• Title/Summary/Keyword: approach paradigm shift

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Neurovascular Mechanisms in Stroke, Neurodegeneration and Recovery

  • Lo, Eng-H.
    • The Korean Journal of Physiology and Pharmacology
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    • v.10 no.5
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    • pp.223-229
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    • 2006
  • The emerging concept of the 'neurovascular unit' may enable a powerful paradigm shift for neuroscience. Instead of a pure focus on the 'neurobiology' of disease, an opportunity now exists to return to a more integrative approach. The neurovascular unit emphasizes that signaling between vascular and neuronal compartments comprise the basis for both function and dysfunction in brain. Hence, brain disorders are not just due to death of neurons, but instead manifested as cell signaling perturbations at the neurovascular interface. In this mini-review, we will examine 3 examples of this hypothesis: neurovascular mechanisms involved in the thrombolytic therapy of stroke, the crosstalk between neurogenesis and angiogenesis, and the link between vascular dysfunction and amyloid pathology in Alzheimer's disease. An understanding of cell-cell and cell-matrix signaling at the neurovascular interface may yield new approaches for targeting CNS disorders.

Research System Design for Creative Innovation in the National R&D Program : The Case of Creative Research Initiatives in Korea (창조적 혁신을 위한 국가연구개발사업 연구추진체제의 설계 : 창의적연구진흥사업 사례)

  • 손병호;현재호
    • Journal of Technology Innovation
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    • v.7 no.1
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    • pp.60-77
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    • 1999
  • This study addresses the question of how to design the research system for national R&D programs that aim to promote creative innovation. This paper attempts to analyze the case of Creative Research Initiatives(CRI), a new national R&D program recently launched by the Ministry of Science and Technology of Korea. CRI is a strategic program intended to shift the national R&D paradigm from imitative innovation to creative innovation. The key features of the research system of the program include: a research-centered system, long-term research funding, the sunset approach, a dynamic and flexible research organization, and a centralized research system. This paper suggests theoretical rational of these key features based on the literature review on creative innovation. Based on an analysis of the results of implementing the CRI in 1997, this paper also examines how the research system design is reflected and embodied in the program implementation process. Finally, policy implications and future research directions are also discussed.

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A Study on Paradigm Shift of Supply Chain Risk Management for SMEs (중소기업에서의 공급사슬 위험관리를 위한 패러다임 전환에 관한 연구)

  • Yoon, Seung-Ok;Lee, Chang-Ho
    • Journal of the Korea Safety Management & Science
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    • v.14 no.4
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    • pp.71-77
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    • 2012
  • It is very important the collaboration and risk management of supply chain between the parent company and its partners in the supply chain risk management(SCRM). It was known that the SCRM approach is very different between a large enterprise and a small and medium-sized enterprise. This paper deals with the suggestion about SCRM structure for a small and medium-sized enterprise. This SCRM structure consist of risk identification, risk assessment, and risk mitigation. We expect that this SCRM structure promote the collaboration between a parent company and its partners to alleviate the supply chain risk.

Modeling of Public Risk Perception and Risk Communication Research: In A Social-Cognitive Direction

  • Li, Yiwei;Guo, Yu;Ito, Naoya
    • Asian Journal for Public Opinion Research
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    • v.1 no.3
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    • pp.217-231
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    • 2014
  • This study begins with a review of commonly discussed dimensions of public risk perception that may influence public opinion toward risks. Factors that have been revealed by the literature to have substantial impact on risk perception, such as demographic background, trust, and media environment, are also discussed. Meanwhile, we evaluate two well-known research models in the realm of risk analysis: 1) the psychometric paradigm, and 2) the social amplification of risk framework (SARF). Based on a literature review, this study suggests that, besides the psychological and social approach, models of risk perception and risk communication research should shift to a more comprehensive one by considering the interrelations between laypeople and the environment. This study proposes a research model from the perspective of social cognitive theory (SCT) as a potential framework for future studies: 1) in the societal environment, individuals' risk perception and information seeking behavior, which is determined by risk perception will be influenced by trust in regulators and interpersonal trust; 2) in the media environment, individuals' risk perception and information seeking behavior will be influenced by individuals' perceived information characteristics. Knowledge about risk accumulated through information seeking will change risk perception in a longitudinal process.

Characteristics of Consumers' Purchasing Behavior and Conscious : Focused on Condominium Housing in Japan (아파트 구매에 관한 소비자의 구매행동과 의식 특성 - 일본 신규 분양아파트 구매자를 대상으로 -)

  • Choi Jung-Min;Kang Soon-Joo
    • Journal of the Korean housing association
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    • v.16 no.5
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    • pp.29-38
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    • 2005
  • Recently there has been an apparent paradigm shift in housing market towards customer oriented approach. In the midst of increasing competition, there is indeed a need to better understand of customers, and to quickly respond to their individual needs and wants. In this background, this paper aims to show a scientific marketing approach in housing industries, and to provide general information on Japanese condominium housing market in terms of a brief historical overview and recent market situation. Results include that there exists an about twenty year time lag in the start of condominium housing supply in the private sector between Korea and Japan. Besides, more efforts should be paid to the diversity or locality of the supplied housing type or design, especially condominium apartments in Korea compared to those of Japan. Among others this paper emphasized on illustrating the actual applications of analysis on consumers' purchasing behavior and latent conscious coupled with some statistical techniques, which may lead marketers or decision makers to forecast more accurate customers demands.

Indexing of XML with B+-tree (B+-tree를 이용한 XML 색인기법)

  • Kwon, Guk-Bong;Hong, Dong-Kweon
    • Journal of the Korean Institute of Intelligent Systems
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    • v.16 no.1
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    • pp.94-100
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    • 2006
  • Computing paradigm shift to internet-based one has accelerated the use of XML in diverse applications. This phenomena has made the explosive increases of XML data and it triggered many active researches in maintaining very huge amount of XML data in turn. In this paper we present a persistent graph-based XML indexing lot data-centric XML data. In our approach we use 3 graphs to represent XML indexes and XML data itself. They are schema graph, data graph index. And then we have mapped those graphs to B+-trees the persistency. With our approach we can achieve linear query execution time with the increase of XML sizes.

New method environment for art design of nanocomposite brick facade of the building

  • Jie Xia;Gholamreza Soleimani Jafari;F. Ghoroughi
    • Steel and Composite Structures
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    • v.51 no.5
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    • pp.499-507
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    • 2024
  • The paper delves into an emerging paradigm shift in architectural design, focusing on the development of a cutting-edge methodological framework for the artistic enhancement of nanocomposite brick facades in building construction. This innovative approach represents a fusion of art and science, harnessing the potential of advanced nanotechnology to redefine the aesthetic and functional properties of building exteriors. Central to this new methodology is the integration of state-of-the-art materials and fabrication techniques, aimed at not only elevating the visual appeal of architectural structures but also enhancing their structural robustness and environmental sustainability. By leveraging the unique characteristics of nanocomposite materials, the proposed method opens up new possibilities for pushing the boundaries of traditional brick facade design. Through a meticulous exploration of the intricacies involved in implementing this novel approach, the paper elucidates the transformative impact it can have on the architectural landscape. By marrying creativity with technical precision, the method environment for art design of nanocomposite brick facades promises to usher in a new era of sustainable, visually captivating, and structurally resilient building facades that are poised to redefine the very essence of architectural aesthetics.

Regulatory Reform for Service Development (서비스발전을 위한 규제개혁의 새 패러다임)

  • Jeong, Ki-Oh
    • Journal of Service Research and Studies
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    • v.6 no.3
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    • pp.1-15
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    • 2016
  • Despite that Korea has tried radical efforts in the global flow of regulatory reform in the past twenty years, the result was not radical at all, but rather disappointing. One examines the possibility of paradigm shift in regulatory reform based on new theoretic perspectives. Regulatory reform, one argues, is not just a neo-liberal approach to cut off overflowing regulation. It is a highly conflictual struggle in state order to move from industrial age paradigm to service age paradigm. In the process of the great shift states become integrated into the world of life constructed by the exercise of civil rights. The relation between the civic socio-economic life and the state apparatus became totally different. Past effort for deregulation missed this point without correct recognition of the role of civil freedom and rights in service economy. One treats three typical forms of regulation whereby conventional rules and regulations effectively damper the development of services: reciprocal perspective in contract management, industrial mind in urban and spaces design, and old way of human capital management. According these analyses a new initiative of regulatory reform is proposed to take place at the National Assembly.

New Approach to the Framework for Making the S&T Information Infrastructure in Complex System (복잡계 상황에서의 새로운 과학기술정보인프라구축의 틀 모색)

  • WON, DONG KYU;SUH, JEE HYUN
    • Proceedings of the Korea Contents Association Conference
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    • 2007.11a
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    • pp.188-192
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    • 2007
  • Today, the most pivotal issue in the national research and development, and national scientific and technical policy is to overcome uncertainties in the environment of technology development. The social and economic environment around us is at restricted uncertainty (complex system) where order and disorder coexist. Furthermore, the environment of technology development is more complicated. In order to bring about creativity in practices of technology development, we need a paradigm shift towards a new framework for the construction of the national scientific and technical information infrastructure, which entails a shift to creativity, self-organization and dynamic capability. The paradigm shift will lead the present scientific and technical information infrastructure which centers on information sharing, to move towards one that enables information coherence through self-organization. Thus, it is expected that the new Web 3.0 will provide a client-flexible analysis information system that will make information coherence and feedback possible. Through this system, the policy for the construction of a new scientific and technical infrastructure will evolve, which will bring about co-evolution of individual's knowledge through sharing of self-organizaed knowhow.

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The Scope of Practice for Registered Nurses in 64 South Korean Laws

  • Choi, Sungkyoung;Jang, Seung Gyeong;Lee, Won
    • Journal of Korean Academy of Nursing
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    • v.49 no.6
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    • pp.760-770
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    • 2019
  • Purpose: The role of registered nurses is expanding in scope as the healthcare paradigm shifts from acute, hospital-based care to community and population-based care. Given this paradigm shift, this study explores the legal aspects of the role of a registered nurse. Methods: We used document analysis for extracting laws and legal orders related to nursing from the entirety of Korean law. Using textualism approach, we examined the contents utilizing a framework that was developed based on the role classification of community nurses by Clark in this study. Results: A total of 119 items related to nursing were derived from 64 laws. Of these, 71.4 % can be performed by people in multiple types of occupations including nurses. As a result of analyzing required qualifications, 45.4% of 119 items required additional qualifications besides registered nurse license. Analysis of workplace and activity type demonstrated that 26.1% of the 119 items were related to medical institutions, with nurses performing mostly "Client-oriented role." More than half (68.9%) were non-medical institutions, with nurses performing mostly "Delivery-oriented role." Some, however, did not stipulate the nurse's roles clearly. Conclusion: Therefore, to match the enhanced scope and responsibilities of registered nurses and to appropriately recognize, guide, and hold these nurses accountable, laws and policy must reflect these changes. In doing so, these updated laws and policies will ultimately serve as a basis for improving the quality and safety of nursing services.