• BMB Reports
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• v.36 no.1
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• pp.43-48
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• 2003

Understanding the process of carcinogenesis will involve both the accumulation of many scientific facts derived from molecular, biochemical, cellular, physiological, whole animal experiments and epidemiological studies, as well as from conceptual understanding as to how to order and integrate those facts. From decades of cancer research, a number of the "hallmarks of cancer" have been identified, as well as their attendant concepts, including oncogenes, tumor suppressor genes, cell cycle biochemistry, hypotheses of metastasis, angiogenesis, etc. While all these "hallmarks" are well known, two important concepts, with their associated scientific observations, have been generally ignored by many in the cancer research field. The objective of the short review is to highlight the concept of the role of human adult pluri-potent stem cells as "target cells" for the carcinogenic process and the concept of the role of gap junctional intercellular communication in the multi-stage, multi-mechanism process of carcinogenesis. With these two concepts, an attempt has been made to integrate the other well-known concepts, such as the multi-stage, multi-mechanisn or the "initiation/promotion/progression" hypothesis; the stem cell theory of carcinogenesis; the oncogene/tumor suppression theory and the mutation/epigenetic theories of carcinogenesis. This new "integrative" theory tries to explain the well-known "hallmarks" of cancers, including the observation that cancer cells lack either heterologous or homologous gap junctional intercellular communication whereas normal human adult stem cells do not have expressed or functional gap junctional intercellular communication. On the other hand, their normal differentiated, non-stem cell derivatives do express connexins and express gap junctional intercellular communication during their differentiation. Examination of the roles of chemical tumor promoters, oncogenes, connexin knock-out mice and roles of genetically-engineered tumor and normal cells with connexin and anti-sense connexin genes, respectively, seems to provide evidence which is consistent with the roles of both stem cells and gap junctional communication playing a major role in carcinogenesis. The integrative hypothesis provides new strategies for chemoprevention and chemotherapy which focuses on modulating connexin gene expression or gap junctional intercellular communication in the premalignant and malignant cells, respectively.

• Journal of the Korean Society of Food Culture
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• v.12 no.1
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• pp.87-96
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• 1997

The purpose of this study is, to examine current foodservice management practices at free meal service organization for elderly people and, to evaluate the attitude of recipients about the service and their ecological background. 6 meal service center as well as randomly selected 120 recipients at Sungnam area were surveyed and interviewed and result were summarized as follow. The cost of each meal (lunch) was ranged from 1,300 won to 1,500 won and number of attendant at meal service were ranged from 50 to 200 persons. Meal time for lunch begins from 10:30 am to noon because greater portion of people (elderly) didn't take breakfast frequently. Most of the center adapted self-service system. Standard recipe was not developed and meal preparation was controlled under the experiences of volunteer’s. Recording system of, nutrition management, production control, storage and inventory control was not well adapted by most of the center. In order to measure the level of storage, sanitation etc., scorin system in survey was adapted in this study and result are as follow: The score of sanitation of kitchen was lower than dinning area and that of food storage was lowest score. It was suggested that not only financial but also systematical support on management by local government may be necessary to meet the goal of supply nutritionally balanced food at the center. The score given by the recipient on the satisfaction of meal service was rate as 4.8 at the 5-point maximum scale. Meeting friends and share social relationship was major reason (41.6% of the total) of visiting to the center. It is suggested that in order to meet the changes of the patterns of change of social and family structure, the service of the center should be extended in urban area and it is necessary to develop systematic management models for the center.

• The Journal of Korean Physical Therapy
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• v.17 no.1
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• pp.1-26
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• 2005

The most of patients and protectors point that the Home Visting Physical Therapy is necessary and compulsive. A Public Health Center and a Welfare Center have to help a home visiter for treatment cure to ask for professional medical services in general hospital. On getting a name lists of patients a treatment of doctors, they must remark the conditions of the patients to keep the mutual relation general hospital. A home visiting physical therapists in the welfare center and public health center need to discuss a main doctors in a same center for revaluation of patients. The system in a general hospital consists of the medical department and the administration with the doctor of hospital as the central figure. A department of home visiting physical therapy has a physical therapy team closely connected with various medical office in hospital. The system in a public health center is composed of the health executive office, health direction medicine office, and the community health office. Department of home visiting physical therapy belongs to community health office. Home visiting physical therapy in a welfare center belongs to home visiting service office. The qualifications of a physical therapist is intended for people who have received clinic experience of three years and regular education. The theory (352 hours) and practice (248 hours) total to 600 hours. They can develop professional skills through these education courses. The frequency of home visiting is proper third a week after talking with a medical attendant about the state of patient. The care time is proper from 30 to 60 minutes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.2 no.2
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• pp.81-89
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• 2001

Space systems are operating in a changing and uncertain space environment and are desired to have autonomous capability for long periods of time without frequent telecommunications from the ground station At the same time. requirements for new set of projects/systems calling for ""autonomous"" operations for long unattended periods of time are emerging. Since, by the nature of space systems, it is desired that they perform their mission flawlessly and also it is of extreme importance to have fault-tolerant sensor/actuator sub-systems for the purpose of validating science measurement data for the mission success. Technology innovations attendant on autonomous data validation and health monitoring are articulated for a growing class of autonomous operations of space systems. The greatest need is on focus research effort to the development of a new class of fault-tolerant space systems such as attitude actuators and sensors as well as validation of measurement data from scientific instruments. The characterization for the next step in evolving the existing control processes to an autonomous posture is to embed intelligence into actively control. modify parameters and select sensor/actuator subsystems based on statistical parameters of the measurement errors in real-time. This research focuses on the identification/demonstration of critical technology innovations that will be applied to Autonomous Spacecraft Health Monitoring/Data Validation Control Systems (ASHMDVCS). Systems (ASHMDVCS).

• The Journal of the Korea Contents Association
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• v.14 no.1
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• pp.466-477
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• 2014

This research aims to analyze the importance-performance among airline selection attributes using foreign tourists. For this purpose, data were collected from Japanese and Chinese tourists to Korea. Of the various airline selection attributes, four factors were deduced that includes: transport service, accompany service, cabin service and basic service using exploratory factor analysis. This study estimated how important airline selection attributes are and how much are they performed. Also, this study analyzed the ranking among each selection attributes using T-test. The importance-performance analysis showed 'Concentrate Here' in quadrant I, 'Keep up the Good Work' in quadrant II, 'Low Priority' in quadrant III and 'Possible Overkill' in quadrant IV. Quadrant I specifically showed low performance in terms of the following specific attributes: communicative convenience, flight attendant's friendliness, seating preference. As these attributes are deemed significant, airline managers should focus along these areas.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.11 no.1
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• pp.7-18
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• 1993

In analyzing whole surface of non-topographic objects, the design of multi-station photogrammetric network must involve a number of questions such as geometric configuration of exposure stations, imaging geometry, control point configuration or weight allowance of adjustments. Above all, the surveying of the interior of narrow longitudinal structures needs the design of special photogrammetric network. The main objective of this paper is to suggest the schemes for solving difficult problems attendant upon whole inside-surface analysis of structure and to improve the accuracy and reliability of final measurements. For it, the multi-station exposure network suitable to shape and size of the inside of the structure was designed. Then three dimensional data were acquired by bundle adjustments derived from multi-station photos and the effects of network design factors on accuracy of measurements were contemplated. Also, the algorithm for detection of blunders was developed here is expected to lead to improvement of the reliability of photogrammetric solutions.

• Clinical and Experimental Pediatrics
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• v.54 no.4
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• pp.169-175
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• 2011

Purpose: Acute internal hemorrhage is an occasionally life-threatening complication in pediatric cancer patients. Many therapeutic approaches have been used to control bleeding with various degrees of success. In this study, we evaluated the efficacy of selective internal iliac artery embolization for controlling acute intractable bleeding in children with malignancies. Methods: We retrospectively evaluated the cases of 6 children with various malignancies (acute lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, T-cell prolymphocytic leukemia, Langerhans cell histiocytosis, and rhabdomyosarcoma), who had undergone selective arterial embolization (SAE) of the internal iliac artery at the Chonnam National University Hwasun Hospital between January 2004 and December 2009. SAE was performed by an interventional radiologist using Gelfoam$^{(R)}$ and/or Tornado$^{(R)}$ coils. Results: The patients were 5 boys and 1 girl with median age of 6.9 years (range, 0.7-14.8 years) at the time of SAE. SAE was performed once in 4 patients and twice in 2, and the procedure was unilateral in 2 and bilateral in 4. The causes of hemorrhage were as follows: hemorrhagic cystitis (HC) in 3 patients, procedure-related internal iliac artery injuries in 2 patients, and tumor rupture in 1 patient. Initial attempt at conservative management was unsuccessful. Of the 6 patients, 5 (83.3%) showed improvement after SAE without complications. Conclusion: SAE may be a safe and effective procedure for controlling acute intractable hemorrhage in pediatric malignancy patients. This procedure may obviate the need for surgery, which carries an attendant risk of morbidity and mortality in cancer patients with critical conditions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.7204-7213
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• 2014

This study examined the impact on work life on health recognition and health behavior practices. The data was collected from 314 flight attendants from June to July 2014 in A airline. Questionnaires were used to measure the levels of health recognition, health behavior practice, Stress index, external image, and the impact on the work life. The data was analyzed using descriptive statistics, T-test, ANOVA, Pearson's correlation, structural equating model using the SPSS AMOS 18.0 program. The research showed that health care influences the external image and work life, and the health behavior practice influences the stress management. A survey of the various influencing factors of work life will be needed in terms of human resource management to provide quality service to customers, and health care programs for flight attendants in workplace will be needed.

• Journal of the Korean Society of Clothing and Textiles
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• v.29 no.9_10 s.146
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• pp.1265-1273
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• 2005

The objective of this study is to examine the images of the current uniforms and to provide the basic references in designing female flight attendants uniforms. In Incheon International Airlines, 11 of the major airlines with the most passengers along with the highest capacity were chosen and 22 pieces of photographs were collected, two photos coming from each airline companies. The semantic differential scale has been formed by 16 pairs of adjectives. Then, it has conducted a statistical analysis using a SPSS WINDOWS that contains 475 copies of the selected questionnaires (375 of the non-flight attendants, and 100 of the female flight attendants). The following are the results and the conclusion of this study. According to this study, four main components of the uniforms of the female flight attendants were attractiveness, femininity, noticeability, and activity, which have occupied $65.9\%$ of the total variance. It was concluded that attractiveness and femininity were two main factors in perceiving the females' uniforms. According to the results of the uniform image difference, it was shown that Asiana Airline's uniform is the most attractive and Cathay Pacific Airline uniform is the most feminine. The most noticeable uniform was from Singapore airline which included cultural and traditional components of its own national colors. Pants suits of Lufthansa airline and Northwest airline were shown as the most active uniforms. There were significant differences in uniform images according to subjects' gender, age, education, and occupation. Men perceived uniforms more attractive, feminine, and active than women. People over 40 perceived uniforms more attractive, feminine, and active, and the High School graduates perceived uniforms more feminine and active. On occupational basis, Federal workers and Educators perceived uniforms more active on uniforms. Passengers who take planes once a month perceived uniforms more attractive, feminine, and active.

• Journal of Preventive Medicine and Public Health
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• v.21 no.2 s.24
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• pp.442-450
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• 1988

Effects of various factors related to the process of social action of hospital services on the selecting a hospital were investigated by using of questionnaires answered by 1,319 patients in a certain University Hospital, in Chungchongnam-Do, from November, 1986 to November, 1987. The results summarized were as follows ; 1. Each of the examined factors, that is, sincerity of an attendant physician in medical treatment and explaining the condition of a disease, confidence to doctor and nurse, doctor's and nurse's response to calling by patient, kindness of the hospital staffs and food handlers, sanitariness of hospital, cleanness of clothes and bed sheets, hospital foods, and rest surroundings, are not solely decisive to attitude of hospital utilization, but the factors effects compositely on hospital utilization 2. Hospital services of the social action process are more effective to hospital utilization in cases of the hospitalization caused by the traffic facility than for the medical skill and facilities.