• 과학기술학연구
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• 제19권2호
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• pp.207-249
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• 2019

이 논문은 올림픽 전산시스템 개발과정을 추적하면서 공식 역사서술 이면의 다이나믹스를 보이는 것을 기본 목적으로 한다. 서울올림픽 개최가 결정된 직후 정부는 앞선 올림픽에서 사용된 전산시스템을 도입하겠다고 구상했다. 이에 KAIST 전산개발센터 과학기술자들은 독자적 개발의 당위성을 설득하는 데 큰 노력을 기울였으며, 전국체전에서 무사히 작동되는 전산시스템을 개발함으로써 충분한 개발 능력을 갖추었음을 증명해야 했다. 올림픽 전산시스템 개발을 구체화하면서 주관부처, 참여 기관, 연구자 사이에 다양한 논쟁이 발생했고, 결과적으로 최종 산물은 단일한 하나의 시스템이 아니라 여러 기관이 개발한 각기 다른 네 개의 시스템이 결합한 모듈형으로 귀착되었다. 이 때문에 "장외금메달"이라는 호평을 받았지만, 어느 기관도 올림픽 전산시스템의 기술성과를 직접적으로 계승하거나 소유권을 주장하거나 못했다. 그럼에도 불구하고 개발 과정에서 축적된 기술, 하드웨어, 인력은 이후 여러 영역으로 확산하여 한국 정보통신기술 발전의 밑거름이 되었다.

• Genomics & Informatics
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• 제6권4호
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• pp.227-230
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• 2008

Compounds of polyketide origin possess a wealth of pharmacological effects, including antibacterial, antifungal, antiparasitic, anticancer and immunosuppressive activities. Many of these compounds and their semisynthetic derivatives are used today in the clinic. Most of the gene clusters encoding commercially important drugs have also been cloned and sequenced and their biosynthetic mechanisms studied in great detail. The area of biosynthetic engineering of the enzymes involved in polyketide biosynthesis has recently advanced and been transferred into the industrial arena. In this work, we introduce a computational system to provide the user with a wealth of information that can be utilized for biosynthetic engineering of enzymes involved in post-PKS tailoring steps. Post-PKS tailoring steps are necessary to add functional groups essential for the biological activity and are therefore important in polyketide biosynthesis.

• 산업경영시스템학회지
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• 제20권44호
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• pp.163-169
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• 1997

Due to the increasing of the number of cars and bad road conditions, car accidens are increasing every you in Korea. When a person meets a car accident, it is necessary for him to analyze and determine whether applying insurance or not, because standard discount rate and special increasing rate change with accident types and the amount of accident expenditure. When we consider insurance rate that includes more then ten elements, we need a decision making, In this paper, S insurance company investigated previous car causers in 1988, 1989, 1990 to 1996 with 600,000 real data. We investigate probability density functions and cumulative distribution functions for each year using ARENA software. We can apply the results of this study to various accidents that occur under uncertainty in our life. I hope that this paper contribute to strengthening competitive power of companies and developing new insurance rate systems in future.

• Toxicological Research
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• 제19권3호
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• pp.247-257
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• 2003

Medicine is undergoing a revolution in the understanding of the mechanisms through which disease processes develop. The advent of genetics and molecular biology to oncology not only is providing surrogate predictors of therapy response and survival which are forming the basis for selection among established treatment options, but is providing targets for new directions in therapy as well. Molecular modification of somatic cells for the purposes of protecting the normal cells from the toxicity of cancer chemotherapy, for the sensitization of the tumor cells to therapy and use of conditionally replicating viral vector have been new directions of cancer treatment which have reached the clinical arena. Advances in molecular pharmacology and vector design summarized in this paper may provide solutions to some of the existing problems in the technology of gene transfer therapy. Continued basic research into the biological basis of human disease, systemic studies of the application of these discoveries to therapy and the improvement of vector for gene delivery all combined may result in advances in this important field of therapy over the next few years.

• Imaging Science in Dentistry
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• 제44권3호
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• pp.177-183
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• 2014

Recent research in endodontics has highlighted the need for three-dimensional imaging in the clinical arena as well as in research. Three-dimensional imaging using computed tomography (CT) has been used in endodontics over the past decade. Three types of CT scans have been studied in endodontics, namely cone-beam CT, spiral CT, and peripheral quantitative CT. Contemporary endodontics places an emphasis on the use of cone-beam CT for an accurate diagnosis of parameters that cannot be visualized on a two-dimensional image. This review discusses the role of CT in endodontics, pertaining to its importance in the diagnosis of root canal anatomy, detection of periradicular lesions, diagnosis of trauma and resorption, presurgical assessment, and evaluation of the treatment outcome.

• Wind and Structures
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• 제18권2호
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• pp.117-134
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• 2014

It is believed that offshore wind farms may satisfy an increasing portion of the energy demand in the next years. This paper presents a comparative study of the fatigue performances of tripod and jacket steel support structures for offshore wind turbines in waters of intermediate depth (20-50 m). A reference site at a water depth of 45 m in the North Atlantic Ocean is considered. The tripod and jacket support structures are conceived according to typical current design. The fatigue behavior is assessed in the time domain under combined stochastic wind and wave loading and the results are compared in terms of a lifetime damage equivalent load.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2004년도 봄 학술발표회 논문집
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• pp.151-160
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• 2004

Genetic algorithm is the theory of grafting the principle of survival of the fittest in genetics on to the computer algorithm and it is used to solve the optimization problems, especially the shape and size optimization of the structure in Architectural problems. In the size optimization problem discrete variables are used, but series variables have to be used in the shape optimization problem because of the incongruenty. The purpose of this study is to obtain the optimum shape of cable domes by using the real coding genetic algorithm. Generally, the structural performance of the cable domes is influenced very sensitively by pre-stress, geometry and length of the mast because of its flexible characteristic. So, it is very important to decide the optimum shape to get maximum stiffness of cable domes. We use the model to verify the usefulness of this algorithm for shape optimization and analyze the roof system of Seoul Olympic Gymnastic Arena as analytical model of a practical structures. It is confirmed lastly that the optimum shape domes have more stiffness than initial shape ones.

• 대한안전경영과학회지
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• 제11권4호
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• pp.193-199
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• 2009

Recently, an industrial production-distribution planning problem has been widely investigated in Supply Chain Management(SCM). One of the key issues in the current SCM research area is reverse logistics network. This study have developed a simulation model for the reverse logistics network. The simulation model analysis reverse logistics network issues such as inventory policy, manufacturing policy, transportation mode, warehouse assignment, supplier assignment. Computational experiments using commercial simulation tool ARENA show that the real problems. The model can be used to decide an appropriate production-distribution planning problem in the research area.

• 정신신체의학
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• 제4권2호
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• pp.286-293
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• 1996

The studying and teaching of behavioral neurology remain in their infancy. As the arena for studying how the brain subserves cognition, emotion and consciousness, behavioral neurology straddles the boundaries of numerous, more established disciplines-extending from the most fundamental explorations of molecular biology to the broadest questions of philosophy. In behavioral neurology, the area of neural dysfunction as well as the pathogenesis must be determined. There are cases in which a more thorough mental status examination must be performed. These are practically the cases with known or suspected brain lesions and acute psychiatric disorders.

• 기술경영경제학회:학술대회논문집
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• 기술경영경제학회 1997년도 제12회 동계학술발표회 논문집
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• pp.70-88
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• 1997

Recently, the interdisciplinary linkage between engineering and social science has received an increasing attention as an emerging education discipline. Due to intrinsic complexity of innovation process and heterogeneity of disciplinary nature, however there exists little, if not no, effort to draw a common framework in terms of educational scope and contents of the new subject. This paper presents a number of criteria and guidelines for building up new educational framework by integrating engineering subject and social science subject. Specifically, three neo-disciplines, technology policy, technology management, and economics of technology are considered since it is postulated that the forementioned disciplines have established academic identity and fundamental structure By nature, this paper is an exploratory and seminal one. It is not the purpose of this paper to provide a concrete table of contents of educational material. Instead, it merely brings up a discussion topic for the wide audience of academic arena, leaving the gradual consensus and convergence as future task.