• Title/Summary/Keyword: aromatic

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Recent Research Progress in the Microbial Production of Aromatic Compounds Derived from L-Tryptophan (미생물을 이용한 L-트립토판 유래 방향족 화합물 생산 최근 연구)

  • Lee, Ji-yeong;Lee, Jin-ho
    • Journal of Life Science
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    • v.30 no.10
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    • pp.919-929
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    • 2020

  • Aromatic compounds are widely used in the chemical, food, polymer, cosmetic, and pharmaceutical industries and are produced by mainly chemical synthesis using benzene, toluene, and xylene or by plant extraction methods. Due to many rising threats, including the depletion of fossil fuels, global warming, the strengthening of international environmental regulations, and the excessive harvesting of plant resources, the microbial production of aromatic compounds using renewable biomass is regarded as a promising alternative. By integrating metabolic engineering with synthetic and systems biology, artificial biosynthetic pathways have been reconstituted from L-tryptophan biosynthetic pathway in relevant microorganisms, such as Escherichia coli and Corynebacterium glutamicum, enabling the production of a variety of value-added aromatic compounds, such as 5-hydroxytryptophan, serotonin, melatonin, 7-chloro-L-tryptophan, 7-bromo-L-tryptophan, indigo, indirubin, indole-3-acetic acid, violacein, and dexoyviolacein. In this review, we summarize the characteristics, usage, and biosynthetic pathways of these aromatic compounds and highlight the latest metabolic engineering strategies for the microbial production of aromatic compounds and suitable solution strategies to overcome problems in increasing production titers. It is expected that strain development based on systems metabolic engineering and the optimization of media and bioprocesses using renewable biomass will enable the development of commercially viable technologies for the microbial production of many aromatic compounds.

  • https://doi.org/10.5352/JLS.2020.30.10.919 인용 PDF KSCI HTML

Screening of Resistance Genes Linked to Brown Planthopper Using STS Marker in Aromatic Rice Germplasm

  • Kim, Jeong-Soon;Ahn, Sang-Nag;Hong, Sung-Jun;Park, Jong-Ho;Lee, Min-Ho;Han, Eun-Jung;Damodaran, P.N.;Kim, Yong-Ki;Jee, Hyeong-Jin;Shim, Chang-Ki
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.56 no.2
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    • pp.167-176
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    • 2011

  • Brown planthopper (BPH) is a serious insect pest of rice crop throughout rice growing countries, and yield loss due to its infection can be up to 60%. This study aimed to evaluate efficiency of molecular markers for screening BPH resistance accessions among 86 aromatic rice germplasm Eighty-six accessions of aromatic rice germplasm included two accessions of Tongil type (bred in Korea), 28 accessions of japonica type and 56 accessions of indica type. We applied eight STS markers (pBPH9, pBPH19, pBPH20, pBPH21, AJ09-b, RG457L, RG457B, and 7312.T4A) which were linked to four of BPH resistance genes, Bph1, Bph13(t), Bph10, and Bph18(t) respectively. One japonica type accession, 415XIr352, and six indica type accessions possessed one or four positive bands when tested with four STS markers linked to Bph1 gene. One indica type aromatic rice, Basmati9-93, showed the target bands linked to the Bph10 gene. The other accessions did not show same fragments as the respective resistant lines. Bph13(t) is the most widely introduced resistance gene and only one accession showed positive bands implying that this accession might harbor Bph10 and Bph18(t) genes. Three aromatic accessions, Domsiah, Khao Dawk Mali 105 and 415XIr352 showed gene pyramiding of Bph1 and Bph13(t). Two indica aromatic rice, Ds 20 and Basmati 9-93, possessed at least two BPH resistance genes, Bph1, Bph18(t) and Bph13(t), Bph18(t), respectively. These results indicates that aromatic rice germplasm have narrow diversities of BPR resistance genes.

  • https://doi.org/10.7740/kjcs.2011.56.2.167 인용 PDF KSCI

Aroma Characteristics of Tricholoma matsutake Mushrooms Collected from Eleven Major Sites in Korea (한국(韓國)의 11개(個) 주요(主要) 산지(産地)에서 채집(採集)한 송이(松栮)의 향기성분(香氣成分)에 관(關)한 연구(硏究))

  • Cho, Duck Hyun;Lee, Kyung Joon;Han, Sim Hee
    • Journal of Korean Society of Forest Science
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    • v.88 no.4
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    • pp.490-497
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    • 1999

  • The objectives of this study were to identify aroma characteristics of Tricholoma matsutake(S. Ito et Imai) Sing. growing in different geograghic ranges in South Korea. Mushrooms were collected from 11 major sites which included four sites(Bonghwa, Uljin, Goryung and Chungdo) in Kyongbuk Province, three sites(Changnyung, Hadong and Hamyang) in Kyongnam Province, two sites(Yangyang and Inje) in Kangwon Province, one site(Goisan) in Choongbuk Province, and one site(Namwon) in Chonbuk Province. One of three mushrooms from each site were used for measurements of aromatic characteristics. Aromatic compounds were identified using a dynamic headspace trap method at $40^{\circ}C$ and GC-MSD(gas chromatograph-mass spectrometric detector) method. A total of 25 aromatic compounds were identified. Large variations in the composition and amount of aromatic compounds were noticed. Major aroma compound was 1-octen-3-ol, while methyl cinnamate known as the major aroma compound in matsutake was not detected at all. The total amount of aromatic compounds was highest in Bonghwa, and decreased in the order of Chungdo, Inje, Hamyang, Uljin, and Yangyang. Based on the total amount, kinds and amounts of individual aromatic compounds, the mushrooms from 11 major sites were grouped into following four types : 1) Bongwha Type : the total amount of aromatic compounds was highest, with major compound being 3-methyl 1-butanol. 2) Hamyang Type including Chungdo, Yangyang and Inje : 1-octen-3-of comprised 2/3 of total aromatic compounds, with second major being 3-methyl butanal. 3) Uljin Type : 1-octen-3-ol comprised 94% of total aromatic compounds, with other compounds being almost nothing. 4) Goisan Type including Goryung, Namwon, Changnyung, and Hadong : the total amount of aromatic compounds was lower than other three types.

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PHOTOCHEMICAL REACTIONS OF AROMATIC $\alpha$-DIKETONES

  • Kim, Sung Sik
    • Journal of Photoscience
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    • v.1 no.2
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    • pp.123-126
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    • 1994

  • Irradiation of aromatic $\alpha$-diketones, such as benzil, 4,4'-dimethylbenzil, 4-chlorobenzil, 4,4'-diisopropylbenzil, 3,3,'-dimethylbenzil, in methanol gives rise to xanthone derivatives, in addition to $\alpha$-hydroxyketones. Irradiation of 4,4'-dibromobenzil, 2,2'-pyridil, 2,2'-naphthil and 9,9'-anthril yields only $\alpha$-hydroxyketones, whereas 4,4'-dimethoxybenzil yields methyl 4-methoxybenzoate.

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