• Title/Summary/Keyword: background test

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Reliability of Stool Antigen Tests: Investigation of the Diagnostic Value of a New Immunochromatographic Helicobacter pylori Approach in Dyspeptic Patients

  • Korkmaz, Huseyin;Findik, Duygu;Ugurluoglu, Ceyha;Terzi, Yuksel
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.657-660
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    • 2015
  • Background: A diagnosis of H. pylori infection can be made by invasive or non-invasive methods. Several noninvasive diagnostic tests based on the detection of H. pylori stool antigen (HpSA) have been developed. The Genx H. pylori stool antigen card test is a new rapid, non-invasive test that is based on monoclonal immunochromatographic assay. The aim of this study was to determine its sensitivity, specificity, and diagnostic accuracy for diagnosing H. pylori infection in adult patients. Materials and Methods: A total of 162 patients were included in the study. A gastric biopsy was collected for histopathology and rapid urease testing. Stool specimens for HpSA testing were also collected. Patients were considered H. pylori positive if two invasive tests (histological and rapid urease tests) were positive. Results: Using the reference test, 50.6% of the samples were positive for H. pylori infection. The Genx H. pylori antigen test was positive in 19.7% of patients. The sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of the Genx H. pylori antigen test were 51.6%, 96.0%, 88.8%, 76.1%, and 79.0%, respectively. Conclusions: The Genx H. pylori stool antigen card test is a new non-invasive method that is fast and simple to perform but provides less reliable results.

A Study on Accelerated Life Evaluation Method of Component for Automatic Transmission (자동변속기 구성품의 가속수명평가 방법에 관한 연구)

  • Lim, Hongsoo;Cho, Byungchul;Kim, Yunkyoo;Lee, Heeyong;Kim, Jaehoon
    • Transactions of the Korean Society of Automotive Engineers
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    • v.25 no.2
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    • pp.250-256
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    • 2017
  • Automatic transmission(A/T) is one of a car's core components. The durability of A/T has an effect on the durability of the car. The input shaft of A/T passes the power directly from the engine, so the durability of the input shaft for A/T is likewise vital. In this study, the test method of the input shaft is considered and the load spectrum of A/T is analyzed to secure durability of the input shaft. The shape parameter, T-N curve of the input shaft torsional fatigue test are obtained for life evaluation and analysis. Results of this study can be used to get the basic background of the durability test for A/T components.

Application of Digital Image Correlations (DIC) Technique on Geotechnical Reduced-Scale Model Tests

  • Tong, Bao;Yoo, Chungsik
    • Journal of the Korean Geosynthetics Society
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    • v.21 no.1
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    • pp.33-48
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    • 2022
  • This paper presents illustrative examples of the application of advanced digital image correlation (DIC) technology in the geotechnical laboratory tests, such as shallow footing test, trapdoor test, retaining wall test, and wide width tensile test on geogrid. The theoretical background of the DIC technique is first introduced together with fundamental equations. Relevant reduced-scale model tests were then performed using standard sand while applying the DIC technique to capture the movement of target materials during tests. A number of different approaches were tried to obtain optimized images that allow efficient tracking of material speckles based on the DIC technique. In order to increase the trackability of soil particles, a mix of dyed and regular sand was used during the model tests while specially devised painted speckles were applied to the geogrid. A series of images taken during tests were automatically processed and analyzed using software named VIC-2D that automatically generates displacements and strains. The soil deformation field and associated failure patterns obtained from the DIC technique for each test were found to compare fairly well with the theoretical ones. Also shown is that the DIC technique can also general strains appropriate to the wide width tensile test on geogrid, It is demonstrated in this study that the advanced DIC technique can be effectively used in monitoring the deformation and strain field during a reduced-scale geotechnical model laboratory test.

Can tailored home-delivered meal services alleviate self-rated frailty of the low-income older adults in Korea?

  • Junghyun Kim;Hyeja Chang
    • Nutrition Research and Practice
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    • v.17 no.5
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    • pp.1007-1018
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    • 2023
  • BACKGROUND/OBJECTIVES: This study aimed to examine whether the tailored home-delivered meal (HDM) services included nutrition counseling impacts alleviating self-rated frailty among low-income older adults in Korea. SUBJECTS/METHODS: Pre- and post-test were implemented on May 27 and on November 25 in 2019 during 3 weeks, respectively, before and after the 6 months intervention program. Participants completed a questionnaire measuring frailty, malnutrition, food security, depression, and underlying diseases. Initially, 136 older adults were selected as participants for this study, they were recipients of a free meal program from 2 senior welfare centers in Seoul, the final sample size of those who completed the intervention program was 117 (female 70.9%, male 29.1%). Statistical analyses were conducted with IBM SPSS package program, paired t-test and χ2 test to validate the test. RESULTS: There were statistically significant differences in the score of the Tilburg Frailty Indicator (TFI) before and after receiving the tailored HDM services (pre-test 9.46, post-test 2.8, P < 0.01). The differences in the score of TFI by 3 risk groups at the pre-test decreased as a result of receiving these services. CONCLUSIONS: The tailored HDM services alleviated the self-rated frailty of low-income older adults with limited mobility in a community setting. Based on the positive outcomes this study could be applied to developing social services for aging in place.

Reduced Ovarian Cancer Incidence in Women Exposed to Low Dose Ionizing Background Radiation or Radiation to the Ovaries after Treatment for Breast Cancer or Rectosigmoid Cancer

  • Lehrer, Steven;Green, Sheryl;Rosenzweig, Kenneth E
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2979-2982
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    • 2016
  • Background: High dose ionizing radiation can induce ovarian cancer, but the effect of low dose radiation on the development of ovarian cancer has not been extensively studied. We evaluated the effect of low dose radiation and total background radiation, and the radiation delivered to the ovaries during the treatment of rectosigmoid cancer and breast cancer on ovarian cancer incidence. Materials and Methods: Background radiation measurements are from Assessment of Variations in Radiation Exposure in the United States, 2011. Ovarian cancer incidence data are from the Centers for Disease Control and Prevention. Standardized incidence ratios (SIR) of ovarian cancer following breast cancer and rectosigmoid cancer are from Surveillance, Epidemiology, and End Results (SEER) data. Obesity data by US state are from the Centers for Disease Control and Prevention. Mean ages of US state populations are from the United States Census Bureau. Results: We calculated standardized incidence ratios (SIR) from Surveillance, Epidemiology, and End Results (SEER) data, which reveal that in 194,042 cases of breast cancer treated with beam radiation, there were 796 cases of ovarian cancer by 120+ months of treatment (0.41%); in 283, 875 cases of breast cancer not treated with radiation, there were 1,531 cases of ovarian cancer by 120+ months (0.54%). The difference in ovarian cancer incidence in the two groups was significant (p < 0.001, two tailed Fisher exact test). The small dose of scattered ovarian radiation (about 3.09 cGy) from beam radiation to the breast appears to have reduced the risk of ovarian cancer by 24%. In 13,099 cases of rectal or rectosigmoid junction cancer treated with beam radiation in the SEER data, there were 20 cases of ovarian cancer by 120+ months of treatment (0.15%). In 33,305 cases of rectal or rectosigmoid junction cancer not treated with radiation, there were 91 cases of ovarian cancer by 120+ months (0.27%). The difference in ovarian cancer incidence in the two groups was significant (p = 0.017, two tailed Fisher exact test). In other words, the beam radiation to rectum and rectosigmoid that also reached the ovaries reduced the risk of ovarian cancer by 44%. In addition, there was a significant inverse relationship between ovarian cancer in white women and radon background radiation (r = - 0.465. p = 0.002) and total background radiation (r = -0.456, p = 0.002). Because increasing age and obesity are risk factors for ovarian cancer, multivariate linear regression was performed. The inverse relationship between ovarian cancer incidence and radon background was significant (${\beta}=-0.463$, p = 0.002) but unrelated to age (${\beta}=-0.080$, p = 0.570) or obesity (${\beta}=-0.180$, p = 0.208). Conclusions: The reduction of ovarian cancer risk following low dose radiation may be the result of radiation hormesis. Hormesis is a favorable biological response to low toxin exposure. A pollutant or toxin demonstrating hormesis has the opposite effect in small doses as in large doses. In the case of radiation, large doses are carcinogenic. However, lower overall cancer rates are found in U.S. states with high impact radiation. Moreover, there is reduced lung cancer incidence in high radiation background US states where nuclear weapons testing was done. Women at increased risk of ovarian cancer have two choices. They may be closely followed (surveillance) or undergo immediate prophylactic bilateral salpingo-oophorectomy. However, the efficacy of surveillance is questionable. Bilateral salpingo-oophorectomy is considered preferable, although it carries the risk of surgical complications. The data analysis above suggests that low-dose pelvic irradiation might be a good third choice to reduce ovarian cancer risk. Further studies would be worthwhile to establish the lowest optimum radiation dose.

Clinical significance of saccade test, smooth pursuit test, and optokinetic nystagmus test in nystagmography (안진검사에서 단속운동검사, 시추적검사, 시운동성 안진검사의 임상적 의의)

  • Choi, Yoon Seok;Na, Hyung Gyun;Song, Si-Youn;Kim, Yong-Dae;Bae, Chang Hoon
    • Journal of Yeungnam Medical Science
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    • v.34 no.1
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    • pp.29-36
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    • 2017
  • Background: Saccade test, smooth pursuit test, and optokinetic nystagmus test are clinically useful tests to accurately diagnose vertigo. However, there have only been a few studies regarding a correlation between the anatomical site of the lesion and the abnormality of eyeball movement in patients with vertigo. Methods: The medical records of 97 patients with vertigo between January 2006 and June 2008 were reviewed retrospectively. We classified many kinds of abnormalities regarding the saccade test, smooth pursuit test and optokinetic nystagmus test into several categories and analyzed the localizing lesion of vertigo. Results: According to the saccade test, both total saccade abnormality (S-total) and slow velocity of saccade (S-type 3) were shown to be significantly higher in the central lesion of vertigo. According to the smooth pursuit test, symmetrical unidirectional smooth pursuit abnormality (SP-type 2) was observed to be significantly higher in the peripheral lesion over vertigo. Moreover, according to the optokinetic nystagmus test, total optokinetic nystagmus abnormalities (OKN-total) were shown to be significantly useful findings in the diagnosis of the central lesion of vertigo. The coexisting abnormalities of all three tests (S+SP+OKN abnormalities) were shown to be significantly higher in the central lesion of vertigo. Conclusion: These results suggest that all these tests, saccade test, smooth pursuit test, and optokinetic nystagmus test, are very useful to distinguish between the central lesion and the peripheral lesion of vertigo. However, these tests are not beneficial in localizing the central lesion of vertigo.

A Petrov-Galerkin Natural Element Method Securing the Numerical Integration Accuracy

  • Cho Jin-Rae;Lee Hong-Woo
    • Journal of Mechanical Science and Technology
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    • v.20 no.1
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    • pp.94-109
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    • 2006
  • An improved meshfree method called the Petrov-Galerkin natural element (PG-NE) method is introduced in order to secure the numerical integration accuracy. As in the Bubnov-Galerkin natural element (BG-NE) method, we use Laplace interpolation function for the trial basis function and Delaunay triangles to define a regular integration background mesh. But, unlike the BG-NE method, the test basis function is differently chosen, based on the Petrov-Galerkin concept, such that its support coincides exactly with a regular integration region in background mesh. Illustrative numerical experiments verify that the present method successfully prevents the numerical accuracy deterioration stemming from the numerical integration error.

Relationship between Parenting Knowledge and Mother-Infant Interaction According to the Mother's Background (어머니의 배경변인에 따른 양육지식과 영아와 상호작용의 관계)

  • Hong, Soon Ohk;Kim, Sung Hae
    • Korean Journal of Child Studies
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    • v.29 no.6
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    • pp.55-71
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    • 2008
  • This study investigated parenting knowledge, interactions between mother and infant, and relationship between mother's parenting knowledge and mother-infant interaction by mothers' demographic variables. Subjects were 311 mothers. Instruments were the Knowledge of Child Development Inventory (Larsen & Juhasz, 1986) and the Assessment Profile for Early Childhood programs (Abbott-Shim & Sibely, 1987). Data were analyzed by t-test and ANOVA. Results showed (1) differences about parenting knowledge by mothers' employment status, age and education level, (2) differences in mother-infant interaction by mothers' age and education level, (3) parenting knowledge about physical development correlated positively with positive interaction, linguistic modeling, and sensitive response knowledge about linguistic and cognitive development had a large effect on positive mother-infant interaction and linguistic modeling.

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Improved Single Channel Speech Enhancement Algorithm Using Adaptive Postfiltering

  • Song, Eunwoo;Kang, Hong-Goo
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2011.07a
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    • pp.122-125
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    • 2011
  • In real environment, background noise exists everywhere and degrades the performance of system. To reduce this distortion, a speech enhancement algorithm can be very useful and variety methods have been proposed. In this paper, we propose a postfilter to improve the performance of optimally modified log-spectral amplitude (OM-LSA) estimator. Proposed algorithm uses the formant postfilter to minimize perceptual distortion caused by background noise. We adjust an emphasizing parameter which is varied by spectral flatness and first reflection coefficient. The performance of the proposed algorithm is evaluated by measuring the log-spectral distance (LSD) and the perceptual evaluation of speech quality (PESQ) score. The test results show the improvement of proposed algorithm compared to conventional OM-LSA.

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Ship Detection Based on Video Using Background Estimation (배경 추정을 이용한 영상기반 선박검출)

  • Kim, Hyun-Tae;Lee, Keun-Hu;Park, Jang-Sik;Yu, Yun-Sik
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2010.10a
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    • pp.271-273
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    • 2010
  • In this paper, we propose ship detection system which is co-operated with AIS by using background estimation based on image processing for on the sea or harbor image extracted from camera. We experiment with on the sea or harbor image extracted from real-time input image from camera. By computer simulation and real world test, the proposed system show more effective to ship monitoring.

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