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PROPERTIES OF FLUORIDE-RELEASING RESIN COMPOSITE RESTORATIVE MATERIALS (불소방출성 콤포짓트 레진계 수복재의 특성)

  • Kim, Sang-Hoon;Baik, Byeong-Ju;Kim, Jae-Gon;Yang, Yeon-Mi;Park, Jeong-Yeol
    • Journal of the korean academy of Pediatric Dentistry
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    • v.35 no.3
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    • pp.418-426
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    • 2008
  • The objectives of this study were to examine the properties of fluoride-releasing resin composite restorative materials. Four commercially available compomer materials (Compoglass F: CF, $Dyract^{(R)}$ AP: DA, $Dyract^{(R)}$ flow: DF, F2000: FT) and one fluoride-releasing composite resin ($Tetric^{(R)}$ Ceram: TC) were selected as experimental materials. Rectangular-shaped tensile test specimens were fabricated in a teflon mold giving 5mm in gauge length and 2mm in thickness. Disk-shaped specimens were fabricated in the split teflon mold with diameter of 15mm and thickness of 1mm. After curing for an hour, specimens were immersed in deionized water at $37^{\circ}C{\pm}1^{\circ}C$ for 30 days. All specimens were thermocycled for 10,000 cycles with 15 seconds of dwelling time in each $5^{\circ}C$ and $55^{\circ}C$ water baths. Toothbrush abrasion test was conducted under a load of 1.5 N and the abraded surfaces were examined with surface roughness tester (SV-3000, Mitutoyo Co, Japan) and SEM (JSM-5800, JEOL, Japan). Fluoride recharging was done by toothbrushing for 3 min. using a fluoride toothpaste (Perio Alpine Herb, LG Household & Health Care, Korea). The results obtained were summarized as follows; 1. The highest tensile strength value of 32.3 MPa was observed in TC group and the lowest value of 16.8 MPa was observed in CF group. The tensile strength of TC group was significantly higher than those of CF and DF groups (P<0.05). 2. The lowest Ra value of 0.287 was observed in TC group and the highest value of 1.516 was observed in FT group. The Ra value of FT group was significantly higher than other groups (P<0.05). 3. The abraded surfaces revealed the increase of surface roughness due to the protrusion and missing of filler particles. 4. The release of fluoride of compomers after tooth brushing by Perio Alpine Herb was initially large and then followed by small and continuously. But it remains small and constant in fluoride-releasing composite resin of TC. 5. The highest value of fluoride release after toothbrushing by Perio Alpine Herb was $2.064{\mu}g/cm^2$ in CF group and the lowest value was $0.1119{\mu}g/cm^2$ in TC group. The amount of fluoride release of CF group was significantly higher than other groups (P<0.05).

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Usefulness of Low Dose Oral Contrast Media in $^{18}F-FDG$ PET/CT ($^{18}F-FDG$ PET/CT에서 저용량 경구용 조영제의 유용성)

  • An Young-Sil;Yoon Joon-Kee;Hong Seon Pyo;Joh Chul-Woo;Yoon Seok-Nam
    • Nuclear Medicine and Molecular Imaging
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    • v.40 no.5
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    • pp.257-262
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    • 2006
  • Purpose: The standard protocol using large volume of oral contrast media may cause gastrointestinal discomfort and contrast-related artifacts in PET/CT. The aim of this study was to evaluate the usefulness of low dose oral contrast in $^{18}F-FDG$ PET/CT. Materials and Methods: We retrospectively reviewed the whole-body PET/CT images in a total of 435 patients. About 200 ml of oval contrast agent (barium sulfate) was administered immediately before injection of $^{18}F-FDG$. The FDG uptake of intestines was analyzed by visual and semi- quantitative method on transaxial, coronal and saggital planes. Results: Seventy (16%, 113 sites) of 435 images showed high FDG uptake (peak SUV > 4); 50 (74%, 84 sites) with diffuse and 20 (15%, 29 sites) with focal uptake. The most commonly delivered site of oral contrast media was small bowel (n=27, 39%). On PET/CT images, FDG uptake coexisted with oral contrast media in 26 patients (54%, 38 sites) with diffuse pattern and 9 (45%, 9 sites) with focal pattern, and by sites, those were 38 (45%) and 9 (31%), respectively. In small bowel regions, the proportion of coexistence reached as high as 61% (29/47 sites). A visual analysis of available non-attenuation corrected PET images of 27 matched regions revealed no contrast-related artifact. Conclusion: We concluded that the application of low dose contrast media could be helpful in the evaluation of abdominal uptake in the FDG PET/CT image.

Nutrient Utilization, Body Composition and Lactation Performance of First Lactation Bali Cows (Bos sondaicus) on Grass-Legume Based Diets

  • Sukarini, I.A.M.;Sastradipradja, D.;Sutardi, T.;Mahardika, IG.;Budiarta, IG.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.12
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    • pp.1681-1690
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    • 2000
  • A study on energy and protein utilization, and milk production of Bali cows on grass-legume diets was carried out using 12 first lactation cows (initial BW $263.79{\pm}21.66kg$) during a period of 16 weeks starting immediately post calving. The animals were randomly allotted into 4 dietary treatment groups R1, R2, R3 and R4, receiving from the last 2 months of pregnancy onwards, graded improved rations based on a mixture of locally available grass and legume feed ad libitum. R1 contained on a DM basis 70% elephant grass (PP, Penisetum purpureum) plus 30% Gliricidia sepia leaves (GS), R2 was 30% PP plus 55% GS supplemented with 15% Hibiscus tilliactus leaves (HT, defaunating effect), R3 and R4 were 22.5% PP+41.25% GS+11.25% HT+25% concentrate, where R3 was not and R4 supplemented with zinc di-acetate. TDN, CP and zinc contents of the diets were 58.2%, 12.05% and 18.3 mg/kg respectively for R1, 65.05%, 16.9% and 25.6 mg/kg respectively for R2, 66.03%, 16.71% and 29.02 mg/kg respectively for R3 and 66.03%, 16.71% and 60.47 mg/kg respectively for R4. Milk production and body weight were monitored throughout the experimental period. In vivo body composition by the urea space technique validated by the body density method and supported by carcass data was estimated at the start and termination of the experiment. Nutrient balance and rumen performance characteristics were measured during a balance trial of 7 days during the 3rd and 4th week of the lactation period. Results indicated that quality of ration caused improvement of ruminal total VFA concentration, increments being 52 to 65% for R2, R3 and R4 above R1, with increments of acetate being less (31 to 48%) and propionate being proportionally more in comparison to total VFA increments. Similarly, ammonia concentrations increased to 5.24 to 7.07 mM, equivalent to 7.34 to 9.90 mg $NH_3-N/100ml$ rumen fluid. Results also indicated that feed quality did not affect DE and ME intakes, and heat production (HP), but increased GE, UE, energy in milk and total retained energy (RE total) in body tissues and milk. Intake-, digestible- and catabolized-protein, and retained-protein in body tissues and milk (Rprot) were all elevated increasing the quality of ration. Similar results were obtained for milk yield and components with mean values reaching 2.085 kg/d (R4) versus 0.92 kg/d (R1) for milk yield, and 170.22 g/d (R4) vs 71.69 g/d (R1), 105.74 g/d (R4) vs 45.35 g/d (R1), 101.34 g/d (R4) vs 46.36 g/d (R1) for milk-fat, -protein, and -lactose, respectively. Relatively high yields of milk production was maintained longer for R4 as compared to the other treatment groups. There were no significant effects on body mass and components due to lactation. From the relationship $RE_{total}$ (MJ/d)=12.79-0.373 ME (MJ/d); (r=0.73), it was found that $ME_{m}=0.53MJ/kgW^{0.75}.d$. Requirement of energy to support the production of milk, ranging from 0.5 to 3.0 kg/d, follows the equation: Milk Prod. ($Q_{mp}$, kg/d)=[-2.48+4.31 ME($MJ/kg^{0.75}.d$)]; (r=0.6) or $Q_{mp}$=-3.4+[0.08($ME-RE_{body\;tissue}$)]MJ/d]; (r=0.94). The requirement for protein intake for maintenance ($IP_m$) equals $6.19 g/kg^{0.75}.d$ derived from the relationship RP=-47.4+0.12 IP; (r=0.74, n=9). Equation for protein requirement for lactation is $Q_{nl}$=[($Q_{mp}$)(% protein in milk)($I_{mp}$)]/100, where $Q_{nl}$ is g protein required for lactation, $Q_{mp}$ is daily milk yield, Bali cow's milk-protein content av. 5.04%, and $I_{mp}$ is metabolic increment for milk production ($ME_{lakt}/ME_{m}=1.46$).

Ecological Characteristics of Rhodotypos scandens Habitat in Imsil-gun, Jeollabuk-do, Korea (전라북도 임실군 병아리꽃나무 자생지의 생태적 특성)

  • Park, Kyung-Uk;Beon, Mu-Sup;Oh, Hyun-Kyung;You, Ju-Han
    • Journal of Environmental Impact Assessment
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    • v.24 no.4
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    • pp.352-366
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    • 2015
  • The purpose of this study is to offer the basic data to the habitat conservation and management by surveying and analysing the ecological characteristics such as the flora, vegetation structure and soil of Rhodotypos scandens habitat. The flora were summarized as 131 taxa including 57 families, 99 genera, 107 species, 1 subspecies, 17 varieties and 6 forms. The life forms grouped as in the follows; the megaphanerophytes(MM) were 21 taxa, 24 taxa of the microphanerophytes(M), 30 taxa of nanophanerophytes(N), 6 taxa of chamaiphytes(Ch), 20 taxa of hemicryptophytes(H), 17 taxa of geophytes(G), 12 taxa of therophytes(Th) and 1 taxa of hydrophytes(HH). The present conditions of communities were 8 types including Zelkova serrata, Quercus aliena, Ulmus parvifolia, Rhamnella frangulioides, Castanea crenata, Albizia julibrissin, Celtis sinensis and Robinia pseudoacacia. In case of the dominant species by layers, the tree layer species were Zelkova serrata, Quercus aliena, Ulmus parvifolia, Castanea crenata, Albizia julibrissin, Celtis sinensis and Robinia pseudoacacia, and the subtree layer species were Rhamnella frangulioides, Q. aliena, Z. serrata, A. julibrissin, U. parvifolia and Broussonetia kazinoki. The shrub layer species was Rhodotypos scandens. In the results of analyzing the diversity index, $H^{\prime}{_{max}}$ from 1.691 to 2.610, from 2.197 to 3.466 in H'max, from 0.646 to 0.903 in J' and from 0.097 to 0.354 in D. In the results of analysing the soil, there showed that acidity was 5.6, 0.5dS/m of electrical conductivity(EC), 59.1mg/kg of available $P_2O_5$, 49.7% of organic matter content, $0.4cmol^+/kg$ of exchangeable $K^+$, $13.5cmol^+/kg$ of exchangeable $Ca^{2+}$, $3.3cmol^+/kg$ of exchangeable $Mg^{2+}$.

Characteristics of Phosphorus Accumulation in Organic Farming Fields (유기농업실천농가 포장내 인산의 분포특성)

  • Kim, Pil-Joo;Lee, Sang-Min;Yoon, Hong-Bae;Park, Yang-Ho;Lee, Ju-Young;Kim, Suk-Chul;Choe, Suk-Chul
    • Korean Journal of Soil Science and Fertilizer
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    • v.33 no.4
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    • pp.234-241
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    • 2000
  • Organic farming (OF) is regarded as alternative farming types against general farming system for sustainable agriculture, recently. However, there is little information on effects of OF on soil properties and watershed condition. In order to determine the effects of OF on soil properties, 36, 10 and 8 sites of organic farming (OF) fields of plastic film houses, paddy and orchard were selected in the national scale, respectively, to evaluate their chemical properties and phosphorus distributing characteristics. The average organic matter (OM) contents in organic farming fields were with $44g\;kg^{-1}$ in plastic film houses, $26g\;kg^{-1}$ in paddies and $39g\;kg^{-1}$ in orchard soils higher than the average OM contents in conventional farming (CF) soils. Available phosphates were accumulated to 986 in plastic film house soils and $754mg\;kg^{-1}$ in orchard soils, respectively, over the optimum range. Furthermore, total P (T-P) reached to $2.973mg\;kg^{-1}$ in plastic film houses and $2303mg\;kg^{-1}$ in orchards in OF soils. It could be attained by applying repeatedly low N/P ratio of manure-based compost. In two types of soils inorganic P was dominant with the ratio of 62~80% of T-P, and then residual and organic Ps followed. However. residual-P was dominant in paddy soils with the rate of 50% of T-P. Fractionation of soil extractable P showed that Ca-P was dominant with about $1,330mg\;kg^{-1}$ in upland soils in OF fields, which is affected by high soil pH of over 6.0. However. Fe-P of extractable P was dominant in paddy soils. Water-soluble P was very high with 65 and $26mg\;kg^{-1}$ in plastic film house and orchard soils in OF. From this results. OF regarded as an environment-friendly farming system may cause serious soil deterioration by accumulated phosphorus and may also cause water pollution.

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High Strength Slaughter Wastewater Treatment in a Novel Combined System of Hybrid-Rotating Biological Contactor and Biological Aerated Filter (Hybrid-RBC와 BAF의 조합공정을 이용한 고농도 도축폐수의 처리 특성)

  • Jung, Chan-Il;Ahn, Jo-Hwan;Bae, Woo-Keun;Kim, Seung-Jin
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.2
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    • pp.77-84
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    • 2011
  • This study was conducted to develop a novel combined system of a hybrid rotating biological contactor (RBC) process that was composed of an attached- and suspended- biomass reactor, followed by a settler and a biological aerated filter (BAF) column to treat a high strength slaughter wastewater. Long term influences of organic and nitrogen loading rates were investigated to see how the combined system worked in terms of the removal efficiency. A synthetic wastewater containing a pork cutlet steak source (commercially available) and swine blood was used to feed the combined system. The hybrid RBC process showed excellent removals: about 95% for soluble COD and 85% for ammonium nitrogen. However, the unsettled solids seriously deteriorated the removal efficiency of total COD (TCOD) and total nitrogen (TN) in the RBC process. A significant fraction of the TCOD and suspended solids (SS) was further removed in the BAF column although the effluent quality was still unsatisfactory, giving TCOD 300 mg/L, SS 180 mg/L and TN 59 mg/L. An addition of polyaluminium chloride into the RBC effluent improved the performance of the settler and BAF, producing an excellent quality of final effluent; TCOD 16.5 mg/L, SS 0 mg/L, TN 55.5 mg/L, TP 1.3 mg/L. Therefore, it was confirmed that the combined system of hybrid RBC and BAF could treat a high strength slaughter wastewater excellently.

Effects of Expeller Cake Fertilizer on Soil Properties and Tah Tasai Chinese Cabbage Yield in Organic Greenhouse Farm (유기농 시설하우스 토양에서 유박 시용이 토양특성 및 다채 생육에 미치는 영향)

  • Kim, Kab-Cheol;Ahn, Byung-Koo;Ko, Do-Young;Kim, Ju;Jeong, Seong-Soo
    • Korean Journal of Environmental Agriculture
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    • v.33 no.3
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    • pp.149-154
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    • 2014
  • BACKGROUND: To evaluate the application level of expeller cake fertilizer(ECF), we have investigated soil chemical properties, leaf mineral contents and yield of tah tasai Chinese cabbage in a plastic film greenhouse. METHODS AND RESULTS: Five levels of fertilizer were applied as 0%(ECF 0), 50%(ECF 50), 75%(ECF 75), 100% (ECF 100) and 150%(ECF 150) by base 1,848 kg/ha of ECF. In 2012, tah tasai Chinese cabbage was planted on April 28 in a silt loam soil and harvested on July 12. Commercial yields were measured 10 times from May 10 to July 12. Electrical conductivity (2.24~3.09 dS/m), available $P_2O_5$(484~581 mg/kg) and exchangeable cations($K^+$, $Ca^{2+}$ and $Mg^{2+}$) were tended to increase by the application of ECF. However, the range of those was not significant. The contents of T-N, K, Ca and P of tah tasai Chinese cabbage leaves were 62.2~66.5 g/kg, 44.3~48.7 g/kg, 5.1~5.9 g/kg and 5.6~6.2 g/kg, respectively. The nitrogen utilization rate of tah tasai Chinese cabbage was 39.4~51.6%, and it was decreased with increased application amount of ECF. The yield of tah tasai Chinese cabbage was 9,806 to 12,730 kg/ha on the basis of application amount of ECF and it was not increased in spite of increased ECF. CONCLUSION: The optimum dose of application of ECF for cultivation of tah tasai Chinese cabbage was ranged from 924 kg/ha(as ECF 50) to 1,386 kg/ha(as ECF 75). Environment-friendly and economical amount of applied fertilizer is more important than yield for cultivation of tah tasai Chinese cabbage.

Inverse Agonists at $A_1$ Adenosine Receptors in Rat Cerebral Cortex (흰쥐의 뇌의$A_1$ 아데노신 수용체에 작용하는 역효현제에 관한 연구)

  • Park, Kyung-Sun;Yang, Wan-Suk;Kim, Kyung-Hwan
    • The Korean Journal of Pharmacology
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    • v.32 no.1
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    • pp.23-29
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    • 1996
  • According to the traditional receptor model, competitive antagonists share with agonists the ability to bind to a common site on receptors, but they are different from agonist in that they cannot trigger the biological response-i.e., they lack intrinsic efficacy. Recent findings extend the model by indicating that not all antagonists display an intrinsic efficacy of zero but that some display 'inverse agonism'. In the present study we studied the inverse agonism at $A_1$ adenosine receptors in membranes prepared from rat cerebral cortex. Eight commercially available $A_1$ adenosine receptor antagonists (CGS-15943, ADPX, CPT, DPCPX, DPX, N-0840, PACPX and 8-PT) were screened for inverse agonism by measuring the extent of $[^{35}S]guanosine-5'-({\gamma}-thio)$ triphosphate $([^{35}S]GTP_{\gamma}S)$ binding to G proteins. The agonist-induced stimulation of $[^{35}S]GTP_{\gamma}S$ bindings was completely blocked in the presence of $A_1$ adenosine receptor antagonists. Under optimal conditions, two types of antagonists could be distinguished. Seven antagonists including DPCPX decreased the basal $[^{35}S]GTP_{\gamma}S$ binding in the absence of agonist, displaying inverse agonist activity. One (CGS-15943) had no effect on the basal bindings. N-ethylmaleimide treatment reduced the basal bindings as well as agonist-mediated stimulation of $[^{35}S]GTP_{\gamma}S$ bindings, indicating that a substantial amount of this binding reflects an activated state of the C proteins. In good agreement with these findings, 0.1 mM GTP decreased the apparent affinity of the receptors for the agonist PIA, increased that for DPCPX, and had no effect on that for CGS-15943.

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Are Bound Residues a Solution for Soil Decontamination\ulcorner

  • Bollag, Jean-Marc
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2003.10a
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    • pp.111-124
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    • 2003
  • Processes that cause immobilization of contaminants in soil are of great environmental importance because they may lead to a considerable reduction in the bioavailability of contaminants and they may restrict their leaching into groundwater. Previous investigations demonstrated that pollutants can be bound to soil constituents by either chemical or physical interactions. From an environmental point of view, chemical interactions are preferred, because they frequently lead to the formation of strong covalent bonds that are difficult to disrupt by microbial activity or chemical treatments. Humic substances resulting from lignin decomposition appear to be the major binding ligands involved in the incorporation of contaminants into the soil matrix through stable chemical linkages. Chemical bonds may be formed through oxidative coupling reactions catalyzed either biologically by polyphenol oxidases and peroxidases, or abiotically by certain clays and metal oxides. These naturally occurring processes are believed to result in the detoxification of contaminants. While indigenous enzymes are usually not likely to provide satisfactory decontamination of polluted sites, amending soil with enzymes derived from specific microbial cultures or plant materials may enhance incorporation processes. The catalytic effect of enzymes was evaluated by determining the extent of contaminants binding to humic material, and - whenever possible - by structural analyses of the resulting complexes. Previous research on xenobiotic immobilization was mostly based on the application of $^{14}$ C-labeled contaminants and radiocounting. Several recent studies demonstrated, however, that the evaluation of binding can be better achieved by applying $^{13}$ C-, $^{15}$ N- or $^{19}$ F-labeled xenobiotics in combination with $^{13}$ C-, $^{15}$ N- or $^{19}$ F-NMR spectroscopy. The rationale behind the NMR approach was that any binding-related modification in the initial arrangement of the labeled atoms automatically induced changes in the position of the corresponding signals in the NMR spectra. The delocalization of the signals exhibited a high degree of specificity, indicating whether or not covalent binding had occurred and, if so, what type of covalent bond had been formed. The results obtained confirmed the view that binding of contaminants to soil organic matter has important environmental consequences. In particular, now it is more evident than ever that as a result of binding, (a) the amount of contaminants available to interact with the biota is reduced; (b) the complexed products are less toxic than their parent compounds; and (c) groundwater pollution is reduced because of restricted contaminant mobility.

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Harmonization of Hemolysis Index in Clinical Chemistry Laboratory and Its Application as a Result Verification Tool (화학검사 결과의 검증을 위한 용혈 지수 일치화 도구 개발)

  • Pyo, Sang Shin;Nam, Hyun Su;Cha, Young Jong;Lee, Seungkwan;Lee, Hae Kyung
    • Korean Journal of Clinical Laboratory Science
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    • v.49 no.4
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    • pp.350-358
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    • 2017
  • The hemolysis index (HI) is semi-quantitative marker for hemolysis. Because the characteristics of the HI vary from one commercial platform to another, no standardization or harmonization of the HI is currently available. Specimens (N=40) randomly selected from clinical patients were artificially hemolyzed in vitro. The serum of the specimens was then diluted with a 20 mg/dL difference between 0~300 mg/dL based on serum hemoglobin measured using the XE-2100 hematology automation equipment (Sysmex, Japan). Diluted serum was measured using the Hitachi-7600 biochemical automation equipment (Hitachi, Japan) to differentiate between HI and serum hemoglobin. The data showed linearity between HI and serum hemoglobin and that HI 1 contained approximately 20 mg/dL of serum hemoglobin. To determine the blood rejection threshold, the HI was divided into three groups: HI 0~1, HI 4~6, HI 9~15. After another batch of clinical specimens (N=40) was measured using a Hitachi-7600 (Hitachi, Japan), each specimen was moved forward and backward with the piston of the syringe to induce an artificial in vitro hemolysis, then measured again with a Hitachi-7600 (Hitachi, Japan). The percentage difference between the three groups was analyzed by ANOVA or the Kruskal-Wallis test. In the post-test, there were significant differences between the HI 0~1 and the HI 5~6: Glucose, creatinine, total protein, AST, direct bilirubin, uric acid, phosphorus, triglyceride, LDH, CPK, Magnesium, and potassium levels. Because many clinical tests differed significantly, the threshold for hemolysis could be appropriate for HI 5 (serum hemoglobin 100 mg/dL).