• 제목/요약/키워드: balanced incomplete block design

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$3{\times}2$ 교차설계법에서 생물학적 동등성 시험의 통계분석 (Statistical Analysis of Bioequivalence Study in $3{\times}2$ Crossover Design)

  • 박상규;김정일;채성산;고승곤;오현숙;양완연;김동섭;최영욱
    • Journal of Pharmaceutical Investigation
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    • 제28권4호
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    • pp.231-239
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    • 1998
  • A $3{\times}2$ crossover design is considered for the bioequivalence of two test formulations with a control. It could be considered as a better choice over $3{\times}3$ crossover design because of the cost and experimental duration. Oh et al.(1998) derived $3{\times}2$ crossover design and discussed its benefits over the typical crossover designs. We consider here the statistical models for $3{\times}2$ crossover design and show its statistical properties. The statistical procedures for the bioequivalence in $3{\times}2$ crossover design are shown through an example and the results are summarized by satisfying the 3 standards that proposed by the Korea Food and Drug Administration Guidelines for Bioequivalence.

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부하균형을 위한 부하상태 전파 알고리즘 (An Algorithm for sending Workload Information in Distributed Load Balancing)

  • 이옥빈;김성열;정일용;이상호
    • 한국멀티미디어학회:학술대회논문집
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    • 한국멀티미디어학회 2002년도 춘계학술발표논문집(하)
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    • pp.1012-1016
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    • 2002
  • 분산시스템에서 부하균형을 유지하기 위해서는 네트워크상의 각 노드는 다른 노드들의 부하상태정보를 가져야만 한다. 네트워크상에 ν개의 노드가 존재할 때 모든 노드간에 부하상태정보를 교환하기 위해서는 Ο(ν²)의 트래픽 오버헤드가 필요하게 된다. 이 논문에서는 분산된 노드간에 동기적으로 동작하는 부하균형 알고리즘을 제시한다. 이를 위해 먼저 SBIBD(symmetric balanced incomplete block design)에 근거하여 (ν,k,1)-configuration에 의해 ν=k²-k+1개의 노드를 갖는 네트워크 토폴로지를 구성하였다. 이 망에서 동작하도록 고안된 부하상태정보 전파 알고리즘은 (equation omitted)의 메시지 오버헤드를 가지면서 각각의 노드가 ν개의 모든 노드에 대한 부하상태정보를 가지도록 한다. 또한 이 부하균형 알고리즘은 모든 링크가 부하상태정보 전송을 위해 동일한 트래픽을 갖도록 설계되었다.

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처리(處理)와 대조(對照)의 비교(比較)를 위(爲)한 군분할(群分割) 가능(可能)한 처리계획(處理計劃)의 생성계획(生成計劃)에 대(對)한 최소원비성(最小圓備性)의 연구(硏究) (Minimal Complete Class of Generator Designs of Group Divisible Treatment Designs for Comparing Treatments with a Control)

  • 김광훈;이우선
    • Journal of the Korean Data and Information Science Society
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    • 제3권1호
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    • pp.47-63
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    • 1992
  • Bechhofer and Tamhane(1981) proposed Balanced Treatment Incomplete Block (BTIB) desings for comparing p test treatments with a control treatment in blocks of size ${\kappa}$. Notz and Tamhane(1983) solved the problem about determination of the minimal complete class for ${\kappa}=3$. However there are a number of design parameters for which BTIB designs do not exist. We suggest a new class of designs called Group Divisible Treatment Desings(GDTD's) that is a larger class including BTIB designs as a subclass. In this paper we give the minimal complete classes of generator designs for GDTD's with ${\kappa}=2,\;p{\geq}4(except\;prime\;number)\;and\;{\kappa}=3,\;p=4(2)6$.

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컨조인트 분석에서 효율적인 문항 설계 (Efficient designs in conjoint analysis)

  • 정종희;임용빈
    • 품질경영학회지
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    • 제46권1호
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    • pp.27-38
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    • 2018
  • Purpose: A large number of attributes with mixed levels are often considered in the conjoint analysis. In the cases where attributes have two or three levels, we research on the efficient design of survey questionnaire to estimate all the main effect and two factor interaction effects with a reasonable size of it. Methods: To reduce the number of questions in a questionnaire, the balanced incomplete block mixed level factorial design with minimum aberration was proposed by Lim and Chung (2016). Based on the number of questions and that of the respondents in that design, D-optimality criterion is adopted to find efficient designs where the main effect and two factor interaction effects are estimated. Results: The list of the number of questions and that of the respondents in efficient designs for survey questionnaire are recommended based on the D-efficiency of each design and the proposed selection criteria for the number of both questions and the respondents. By analyzing all the respondents survey data generated by the simulation study, we find the proper model. Conclusion: The proposed methods of designing survey questionnaires seem to perform well in the sense that how often the proper model is found in a simulation study where all the respondents survey data are generated by the simulation model.

컨조인트 분석에서 실용적인 설계, 분석 및 컨셉 최적화 (Practical Designs, Analysis and Concepts Optimization in Conjoint Analysis)

  • 임용빈;정종희;김주혜
    • 응용통계연구
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    • 제28권5호
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    • pp.951-963
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    • 2015
  • 마케팅 분야에서 활용되는 컨조인트 분석은 속성들간의 시너지 효과 혹은 적대적(상충적)인 효과의 존재 여부를 파악하는데 관심이 있다. 즉, 속성들의 모든 주효과와 이인자 교호작용효과의 크기 추정에 관심이 많다. 본 연구에서는 해상도가 V인 균형된 불완전 블록 일부요인설계를 이용함으로써 속성들의 모든 주효과와 이인자 교호작용효과들을 추정 가능하게 하는 설문지 문항의 설계 방법에 관해서 연구를 한다. 전체 응답자들에 대한 설문지 문항들의 총 묶음으로 구성된 설문지 자료를 분석하여 핵심적인 소수 효과들을 선별하고, 유의한 속성효과들로 표현된 적절한 모형을 찾은 다음에, 효율적인 컨셉 최적화를 수행한다.

DCT 블록의 멀티미디어 핑거프린팅 (Multimedia Fingerprinting in DCT Block)

  • 이강현
    • 전기전자학회논문지
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    • 제15권3호
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    • pp.241-247
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    • 2011
  • 본 논문에서는 DCT 블럭에서 실행되는 멀티미디어 핑거프린팅 알고리즘을 구현한다. 제안된 알고리즘은 DRM의 한계성을 개선하고, 콘텐츠 제공자의 워터마킹과 콘텐츠 사용자의 핑거프린팅을 분리 수행함으로써 위조 및 변조된 콘텐츠의 부정자를 판단하는 책임경계를 결정할 수 있다. 콘텐츠 제공자의 $128{\times}128$ 영상에서 블록크기 $8{\times}8$에 워터마킹 삽입강도 ${\Theta}$는 0.5~1.2까지 적용하여 PSNR은 Inf~46.6dB로 측정되었으며, 콘텐츠 사용자는 블록크기 64 픽셀 범위 내에서 BIBD 기반 코드길이가 l=7,15,31,64를 사용자의 수 n=7,15,31,63에 따라 핑거프린팅 코드길이 또한 l=7,15,31,63으로 PSNR은 Inf~46.1로 측정되었다. 위조 및 변조된 콘텐츠의 부정자 추적은 n-1까지 확장되어 추적율은 1에 접근 되었다.

실험계획의 시각화 (Visualization for Experimental Designs)

  • 장대흥
    • 응용통계연구
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    • 제24권5호
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    • pp.893-904
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    • 2011
  • 실험계획법의 강의내용은 크게 두 개의 파트인 실험계획과 모형분석으로 대별되는데 시각화 작업은 주로 모형분석 중심으로 이루어져 왔다. 실험계획법의 강의내용에 대한 시각화 작업의 일환으로 우리는 실험계획의 시각화를 라틴 방격법의 시각화, 초포화계획법의 시각화, 불완비블럭계획법의 시각화로 나누어 고려하여 볼 수 있다. 실험계획을 시각화하는 작업을 위하여 우리는 계획그림을 제안 할 수 있고 기존의 산점도나 산점도행렬을 사용할 수 있다. 이러한 실험계획의 시각화를 통하여 우리는 이론 중심의 실험계획법 강의에 그림들을 삽입함으로써 실험계획법 수업에서의 시너지효과를 얻을 수 있다.

2차원 광부호분할 다중접속 시스템에 의한 영상의 병렬 전송과 복원법 (Parallel Transmission and Recovery Methods of Images Using the Two Dimensional Fiber-Optic Code-Division Multiple-Access System)

  • 이태훈;박영재;서익수;박진배
    • 대한전기학회논문지:시스템및제어부문D
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    • 제49권12호
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    • pp.683-689
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    • 2000
  • Two-dimensional(2-D) fiber-optic code-division multiple-access(FO-CDMA) system utilizes the optical orthogonal signature pattern code(OOSPC) to encode and decode 2-D data. Encoded 2-D data are spatially multiplexed and transmitted through an image fiber and receiver recovers the intended data by means of thresholding process. OOSPC's construction methods based on expansion of the optical orthogonal code, which is used in one-dimensional(1-D) FO-CDMA system, are introduced. Each OOSPC's performances are compared by using the bit error rate(BER) of interfering OOSPC's of other users. From the results we verify that a balanced incomplete block design(BIBD) construction has the best performance among other mehtods. We also propose a decomposed bit-plane method for parallel transmission and recovery of 256 gray-scale images using OOSPC's constructed by the BIBD method. The simulation result encourages the feasibility of parallel transmission and recovery of multiuser's images.

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Methane Emission, Nutrient Digestibility, Energy Metabolism and Blood Metabolites in Dairy Cows Fed Silages with and without Galacto-oligosaccharides Supplementation

  • Santoso, B.;Kume, S.;Nonaka, K.;Kimura, K.;Mizukoshi, H.;Gamo, Y.;Takahashi, J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제16권4호
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    • pp.534-540
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    • 2003
  • This study was conducted to investigate the effect of supplementation of galacto-oligosaccharides (GOS) on methane emission, nutrient digestibility, energy utilization and blood metabolites by Holstein cows fed silages. In two sequential digestion and respiratory trials, two non-lactating Holstein cows were arranged to a balanced incomplete block design. Experimental diets consisted of two silage types; orchardgrass (Dactylis glomerata L.) based silage (OS), mixed silage (orchardgrass based silage and alfalfa (Medicago sativa L.) silage) (MS), while two GOS levels were without supplementation (0) and 2% of dry matter intake supplementation (2). Four combination diets were OS-0, OS-2, MS-0 and MS-2. Significant effects of silage types and GOS supplementation levels were not observed for DM and OM intake. Whereas the digestibility of OM, NDF and ADF was significantly (p<0.05) higher in cows fed OS with and without GOS compared cows fed MS diets. As percentage of GE intake, fecal energy loss for OS diets was significantly (p<0.05) declined than for MS diets. In contrast, cows fed MS diets had lower (p<0.05) urine energy loss as a proportion of GE intake compared to OS diets. Energy loss as CH4 and heat production was numerically increased when cows fed both OS and MS with GOS supplementation. Compared to OS, CH4 emission in cows fed MS was numerically decreased by 10.8 %. Methane conversion ratio (energy loss as CH4 per unit of GE intake) for OS-0, OS-2, MS-0 and MS-2 were 7.1, 7.2, 6.8 and 7.0, respectively. Plasma of glucose and urea-N concentration were significantly (p<0.05) elevated from 1 h to 6 h after feeding, otherwise total protein in plasma was declined (p<0.01) at 6 after feeding.

Influence of β 1-4 Galacto-oligosaccharides Supplementation on Nitrogen Utilization, Rumen Fermentation, and Microbial Nitrogen Supply in Dairy Cows Fed Silage

  • Santoso, B.;Kume, S.;Nonaka, K.;Gamo, Y.;Kimura, K.;Takahashi, J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제16권8호
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    • pp.1137-1142
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    • 2003
  • In a balanced incomplete block design, two dry Holstein cows were used to investigate the effect of $\beta$ 1-4 galactooligosaccharides (GOS) supplementation on nitrogen (N) utilization, rumen fermentation and microbial N supply in the rumen. During the experiment, cows were fed four diets: orchardgrass (Dactylis glomerata L.) silage (OS), OS with GOS supplementation (OSG), OS mixed with alfalfa (Medicago sativa L.) silage (MS) and MS with GOS supplementation (MSG). GOS was supplemented at 2% of dry matter intake. Diets were fed at maintenance level of protein and energy. Results showed that N digestion was affected by silage and interaction of silage and GOS supplementation. Cows fed OSG had the highest N digested (p<0.05) followed by MS, OS and MSG. Supplementation of GOS to OS or MS diets tended to improve N utilization through reducing the N losses on dairy cows. There was no effect of GOS supplementation on rumen fermentation parameters (i.e. pH, $NH_3$-N and total VFA) at 1 h and 6 h after feeding. Compared to cows fed MS, cows fed OS silage had higher (p<0.05) allantoin excretion (80.8 vs. 67.1 mmol/d) and higher (p<0.05) total purine derivatives excretion (92.9 vs. 78.5 mmol/d). The microbial N supply in cows fed OSG was higher (p<0.05) than those fed OS, MS and MSG.