• Science of Emotion and Sensibility
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• v.24 no.4
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• pp.117-128
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• 2021

In this work, we study smart gloves that can prevent carpal tunnel syndrome when using a mouse. Because the left and right wrist movements are fine, a tensile fabric sensor with a large gauge factor and low hysteresis was required before the study. A universal testing machine was used to calculate each gauge rate on four different fabrics, and the fabric with the least hysteresis was selected. In addition, three attachment methods were analyzed using Arduino to select a method with a large sensor value change. For prototypes made by attaching to the selected fabric, data patterns were analyzed using Arduino. The first method identifies only one sensor (A sensor), and the second identifies two sensors (A and B sensors). When the wrist is bent to the right, tensile fabric sensors are attached to both the left (A sensor) and right (B sensor) sides of the wrist, the A sensor is strained, increasing the △sensor value, and the B sensor is relaxed, decreasing the △sensor value. However, when the wrist was bent to the left, the pattern was analyzed in the opposite direction. Through this study, we examined smart gloves to prevent carpal tunnel syndrome with an algorithm that turns on the LED when the wrist is bent, and based on the results of this study, we will directly use mice on 10 people to identify problems and solve problems when used.

• Science of Emotion and Sensibility
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• v.25 no.3
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• pp.77-90
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• 2022

This study seeks to develop a stretch sensor for measuring the wrist movements of people using fishing lures. In order to confirm wrist movement, a stretch sensor was attached to the wrist band, and measurements of the dorsiflexion, plantar flexion, and fishing landing motion were measured using a scale to gauge factor, tensile strength, and elongation recovery rate. A conductive sensor using CNT dispersion was developed and applied to the E-band under the same conditions. A total of 15 sensors of the same size and five types of impregnation once, twice, and three times each were used to measure the gauge factor using UTM. The sensor that was impregnated twice had the best gauge rate, and the prototypes were manufactured with three sensors with high gauge rates and tensile strength. The results of the operation test conducted by connecting to the Arduino showed that Sample 1, which had the highest tensile strength and gauge factor, had a stable graph wavelength in three operations. Samples 2 and 3 showed stable wavelengths in the dorsiflexion and the plantar flexion; however, signal noise appeared in the fishing landing motion. This showed stable wavelengths in the two motions, but the wavelengths of the graphs differ depending on the tensile strength and gauge factor in the fishing landing motion. As a result, it was possible to identify the conditions necessary for manufacturing a stretch sensor for measuring wrist movement. This study will contribute to the development of smart wearable products for lure fishing.

• Journal of Life Science
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• v.28 no.4
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• pp.389-397
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• 2018

The structure of glycan residues attached to glycoproteins can influence the biological activity, stability, and safety of pharmaceutical proteins delivered from transgenic pig milk. The production of therapeutic glycoprotein in transgenic livestock animals is limited, as the glycosylation of mammary gland cells and the production of glycoproteins with the desired homogeneous glycoform remain a challenge. The ${\beta}$-1,3-N-acetylglucosaminylatransferase1 (B3GNT1) gene is an important enzyme that attaches N-acetylglucosamine (GlcNAc) to galactose (Gal) residues for protein glycosylation; however, there is limited information about pig glycosyltransferases. Therefore, we cloned the pig B3GNT1 (pB3GNT1) and investigated its functional properties that could attach N-acetylglucosamine to galactose residue. Using several different primers, a partial pB3GNT1 mRNA sequence containing the full open reading frame (ORF) was isolated from liver tissue. The ORF of pB3GNT1 contained 1,248 nucleotides and encoded 415 amino acid residues. Organ-dependent expression of the pB3GNT1 gene was confirmed in various organs from adult and juvenile pigs. The pB3GNT1 mRNA expression level was high in the muscles of the heart and small intestine but was lower in the lungs. For functional characterization of pB3GNT1, we established a stable expression of the pB3GNT1 gene in the porcine kidney cell line (PK-15). As a result, it was suggested that the glycosylation pattern of pB3GNT1 expression in PK-15 cells did not affect the total sialic acid level but increased the poly N-acetyllactosamine level. The results of this study can be used to produce glycoproteins with improved properties and therapeutic potential for the generation of desired glycosylation using transgenic pigs as bioreactors.