• 제목/요약/키워드: basic research

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부인복 길원형 제도법에 관한 비교연구 (A Comparative Research on the Drafting Method of the Basic Basuc Bodice Patterns for Women)

  • 구미지
    • 대한가정학회지
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    • 제32권2호
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    • pp.219-230
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    • 1994
  • The purpose of this comparative research is to investigate the change of the drafting method of the basic patterns for women in Korea. Followings were the findings of this research: 1) The concept of the basic pattern could be found after the first of the 1950s and there was introduction of the many basic patterns. At first measurement couldn't be found. Gradually the personal body type could be expressed in the basic pattern through the practical measurements such as the width of highest bust level and the length of neck to bust. 2) Through the ages the changes of the basic patterns were between 1950,60s and 1980,90s distinctively at the back width back shoulder angle front and back shoulder height from biceps line back neck ratio(height/width) BP position at the biceps line the amounts of underarm dart underarm dart position from the biceps lines and front ease angle at BP line. 3) 4 Grouping the types of the basic pattern followings are their characters; 1st Munwha or Doreme style 2nd waist dart group 3rd underarm dart and rectangular front ease 4th the usage of many measurements like as front length upper bust girth etc.

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The Impact of Basic Psychological Needs Satisfaction on the Performance of the Franchisee

  • KIM, Suyeong;YOUN, Sajean;MOON, Jaeseung
    • 유통과학연구
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    • 제19권1호
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    • pp.17-26
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    • 2021
  • Purpose: This research is to investigate the effect of the franchisee's basic psychological needs satisfaction on its business performance. Moreover, within the relationship between the franchisee's basic psychological needs satisfaction and its performance, the current study examined the mediating effect of work engagement and the moderating effect of the franchisor's support. Research design, data and methodology: 367 survey data were collected and analyzed using SPSS 22 and AMOS 22. For the assessment of goodness of fit of the models, fit indexes such as TLI, CFI, RMSEA were employed. Results: The results of the study are as follows: first, the franchisee's basic psychological needs satisfaction is positively related to performance; second, the franchisee's basic psychological needs satisfaction is positively related to work engagement; third, the franchisee's work engagement is positively related to performance; fourth, it is uncovered that the franchisee's work engagement mediates the relationship between basic psychological needs satisfaction and business performance; fifth, the moderating effect of the franchisor's support was insignificant. Conclusion: This study would like to contribute to the field of franchise performance, by re-assessing the significance of the individual's characteristics (of the franchisee) which has been ignored thus far. Furthermore, the limitations of the study and future research directions were discussed.

한국의 기초연구능력 구축과정 : 우수연구센터(ERC/SRC) 제도를 중심으로 (The Accumulation Process of Basic Research Capability in Korea : Case Study on ERC/SRC)

  • 황혜란;윤정로
    • 기술혁신학회지
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    • 제6권1호
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    • pp.1-19
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    • 2003
  • The mechanism of knowledge production in the basic science has been changed throughout the development process in Korea. During the 1970s, the focus resides in the support of individual scientists while it concentrated on the support of research organization, centered on center of excellence from the 1980s. The change in the sup-porting mechanism to basic science result in the transformation of knowledge production system in the university and impact on the behavior of individual scientists. This paper focuses on the co-evolution process between newly adopted supporting program for basic science and the knowledge production system via the case study of representative program of center of excellence supporting program in Korea.

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3차원 계측장치를 이용한 길 원형의 여유량 분석 (Analysis of the Ease in Basic Bodice Pattern Using 3-D Measuring Instrument)

  • 심규남;서정권;이원자
    • 한국의류산업학회지
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    • 제2권3호
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    • pp.239-245
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    • 2000
  • The purpose of this study was for analysis of ease about basic bodice pattern, as the first step of the research process for the drawing method of basic bodice for women in their twenties. The five selected basic bodice were made and they were worn by FRP body The garment space of each bodice was measured by analysis of the garment space of each section in figure of polymerization of cross section by a 3-D measuring instrument. The research suggests that this compared analysis is an objective reference. This analysis not only of the area of cross section of garment space and ease but also of the girth of the body shape and wearing shape, using the PAD system and 3-D measuring instrument, can be helpful in making garment patterns.

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Folate Receptor-Specific Positron Emission Tomography Imaging with Folic Acid-Conjugated Tissue Inhibitor of Metalloproteinase-2

  • Kim, Sung-Min;Choi, Naeun;Hwang, Seungkyun;Yim, Min Su;Lee, Jung-Sik;Lee, Sang-Mok;Cho, Gyunggoo;Ryu, Eun Kyoung
    • Bulletin of the Korean Chemical Society
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    • 제34권11호
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    • pp.3243-3248
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    • 2013
  • The tissue inhibitor of metalloproteinase-2 (TIMP-2) inhibits matrix metalloproteinases activity and modulates cellular proliferation and apoptosis. The human serum albumin-TIMP-2 with folic acid conjugate (termed HT2-folate) was synthesized to promote uptake through folate receptors (FRs), and a corresponding radio-labeled compound was prepared for tumor diagnosis by positron emission tomography (PET). $^{68}Ga$-NOTA-HT2-folate was synthesized from $^{68}Ga$ and the NOTA chelator with HT2-folate. The fusion protein was identified using MALDI-TOF mass spectrometry. The radioligand was prepared with a high radiochemical yield. Cell-surface association of $^{68}Ga$-NOTA-HT2-folate significantly increased over time in FR-positive tumor cells. In animal PET and biodistribution studies, tumor uptake was very high as early as 1 h after radioligand injection. Folate conjugation enhanced the selective receptor-targeting efficacy of HT2 in FRexpressing tumors, and its radioligand will be useful as an in vitro tool and for in vivo tumor diagnosis by PET imaging.

Molecular Imaging of Arthritis in the Angiogenic Vasculature Using A 123I-Vascular Endothelial Growth Factor Receptor Antibody

  • Kim, Sung-Min;Choi, Na-Eun;Song, Young-Kyu;Cho, Gyung-Goo;Bang, Jeong-Kyu;Kim, Sang-Mi;Lee, Sang-Hoon;Ryu, Eun-Kyoung
    • Bulletin of the Korean Chemical Society
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    • 제33권6호
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    • pp.1890-1894
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    • 2012
  • Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been implicated in the pathogenesis of rheumatoid arthritis, which is angiogenesis dependent. Antibody-based molecular imaging improves targeting, and antibody radiolabeling is useful for monitoring biological events $in$ $vivo$ $via$ PET or SPECT. We investigated the potential of molecular imaging to diagnose arthritis with VEGFR-2 $in$ $vivo$. The $^{123}I$-VEGFR-2 antibody was prepared by the iodogen tube method. The radioligand was injected into arthritic mice, and micro SPECT/CT was performed. The arthritic mice were examined by 4.7-T MRI and immunohistochemistry. The $^{123}I$-VEGFR-2 antibody showed high uptake in the arthritic region at 1 h postinjection on SPECT/CT but no uptake in the control animals after radioligand injection. In MR images, the arthritic tissue of the mice was correlated with regions labeled by the $^{123}I$-VEGFR-2 antibody. Immunohistochemical localization showed markedly increased expression of VEGFR-2 in the endothelial cells, fibroblasts, and macrophages of the arthritic mice.

A Simple Purification Procedure of Biologically Active Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (hGM-CSF) Secreted in Rice Cell Suspension Culture

  • Sharma Niti;Park Seung Moon;Kwon Tae Ho;Kim Dae Hyuk;Yang Moon Sik
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제9권6호
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    • pp.423-427
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    • 2004
  • A simple purification procedure of bioactive human granulocyte macrophage colony stimulating factor (hGM-CSF) secreted in rice cell suspension culture has previously been described. In this study the protein was purified to apparent homogeneity with an overall yield of $80.1\%$ by ammonium sulfate precipitation and a single chromatographic step involving FPLCanion exchange chromatography. The purified hGM-CSF revealed at least five glycosylated forms ranging from $21.5{\~}29$ kDa, and its biological activity was independent of the glycosylation pattern. This is the first purification report of recombinant hGM-CSF to apparent homogeneity from rice cell suspension cultures.

Comparative Toxicity Studies of Ultra-Pure Ag, Au, Co, and Cu Nanoparticles Generated by Laser Ablation in Biocompatible Aqueous Solution

  • Kim, Yea-Seul;Kim, Kuk-Ki;Shin, Seon-Mi;Park, Seung-Min;Hah, Sang-Soo
    • Bulletin of the Korean Chemical Society
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    • 제33권10호
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    • pp.3265-3268
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    • 2012
  • Nanoparticles (NPs) are increasingly used in consumer products, which have aroused many concerns and debates regarding their fate in biological systems from a point of their safety/toxicity. Although a number of studies on the biological effects of NPs have been published, these are often complicated by the possible toxicity of conventional NPs, caused by contamination with chemical precursors or additives during their synthesis and/or purification procedures. To explicitly understand the toxicity basis of NPs, it is necessary to directly address a main problem related to their intrinsic/inherent toxicity and/or incompatibility with biological objects. The present study is designed to take advantage of a novel laser-assisted method called laser ablation to generate Ag, Au, Co, and Cu NPs in biocompatible aqueous solution, and to evaluate the toxicity of the resulting ultra-pure NPs. Our results show that the ultra-pure NPs with nascent surfaces possess moderate cytotoxicity to human cells in a cell-dependent manner.

Ionic Liquids Containing 1,1-Dicyano-1-acetylmethanide Anion as Potential Electrolytes

  • Winoto, Haryo Pandu;Agarwal, Shalu;Im, Jin-Kyu;Cheong, Min-Serk;Lee, Je-Seung
    • Bulletin of the Korean Chemical Society
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    • 제33권9호
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    • pp.2999-3003
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    • 2012
  • Various types of room temperature ionic liquids (RTILs) containing 1,1-dicyano-1-acetylmethanide anion ($[C(CN)_2(COCH_3)]^-$, $[DCNAcC]^-$) were prepared and their physical and electrochemical properties were studied. All of these ILs exhibited high thermal stabilities over $200^{\circ}C$ and relatively high ionic conductivities up to 29.4 $mS\;cm^{-1}$ at $80^{\circ}C$. Although the ionic conductivity of IL containing bis(trifluoromethanesulfonyl)-imide ($[Tf_2N]^-$) anion is higher than that of ILs bearing $[DCNAcC]^-$ anion, the specific capacitance of ILs bearing $[DCNAcC]^-$ anion are higher than that of IL containing $[Tf_2N]^-$ anion and showed high temperature dependence. Such favorable electrochemical properties of these ILs are likely to be attributed to the efficient dissociation of cation and anion at higher temperature and enhanced electrosorption of $[DCNAcC]^-$ anion at the electrode.