• Journal of Microbiology and Biotechnology
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• 제11권1호
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• pp.131-137
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• 2001

Previous work has identified that only the catabolite responsive element A (creA; previously called cre-2) out of two potential cre sequences (cre-1: nucleotide +160 to +173 and cre-2: +173 to +186), recognized within the coding region of the xylanaseA gene (xynA) of Bacillus stearothermophilus No.236, was actually, was actually involved in the carbon catabolite repression(CCR) of xynA expression in B. subtilis. However, the level of CCR of xynA expression in the original B.stearothermophilus No.236 strain (70-fold repression). Therefore, to search for an additional cre element in the promoter region, the upstream region of the xynA gene was subcloned by chromosome walking, and as a result, another potential cre element (nucleotide -124∼-137; designated creB) was recognized in this region. The cre-like sequence revealed a high homology to the cre consensus sequence. The xylanase activity of B. subtilis MW15 bearing pWPBR14 (containing creA and creB) cultured in a medium containing xylose as the sole carbon source was about 7.7 times higher than that observed for the same culture containing glucose. B. subtilis MW15 bearing pWPBR23 (containing only creA) produced an activity about 2.4 times higher. This pattern of CCR was confirmed using derivatives of xynA::aprA fusion plasmids. Furthermore, a measurement of the amounts of the xynA transcript showed a similar pattern as that for the production of xylanase. In addition, the synthesis of xylanase in B. subtilis QB7115 [a catabolite control protein A (ccpA) mutant strain] carrying pWPBR14 was almost completely relieved from glucose repression. Together, these results lead to a conclusion that the CCR of the expression of the xynA gene is mediated by CcpA binding at creA and creB sites in B. subtilis.

• 항공우주시스템공학회지
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• 제10권1호
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• pp.21-28
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• 2016

Orbit determination problems have been interest of many researchers for long time. Due to the high nonlinearity of the equation of motion and the measurement model, it is necessary to linearize the both equations. To avoid linearization, the filter based on Fokker-Planck equation is designed. with the extended Kalman filter update mechanism, in which the associated Fokker-Planck equation was solved efficiently and accurately via discrete quadrature and the measurement update was done through the extended Kalman filter update mechanism. This filter based on the DQMOM and the EKF update is applied to the orbit determination problem with appropriate modification to mitigate the filter smugness. Unlike the extended Kalman filter, the hybrid filter based on the DQMOM and the EKF update does not require the burdensome evaluation of the Jacobian matrix and Gaussian assumption for the system, and can still provide more accurate estimations of the state than those of the extended Kalman filter especially when measurements are sparse. Simulation results indicate that the advantages of the hybrid filter based on the DQMOM and the EKF update make it a promising alternative to the extended Kalman filter for orbit estimation problems.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 춘계학술대회논문집B
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• pp.886-891
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• 2000

One of the domestic co-generation plants have undergone excessive vibration problems of turbine attributed to external force for years. The root cause of turbine vibration may be shan alignment problem which sometimes is changed by thermal expansion and external farce, even if turbine technicians perfectly performed it. To evaluate the alignment condition from plant start-up to full load, a strain measurement of turbine and main steam piping subjected to thermal loading is monitored by using strain gages. The strain gages are bonded on both bearing housing adjusting bolts and pipe stoppers which. installed in the x-direction of left-side main steam piping near the turbine inlet in order to monitor closely the effect of turbine under thermal deformation of turbine casing and main steam piping during plant full load. Also in situ load of constant support hangers in main steam piping system is measured by strain gages and its results are used to rebalance the hanger rod load. Consequently, the experimental stress analysis by using strain gages turns out to be very useful tool to diagnose the trouble and failures of not only to stationary components but to rotating machinery in power plants.

• International Journal of Fuzzy Logic and Intelligent Systems
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• 제13권1호
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• pp.1-11
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• 2013

The determination of the pose of the imaging camera is a fundamental problem in computer vision. In the monocular case, difficulties in determining the scene scale and the limitation to bearing-only measurements increase the difficulty in estimating camera pose accurately. Many mobile phones now contain inertial measurement devices, which may lend some aid to the task of determining camera pose. In this study, by means of simulation and real-world experimentation, we explore an approach to monocular camera localization that incorporates both observations of the environment and measurements from accelerometers and gyroscopes. The unscented Kalman filter was implemented for this task. Our main contribution is a novel approach to landmark initialization in a Kalman filter; we characterize the tolerance to noise that this approach allows.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2000년도 가을 학술발표회 논문집
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• pp.285-292
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• 2000

Though there has been increasing use of large diameter drilled shaft as a foundation structure of bridges, current practice for quality control is to confirm the minimum required load carrying capacity during construction stage. For economic and appropriate design of drilled shaft, it is necessary to evaluate the load transfer mechanism by pile load tests during initial stage of construction and to use the test results as a feedback to a revision of initial design. In this paper, results of load tests peformed at several domestic sites are presented to investigate the load transfer characteristics of large diameter drilled shaft. It was found that most of the load on piles is sustained by shaft friction and that only small portion of the load reaches the bottom of the drilled shaft. Some test results of drilled shaft by Pile Driving Analyzer performed at same sites are also presented to compare the load transfer characteristics interpreted from static pile load tests.

• 한국항공우주학회지
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• 제38권7호
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• pp.664-672
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• 2010

본 논문은 표적의 방향 정보만을 측정할 경우 $t_{go}$-다항식 유도법칙의 표적 가관측성 분석을 다룬다. 본 연구에서는 직접적인 방법으로 표적의 가관측성을 분석한다. 등속도 표적에 대해 가관측성을 갖기 위한 조건들이 시선각의 함수로만 주어지기 때문에, $t_{go}$-다항식 유도법칙을 적용 했을 때 시선각의 닫힌 해를 도출하고, 이 닫힌 해를 가관측성 조건에 직접 대입하므로, $t_{go}$-다항식 유도법칙의 표적 가관측성 특성을 해석한다. 표적의 가관측성은 유도법칙의 유도이득, 초기 유도 조건과 유도명령의 형상에 따라 달라진다. 최종적으로 시뮬레이션을 통해 $t_{go}$-다항식 유도법칙의 표적 가관측성을 검증한다.

• Radiation Oncology Journal
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• 제36권4호
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• pp.265-275
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• 2018

Cancer is a complex multifaceted illness that affects different patients in discrete ways. For a number of cancers the use of chemotherapy has become standard practice. Chemotherapy is a use of cytostatic drugs to cure cancer. Cytostatic agents not only affect cancer cells but also affect the growth of normal cells; leading to side effects. Because of this, radiotherapy gained importance in treating cancer. Slaughtering of cancerous cells by radiotherapy depends on the radiosensitivity of the tumor cells. Efforts to improve the therapeutic ratio have resulted in the development of compounds that increase the radiosensitivity of tumor cells or protect the normal cells from the effects of radiation. Amifostine is the only chemical radioprotector approved by the US Food and Drug Administration (FDA), but due to its side effect and toxicity, use of this compound was also failed. Hence the use of herbal radioprotectors bearing pharmacological properties is concentrated due to their low toxicity and efficacy. Notably, in silico methods can expedite drug discovery process, to lessen the compounds with unfavorable pharmacological properties at an early stage of drug development. Hence a detailed perspective of these properties, in accordance with their prediction and measurement, are pivotal for a successful identification of radioprotectors by drug discovery process.

• 한국항해학회지
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• 제7권2호
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• pp.1-45
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• 1983

This paper concerns the applications of the Kalman filter to navigation and the develment of computer programs of the navigational calculations. Methods to apply the Kalman filter to celestial fix, fix by cross bearing and cocked hat are proposed, and numerical simulations under various noise conditiions are conducted. The accuracy of the optimal positions obtained by the Kalman filter is compared with that of the fixed positiions by radial error method. In the case of celestial fix, an algorithm to estimate the optimal positions by using the linear Kalman filter is presented. The optimal positions by the Kalman filter are compared with the running fixes and with the most probable positions obtained from a single line of position. It is confirmed that the resutls of the proposed method are more accurate than the others. In practical piloting, bearings are generally measured intermittently and the measurement process is nonlinear. It is, therefore, difficult for us to apply the Kalman filter to fix by cross bearing. In order to be used in such an unfavorable case, the extended Kalman filter is revised and the aplicability of the revised extended Kalman filter is checked by numerical simulation under various noise conditions. In a cocked hat, an inside or outside fix is dependent only upon azimuth spread, if the error of each line of position is assumed to be equal both in magnitude and sign. A new technique of selecting a ship's position between an inside fix and an outside fix in a cocked hat by using fix determinant derived from the equation of three lines of position is also presented. The relations among the optimal position by Kalman filter, incentre (or excentre) and random error centtre of the cocked hat are discussed theoretically and the accuracy of the optimal position is compared with that of the others by numerical simulation.

• 자원환경지질
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• 제32권3호
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• pp.307-315
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• 1999

Four organic polymers were mixed with mothmorillonite. Two cationic polymers a hi로 molecular weight polyacrylamide (494C) and a low molecular weight polymer (587C).Two anionic polymers include a high molecular weight polymer (aerotil). Each clay supension series were allowed to stand for 24 hours and were centrifuged, and the clay plugs were washed and dried. The dried samples investigated by XRD, IR and CEC measurement. The suspended clay containing anionic polymers was not flocculated at any concentratuons of polymer. But the suspendions containing two cationic polymers were rapidly flocculated at almost all concentrations. the d(001) spacings of Na-montmorillonite after being with cationic polymer 587C show about 15$\AA$ suggesting the polymers may have entered the interlayer spaces. The polymer 494C-treated sample produced double peaks of about 12 and 15$\AA$ in XRD. It indicates that the high molecular weight polymer. And cationic polymer 494C may be adsorbed mainy on the outside surface of clay, and some polymers may peretrate into olny interlayers in the margin of montmorillonite particles because of its high molecular weught. CEC of polumer 587-treated sample was reduecd mmarkedly suggesting polymer blocks CEC sites. The d(001) spacings of Ca-montmorillonite after being treated with cationic polymers show about 15$\AA$ suggesting that the interlayer spaces have not been expanded. In the experiment using a dilute Ca-bearing solution, the suspended caly containinf anionic polymers was flocculated. The results indicate that the flocculation behavior of montmorillonite-polymer supension depends on not only polymer properties such as concentration, electric charge and molecular weight but also compositions of solvent.

• Journal of Advanced Marine Engineering and Technology
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• 제39권1호
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• pp.28-31
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• 2015

전기기기나 엔진의 축은 여러 가지 원인으로 축기전력이 발생한다. 이런 축과 베어링이 윤활유로 절연되어 있어 콘덴서를 이루고 있고, 콘덴서와 같은 역할로 기전력을 축적하고 있다. 이 축 기전력은 선체에 비해 극히 일부를 제외하고 +전압을 갖고 있다. 이 +전압이 축의 전기 스파크를 일으켜 부식을 야기 시킬 수 있다. 이 부식을 막기 위해 선박에서는 샤프트 그라운드 시스템을 설치하여 운용하고 있다. 이 축기전력을 측정은 프로펠러 축의 전압과 메인엔진의 회전수를 동시에 측정하였다. 측정장치는 내셔널인스트루먼트사의 24비트 A/D컨버터를 사용하여 측정하였고, 프로그램은 Lab View를 사용하였다. 본 논문은 축에 발생되는 기전력을 분석하였고, 분석결과를 이용하여 모델링을 하였다. 결과로 축기전력은 메인엔진의 회전수에 따라 비례하다가 일정회전수를 넘어가면 감소하는 경향을 보였다. 후진보다는 전진이 축기전력이 높은 결과를 얻었다. 전체기전력에 비하면 지구자기의 기전력은 미미하였다.