• Journal of Biomedical Engineering Research
• /
• v.19 no.4
• /
• pp.379-384
• /
• 1998

To measure precisely the blood velocity in the skin microcirculation, we have used time domain correlation (called Cross-Correlation) based on the processing of the backscattered RF signal obtained with a wideband echographic imaging transducer, although it is difficulties of adaptation of the pulsed wave system, because of the data processing in real time and the hardware problem. This dedicated technology based on a 20MHz echographic imaging system has been developed. We present how the experimental data, i.e. the backscattered RF signal, have to be analyzed. After RF lines realignment, stationary echo canceling procedure and correlation level control, a velocity profile has been obtained. In-vitro result show that velocity measurements as low as 0.1mm/sec attainable with a 80${\mu}m$ in axial resolution. We have also validated with in-vivo experimentation on the external ear of a rabbit using B-mode sector scanning image and M-mode image of a custom made 20MHz skin image system. The flow of the "auriculares caudales" vein, a microvessel of 600 m diameter, has been detected and studied. This technique will allow a more precise exploration of circulatory troubles in cutaneous pathologies.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.32 no.1
• /
• pp.17-25
• /
• 2020

In this study, three-dimensional fluid flow analyses have been performed in order to investigate the performance characteristics of a horizontal axis tidal turbine (HATT) by solving three-dimensional Reynolds-averaged Navier-Stokes equations utilizing the shear-stress-transport turbulence model. The computational domain for the flow analysis has been composed of hexahedral grids, and the grid dependency test has been carried out so as to determine the optimum grid size. Performance characteristics of the HATT have been investigated in consideration of the effects of hub nose geometry, inflow angle, and the tower. It has been found that the power output can be enhanced along with an increase of the ratio of the length to the diameter of the turbine nose, and the power of HATT has been reduced by approximately 10% when the primary fluid flow had an inflow angle of 15°. The power output of downstream HATT is found to be lower than that of the upstream HATT by about 1%.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2011.04a
• /
• pp.1-2
• /
• 2011

Hybrid rockets have lately attracted attention as a strong candidate of small, low cost, safe and reliable launch vehicles. A significant topic is that the first commercially sponsored space ship, SpaceShipOne vehicle chose a hybrid rocket. The main factors for the choice were safety of operation, system cost, quick turnaround, and thrust termination. In Japan, five universities including Hokkaido University and three private companies organized "Hybrid Rocket Research Group" from 1998 to 2002. Their main purpose was to downsize the cost and scale of rocket experiments. In 2002, UNISEC (University Space Engineering Consortium) and HASTIC (Hokkaido Aerospace Science and Technology Incubation Center) took over the educational and R&D rocket activities respectively and the research group dissolved. In 2008, JAXA/ISAS and eleven universities formed "Hybrid Rocket Research Working Group" as a subcommittee of the Steering Committee for Space Engineering in ISAS. Their goal is to demonstrate technical feasibility of lowcost and high frequency launches of nano/micro satellites into sun-synchronous orbits. Hybrid rockets use a combination of solid and liquid propellants. Usually the fuel is in a solid phase. A serious problem of hybrid rockets is the low regression rate of the solid fuel. In single port hybrids the low regression rate below 1 mm/s causes large L/D exceeding a hundred and small fuel loading ratio falling below 0.3. Multi-port hybrids are a typical solution to solve this problem. However, this solution is not the mainstream in Japan. Another approach is to use high regression rate fuels. For example, a fuel regression rate of 4 mm/s decreases L/D to around 10 and increases the loading ratio to around 0.75. Liquefying fuels such as paraffins are strong candidates for high regression fuels and subject of active research in Japan too. Nakagawa et al. in Tokai University employed EVA (Ethylene Vinyl Acetate) to modify viscosity of paraffin based fuels and investigated the effect of viscosity on regression rates. Wada et al. in Akita University employed LTP (Low melting ThermoPlastic) as another candidate of liquefying fuels and demonstrated high regression rates comparable to paraffin fuels. Hori et al. in JAXA/ISAS employed glycidylazide-poly(ethylene glycol) (GAP-PEG) copolymers as high regression rate fuels and modified the combustion characteristics by changing the PEG mixing ratio. Regression rate improvement by changing internal ballistics is another stream of research. The author proposed a new fuel configuration named "CAMUI" in 1998. CAMUI comes from an abbreviation of "cascaded multistage impinging-jet" meaning the distinctive flow field. A CAMUI type fuel grain consists of several cylindrical fuel blocks with two ports in axial direction. The port alignment shifts 90 degrees with each other to make jets out of ports impinge on the upstream end face of the downstream fuel block, resulting in intense heat transfer to the fuel. Yuasa et al. in Tokyo Metropolitan University employed swirling injection method and improved regression rates more than three times higher. However, regression rate distribution along the axis is not uniform due to the decay of the swirl strength. Aso et al. in Kyushu University employed multi-swirl injection to solve this problem. Combinations of swirling injection and paraffin based fuel have been tried and some results show very high regression rates exceeding ten times of conventional one. High fuel regression rates by new fuel, new internal ballistics, or combination of them require faster fuel-oxidizer mixing to maintain combustion efficiency. Nakagawa et al. succeeded to improve combustion efficiency of a paraffin-based fuel from 77% to 96% by a baffle plate. Another effective approach some researchers are trying is to use an aft-chamber to increase residence time. Better understanding of the new flow fields is necessary to reveal basic mechanisms of regression enhancement. Yuasa et al. visualized the combustion field in a swirling injection type motor. Nakagawa et al. observed boundary layer combustion of wax-based fuels. To understand detailed flow structures in swirling flow type hybrids, Sawada et al. (Tohoku Univ.), Teramoto et al. (Univ. of Tokyo), Shimada et al. (ISAS), and Tsuboi et al. (Kyushu Inst. Tech.) are trying to simulate the flow field numerically. Main challenges are turbulent reaction, stiffness due to low Mach number flow, fuel regression model, and other non-steady phenomena. Oshima et al. in Hokkaido University simulated CAMUI type flow fields and discussed correspondence relation between regression distribution of a burning surface and the vortex structure over the surface.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.41 no.1
• /
• pp.53-62
• /
• 2017

The forced convection heat transfer performance of a twist-vane spacer grid for a dual-cooled annular fuel assembly was examined experimentally. The twist-vane spacer grid was uniquely designed to enhance mixing inside subchannels and mixing between adjacent subchannels. For testing, a $4{\times}4$ square-arrayed rod bundle with narrow gaps between rods was prepared as the dual-cooled annular fuel assembly to be simulated. The pitch-to-rod diameter ratio of simulated dual-cooled annular fuel assembly was 1.08. The experiments were performed under the following conditions: axial bulk velocity, 1.5 m/s and heat flux, $26kW/m^2$. With regard to the circumferential temperature distribution, the lowest rod-wall temperatures upstream and downstream were measured at the subchannel center and the position toward the tip of twist-vane, respectively. With regard to the axial temperature distribution, behind the twist-vane spacer grid, the rod-wall temperature decreased drastically, and the Nusselt number was enhanced by up to 56 %. The present measured data indicate that the twist-vane spacer grid can effectively improve the forced convection heat transfer in the dual-cooled annular fuel assembly with narrow gaps.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.50 no.1
• /
• pp.1-12
• /
• 2022

Wind tunnel test for a small scale electric ducted fan with a 104mm diameter was conducted to analyze the aerodynamic characteristics when it was used as a propulsion system of tilt-propeller UAV. Experimental conditions were derived from flight conditions of a sub-scaled OPPAV. Forces and moments of the ducted fan model were measured by a 6-axis balance and 3-dimensional wake vectors which could induce an aerodynamic influence in the vehicle were measured by 5-hole probes. Thrust and torque on hover and cruise conditions were measured and analyzed to drive out the operating conditions when it was applied in the sub-scaled OPPAV. On transition conditions, thrust keep its value with tilt angle variation below 40° and increase after that. But, sideforce increase constantly until 75°. The maximum axial velocity in the wake on hover and cruise conditions was around 60m/s and tangential velocity was around 12m/s. The position of the maximum axial velocity and vortex center move off the fan rotation center line as the tilt angle increases.

• The Journal of the Acoustical Society of Korea
• /
• v.42 no.5
• /
• pp.403-411
• /
• 2023

Functional ultrasound imaging, such as elasticity imaging and micro-blood flow Doppler imaging, enhances diagnostic capability by providing useful mechanical and functional information about tissues. However, the implementation of functional ultrasound imaging poses limitations such as the storage of vast amounts of data in Radio Frequency (RF) data acquisition and processing. In this paper, we propose a sub-Nyquist approach that reduces the amount of acquired axial samples for efficient shear-wave elasticity imaging. The proposed method acquires data at a sampling rate one-third lower than the conventional Nyquist sampling rate and tracks shear-wave signals through RF signals reconstructed using band-pass filtering-based interpolation. In this approach, the RF signal is assumed to have a fractional bandwidth of 67 %. To validate the approach, we reconstruct the shear-wave velocity images using shear-wave tracking data obtained by conventional and proposed approaches, and compare the group velocity, contrast-to-noise ratio, and structural similarity index measurement. We qualitatively and quantitatively demonstrate the potential of sub-Nyquist sampling-based shear-wave elasticity imaging, indicating that our approach could be practically useful in three-dimensional shear-wave elasticity imaging, where a massive amount of ultrasound data is required.

• Steel and Composite Structures
• /
• v.46 no.1
• /
• pp.53-73
• /
• 2023

Man-made structure materials like concrete usually contain inclusions. These inclusions affect the mechanical properties of concrete. In this investigation, the influence of inclusion length and inclination angle on three-dimensional failure mechanism of concrete under uniaxial compression were performed using experimental test and numerical simulation. Approach of acoustic emission were jointly used to analyze the damage and fracture process. Besides, by combining the stress-strain behavior, quantitative determination of the thresholds of crack stress were done. concrete specimens with dimensions of 120 mm × 150 mm × 100 mm were provided. One and two holes filled by gypsum are incorporated in concrete samples. To build the inclusion, firstly cylinder steel tube was pre-inserting into the concrete and removing them after the initial hardening of the specimen. Secondly, the gypsum was poured into the holes. Tensile strengths of concrete and gypsum were 2.45 MPa and 1.5 MPa, respectively. The angle bertween inclusions and axial loadind ary from 0 to 90 with increases of 30. The length of inclusion vary from 25 mm to 100 mm with increases of 25 mm. Diameter of the hole was 20 mm. Entirely 20 various models were examined under uniaxial test. Simultaneous with experimental tests, numerical simulation (Particle flow code in two dimension) were carried out on the numerical models containing the inclusions. The numerical model were calibrated firstly by experimental outputs and then failure behavior of models containing inclusions have been investigated. The angle bertween inclusions and axial loadind vary from 0 to 90 with increases of 15. The length of inclusion vary from 25 mm to 100 mm with increases of 25 mm. Entirely 32 various models were examined under uniaxial test. Loading rate was 0.05 mm/sec. The results indicated that when inclusion has occupied 100% of sample thickness, two tensile cracks originated from boundaries of sample and spread parallel to the loading direction until being integrated together. When inclusion has occupied 75% of sample thickness, four tensile cracks originated from boundaries of sample and spread parallel to the loading direction until being integrated together. When inclusions have occupied 50% and 25% of sample thickness, four tensile cracks originated from boundaries of sample and spread parallel to the loading direction until being integrated together. Also the inclusion was failed by one tensile crack. The compressive strength of samples decease with the decreases of the inclusions length, and inclusion angle had some effects on that. Failure of concrete is mostly due to the tensile crack. The behavior of crack, was affected by the inclusion length and inclusion number.

• IMMUNE NETWORK
• /
• v.21 no.6
• /
• pp.43.1-43.14
• /
• 2021

Group 3 innate lymphoid cells (ILC3), which express IL-22 and IL-17A, has been introduced as one of pathologic cells in axial spondyloarthritis (axSpA). Dyslipidaemia should be managed in axSpA patients to reduce cardiovascular disease, and dyslipidaemia promotes inflammation. This study aimed to reveal the role of circulating ILC3 in axSpA and the impact of dyslipidaemia on axSpA pathogenesis. AxSpA patients with or without dyslipidaemia and healthy control were recruited. Peripheral blood samples were collected, and flow cytometry analysis of circulating ILC3 and CD4⁺ T cells was performed. The correlation between Ankylosing Spondylitis Disease Activity Score (ASDAS)-C-reactive protein (CRP) and circulating immune cells was evaluated. The effect of oxidized low-density lipoprotein cholesterol (oxLDL-C) on immune cell differentiation was confirmed. AxSpA human monocytes were cultured with with oxLDL-C, IL-22, or oxLDL-C plus IL-22 to evaluate osteoclastogenesis using tartrate-resistant acid phosphatase (TRAP) staining and real-time quantitative PCR of osteoclast-related gene expression. Total of 34 axSpA patients (13 with dyslipidaemia and 21 without) were included in the analysis. Circulating IL-22⁺ ILC3 and Th17 were significantly elevated in axSpA patients with dyslipidaemia (p=0.001 and p=0.034, respectively), and circulating IL-22⁺ ILC3 significantly correlated with ASDAS-CRP (Rho=0.4198 and p=0.0367). Stimulation with oxLDL-C significantly increased IL-22⁺ ILC3, NKp44^- ILC3, and Th17 cells, and these were reversed by CD36 blocking agent. IL-22 and oxLDL-C increased TRAP⁺ cells and osteoclast-related gene expression. This study suggested potential role of circulating IL-22⁺ ILC3 as biomarker in axSpA. Furthermore, dyslipidaemia augmented IL-22⁺ ILC3 differentiation, and oxLDL-C and IL-22 markedly increased osteoclastogenesis of axSpA.

• Journal of Korean Society of Steel Construction
• /
• v.16 no.2 s.69
• /
• pp.215-224
• /
• 2004

The inelastic lateral-torsional buckling behavior of the beam-columns and the columns was investigated in this paper. The energy method was deployed to study the inelastic buckling behavior of the beam-columns and columns. which requires the iterative solution of a fourth-order eigenproblem. Hitherto, the patterns of residual stress that satisfies the I-section manufacturing in Korea is not available, therefore the pattern of residual stress used in this study is a 'well-known' simplified pattern. The simplified pattern of the residual stresses is incorporated with the flow theory of plasticity to model the inelastic response. Firstly, this study investigates the inelastic lateral-torsional buckling behavior of the I-section beam-columns under a concentric axial compressive force and uniform bending, and the effect of residual stress on the inelastic buckling behavior of beam-columns is studied. The study is then extended to the inelastic buckling of the columns by eliminating a bending moment. These results are compared it with the design method in the Korean Steel Designers Manual (KSDM 1995). This study has found that design method in KSDM (1995) is excessively conservative.

• Journal of the Korean Society of Propulsion Engineers
• /
• v.13 no.3
• /
• pp.41-49
• /
• 2009

The present paper describes a mathematical modeling and simulation of the separation of a solid rocket booster from an air breathing engine vehicle. The vehicle and booster are considered as a multi-connected body and the booster is assumed to move only along the axial direction of the vehicle. The dynamic motion of the vehicle and the booster were modeled by using Kane's method. The aerodynamic forces on the whole system along various positions of booster were calculated by using DATCOM software and the internal pressure force acting on the effective surface during separation was simply calculated with gas dynamics and Taylor MacColl equation. Numerical simulation was done by using Mathworks-Matlab. From the result, the variation of Mach number and angle of attack are not large during the separation, so the variation of pitch angle and the characteristics of inlet flow for varying the Mach number and angle of attack during the separation test can be identified as neglectable values.