• Title/Summary/Keyword: ascites fluid

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Roles for Paraoxonase but not Ceruloplasmin in Peritoneal Washing Fluid in Differential Diagnosis of Gynecologic Pathologies

  • Yildirim, Mustafa;Demirpence, Ozlem;Kaya, Vildan;Suren, Dinc;Karaca, Mehmet;Evliyaoglu, Osman;Yilmaz, Necat;Gunduz, Seyda
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6233-6237
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    • 2014
  • Background: Intraperitoneal spread of gynecologic cancers is a major cause of mortality and morbidity and often presents with malignant ascites. Microscopic tumor spread can be demonstrated by a peritoneal wash cytology and help assess the prognosis of the disease. In our study, the roles of paraoxonase and ceruloplasmin, measured in peritoneal washing fluid of patients operated for gynecologic pathologies in differential diagnosis was investigated. Materials and Methods: Patients operated for malign or benign gynecologic pathologies in Antalya Education and Research Hospital Gynecology Clinic between 2010-2012 were included in the study. Samples were obtained during surgery. Results: A statistically significant difference was detected between patients with benign and malign diseases with regards to PON1 levels measured in peritoneal washing fluid (p:0.044), the average values being $64.2{\pm}30.8$ (Range 10.8-187.2) and $41.4{\pm}21.4$ (Range 10.4-95.5), respectively. No significant variation was evident for ceruloplasmin. Conclusions: Paraoxonase levels measured in peritoneal washing fluid may contribute to the differentiation of malign-benign diseases in gynecologic pathologies.

EFFECT OF RED GINSENG POWDER ON LIPOLYTIC AND ANOREXIGENIC FACTOR (TOXOHORMONE-L) FROM CANCEROUS ASCITES FLUID (암의 복수액에 존재하는 지방분해 및 식욕감퇴 인자에 미치는 고려인삼의 영향)

  • Okuda Hiromichi;Masuno Hiroshi;Lee Song Jae
    • Proceedings of the Ginseng society Conference
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    • 1984.09a
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    • pp.145-152
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    • 1984
  • Toxohormone-L (THL) elicited fatty acid release from rat epididymal adipose tissue, which is present in cancerous ascites fluids. In this study, the effect of ginseng powder on lipolysis induced by Toxohormane-L, and ACTH was studied. Korean ginseng selectively inhibited Toxohormone-L induced lipolysis, but did not inhibit ACTH-induced lipolysis.

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Tricuspid valve dysplasia complicated with pulmonic regurgitation in a Cocker Spaniel dog

  • Nam, So-Jeong;Choi, Ran;Park, In-Chul;Hyun, Changbaig
    • Korean Journal of Veterinary Research
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    • v.48 no.4
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    • pp.481-487
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    • 2008
  • A 17-month-old intact male Cocker Spaniel was presented with primary complaints of severe ascites, exercise intolerance, and diarrhea. Diagnostic studies revealed tricuspid and pulmonic regurgitation on phonocardiogram, right ventricular enlargement on the electrocardiogram, typical right cardiac enlargement signs on the thoracic radiography and tricuspid valve malformation and marked enlargement of the right atrium and right ventricle on the echocardiography and tricuspid and pulmonary regurgitation on the color spectral echocardiography, suggesting tricuspid valve dysplasia and pulmonary hypertension. Using angiography and cardiac catheterization, pulmonary hypertension was ruled out. Further echocardiographic study revealed membranous valvular structures cranial to pulmonary annulus causing pulmonary regurgitation. Based on these findings on the diagnostic investigation, the case was diagnosed as tricuspid valve dysplasia complicated with pulmonic regurgitation. The dog was medically managed with furosemide, enalapril, nitroglycerine transdermal patch and pimobendan after the ascitic fluid removal.

Uterine Rupture with Retained Placenta in a Primiparous Bichon Frise Bitch

  • Park, Jiyoung;Shin, Sang-Tae;Lee, Hae-Beom;Jeong, Seong Mok
    • Journal of Veterinary Clinics
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    • v.34 no.5
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    • pp.374-376
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    • 2017
  • This report describes a case of postpartum uterine rupture associated with retained placenta and sequential acute metritis, not dystocia. A 14-month-old Bichon Frise bitch presented with continuous vaginal bleeding. She delivered five puppies 3 days ago and expelled four placentas on the next day. After then, anorexia, acute depression with continuous vaginal haemorrhage developed. Plain radiography showed decreased serosal detail, and ultrasonography showed irregularly thickened uterine wall and ascites. Blood-tinged peritoneal fluid was an exudate with bacteria. Ovariohysterectomy was curative for the patient, and four full-thickness perforated holes were identified on both sides of the uterine horns.

A T-cell type multicentric Lymphoma affecting central nervous system in a Cocker Spaniel dog

  • Kim, Ju-Won;Jung, Dong-In;Kang, Byeong-Teck;Yoo, Jong-Hyun;Park, Chul;Kim, Dae-Young;Park, Hee-Myung
    • Korean Journal of Veterinary Research
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    • v.48 no.3
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    • pp.363-367
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    • 2008
  • A 4-year-old female Cocker spaniel was presented with respiratory distress and abdominal distension. Pleural effusion, ascites, hepatosplenomegaly, and superficial lymphadenopathy were observed and multicentric lymphoma was diagnosed by cytological examination. Immunophenotyping of lymph node and bone marrow using polymerase chain reaction for antigen receptor rearrangement identified a stage V lymphoma originating from T-cell. Despite of systemic chemotherapy using L-asparagenase, vincristine, cyclophoaphamide and prednisolone, neurologic deficits came out and progressed. Cerebrospinal fluid analysis revealed neoplastic lymphocytic pleocytosis indicating central nervous system involvement of lymphoma. The postmortem diagnosis was confirmed based on the histology and imunohistochemistry.

Inhibitory Effect of Crude Acidic Polysaccharide of Korean Ginseng on Lipolytic Action of Toxohormone-L from Cancerous Ascites Fluid (인삼의 조산성다당체 성분이 암독소호르몬-L의 지방분해 억제작용)

  • 이성동;이광승
    • Journal of Ginseng Research
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    • v.14 no.1
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    • pp.10-13
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    • 1990
  • Effect of an acidic polysaccharide fraction In Korean white and red ginseng on lipolytic action of Toxohormone-L was studied. Crude acidic polysaccharide fraction was extracted from main and lateral root of Korean white and red ginseng separately and purified several times. Inhibitory effect of crude polysaccharide fraction was determined by unit (1 unit is loft inhibition rate per Is sample). Yields of purified crude polysaccharide fraction of main and lateral root of red ginseng were 2.9 and 2.2 times higher than those of white ginseng, respectively. Inhibitory effects of main root of white and red ginseng, 11.hen final reaction concentrations of sample were 50, 100, 200, 500 $\mu$g/ml, were 37.2가 and 23.7% higher than those of lateral root of white and red ginseng. Inhibitory effect of main root of red ginseng was 2.3 times higher than that of white ginseng.

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Successful Management of Post-Attenuation Neurologic Signs and Portal Hypertension in a Dog with Congenital Portoazygos Shunt

  • Jin-Young Kim;Kun-Ho Song;Joong-Hyun Song
    • Journal of Veterinary Clinics
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    • v.41 no.2
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    • pp.95-100
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    • 2024
  • A 6-year-old neutered male Poodle with a body weight of 2.7 kg was diagnosed with a congenital extrahepatic portoazygos shunt presented with progressive hepatic encephalopathy. Five days after surgical attenuation, the patient showed post-attenuation neurological signs (PANS) such as generalized tonic-clonic seizure, dull mentation, and tremor. PANS were successfully managed with antiepileptic drugs, but third-space fluid accumulation (ascites and peripheral edema) and phlebectasia were newly identified, suggesting marked portal hypertension (PHT). Telmisartan, spironolactone, carvedilol, and prednisolone were sequentially administered. Three months after surgery, both abnormal clinicopathological values such as anemia and hypoalbuminemia, and clinical signs completely resolved. Herein, we report successful management strategies for PANS and PHT in a dog following surgical attenuation of a congenital portoazygos shunt.

Septicemia and Navel III Associated with Escherichia coli Infection in a Thoroughbred Foal (더러브렛 자마의 Escherichia coli 제대 감염에 의한 전신 패혈증)

  • Park, Seok-Jun;Jung, Ji-Youl;Lee, Sung-Jae;Bae, Jong-Hee;Kim, Jae-Hoon
    • Journal of Veterinary Clinics
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    • v.24 no.4
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    • pp.636-639
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    • 2007
  • Septicemic polyserositis and navel ill associated with Escherichia coli were reported in a 14-day-old male thoroughbred foal. The horse died after showing 12-day history of anorexia, lethargy, lameness and endophthalmus. Grossly, milky yellow abscesses were occupied in umbilicus, umbilical vein and artery. Large amounts of turbid pale yellow fluids were seen in pericardial sac, thoracic and abdominal cavity. Yellowish fibrinous materials were also presented in thoracic and abdominal cavity. Sticky pale yellow fluid and fibrinous materials were filled in stifle joint cavities of both hind limbs. Histologically, fibrino-purulent polyserositis and arthritis were observed. Severe omphalophlebitis with intra-lesional Gram negative bacterial colonies were noted in umbilical vein. Most of mesothelial cells in serosal cavities were severely hypertrophied. Pathogenic E. coli was purely isolated from ascites, thoracic and synovial fluids. Based on the results, the septicemic polyserositis may be originated from the umbilical cord infected with E. coli in this foal.

Candida albicans Peritonitis After Urethrostomy in a Dog (요도루조성술 후에 개에서 발생한 Candida albicans 복막염)

  • Choi, Joon-Hyuk;Park, Hyung-Jin;Song, Gun-Ho;Seo, Kyoung-Won
    • Journal of Veterinary Clinics
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    • v.30 no.6
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    • pp.473-477
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    • 2013
  • A 7-year-old castrated male Maltese developed anemia, ascites with peritonitis, and vomiting after urethrostomy. A microbial culture test of the peritoneal fluid indicated Candida albicans. Antifungal therapy was administered with intravenous fluconazole combined with antibacterial therapy. The patient recovered completely 37 days after referral admission.

Modulation of Human Macrophage Phagocytic Activity by C-reactive Protein (C 반응성 단백질이 사람 Macrophage 탐식 기능에 미치는 영향)

  • 김용호;강신원
    • Biomedical Science Letters
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    • v.4 no.1
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    • pp.35-42
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    • 1998
  • The effects of CRP purified from human ascites fluid on phagocytic activity of the human macrophage were investigated. CRP was purified using affinity chromatography including absorption on p-diazonium phosphocholine or C-polysaccharide coupled sepharose 4B and gel filtration on hydroxylapatite column chromatography. Macrophage was separated ficoll hypaque gradient density and absorption method, and then was confirmed phagocytic uptake test using latex method. CRP was able either to inhibit or to enhance phagocytic activity of human macrophage against bacteria in vitro. The effects of CRP on phagocytic activity of human macrophage were in time and dose-dependent manners. The additional sequence of reaction mixture against bacteria in vitro shows a threshold stimulus on the activation of phagocytic response upon the CRP.

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