• Title/Summary/Keyword: baseline sensitivity

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Sensitivity Analysis of Long Baseline System with Three Transponders (세 개의 트랜스폰더로 이루어진 장기선 위치추적장치의 민감도 해석)

  • Kim, Sea-Moon;Lee, Pan-Mook;Lee, Chong-Moo;Lim, Yong-Kon
    • Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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    • 2003.05a
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    • pp.27-31
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    • 2003
  • Underwater acoustic navigation systems are classified into three systems: ultra-short baseline (USBL), short baseline (SBL), and long baseline (LBL). Because the USBL system estimates the angle of a submersible, the estimation error becomes large if the submersible is far from the USBL transducer array mounted under a support vessel. SBL and LBL systems estimate submersible's location more accurately because they have wider distribution of measuring sensors. Especially LBL systems are widely used as a navigation system for deep ocean applications. Although it is most accurate system it still has estimation errors because of noise, measurement error, refraction and multi-path of acoustic signal, or wrong information of the distributed transponders. In this paper the estimation error of the LBL system are analyzed from a point of sensitivity. It is assumed that the error exists only in the distance between a submersible and the transponders. For this purpose sensitivity of the estimated position with respect to relative distances between them is analyzed. The result says that estimation error is small if the submersible is close to transponders but not near the ocean bottom.

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Predictive Value of Baseline Plasma D-dimers for Chemotherapy-induced Thrombocytopenia in Patients with Stage III Colon Cancer: A Pilot Study

  • Tanriverdi, Ozgur
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.293-297
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    • 2013
  • Background: : Chemotherapy-induced thrombocytopenia (CIT) is an important cause of morbitity in patients with cancer. Aim: To investigate the effect of the baseline plasma D-dimer level, an important marker for thrombotic activity, on chemotherapy-induced thrombocytopenia in patients with stage III colon cancer. Materials and Methods: A total of 43 (28 men) eligible patients were divided into two groups according to whether they exhibited chemotherapy-induced thrombocytopenia: Group 1 (n=21) and Group 2 (n=22). Comparison was made using demographic, histopathologic, and laboratory variables. Additionally, baseline plasma D-dimer levels underwent receiver operation characteristics curve analysis, and areas under the curve were calculated. Sensitivity, specificity, and positive and negative likelihood rates were then determined. Results: The incidence of chemotherapy-induced thrombocytopenia had a significant correlation with baseline platelet count (r=0.568, P=0.031) and baseline plasma D-dimer levels (r=0.617, P=0.036). When the cut-off point for the latter was set as 498 ng/mL, the area under the curve was 0.89 (95%CI: 0.74-0.93), the sensitivity was 91.4%, the specificity was 89.7%, the positive likelihood rate was 3.64 and the negative likelihood rate was 0.24 for chemotherapy-induced thrombocytopenia diagnosis. Conclusions: The baseline level of plasma D-dimer could help to differentiate high-risk patients for chemotherapy-induced thrombocytopenia.

Orbit Ephemeris Failure Detection in a GNSS Regional Application

  • Ahn, Jongsun;Lee, Young Jae;Won, Dae Hee;Jun, Hyang-Sig;Yeom, Chanhong;Sung, Sangkyung;Lee, Jeong-Oog
    • International Journal of Aeronautical and Space Sciences
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    • v.16 no.1
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    • pp.89-101
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    • 2015
  • To satisfy civil aviation requirements using the Global Navigation Satellite System (GNSS), it is important to guarantee system integrity. In this work, we propose a fault detection algorithm for GNSS ephemeris anomalies. The basic principle concerns baseline length estimation with GNSS measurements (pseudorange, broadcasted ephemerides). The estimated baseline length is subtracted from the true baseline length, computed using the exact surveyed ground antenna positions. If this subtracted value differs by more than a given threshold, this indicates that an ephemeris anomaly has been detected. This algorithm is suitable for detecting Type A ephemeris failure, and more advantageous for use with multiple stations with various long baseline vectors. The principles of the algorithm, sensitivity analysis, minimum detectable error (MDE), and protection level derivation are described and we verify the sensitivity analysis and algorithm availability based on real GPS data in Korea. Consequently, this algorithm is appropriate for GNSS regional implementation.

Efficient baseline suppression via TIP and modified DEPTH

  • Hyun, Namgoong
    • Journal of the Korean Magnetic Resonance Society
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    • v.26 no.4
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    • pp.51-58
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    • 2022
  • The baseline flattened NMR spectrum has been achieved by several methodologies including pulse manipulation with a series of phase cycling. The background signal inherent in the probe is also main source of baseline distortion both in solution and solid NMR. The simple direct polarization with 90° pulse flipping the magnetization from the z-axis onto the receiver coil requires the strong rf pulse enough to encompass the wide frequency range to excite the resonance of interest nuclei. Albeit the perfect polarization 90° pulse, the signal from the unwanted magnetic fields such as background signal can not be completely suppressed by suitable phase cycling. Moreover, slowly baseline wiggling signal from the low 𝛾 nuclei is not easy to eliminate with multiple pulse manipulation. So there is still need to contrive the new scheme for that purpose in an adroit manner. In this article new triple pulse excitation schemes for TIP and modified DEPTH pulse sequence are analytically examined in terms of arbitrary phase and flip angle of pulse. The suitable phase cycling for these pulse trains is necessary for the good sensitivity and resolution of the spectrum. It is observed that the 13C sensitivity TIP experiment is almost equal to the CP/MAS with modified DEPTH sequence, both of which are applicable to both solid and solution state NMR.

Shape Optimization for Improving Fatigue Life of a Lower Control Arm Using the Experimental Design (실험계획법을 적용한 Lower Control Arm의 피로수명 형상 최적설계)

  • 김민수;이창욱;손성효;임홍재;허승진
    • Transactions of the Korean Society of Automotive Engineers
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    • v.11 no.3
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    • pp.161-166
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    • 2003
  • In order to improve the fatigue lift of a lower control arm in the vehicle suspension, a new shape optimization procedure is presented. In this approach, the shape control point concept is introduced to reduce the numbers of shape design variables. Also, the two-level orthogonal way is employed to evaluate the design sensitivity of fatigue life with respect to those shape design variables, because the analytical design sensitivity information is not directly supplied from the commercial CAE softwares. In this approach, only the six design variables are used to approximate the shape of lower control arm. Then, performed are only 10 fatigue life analyses including the baseline design, 8 DOE models and the final design. The final design, the best combination obtained from the sensitivity information, can maximize the fatigue lift nearly two times as that of the baseline design, while reducing the 12 percentage of weight than it.

Damage Identification in Truss Bridges using Damage Index Method (손상지수법을 이용한 트러스 교량의 손상추정)

  • Lee, Bong Hak;Kim, Jeong Tae;Chang, Dong Il
    • Journal of Korean Society of Steel Construction
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    • v.10 no.2 s.35
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    • pp.279-290
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    • 1998
  • An existing Damage Index Method is verified to demonstrate its feasibility for detecting structural damage in truss bridges (1) for which modal parameters are available for a few modes of vibration and (2) for which baseline modal information is not available from its as-built state. The theory of approach to detect locations of damage and to identify baseline modal model is summarized on the basis of system identification theory and modal sensitivity theory. The feasibility of the Damage Index Method is demonstrated using a numerical example of a truss bridge with 11 subsystems of 211 members and for which only two modes of vibration were recorded for post-damaged state.

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Effects of Active Oral Play and Ayres Sensory Integration (ASI®) for Child With Oral Defensiveness: Single Subject Research (구강방어아동을 위한 능동적 구강놀이와 ASI적용효과 : 단일사례연구)

  • Sung, Ga-young;Choi, Jeong-Sil;Jung, Hyerim
    • The Journal of Korean Academy of Sensory Integration
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    • v.17 no.3
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    • pp.1-13
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    • 2019
  • Objective : The purpose of the present study is to investigate the effects of Ayres Sensory Integration (ASI®) with play-centered oral defensiveness reduction activities on the oral sensitivity of a child with oral defensiveness. Methods : The subject was a three-and-a-half year-old boy with a developmental delay. The study was performed from August to September, 2018. The research design used in this study is the design for single-subject research. The experimental period was divided into three phases: three sessions for the initial baseline phase (A), 15 sessions for the treatment phase (B), and three sessions for the final baseline phase (A'). Ayres Sensory Integration (ASI®) with active oral play was conducted in the treatment phase. The Measuring Oral Sensitivity in Practice was used to test changes in the oral sensitivity level. The Korean Children's Eating Behavior Inventory and Food Checklist were used to assess the difference in functions related to oral sensitivity before and after the intervention. Results : In comparison with the baseline phase, the Measuring Oral Sensitivity in Practice and Korean Children's Eating Behavior Inventory were improved during the treatment phase, but the Food Intake checklist score was not changed after the treatment phase. Conclusion : The use of Ayres Sensory Integration (ASI®) with active oral play produced positive results and reduced the child's oral sensitivity and eating problems.

Lifetime Risk Assessment of Lung Cancer Incidence for Nonsmokers in Japan Considering the Joint Effect of Radiation and Smoking Based on the Life Span Study of Atomic Bomb Survivors

  • Shimada, Kazumasa;Kai, Michiaki
    • Journal of Radiation Protection and Research
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    • v.46 no.3
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    • pp.83-97
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    • 2021
  • Background: The lifetime risk of lung cancer incidence due to radiation for nonsmokers is overestimated because of the use of the average cancer baseline risk among a mixed population, including smokers. In recent years, the generalized multiplicative (GM)-excess relative risk (ERR) model has been developed in the life span study of atomic bomb survivors to consider the joint effect of radiation and smoking. Based on this background, this paper discusses the issues of radiation risk assessment considering smoking in two parts. Materials and Methods: In Part 1, we proposed a simple method of estimating the baseline risk for nonsmokers using current smoking data. We performed sensitivity analysis on baseline risk estimation to discuss the birth cohort effects. In Part 2, we applied the GM-ERR model for Japanese smokers to calculate lifetime attributable risk (LAR). We also performed a sensitivity analysis using other ERR models (e.g., simple additive (SA)-ERR model). Results and Discussion: In Part 1, the lifetime baseline risk from mixed population including smokers to nonsmokers decreased by 54% (44%-60%) for males and 24% (18%-29%) for females. In Part 2, comparison of LAR between SA- and GM-ERR models showed that if the radiation dose was ≤200 mGy or less, the difference between these ERR models was within the standard deviation of LAR due to the uncertainty of smoking information. Conclusion: The use of mixed population for baseline risk assessment overestimates the risk for lung cancer due to low-dose radiation exposure in Japanese males.

A Population Viability Analysis (PVA) for Re-introduction of the Oriental White Stork (Ciconia boyciana) in Korea

  • Sung, Ha-Cheol;Park, Shi-Ryong;Cheong, Seokwan
    • Korean Journal of Environmental Biology
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    • v.30 no.4
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    • pp.307-313
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    • 2012
  • The Oriental White Stork (Ciconia boyciana) is a representative wetland species distributed across East Asia. The species has been declined to face the threat of species extinctions with estimation of at about 3000 individuals. In order to re-introduce the endangered storks in the field, we developed a baseline model using the program VORTEX, performed sensitivity test, and finally suggested an ideal model based on results of the sensitivity test. The baseline model predicted 12.5% extinction probability with mean time to first extinction of 82.0 year. Sensitivity test revealed that two demographic variables (first-year mortality and percent of adult female breeding) had the greatest impacts on population persistence. Thus, corrected model improved the population persistence, where the extinction probability decreased to 1.0% in 100 years by changing values of two variables within a range of applicable to the population. Our models for stork re-introduction suggest this population will be stable by improving first-year mortality and adult female fecundity.

The clinical effects of a hydroxyapatite containing toothpaste for dentine hypersensitivity (민감성 치아에 대한 수산화인회석 함유 치약의 임상적 효과)

  • Kim, Su-Hwan;Park, Jun-Beom;Lee, Chul-Woo;Koo, Ki-Tae;Kim, Tae-Il;Seol, Yang-Jo;Lee, Yong-Moo;Ku, Young;Chung, Chong-Pyung;Rhyu, In-Chul
    • Journal of Periodontal and Implant Science
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    • v.39 no.1
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    • pp.87-94
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    • 2009
  • Purpose: The aim of this study was to compare the effectiveness of hydroxyapatite containing toothpaste with positive control toothpastes in reducing dentine hypersensitivity. Materials and methods: This clinical trial was a double-blind, randomized, parallel group comparison of two, namely hydroxyapatite containing toothpaste and strontium chloride containing toothpaste. A total of 55 subjects were included in this study. The subjects were given randomly assigned one of the two toothpastes after received tooth brushing instruction at baseline. Some clinical indices(PI, GI, PD), verbal rating score(VRS) for sensitivity to stimulus, the effect in relieving sensitivity and visual analogue scale(VAS) for sensitivity at baseline, week 2, week 4 and week 8 were assessed. All data were evaluated by intention-to-treat analysis. Results: Overall, PI and GI scores were significantly reduced compare baseline in all groups(p<0.05). In addition, there was significant difference in PI at 4 weeks and in GI at 4, 8 weeks between groups. The proportions of subjects relieved sensitivity were 70.4% in experimental group and 57.1% in control group at 8 weeks respectively. The VRS for sensitivity to three kinds of stimuli and VAS for sensitivity decreased according to time, there was no overall difference between two groups(p>0.05). Conclusion: This study demonstrated that the new hydroxyapatite containing toothpaste was similarly effective in reducing dentine hypersensitivity with pre-existing benchmark toothpaste.