• Journal of the Korean Society for Precision Engineering
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• v.28 no.7
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• pp.859-865
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• 2011

A bio-check unit and health index were developed to provide information on personal health state with easily available noninvasive measurements and surveys. Four health indices were defined such as cardiovascular index, stress index, obesity index, and management index. Methods were developed to calculate health index scores from measured physiological signals and answer of survey questions. In order to evaluate effectiveness of the health indices, a clinical trial was conducted for 362 persons who visited general hospital for annual health inspection. The cardiovascular index showed a good correlation coefficient of 0.685 with the cardiovascular health graded by a medical doctor. The stress index showed a good correlation coefficient of 0.638 with the results of stress questionnaires being used in the public health center. Once the health index function is added in the bio-check unit, the unit may provide useful contents for personal health management.

• Journal of the Korean Applied Science and Technology
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• v.37 no.2
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• pp.287-295
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• 2020

The purpose of this study is to analyze what constitutes the sympathetic component of nurses care of dementia patients. For this study, 219 nurses in nursing dementia patients were treated in nursing hospitals. Using the Empathy Consensus Rating Scale (ECRS), basic model extraction, model modification, and model suitability verification were performed through factor structure search and confirmation factor analysis (CFA). The results of this study confirmed the validity and reliability of the constituents with 49 questions, including 3 factors including the acceptance of other emotions, the suppression of one's own emotions, and the exchange and interaction of emotions. According to these results, it is expected that the ECRS that can secure validity and reliability can be used for the study to confirm the nurse's Empathy in the dementia patients' nursing field.

• Bulletin of the Korean Chemical Society
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• v.28 no.12
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• pp.2303-2309
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• 2007

Expressed protein ligation (EPL) technique, joining recombinantly expressed proteins to polypeptides, has been widely adopted for addressing various biological questions and for drug discovery. However, joining two recombinant proteins together is sometimes difficult when proteins are expressed insoluble and unrefoldable, because ligation-active proteins via intein-fusion are obtainable when they are folded correctly. We overcame this limitation coexpressing target protein with additional methionine aminopeptidase (MAP) which enhances removal of the initiation methionine of recombinantly expressed protein. Our approach demonstrated that two domains of 46 kDa 5-Enolpyruvylshikimate-3-phosphate (EPSP) synthase, a target of herbicide glyphosate, were successfully joined by native chemical ligation, although its C-terminal domain was expressed as an inclusion body. The intein-fused N-terminal fragment of EPSP synthase (EPSPSN, residues 1-237) was expressed and the ligation-active thioester tagged N-terminal fragment (EPSPSN-thioester) was purified using a chitin affinity chromatography and mercapto-ethanesulphonate (MESNA) as intein thiolysis reagent. Its Cterminal fragment (EPSPSC, residues Met237-238CYS-427), expressed as an inclusion body, was prepared from an additional MAP-expressing strain. Protein ligation was initiated by mixing ~1 mM of EPSPSN-thioester with ~2 mM of EPSPSCCYS (residues 238CYS-427). Also we found that addition of 2% thiophenol increased the ligation efficiency via thiol exchange. The ligation efficiency was ~85%. The ligated full-length EPSP synthase was dissolved in 6 M GdHCl and refolded. Circular dichroism (CD) and enzyme activity assay of the purified protein showed that the ligated enzyme has distinct secondary structure and ~115% specific activity compared to those of wild-type EPSP synthase. This work demonstrates rare example of EPL between two recombinantly expressed proteins and also provides hands-on protein engineering protocol for large proteins.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.7 no.5
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• pp.853-862
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• 2003

With the data base subject of first grade paper test of information handling technician, We proposed special method of evaluating learning ability directivity to judge that student can understand the contents of each chapter exactly or not, using assigned function and fuzzy deduction in this thesis. Using fuzzy logic, the proposed method of evaluating learning ability is dividing the presenting frequency of setting questions for examination about the subject of database into three rank and we can define this as the important. We applied the fuzzy assigned rate about the number of times of studying through the important of studying and the fuzzy assigned rate about formative evaluation to each of nine fuzzy deduction theories and than evaluated comprehension rate of learning. With the fuzzy grade about learning comprehension of each chapter and assigned rate about the score of generalized evaluation; We applied these two thing to the deduction rule of fuzzy and made it as defuzzifier and finally evaluated learning. We made that the result of eventual evaluating learning is very useful for learners to diagnosis learned contents by themselves and also it can be great material to judge that learners can get the goal of learning or not synthetically.

• Journal of Korean Elementary Science Education
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• v.34 no.2
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• pp.252-263
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• 2015

This study analyzed the effects of science outdoor activity applying a Brain-Based Evolutionary (ABC-DEF) approach on elementary school students' interest and academic achievement. Samples of the study were composed of 3 classes of 67 sixth graders in Seoul, Korea. Unit of 'Ecosystem and Environment' was selected as a object of the research. Textbook- and teachers' guidebook-based instruction was implemented in comparison group, brain-based evolutionary approach within classroom in experimental group A, and science outdoor learning by a brain-based evolutionary approach in experimental group B. In order to analyze the quantitative differences of students' interests and achievements, three tests of 'General Science Attitudes', 'Applied Unit-Related Interests', and 'Applied Unit-Related Achievement' were administered to the students. To find out the characteristics which would not be apparently revealed by quantitative tests, qualitative data such as portfolios, daily records of classroom work, and interview were also analyzed. The major results of the study are as follows. First, for post-test of interest, a statistically significant difference between comparison group and experimental group B was found. Especially, the 'interests about biology learning' factor, when analyzed by each item, was significant in two questions. Results of interviews the students showed that whether the presence or absence of outdoor learning experience influenced most on their interests about the topic. Second, for post-test of achievement, the difference among 3 groups according to high, middle, and low levels of post-interest was not statistically significant, but the groups of higher scores in post-interest tends to have higher scores in post-achievement. It can be inferred that outdoor learning by a brain-based evolutionary approach increases students' situational interests about leaning topic. On the basis of the results, the implications for the research in science education and the teaching and learning in school are discussed.

• Education of Primary School Mathematics
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• v.20 no.2
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• pp.177-192
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• 2017

In theory, mixed methods that incorporate both quantitative and qualitative approaches can maximize strengths of each method while minimize the short comings of each. Mixed methods research is a feature of educational research nowadays, and the number of studies applied mixed methods research has been gradually increasing. This study investigates how mixed methods research was applied in the field of mathematic education, especially focusing on how qualitative and quantitative methods are combined to best address their research questions. With this in mind, this study carefully selects and analyzes 4 research articles that used mixed methods and were published by Journal of Elementary Mathematics Education in Korea in 2015. This study provides detailed result of qualitative analysis on mixed methods research while other a few previous analysis on mixed methods research were tend to focusing on quantitative analysis, producing numeric quantitative information. The result of this study provides practical and in-depth analysis on how to improve validity and possibility of mixed methods research, addressing alternative ways to combine two different research methods and key elements to take into account.

• Journal of Korean Society for Quality Management
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• v.43 no.3
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• pp.359-372
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• 2015

Purpose: Through studying the expert's and non-experts panel responses to the questions regarding the attributes of chemical-biological protection cloth quality in terms of the levels of customer demand and technical factors has been studied. We are applied to a QFD matrix with find out the relationship between the selective removal efficiency of chemical-biological cloth and the guidelines of technical approach. Methods: We fabricated several composite of ion-exchange resins with selectively permeable performance designed to facilities water vapor transport and selective adsorption of the harmful gases. With these materials, we characterized on the selectively permeable performance to identify ion-exchange resin with chemical-biological protective cloth. Results: Results showed that ion exchange materials possessed performance with selectively efficiencies as NH3, SOx, NOx and HCl gas. The selective adsorption amount of ammonia and hydrogen gases were $90-80{\mu}g/g$ with TRILITE SCR-BH sulfonated ion exchange resin. The PP non-woven/ion exchange resin adsorbent materials possessed performance with water vapor permeability were 1,100-1,350 g/m2/day, it's was two times high value compare with activated carbon. With these materials, we characterized selectively removal efficiency to identify new ion-exchange material with chemical-biological protective capability. Conclusion: This study shows that a QFD aids in deciding with of the adsorption parameters to optimized with chemical-biological protection cloth manufacturing.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.5
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• pp.1071-1077
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• 2008

Hwa-byung is a form of psychogenic illness among people in Korea and is listed as a culture-bound syndrome of Korea in the DSM-IV. Despite increased clinical researches for Hwa-byung in the oriental medicine of Korea, there has been no agreement of pattern identification for Hwa-byung. The purpose of this study is to develop a standard instrument of pattern identification for Hwa-byung which will be applied to clinical research. The items and structure of the instrument were based on review of published literature. The advisor committee on this study was organized by 15 neuropsychiatry professors of 11 oriental medical colleges nationwide. The experts attended 2 consultation meetings and discussed developing the instrument. and we also took professional advices by e-mail. The results were as follows; First, we divided the symptoms and signs of Hwa-byung into five pattern identification - stagnation of liver Qi, flare-up of the liver fire, disharmony between heart and kidney, deficiency of both Qi and blood, malfunction of gallbladder due to phlegm stagnation. Second, we got the mean weights to each symptom of five pattern identification which had been scored on a 5-point scale - ranging from 0 to 4 by the 15 experts. Third, we made out the Korean instrument of the pattern identification for Hwa-byung. It was composed of 34 questions and decided on question-and-answer form. Though there are some limits in this study, the instrument of pattern identification for Hwa-byung is meaningful and expected to be applied to the subsequent research. And also, we hope to improve the instrument and make up for this study through various research and discussion.

• The Mathematical Education
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• v.57 no.3
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• pp.289-309
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• 2018

There has been a gradually increasing focus on adopting mathematical modeling techniques into school curricula and classrooms as a method to promote students' mathematical problem solving abilities. However, this approach is not commonly realized in today's classrooms due to the difficulty in developing appropriate mathematical modeling problems. This research focuses on developing reformulation strategies for those problems with regard to mathematical modeling. As the result of analyzing existing textbooks across three grade levels, the majority of problems related to the real-world focused on the Operating and Interpreting stage of the mathematical modeling process, while no real-world problem dealt with the Identifying variables stage. These results imply that the textbook problems cannot provide students with any chance to decide which variables are relevant and most important to know in the problem situation. Following from these results, reformulation strategies and reformulated problem examples were developed that would include the Identifying variables stage. These reformulated problem examples were then applied to a 7th grade classroom as a case study. From this case study, it is shown that: (1) the reformulated problems that included authentic events and questions would encourage students to better engage in understanding the situation and solving the problem, (2) the reformulated problems that included the Identifying variables stage would better foster the students' understanding of the situation and their ability to solve the problem, and (3) the reformulated problems that included the mathematical modeling process could be applied to lessons where new mathematical concepts are introduced, and the cooperative learning environment is required. This research can contribute to school classroom's incorporation of the mathematical modeling process with specific reformulating strategies and examples.

• The Korean Journal of Applied Statistics
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• v.29 no.1
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• pp.231-242
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• 2016

X-13-ARIMA (a popular time series analysis software) provides $3{\times}3$, $3{\times}5$, $3{\times}9$, $3{\times}15$ moving average filters for seasonal adjustment. However, there has been questions on their performance and the need for new filters is a constant topic due to Korean economic time series often containing higher irregularity and more various seasonality than other countries. In this study, two newly developed seasonal moving average filters, $3{\times}7$ and $3{\times}11$, are introduced. New filters were implemented in X-13-ARIMA and applied to 15 economic time series to demonstrate their suitability and reliability. The result shows that some series are more stable when using new seasonal moving average filters. More accurate time series analyses would be possible if newly proposed filters are used together with existing filters.