• Title/Summary/Keyword: baseline risk

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Factors Associated with Suicide Risk in Advanced Cancer Patients: A Cross-Sectional Study

  • Park, Sun A;Chung, Seung Hyun;Lee, Youngjin
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.11
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    • pp.4831-4836
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    • 2016
  • The study aimed to find out to what degree suicidal thoughts and associated factors affect the suicide risk of advanced cancer patients. The frequency of suicidal thoughts among patients with cancer, especially in the advanced stages, is about 3 times greater than the adult average in South Korea. We recruited 457 participants with four types of cancers (colon, breast, cervical, and lung) using stratified sampling. Data collection was carried out through one-on-one interviews by trained nurses using a structured questionnaire. Advanced cancer patients with high, vs. low, levels of anxiety and pain had a higher suicide risk. In contrast, having one's spouse as the primary care provider was associated with a low suicide risk. Overall, the three factors of anxiety, pain, and the primary caregiver being one's spouse explained 17.2% of the variance in suicide risk. In conclusion, we derived influencing factors of suicide risk using a sample of patients with various types of advanced cancer. The results provide systematic baseline data for preparing nurse-led interventions to prevent suicidal thoughts and suicide attempts among advanced cancer patients.

Comparable Ablation Efficiency of 30 and 100 mCi of I-131 for Low to Intermediate Risk Thyroid Cancers Using Triple Negative Criteria

  • Fatima, Nosheen;Zaman, Maseeh uz;Zaman, Areeba;Zaman, Unaiza;Tahseen, Rabia
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1115-1118
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    • 2016
  • Background: There is controversy about ablation efficacy of low or high doses of radioiodine-131 (RAI) in patients with differentiated thyroid cancers (DTC). The purpose of this prospective study was to determine efficacy of 30 mCi and 100 mCi of RAI to achieve successful ablation in patients with low to intermediate risk DTC. Materials and Methods: This prospective cross sectional study was conducted from April 2013 to November 2015. Inclusion criteria were patients of either gender, 18 years or older, having low to intermediate risk papillary and follicular thyroid cancers with T1-3, N0/N1/Nx but no evidence of distant metastasis. Thirty-nine patients were administered 30 mCi of RAI while 61 patients were given 100 mCi. Informed consent was acquired from all patients and counseling was done by nuclear physicians regarding benefits and possible side effects of RAI. After an average of 6 months (range 6-16 months; 2-3 weeks after thyroxin withdrawal), these patients were followed up for stimulated TSH, thyroglobulin (sTg) and thyroglobulin antibodies, ultrasound neck (U/S) and a diagnostic whole body iodine scan (WBIS) for ablation outcome. Successful ablation was concluded with stimulated Tg< 2ng/ml with negative antibodies, negative U/S and a negative diagnostic WBIS (triple negative criteria). ROC curve analysis was used to find diagnostic strength of baseline sTg to predict successful ablation. Results: Successful ablation based upon triple negative criteria was 56% in the low dose and 57% in the high dose group (non-significant difference). Based on a single criterion (follow-up sTg<2 ng/ml), values were 82% and 77% (again non-significant). The ROC curve revealed that a baseline sTg level ${\leq}7.4ng/ml$ had the highest diagnostic strength to predict successful ablation in all patients. Conclusions: We conclude that 30 mCi of RAI has similar ablation success to 100 mCi dose in patients with low to intermediate risk DTC. A baseline $sTg{\leq}7.4ng/ml$ is a strong predictor of successful ablation in all patients. Low dose RAI is safer, more cost effective and more convenient for patients and healthcare providers.

Weight Gain and Alcohol Drinking Associations with Breast Cancer Risk in Japanese Postmenopausal Women - Results from the Japan Collaborative Cohort (JACC) Study

  • Nitta, Junichi;Nojima, Masanori;Ohnishi, Hirofumi;Mori, Mitsuru;Wakai, Kenji;Suzuki, Sadao;Fujino, Yoshihisa;Lin, Yingsong;Tamakoshi, Koji;Tamakoshi, Akiko
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1437-1443
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    • 2016
  • Background: We investigated four factors, height, weight gain since age 20, physical activity, and alcohol drinking, for associations with risk of breast cancer (BC) according to menopausal status, using the latest data of the Japan Collaborative Cohort Study (JACC Study). Materials and Methods: We confined the analysis to 24 areas available of cancer incidence information, excluding women with a previous diagnosis of BC. Baseline data were collected from 38,610 (9,367 premenopausal, and 29,243 postmenopausal) women during 1988 and 1990. The study subjects were followed-up at the end of 2009, and 273 (84 premenopausal, and 189 postmenopausal) cases of BC were newly diagnosed in 501,907 person-years. The Cox model was used to estimate a hazards ratio (HR) and its 95% confidence interval (CI) of BC risk. Results: As a result of the multivariate analysis adjusting for age at baseline survey, age at menarche, number of live births, and, age at first delivery, weight gain since age 20 of 6.7 kg-9.9 kg, and ${\geq}10.0kg$ were significantly associated with increased risk for postmenopausal BC (HR=2.48, 95% CI 1.40-4.41, and, HR=2.94, 95% CI 1.84-4.70, respectively). Significantly increased trend of BC risk was also observed in weight gain since age 20 (p for trend, p<0.001). Amount of ethanol intake per day${\geq}15.0g$ was significantly associated with increased risk for postmenopausal BC in the multivariable-adjusted analysis (HR=2.74, 95% CI 1.32-5.70). Conclusions: Higher weight gain in adulthood and larger amounts of ethanol intake were significantly associated with increased risk of BC in Japanese postmenopausal women. None of the investigated factors were significantly associated with BC risk in Japanese premenopausal women.

Evaluation of Excess Lung Cancer Risk in Korean due to Indoor Exposure to Natural $^{222}Rn$ Progenies (한국인의 실내 라돈-222 자핵종 피폭으로 인한 초과 폐암위험)

  • Chang, Si-Young;Ha, Chung-Woo;Lee, Byung-Hun
    • Journal of Radiation Protection and Research
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    • v.17 no.1
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    • pp.57-70
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    • 1992
  • An excess risk of lung cancer mortality among Koreans, attributable to indoor $^{222}Rn$ daughters exposure, were quantitatively evaluated by applying a stochastic health risk projection model on the radiation exposure. The lung cancer rate in Korean males and females, based on the 1989 demographic data, were estimated to be $22.4/10^5-y\;and\;9.5/10^5-y$, respectively The lifetime baseline lung cancer risks, deduced from these rates, appeared to be 0.047 and 0.019 for males and females, respectively, and were lower than the corresponding 1984 values of 0.067 and 0.025 in the U.S.A. The excess risk coefficients, derived by modified relative risk projection model of the BEIR-IV Committee under the US National Academy of Science, per annual 1.0 WLM of exposure to indoor radon daughters were estimated to be 0.022/WLM for males, 0.009/WLM for females, and 0.017/WLM for both sexes. The resulting annual frequency of excess lung cancer mortality for the life expectancy in the Korean population appeared to be 230/10^6-WLM, which was an approximate median of $120{\sim}450/10^6-WLM$ reported so far in the world.

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Risk perception and safety practice of paramedic students (응급구조학과 학생들의 교통 및 재난에 대한 위험인식 및 안전실천에 관한 연구)

  • Lee, Kyoung-Youl
    • The Korean Journal of Emergency Medical Services
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    • v.20 no.1
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    • pp.71-82
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    • 2016
  • Purpose: This research aimed to provide baseline data for undergraduate safety education by evaluating paramedic student risk perception and safety practice behavior regarding transport and disaster-related accidents. Methods: A total of 367 paramedic students at three different universities were surveyed using questionnaires. Risk perception questions about hazard, feeling of dread, and uncontrollable factors regarding seven items in transport and disasters were asked on a 7-point scale. Safety practice behavior consisted of 14 transport-related questions and 12 disaster-related questions in 4-point scale. All data were analyzed using SPSS Window 21.0. Results: Of 367 surveyed, 54.8% (201) were females, and 28.9% (106) were freshmen. In risk perception, 'drunk driving' in transport was the highest on average obtaining 6.49 points for hazard and 5.12 points for the feeling of dread. In disasters, 'war' recorded the highest average with 6.61 points for hazard and 5.71 points for the feeling of dread. In safety practice behavior regarding transport and disasters, a higher awareness of the need for safety education correlated with a significantly higher the rate of safety practice behavior (p <.001 respectively). Conclusion: The results indicate that undergraduates have inadequate perception of risk in emergencies. Safety education programs are needed to raise awareness of risks and to increase the safety practice rate.

Effects of Motivation-Enhancing Program on Health Behaviors, Cardiovascular Risk factors, and Functional status for Institutionalized Elderly Women (동기강화 프로그램이 노년기 여성의 건강행위, 심혈관질환 위험요인 및 기능적 건강상태에 미치는 영향)

  • 송라윤;전경자;노유자;김춘길
    • Journal of Korean Academy of Nursing
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    • v.31 no.5
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    • pp.858-870
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    • 2001
  • Purpose: This study was to compare changes in health behaviors, motivational factors, cardiovascular risk factors, and functional status (SIP) after implementing the 6-month motivation-enhancing program to institutionalized elderly women. Methods: Sixty-four elderly women participated. Face to face interviews with blood sampling and anthropometric assessment were conducted at the pretest, 10 weeks and 6 months during the program. Results: 1. The program participants showed significantly better health behaviors over 6 months. The mean motivational level was also significantly improved, especially for perceived benefits, perceived barriers, and emotional salience. 2. The mean of cardiovascular risk factors for the participants was 21.8 at the level of low to moderate risk. After completing the program, total risk score was significantly decreased to 18.7 at 10 weeks, and further to 17.7 at 6 months. A significant reduction was also found in HDL and LDL-cholesterol levels, blood pressure, obesity, inactivity, and stress. 3. The functional status (SIP) was 11% at the baseline and significantly changed in positive direction at 10 weeks(M=9.3) and at 6 month(M=6.3). The significant improvement was also found in physical and psychosocial dimensions and sleep/rest dimension. Conclusion: The motivation enhancing program was effective to reduce cardiovascular risks and to improve the functional status of institutionalized elderly women by motivating them to perform better health behaviors.

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Cardiovascular Disease Risk according to Socioeconomic Factors among Low-income Midlife Women (사회경제적 요인에 따른 지역사회 저소득층 중년여성의 심혈관질환 위험요인 차이)

  • Ham, Ok-Kyung;Kim, Bong-Jung;Lee, Young-Ah
    • Journal of Korean Public Health Nursing
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    • v.22 no.1
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    • pp.27-38
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    • 2008
  • Purpose: To determine the degree of cardiovascular disease risk according to socioeconomic factors among midlife women in the community and thereby provide baseline data for the development of health promotion programs. Method: A total of 200 women participated in health screenings and a health survey. The survey was performed in November and December, 2006. The survey instruments included socioeconomic factors, health behavior (smoking and exercise), and family history. Biophysical measurement included BMI and blood pressure. Blood samples were drawn for glucose and total cholesterol tests. Results: The mean age was 52.5 years, 34.0% had received education less than 6 years, 70.0% earned a monthly income of less than \1,500,000, and 61.5% were homemakers. Cardiovascular disease risk was significantly different by age (BMI, systolic BP, and exercise), education (systolic BP), monthly income (T. cholesterol), marital status (smoking), and occupation (exercise). Most women had 2 or 3 cardiovascular disease risks. Older age, lower education, and lower income were significantly associated with increased cardiovascular disease risk. Conclusion: Efforts should be made to decrease the number and severity of cardiovascular disease risk factors for midlife women in the community by developing health promotion programs targeting to modify their cardiovascular disease risk factors.

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A Longitudinal Investigation of the Moderating Effect of Social Support on Job Strain Developing Non-Specific Neck Pain in Office Workers

  • Jun, Deokhoon
    • The Journal of Korean Physical Therapy
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    • v.31 no.4
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    • pp.254-259
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    • 2019
  • Purpose: This study examined the interactions between the job strain and social support in the workplace on the development of workrelated neck pain in office workers. Methods: The participants included 62 office workers without neck pain over the last twelve months. A battery of measures evaluating the potential workplace risk factors in office settings were conducted at the baseline, and at the 12 month incidence of work-related neck pain was reported via monthly questionnaires. Survival analysis evaluated the interaction effect between job strain and social support on the development of work-related neck pain. Results: The incidence of work-related neck pain was 1.91 (95% CI: 1.06 - 3.45) per 100 person months. The interaction effect between job strain and social support found that job strain may increase the risk of developing new work-related neck pain when lower social support existed in the workplace. On the other hand, the adverse effects of job strain on the development of neck pain were not significant when workers had higher social support from their colleagues and supervisors. Conclusion: An investigation of the moderating effects of risk factors on neck pain might reveal the unexplained relationship between the risk factors for the development of neck pain in office workers. Therefore, the interest in prevention plans and treatments should involve a comprehensive understanding of the risk factors at workplace.

Post-polypectomy surveillance: the present and the future

  • Masau Sekiguchi;Takahisa Matsuda;Kinichi Hotta;Yutaka Saito
    • Clinical Endoscopy
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    • v.55 no.4
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    • pp.489-495
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    • 2022
  • An appropriate post-polypectomy surveillance program requires the effectiveness of reducing colorectal cancer and safety. In addition, the post-polypectomy surveillance program should consider the burden of limited medical resource capacity, cost-effectiveness, and patient adherence. In this sense, a risk-stratified surveillance program based on baseline colonoscopy results is ideal. Major international guidelines for post-polypectomy surveillance, such as those from the European Union and the United States, have recommended risk-stratified surveillance programs. Both guidelines have recently been updated to better differentiate between high- and low-risk individuals. In both updated guidelines, more individuals have been downgraded to lower-risk groups that require less frequent or no surveillance. Furthermore, increased attention has been paid to the surveillance of patients who undergo serrated polyp removal. Previous guidelines in Japan did not clearly outline the risk stratification in post-polypectomy surveillance. However, the new colonoscopy screening and surveillance guidelines presented by the Japan Gastroenterological Endoscopy Society include a risk-stratified post-polectomy surveillance program. Further discussion and analysis of unresolved issues in this field, such as the optimal follow-up after the first surveillance, the upper age limit for surveillance, and the ideal method for improving adherence to surveillance guidelines, are warranted.

A study on the Project Performance Measurement Baseline for Clients (발주자를 위한 프로젝트 성과측정기준선 설정 방안에 관한 연구)

  • Ko, Dae-Jun;Choi, Eun-A;Park, Dong-Jin;Lee, Sang-Beom
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • 2008.11a
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    • pp.513-516
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    • 2008
  • The risk in the constructions projects is extremely diverse because there are too many indefinite factors. Therefore, Performance Measurement Baseline(PMB) is needed regularly during the construction process. However, nowdays, the PMB in the constructions projects is for contractors' PMB and Performance Management(PM). Clients have a lot of difficulties to control and manage the projects. Therefore, this paper classifies schedule and cost data of the public apartments houses which is a actual cases into types and then conducts regression analysis and deduces a regression. In addition to this paper establishes the Work Breakdown Structure(WBS) and suggests the PMB for the clients through using that.

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