• Title/Summary/Keyword: baseline model

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Determination of the critical diabetes duration in a streptozotocin-induced diabetic rat calvarial defect model for experimentation regarding bone regeneration

  • Kim, Hyun Ju;Jung, Bo Hyun;Yoo, Ki-Yeon;Han, Jin-Woo;Um, Heung-Sik;Chang, Beom-Seok;Lee, Jae-Kwan
    • Journal of Periodontal and Implant Science
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    • v.47 no.5
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    • pp.339-350
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    • 2017
  • Purpose: The purpose of this study was to determine the critical diabetes duration in a streptozotocin (STZ)-induced diabetic rat calvarial defect model for experimentation regarding bone regeneration by evaluating the association between diabetes duration and bone healing capacity through histological and radiographic analyses. Methods: Experimental diabetes was induced in 50 of 60 rats by an STZ injection. The rats were divided into 5 groups, including a control group (group 1), according to diabetes durations of 0, 2, 4, 6, and 8 weeks, respectively. Eighteen rats survived: 4 in group 1, 4 in group 2, 4 in group 3, 5 in group 4, and 1 in group 5. Calvarial defects were created at 0, 2, 4, 6, and 8 weeks after STZ injection in groups 1-5. Cone-beam computed tomography scanning was performed at baseline and at 5 and 7 weeks after surgery. The rats were sacrificed 7 weeks after surgery, followed by histological evaluation. Results: The voxel gray values (VGVs) of group 1 and group 2 increased, whereas the VGVs of group 3 and group 4 decreased starting 5 weeks after surgery, although this trend did not reach statistical significance between groups. On the reconstructed 3-dimensional images and based on an analysis of histological features, groups 1 and 2 showed apparent bone regeneration, while groups 3-5 showed very limited bone regeneration. Conclusions: The critical diabetes duration in an STZ-induced diabetic rat calvarial defect model for experimentation regarding bone regeneration was between 2 and 4 weeks. It is suggested that researchers who use STZ-induced diabetic rats wait for more than 2 weeks following diabetes induction before placing implants or conducting bone regeneration studies to allow definite disturbances in bone healing to emerge.

Improvement of GPS Relative Positioning Accuracy by Using Crustal Deformation Model in the Korean Peninsula (GPS상대측위 정확도 향상을 위한 한반도 지각변동모델 개발)

  • Cho, Jae-Myoung;Yun, Hong-Sik;Lee, Mi-Ran
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.29 no.3
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    • pp.237-247
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    • 2011
  • As of 2011, 72 Permanent GPS Stations are installed to control DGPS reference points by the National Geographic Information Institute in South Korea. As the center of the Earth's mass continues to move, the coordinates of the permanent GPS stations become inconsistent over time. Thus, a reference frame using a set of coordinates and their velocities of a global network of stations at a specific period has been used to solve the inconsistency. However, the relative movement of the permanent GPS stations can lower the accuracy of GPS relative positioning. In this research, we first analyzed the data collected daily during the past 30 months at the 40 permanent GPS stations within South Korea and the 5 IGS permanent GPS stations around the Korean Peninsula using a global network adjustment. We then calculated the absolute and relative amount of movement of the GPS permanent stations. We also identified the optimum renewal period of the permanent GPS stations considering the accuracy of relative GPS surveying. Finally, we developed a Korean a Korean crustal movement model that can be used to improvement of accuracy.

A Plan for Establishing IOT-based Building Maintenance Platform (S-LCC): Focusing a Concept Model on the Function Configuration and Practical Use of Measurement Data (IOT 기반 건축물 유지관리 플랫폼 구축(S-LCC) 방안 : 기능구성과 계측 데이터 활용을 위한 개념 모델을 중심으로)

  • Park, Tae-Keun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.2
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    • pp.611-618
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    • 2020
  • The reliability of the results of LCC analysis is determined by accurate analytical procedures and energy data from which the uncertainty is removed. Until now, systems that can automatically measure these energy data and produce databases have not been commercialized. Therefore this paper proposes a concept model of an S-LCC platform that can automatically collect and analyze electric energy consumption data of equipment systems using the IOT, which is the core tool in the Fourth Industrial Revolution and operates the equipment system efficiently using the analyzed results. The proposed concept model was developed by the convergence of existing BLCS and IOT and was comprised of five modules: Facility Control Module, LCC Analysis Module, Energy Consumption Control Module, Efficiency Analysis Module, and Maintenance Standard Reestablishment Module. Using the results of LCC analysis deduced from this system, the deterioration condition of an equipment system can be identified in real-time. The results can be used as the baseline data to re-establish standards for the maintenance factor, replacement frequency, and lifetime of existing equipment, and establish new maintenance standards for new equipment. If the S-LCC platform is established, it would increase the reliability of LCC analysis, reduce the labor force for entering data and improve accuracy, and would also change disregarded data into big data with high potential.

PM2.5 Simulations for the Seoul Metropolitan Area: (III) Application of the Modeled and Observed PM2.5 Ratio on the Contribution Estimation (수도권 초미세먼지 농도모사: (III) 관측농도 대비 모사농도 비율 적용에 따른 기여도 변화 검토)

  • Bae, Changhan;Yoo, Chul;Kim, Byeong-Uk;Kim, Hyun Cheol;Kim, Soontae
    • Journal of Korean Society for Atmospheric Environment
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    • v.33 no.5
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    • pp.445-457
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    • 2017
  • In this study, we developed an approach to better account for uncertainties in estimated contributions from fine particulate matter ($PM_{2.5}$) modeling. Our approach computes a Concentration Correction Factor (CCF) which is a ratio of observed concentrations to baseline model concentrations. We multiply modeled direct contribution estimates with CCF to obtain revised contributions. Overall, the modeling system showed reasonably good performance, correlation coefficient R of 0.82 and normalized mean bias of 2%, although the model underestimated some PM species concentrations. We also noticed that model biases vary seasonally. We compared contribution estimates of major source sectors before and after applying CCFs. We observed that different source sectors showed variable magnitudes of sensitivities to the CCF application. For example, the total primary $PM_{2.5}$ contribution was increased $2.4{\mu}g/m^3$ or 63% after the CCF application. Out of a $2.4{\mu}g/m^3$ increment, line sources and area source made up $1.3{\mu}g/m^3$ and $0.9{\mu}g/m^3$ which is 92% of the total contribution changes. We postulated two major reasons for variations in estimated contributions after the CCF application: (1) monthly variability of unadjusted contributions due to emission source characteristics and (2) physico-chemical differences in environmental conditions that emitted precursors undergo. Since emissions-to-$PM_{2.5}$ concentration conversion rate is an important piece of information to prioritize control strategy, we examined the effects of CCF application on the estimated conversion rates. We found that the application of CCFs can alter the rank of conversion efficiencies of source sectors. Finally, we discussed caveats of our current approach such as no consideration of ion neutralization which warrants further studies.

Analysis of River Levee Failure Mechanism by Piping and Remediation Method Evaluation (파이핑에 의한 하천제방 붕괴 메카니즘 분석 및 대책공법 평가)

  • Kim, Jin-Man;Moon, In-Jong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.3
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    • pp.600-608
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    • 2017
  • The presence of piping in a levee body allows water seepage to occur by producing a large cavity or water tunnel within it, ultimately resulting in the failure of the river levee and differential settlement. In order to properly cope with river levee failure due to piping and establish a proper remediation method for this problem, it is necessary to analyze the failure mechanism of the river levee due to piping. Therefore, this study analyzed the shape and mechanism of river levee failure due to piping through small-scale and large-scale models and evaluated the seepage pressure distribution characteristics in the hydraulic well, which has been suggested as a remediation method for piping. According to the results of this study, as the safety factor for the piping in the river levee decreased, the river levee failure shape was more clearly shown through the small-scale model test. In the large-scale model test, the type of local damage to the levee due to the piping was identified and the evaluation showed that the hydraulic well had the largest effect on the inhibition of piping below the center of the well. A follow-up study is needed to confirm the reliability of the results. However, it is thought that this study can be utilized as the baseline data for research into the piping-induced river levee failure mechanism and for the preparation of a remediation method.

A statistical analysis of the fat mass repeated measures data using mixed model (혼합모형을 이용한 체지방 반복측정자료에 대한 통계적 분석)

  • Jo, Jinnam;Chang, Un Jae
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.2
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    • pp.303-310
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    • 2013
  • Forty two female students whose fat mass ratio was over 30% were participated in the experiment of fat mass loss of two treatments for 8 weeks. They kept diary for foods they ate every day, took a picture of the foods, transmitted the picture to the experimenter by the camera phone. Among those, 28 students took the picture by regular camera phone (Treatment A), and the other students used smart phone (Treatment B). Fat mass weight and its related variables had been measured repeatedly four times at an interval of two weeks during 8 weeks. It was shown from mixed model analysis of repeated measurements data that AR(1) covariance matrix was selected as the optimal covariance matrix pattern. The correlation between two successive times is highly correlated as 0.838. Based upon the AR(1) covariance matrix structure, the students using smart phones were somewhat more effective in losing fat mass weight than the students using regular camera phones. The time effect was highly significant, but the treatment-time interaction effect was insignificant. The baseline effect and total cholesterol were found to be significant, but the calories with taking foods were somewhat significant, but the waist to hip ratio was found to be insignificant.

Measurement and Evaluation of Thermal Expansion Coefficients of Micrometer-Sized SiO2 Particle-Reinforced Epoxy Composites (마이크로미터 크기 실리카 입자로 강화된 에폭시 복합재료의 열팽창계수 측정 및 평가)

  • Jo, Hyu Sang;Kang, Hee Yong;Lee, Gyo Woo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.39 no.2
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    • pp.129-135
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    • 2015
  • In this experimental study, the thermal stability values of micrometer-sized silica particle-reinforced epoxy composite specimens were evaluated by measuring their thermal expansion coefficients and Young's moduli. For all specimens used in this study (from the baseline specimen to that containing 70 wt% silica filler), the thermal expansion coefficients and Young's moduli were gradually reduced down to 25% and increased up to 51%, respectively. The results of the experiment were compared with those of certain empirical models. The experimental results of the measurement of thermal expansion coefficients corresponded well with those of Kerner's model, which considers the bulk and shear moduli of the matrix and silica filler. However, the results of the measurement of Young's moduli using the empirical Mori-Tanaka model were observed to match better with those of the experiment. The comparison of the results of the experiment with those of the empirical models demonstrated that a reliable model for measuring the thermal expansion coefficients and Young's moduli of composite specimens needs to consider certain property variations in the composites in addition to volume fraction changes in the filler and matrix.

Grain Yield Response of CERES-Barley Adjusted for Domestic Cultivars to the Simultaneous Changes in Temperature, Precipitation, and CO2 Concentration (기온, 강수량, 이산화탄소농도 변화에 따른 CERES-Barley 국내품종의 종실수량 반응)

  • Kim, Dae-Jun;Roh, Jae-Hwan;Yun, Jin I.
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.15 no.4
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    • pp.312-319
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    • 2013
  • Our understanding of the sensitivities of crop responses to changes in carbon dioxide, temperature, and water is limited, which makes it difficult to fully utilize crop models in assessing the impact of climate change on future agricultural production. Genetic coefficients of CERES-Barley model for major domestic cultivars in South Korea (Olbori at Suwon, Albori at Milyang, Saessalbori at Iksan, and Samdobori at Jinju) were estimated from the observed data for daily weather and field trials for more than 10 years by using GenCalc in DSSAT. Data from 1997-2002 annual crop status report (Rural Development Administration, RDA) were used to validate the crop coefficients. The sitecalibrated CERES-Barley model was used to perform crop growth simulation with the 99 treatments of step change combinations in temperature, precipitation and carbon dioxide concentration with respect to the baseline climate (1981-2010) at four sites. The upper boundary corresponds to the 2071-2100 climate outlook from the RCP 8.5 scenario. The response surface of grain yield showed a distinct pattern of model behavior under the combined change in environmental variables. The simulated grain yield was most sensitive to $CO_2$ concentration, least sensitive to precipitation, and showing a variable response to temperature depending on cultivar. The emulated impacts of response surfaces are expected to facilitate assessment of projected climate impacts on a given cultivar in South Korea.

Hydrogeological characteristics of the LILW disposal site (처분부지의 수리지질 특성)

  • Kim, Kyung-Su;Kim, Chun-Soo;Bae, Dae-Seok;Ji, Sung-Hoon;Yoon, Si-Tae
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.6 no.4
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    • pp.245-255
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    • 2008
  • Korea Hydro and Nuclear Power Company(KHNP) conducted site investigations for a low and intermediate-level nuclear waste repository in the Gyeong Ju site. The site characterization work constitutes a description of the site, its regional setting and the current state of the geosphere and biosphere. The main objectives of hydogeological investigation aimed to understand the hydrogeological setting and conditions of the site, and to provide the input parameters for safety evaluation. The hydogeological characterization of the site was performed from the results of surface based investigations, i.e geological mapping and analysis, drilling works and hydraulic testing, and geophysical survey and interpretation. The hydro-structural model based on the hydrogeological characterization consists of one-Hydraulic Soil Domain, three-Hydraulic Rock Domains and five-Hydraulic Conductor Domains. The hydrogeological framework and the hydraulic values provided for each hydraulic unit over a relevant scale were used as the baseline for the conceptualization and interpretation of flow modeling. The current hydrogeological characteristics based on the surface based investigation include some uncertainties resulted from the basic assumption of investigation methods and field data. Therefore, the reassessment of hydrostructure model and hydraulic properties based on the field data obtained during the construction is necessitated for a final hydrogeological characterization.

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Influencing Factors for Compliance Intention of Information Security Policy (정보보안 정책 준수 의도에 대한 영향요인)

  • Kim, Sang-Hoon;Park, Sun-Young
    • The Journal of Society for e-Business Studies
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    • v.16 no.4
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    • pp.33-51
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    • 2011
  • This research derived the influencing factors for employees' compliance with the information security policy in organizations on the basis of Neutralization Theory, Theory of Planned Behavior and Protection Motivation Theory. To empirically analyze the research model and the hypotheses, data were collected by conducting web survey, 194 of 207 questionnaires were available. The test of causal model was conducted by PLS. Reliability, validity and model fit were found to be statistically significant. the results of hypotheses tests showed that seven ones of eight hypotheses could be accepted. The theoretical implications of this study are as follows : 1) this study is expected to play a role of baseline for future research about employee compliance with the information security policy, 2) this study attempted interdisciplinary approach through combining psychology and information system security research, and 3) it suggested concrete operational definitions of influencing factors for information security policy compliance through comprehensive theoretical review. Also, this study has some practical implications. First, it can provide the guideline to support the successful execution of the strategic establishment for implement of information system security policies in organizations. Second, it is proved that the need for conducting education and training program suppressing employees. neutralization psychology to violate information security policy should be emphasized in the organizations.