• Korean Journal of Biological Psychiatry
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• v.24 no.1
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• pp.39-44
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• 2017

Objectives Angiotensin-converting enzyme (ACE) gene and plasma levels of cytokines, such as tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-10 (IL-10), have previously been determined to be associated with depression. The purpose of this study was to investigate the association of plasma levels of ACE and cytokines with recurrent depression. Methods A total of 52 participants (14 male, 38 female, aged $43.9{\pm}14.0years$) were enrolled after being diagnosed with depression by experienced psychiatrists using the Mini International Neuropsychiatric Interview from the outpatient clinic of the Department of Psychiatry, CHA Bundang Medical Center. The participants completed blood sampling, the Hamilton Depression Rating Scale (HAMD), the Beck Depression Inventory, the Beck Anxiety Inventory, and the Scale for Suicidal Ideation. Results ACE plasma levels are higher in patients with recurrent depression ($27.4{\pm}10.4U/L$) than in patients with newly diagnosed depression ($19.1{\pm}7.7U/L$) (p = 0.004). The levels of cytokines, such as $TNF-{\alpha}$, IL-4, IL-6, IL-10, are not significantly different between the two groups. Additionally, the ACE plasma level is negatively correlated with a reduction in the HAMD over six weeks (r = -0.429, p = 0.046, n = 22). Conclusions The current findings show that plasma ACE levels may be associated with recurrent depression and further suggest that the renin-angiotensin system could play a role in recurrent depression.

• Journal of Oriental Neuropsychiatry
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• v.21 no.2
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• pp.157-169
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• 2010

Objectives : The aim of this study was to investigate the characteristics of Hwa-Byung(HB) patients, draw the clinical key issue of HB, and provide the data as the basis for development of Clinical Guideline of HB. Methods : The study participants included 151 subjects who thought they have HB in 9 site. For all patients, we used HB epidemiologic study protocol, which include the Korean version of the Structured Clinical Interview for the DSM-IV Diagnosis (SCID-1), diagnostic criteria of HB, symptoms check list, pattern identification tool, psychiastric psychological questionaires, and Framingham coronary risk score(FRS). Results : 1. For all participants, 62 % of subjects were diagnosed with HB. These patients had comorbid DSM-IV diagnoses with depression (65%) and anxiety (27%). But 22% of these patients had only HB. 2. HB patients had various physical symptoms when visiting, were diagnosed as various disease, and undergone medical treatments in the past. Among the diagonsed illness, Gastronitestinal diseases (51.6%), psychiatric disorders(40.9%), endocrine diseases(39.8%) were being the most frequent. The frequent physical symptoms of HB patients reported were chest discomfort, head ache, pallpitation, frequent sigh, amnesia, shoulder pain, dry mouth, eye fatigue etc. 3. HB patients had high scores in psychologic questionares, CES-D, STAI, and STAXI. It means that HB patients might be low-level emotional stability. 4. Participant had negative opinion about the treatment of HB that it would be difficult or impossible (65.7%), but they neglect the need of medical treatment. Conclusions : This result shows that HB is comorbid with various psychiatric disease, but it has different physio-psychological symptoms from others and there were only HB patients. so we identify HB is independent disease. Moreover, there were the wrong perception of HB which blocking treatments. These problems support that the neccesity of development of Clinical Guideline of HB.

• Fire Science and Engineering
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• v.33 no.3
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• pp.154-165
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• 2019

This study was conducted to investigate whether ego - resilience plays a mediating role in the relationship between adult attachment and job stress of fire officers, and to derive implications for job stress reduction of fire officers. A questionnaire survey was conducted for 480 fire officers working in Seoul and Gyeonggi - do, and correlation analysis and regression analysis were conducted using SPSS 21.0. The results showed that there was a negative correlation between instability attachment and job stress in adult attachment, negative correlation between instability attachment and ego - resilience in adult attachment, and negative correlation between ego - resilience and job stress. Adult attachment and ego - The results showed that there was a statistically significant effect on stress. Ego - resilience was found to full mediate the effect of anxiety of adult attachment on job stress and to partial mediate the effect of avoidance on job stress. This study suggests the need to develop a program that can improve ego - resilience considering the importance of ego - resilience and the occupational characteristics of fire officer. This means that the psychological and psychological factors of the individual should also be considered in order to reduce the level of job stress of the fire service personnel.

• Archives of Plastic Surgery
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• v.39 no.5
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• pp.540-545
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• 2012

Background Patients have anxiety and fear of complications due to general anesthesia. Through new instruments and local anesthetic drugs, a variety of anesthetic methods have been introduced. These methods keep hospital costs down and save time for patients. In particular, the target-controlled infusion (TCI) system maintains a relatively accurate level of plasma concentration, so the depth of anesthesia can be adjusted more easily. We conducted this study to examine whether intravenous anesthesia using the TCI system with propofol and remifentanil would be an effective method of anesthesia in breast augmentation. Methods This study recruited 100 patients who underwent breast augmentation surgery from February to August 2011. Intravenous anesthesia was performed with 10 mg/mL propofol and 50 ${\mu}g/mL$ remifentanil simultaneously administered using two separate modules of a continuous computer-assisted TCI system. The average target concentration was set at 2 ${\mu}g/mL$ and 2 ng/mL for propofol and remifentanil, respectively, and titrated against clinical effect and vital signs. Oxygen saturation, electrocardiography, and respiratory status were continuously measured during surgery. Blood pressure was measured at 5-minute intervals. Information collected includes total duration of surgery, dose of drugs administered during surgery, memory about surgery, and side effects. Results Intraoperatively, there was transient hypotension in two cases and hypoxia in three cases. However, there were no serious complications due to anesthesia such as respiratory difficulty, deep vein thrombosis, or malignant hypertension, for which an endotracheal intubation or reversal agent would have been needed. All the patients were discharged on the day of surgery and able to ambulate normally. Conclusions Our results indicate that anesthetic methods, where the TCI of propofol and remifentanil is used, might replace general anesthesia with endotracheal intubation in breast augmentation surgery.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.715-721
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• 2018

This study examined energy saving and elevating the worker's neuro energy (comfort, concentration, physical, and psychological stability) by compensating for the unpleasant tactile sensation to stimulate auditory and olfactory senses and reduce energy consumption. The experiment was conducted in an environment test room under the test conditions of temperature $25[^{\circ}C]$, relative humidity 50[RH%], illumination 1,000[lux] and air current speed 0.02[m/sec] by stimulating the auditory senses with a 1/f change in rhythm and the olfactory senses with an aroma scent. The experiment utilized the method of EEG, which evaluates human body's psychological status via tactile means, and the method of the vibra image, which evaluates the learning abilities, HRV and human body's psychological status via non-tactile means. The subjects were selected as eight university students (four males and four females) in their 20s, the type that have high relative ${\alpha}$(8~13[Hz]) activation in occipital lobe, which brings the highest level of mind stability and concentration, who had no difficulty in physical activities. The subjects' posture and physical activity was fixed to 1met - when the subjects are seated and relaxing in a comfortable environment - and their clothes condition was standardized as 0.7clo. As a result, the sentimental and psychological stability and concentration were the highest in the multisensory stimulation of jasmine scent and change rhythm of an a=1.106 sound source. In addition, under this condition, the relative $M{\alpha}$ and relative $M{\beta}$ increased by 70.49[%] and 89.72[%], respectively; the HRT decreased by 39.09[%]; and the fatigue and tension/anxiety decreased by 36.85[%] and 15.54[%], respectively.

• Herbal Formula Science
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• v.16 no.2
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• pp.1-9
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• 2008

Objective : The purpose of this report was to provide the information about activity and safety of Ojeok-san by analyzing domestic/international papers about Ojeok-san. Methods : Domestic/international papers related to Ojeok-san were reviewed and analyzed. These papers were then classified by year, experimental method and subject. Results : The following results were obtained in this study. 1. The studies of Ojeok-san started from 1984 and has continuously increased. The studies were mainly focused on experimental models rather than clinical studies. 2. By subject, papers related to safety were most common with 5 papers among 20 papers. Besides there were papers related to efficacy of analgesic, anti-hyperlipidemic, anti-blood stasis and treatment for uterine myoma. 3. The papers related to safety were mainly focused on the effect of Okeok-san on liver function, renal function or metal concentration of organs such as blood, brain, liver, kidney and bone. Ojeok-san proved to be safe, but more clinical studies regarding the safety are needed hereafter. 4. Papers related to analgesic, anti-pyretic, anti-phlogistic activities of Ojeok-san were in vivo studies, and other papers were about anti-hyperlipidemic activity, apoptosis inducing activity on uterine myeloma cell line and anti blood static activity on hydrocortisone acetate induced blood statis model. 5. Case reports were about anti-lipidemia, analgesic effect for mastalgia/back pain and anxiety disorder due to climacteric changes. Conclusion : Ojeok-san is being used in various ways with analgesic, anti-pyretic, anti-phlogistic, anti-hyperlipidemic, anti-tumor or anti-blood statis activity. However, mechanism study should be conducted at the molecular biology level and more clinical studies on the efficacy of Ojeok-san are needed.

• Journal of Korean society of Dental Hygiene
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• v.11 no.5
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• pp.811-822
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• 2011

Objectives : The purpose of this study was to examine the relationship of the self-efficacy of dental hygiene students to their stressors and ways of stress-adaptation patterns. Methods : The subjects in this study were dental hygiene juniors in four selected colleges located in the metropolitan area. Results : 1. They got a mean of 3.22 in self-efficacy. They gave the highest mark(3.50) to an item 'I can attain it if I set a primary goal.' 2. They got a mean of 3.18 in stressors. Among the stressors, task assignments(3.74) were identified as the greatest stressor, followed by the curriculum(3.25), learning environments(3.16), prospects of employment (3.07) and test anxiety(2.95). 3. They got a mean of 2.02 in stress-adaptation method. They got 2.31 and 1.72 in long-term and short-term adaptation respectively, which showed that long-term stress adaptation method were more prevailing than short-term ones. 4. As a result of analyzing whether there would be any gaps in self-efficacy according to general characteristics, statistically significant gaps were found in that regard according to experience of preparing for college admission after leaving high school, academic standing, satisfaction with the department of dental hygiene and prospects of employment(p<.05). 5. As a result of checking the relationship of their self-efficacy to their stressors and ways of stress adaptation method, there were statistically significant differences in that aspect according to examinations and prospect of employment(p<0.05). As for ways of stress adaptation method, there were statistically significant differences in long-term adaptation method (p<0.05). Conclusions : As it's found that the level of the self-efficacy of the dental hygiene students was linked to the efficiency of their ways of stress adaptation method, the development and implementation of programs geared toward boosting the self-efficacy of dental hygiene students are required to teach them to successfully cope with various kinds of stress that they are likely to face after getting a job.

• Journal of Korean society of Dental Hygiene
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• v.11 no.5
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• pp.671-683
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• 2011

Objectives : The purpose of this study was to examine the oral health knowledge and actual oral health care of the selected subjects, their decision making about prosthetic treatment, the state and characteristics of their prosthetic treatment and their satisfaction with prosthetic treatment in an attempt to provide some information on the improvement of the quality of life related to oral health and the promotion of oral health. Methods : The subjects in this study were 250 people who received education in two different lifelong education institutions in the city of Busan. After a survey was conducted from May 23 to June 15, 2011, the answer sheets from 217 respondents were analyzed. Results : 1. As for the general characteristics of the respondents, the men(52.1%) outnumbered the women. Those who were in their 60 and up(47.5%) made up the largest age group, and the married people(65.4%) outnumbered the unmarried ones. By occupation, the company employees(20.3%) made up the biggest group. By education, the greatest group was high-school graduates(36.1%). By monthly mean income, the biggest group gained an income of 2.01 million won or more(36.9%). As to medical security, community-based insurance was most prevailing (36.9%). In terms of health promotion, the largest group worked out to stay fit(52.4%). 2. Regarding oral health knowledge, they had a good knowledge about the cause of dental caries(56.7%), but they weren't well aware of the right time for regular dental checkup(47.9%). In relation to oral health care, regular scaling wasn't prevailing(16.9%). 3. Regarding connections between the general characteristics and satisfaction with prosthesis, the less-educated respondents expressed significantly more dissatisfaction(p=0.015). By monthly mean income, those who had a smaller income were dissatisfied in general(p=0.028). Conclusions : The findings of the study illustrated that it's required to spread awareness of the importance of oral health among people in general, and that differentiated incremental oral health care should be provided for different age groups. In order to raise the satisfaction of patients with prosthesis, how to relieve their pain and anxiety and how to adjust prosthetic treatment cost properly should carefully be considered. In addition, the government should take measures to offer assistance for the low-income classes in preparation for an increase in the elderly population.

• Journal of the Korean Society of Radiology
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• v.10 no.8
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• pp.583-590
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• 2016

The subjects in this study are the residents of Busan, analyzing the perception gap between the residents adjacent to the nuclear plant and living in town, about the lawsuit of thyroid cancer damage nearby the nuclear plant, to distinguish the citizen's acceptance level about the nuclear power. 551 people(269 people adjacent to nuclear plant, 282 people in town) were face-to-face surveyed and the result showed that people's perceptions of the nuclear power has changed after the thyroid cancer damage lawsuit. In the case of the residents adjacent to the nuclear plant, it became clear that the negative perception of nuclear power became stronger due to increasing distrust and anxiety about nuclear power after the lawsuit of thyroid cancer damage nearby the nuclear plant. On the other hand, people living in town showed their positive perceptions of nuclear power despite the thyroid cancer damage lawsuit. However, two-sided perception was shown compared to the acceptance of nuclear power, since the safety and reliability of the nuclear power was analyzed as negative perception. Therefore, for the constant increased use of nuclear power in the future, national understanding and credibility, including the communication with the nation or the residents in the neighboring area of nuclear power plant, will be necessary.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.11
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• pp.5522-5529
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• 2013

The purpose of this study was to look into the marketing strategies of social commerce companies by analyzing the relationships among the environment, strategy and performance in social commerce. For that, the environment condition and components of marketing strategy were derived based on the marketing mix by analyzing the related contents published in 3,783 articles on newspapers dated from April 2010 to March 2013. UV(Unique Visitor) and PV(Page View) for each social commerce site were used as surrogates for performance. The results of study revealed the relationship of the marketing strategies to the changes in environment conditions towards negative conditions such as the spread of buyer anxiety. In the "strategy-performance" relations, the product element and external sales promotion element had high correlation with the performance. Finally, a difference was found in the marketing strategies of social commerce companies. High correlation was found in all aspects between the UV and PV marketing elements in the case of Coupang, while the correlation with the UV was low and the environment also showed relatively low correlation level in the case of WEmakePRICE. Thus, this study is considered to provide useful basis for the social commerce companies to map out and implement the marketing strategies, and is significant in that it applied the marketing mix to the special market environment such as social marketing.