(level of educational apply)'. Before participation, teachers had a low level of professionalism in environmental areas, but after participation environmental education professionalism improved significantly into the all 'Goal domains'.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.20 no.1
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• pp.97-115
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• 2017

The purpose of this study is to evaluate the preference and image on landscape of before and after the restoration in the four study areas where the restoration project of Baekdudaegan ecological ridgeline was carried out and to explore the change factors of image preference according to restoration project. The study areas were Beoljae, Ihwaryeong, Bijoryeong, and Yuksimnyeong and 248 questionnaires were used for analysis. As a result of the recognition analysis on restoration project of ecological ridgeline, the awareness of the project was low at 2.63, the satisfaction of the project was 3.42, and necessity of the project was 4.07. In terms of the preference analysis for landscape photographs, the all preferences of four sites were improved after the project than before. In the result of the landscape image evaluation, images such as 'lifeless', 'uniform' and 'ugly' were high before the project, however, images such as 'clean', 'tidy', and 'stable' were high after the project. As a result of analyzing the change factors of image preference according to the restoration project, adjectives such as 'beautiful-ugly' and 'open-closed' influenced the preference change in common. These findings can be utilized as the base data for the planning direction for the construction of new ecological ridgeline or the landscape conservation of existing ecological ridgeline.

• Journal of the Korea Convergence Society
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• v.12 no.7
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• pp.105-111
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• 2021

The purpose of this study is to determine how the pre-test performed before training affects the results of CPR performance. In the case of the pre-test group(PTG), a pre-evaluation was performed for 1 minute before training, and the group that did not perform the pre-test(NPTG) performed only regular education. In both groups, skill test was performed for 1 minute after training. As a result of comparing the pre and post-test of PTG, there were statistically significant changes in chest compression depth, rate, and compression recoil. There was a statistically significant difference only in the chest compression rate in the chest compression performance results of the two groups after training. There was a statistically significant difference in the results of confidence after training in both groups. It is judged that the pre-test conducted before training has a good influence not only on the results of chest compression, but also on confidence improvement. Therefore, it is judged that it is necessary to develop additional programs such as pre-education test in order to increase the concentration of CPR education for the general population.

• Journal of the Korean Home Economics Association
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• v.39 no.10
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• pp.125-140
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• 2001

The purpose of this study was to examine the children's money managment behaviors and to find out the factors affecting them. The data were collected from 507 elementary school students in Kimhae-city. Frequency distributions, Cronbach's Alpha, Pearson's correlation and regression analyses were used by SPSS Windows. The major findings from this study were as follows; (1) many children were provided with allowances by their mothers, knew their amount of allowances before they received them, and used allowance for taking snacks, (2) the factors affecting allowance planning were the source of allowances, parents' guidance before using allowances, satisfaction of the amount of allowances, the amount of watching TV, and parent-child communications about consumption, and (3) the source of allowances, recognition of the amount of allowances before children received them, parents' guidance before using allowances, parents' check after using allowances, and satisfaction of the amount of allowances had influence on the record of a cashbook and evaluation.

• Journal of the Korean Society of Radiology
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• v.16 no.7
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• pp.985-993
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• 2022

This study was conducted to compare and evaluate the expectations and satisfaction of clinical practice for students who conducted practice at clinical practice institutions of various sizes before and after COVID-19, and to suggest future clinical practice guidance methods and operation directions. There was a significant difference in the evaluation of satisfaction with practice before and after COVID-19, especially after the evaluation of satisfaction with practice guidance, practice environment, and practice time. As a result of analyzing the decisive influencing factors related to practice satisfaction, students who conducted practice at university hospitals highly evaluated the institutional environmental factors, and students who conducted practice at small and medium-sized hospitals showed high satisfaction in participation-oriented practice. Therefore, it is thought that practice that utilizes the strengths and weaknesses of university hospitals and small and medium-sized hospitals will be more effective than clinical practice that relies only on university hospitals. However, in order to diversify the training institution to small and medium-sized hospitals, it is necessary to create a manual on standardized training courses, training methods, and evaluation methods suitable for the training goals and curriculum, and provide them to the institution. In addition, if it is operated through sufficient exchange of opinions and consultation with institutions, schools will be able to obtain opportunities to cultivate practical talents, and small and medium-sized hospitals with difficulties in expanding manpower will be able to secure excellent human resources first.